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| 1 | Final anatomic and visual outcomes appear independent of duration of silicone oil intraocular tamponade in complex retinal detachment surgery显示文摘AIM: To report anatomic and visual outcomes following silicone oil removal in a cohort of patients with complex retinal detachment, to determine association between duration of tamponade and outcomes and to compare patients with oil removed and those with oil in situ in terms of demographic, surgical and visual factors. METHODS: We reported a four years retrospective case series of 143 patients with complex retinal detachments who underwent intraocular silicone oil tamponade. Analysis between anatomic and visual outcomes, baseline demographics, duration of tamponade and number of surgical procedures were carried out using Fisher's exact test and unpaired two-tailed t-test. RESULTS: One hundred and six patients(76.2%) had undergone silicone oil removal at the time of review with 96 patients(90.6%) showing retinal reattachment following oil removal. Duration of tamponade was not associated with final reattachment rate or with a deterioration in best corrected visual acuity(BCVA). Patients with oil removed had a significantly better baseline and final BCVA compared to those under oil tamponade(P=0.0001, <0.0001 respectively). CONCLUSION: Anatomic and visual outcomes in this cohort are in keeping with those reported in the literature. Favorable outcomes were seen with oil removal but duration of oil tamponade does not affect final attachment rate with modern surgical techniques and should be managed on a case by case basis. | Maedbh Rhatigan Elizabeth Mc Elnea Patrick Murtagh Kirk Stephenson Elaine Harris Paul Connell David Keegan | 2018 | International Journal of Ophthalmology(English edition)2018，11，1： | 7 |
| 2 | Soy-based renoprotection显示文摘Chronic kidney disease(CKD) is a significant publich ealth problem as risk factors such as advanced age, obesity, hypertension and diabetes rise in the global po-pulation. Currently there are no effective pharmacologic treatments for this disease. The role of diet is important for slowing the progression of CKD and managing symptoms in later stages of renal insufficiency. While low protein diets are generally recommended, maintaining adequate levels of intake is critical for health. There is an increasing appreciation that the source of protein may also be important. Soybean protein has been the most extensively studied plant-based protein in subjects with kidney disease and has demonstrated renal protective properties in a number of clinical studies. Soy protein consumption has been shown to slow the decline in estimated glomerular filtration rate and significantly improve proteinuria in diabetic and non-diabetic patients with nephropathy. Soy's beneficial effects on renal function may also result from its impact on certain phy-siological risk factors for CKD such as dyslipidemia, hypertension and hyperglycemia. Soy intake is also associated with improvements in antioxidant status and systemic inflammation in early and late stage CKD pati-ents. Studies conducted in animal models have helped to identify the underlying molecular mechanisms that may play a role in the positive effects of soy protein on renal parameters in polycystic kidney disease, metabolically-induced kidney dysfunction and age-associated prog-ressive nephropathy. Despite the established relationship between soy and renoprotection, further studies are needed for a clear understanding of the role of the cellular and molecular target(s) of soy protein in main-taining renal function. | Nancy J Mc Graw Elaine S Krul Elizabeth Grunz-Borgmann Alan R Parrish | 2016 | World Journal of Nephrology2016，5，3： | 5 |
| 3 | Assessing cultural competency skills in gastroenterology fellowship training显示文摘AIM:To assess and teach cultural competency skills at the fellowship training level through the use of objective structured clinical examinations(OSCEs).METHODS:We revised four scenarios to infuse a specific focus on cross-cultural care,and to render them appropriate for gastroenterology fellows.Three are discussed here:(1)Poor Health Literacy;(2)Disclosing/Apologizing for a Complication to a Patient Who Mistrusts the Healthcare System;and(3)Breaking Bad News to a Fatalistic Patient.A fourth case emphasizing shared decision-making will be described elsewhere.Four stations were completed by fellows and observed live by four faculty members,and the fellows’performance was assessed.RESULTS:Eleven fellows from four programs participated in the four OSCE.In the'Poor Health Literacy'case,18%(2/11)of participants recognized that the standardized patient(SP)had below-basic health literacy.None successfully evaluated the SP’s reading skills in a culturally-sensitive manner.In'Disclosing/Apologizing for a Complication',4/11(36%)personally apologized for the complication.1/11 recognized the SP’s mistrust of the medical system.With'Breaking Bad News',27%(3/11)explored the patient’s values to identify her fatalistic beliefs.CONCLUSION:OSCEs can be used to assess deficiencies in culturally-competent care at the fellowship level.OSCEs also afford fellowships the opportunity to inform future training curricula. | Sophie Balzora Benjamin Abiri Xiao-Jing Wang James Mc Keever Michael Poles Sondra Zabar Colleen Gillespie Elizabeth Weinshel | 2015 | World Journal of Gastroenterology2015，21，6： | 2 |
| 4 | International trends in colorectal cancer incidence rates显示文摘 | Melissa MC Ahmedin J Elizabeth W | 2009 | Cancer Epidemiol Biomarkers Prev2009，18，6： | 1 |
| 5 | Pressure ulcer related pain in community populations: A prevalence survey显示文摘 | Elizabeth MC Michelle B Michelle C | 2014 | BMC Nurs2014，13，16： | 1 |
| 6 | The gene encoding the p60 subunit of chromatin assembly factor 1 (CAF1P60) maps to human chromosome 21q22,a region associated with some of the major features of Down syndrome 显示文摘 | Katsanis N Elizabeth MC | 1996 | Hum Genet1996，98，40： | 1 |
| 7 | Clinical assessment versus research methods in the assessment of suicidal behavior显示文摘 | Kevin MM Katalin S Elizabeth MC | 1995 | Am J Psychiatry1995，152，： | 1 |
| 8 | Turner' s Syndrome 显示文摘 | Virginia P Sybert Elizabeth Mc | 2004 | New- England Journal of Medicine2004，，251： | 1 |
| 9 | The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result form the rapid and prolonged activationof antigen specific CD8^+ T cells in vivo 显示文摘 | Lisa AE Elizabeth GI Julie MC | 2002 | J Immunol2002，169，： | 1 |
| 10 | The adjuvant effects of Mycobaeterium tuberculosis heat shock protein 70 result form the rapid and prolonged activation of antigen-specific CDSqT cells in vivo显示文摘 | Lisa AE Elizabeth GI Julie MC | 2002 | J Immunol2002，169，： | 1 |
| 11 | Influence of volatile and nonvolatile Fractions on intensity of Cheddar cheese flavor显示文摘 | MC GUGAN W A EMMONS D B ARMOND ELIZABETH L | 1979 | Journal of Dairy Science1979，62，3： | 1 |
| 12 | Developing Re- search Competence to Support Evidence - Based Practice 显示文摘 | Lore EB Elizabeth AS Susan MS Susan MC | 2005 | Journal of Professional Nursing2005，21，6： | 1 |
| 13 | Quantitative determination of allicin in garlic:supercritical fluid extraction and standard addition of alliin显示文摘 | Michael ER Elizabeth MC James MH | 2004 | J Agric Food Chem2004，52，： | 1 |
| 14 | The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result form the rapid and prolonged activation of an tigen-specific CD8 + T cells in vivo显示文摘 | Lisa AE Elizabeth GI Ju lie MC et at | 2002 | J Immunol2002，169，： | 1 |
| 15 | Defining and measuring quality of care: a perspective from US researchers显示文摘 | Robert B Elizabeth Mc Paul S | 2000 | International Journal for Quality in Health Care2000，12，4： | 1 |
| 16 | International trends in colorectal cancer inci- dence rates 显示文摘 | Melissa MC Ahmedin J Elizabeth W | 2009 | Cancer Epidemiol Biomarkers Prev2009，18，6： | 1 |
| 17 | Arandomized,double-blind placebo-eontrolled trial of metformin treatment of weight gain assoeiated with initiation of atypieal antipsychotic therapy in children and adolescents显示文摘 | David JK Elizabeth MC Miehael S | 2006 | Am J Psychiatry2006，163，15： | 1 |
| 18 | Quantitative deter- mination of alliein in garlic: supereritieal fluid extraction and standard addition of alliin显示文摘 | Michael ER Elizabeth MC James MH | 2004 | Agric Food Chem2004，52，： | 1 |
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