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| 1 | Inverse Gas Chromatography Used to Study Lubricating Oil Oxidation Mechanism via Changes in Kovats and Flory-Huggins Retention Parameters显示文摘Inverse gas chromatographic technique(IGC) was attempted as a new approach to follow the chem-ical changes that occur during lubricating base oil oxidation.Three groups of the oxidized base oils were pre-pared at different oxygen flow rates,periods and temperatures according to IP48method.The corrected reten-tion volumes(VR) were calculated for a series of selected test solutes possessing different functional groups onthe oxidized base oils used as stationary phases.Kovats retention index(I),Flory-Huggins interaction parame-ter(κ1∞,2),and partial molar free energy of solution(ΔGL∞),were calculated for the given test solutes fromtheirVR.The relationships between theIvalues and the oxidation variables were plotted and discussed.Theobtained results were confirmed by potentiometric titration.The study reveals that the magnitudes of variationofI,κ1∞,2orΔG∞Lretention parameters depend on the oxidation degree of the base oil.Large differences be-tween theIvalues permit discrimination between the different oxidation steps.Key words: inverse gas chromatography(IGC);oxidation;lubricating base oil;Kovats retention | MOSTAFA Nagy E EISSA Elham A | 2006 | 色谱2006，24，3： | 2 |
| 2 | Safety and efficacy of Hansenula-derived PEGylated-interferon alpha-2a and ribavirin combination in chronic hepatitis C Egyptian children显示文摘AIM:To investigate the safety and efficacy of a Hansenula-derived PEGylated(polyethylene glycol)interferon(IFN)-alpha-2a(Reiferon Retard)plus ribavirin customized regimen in treatment-na?ve and previously treated(non-responders and relapsers)Egyptian children with chronic hepatitis C infection.METHODS:Forty-six children with chronic hepatitis C virus(HCV)infection were selected from three tertiary pediatric hepatology centers.Clinical and laboratory evaluations were undertaken.Quantitative polymerase chain reaction(PCR)for HCV-RNA was performed before starting treatment,and again at 4,12,24,48,72wk during treatment and 6 mo after treatment cessation.All patients were assigned to receive a weekly subcutaneous injection of PEG-IFN-alpha-2a plus daily oral ribavirin for 12 wk.Thirty-four patients were treatment-na?ve and 12 had a previous treatment trial.Patients were then divided according to PCR results into two groups.GroupⅠincluded patients who continued treatment on a weekly basis(7-d schedule),while groupⅡincluded patients who continued treatment on a 5-d schedule.Patients from either group who were PCR-negative at week 48,but had at least one PCRpositive test during therapy,were assigned to have an extended treatment course up to 72 wk.The occurrence of adverse effects was assessed during treatment and follow up.The study was registered at www.ClinicalTrials.gov(NCT02027493).RESULTS:Only 11 out of 46(23.9%)patients showed a sustained virological response(SVR),two patients were responders at the end of treatment;however,they were lost to follow up at 6 mo post treatment.Breakthrough was seen in 18(39.1%)patients,one patient(2.17%)showed relapse and 14(30.4%)were non-responders.Male gender,short duration of infection,low viral load,mild activity,and mild fibrosis were the factors related to a better response.On the other hand,patients with high viral load and absence of fibrosis failed to respond to treatment.Before treatment,liver transaminases were elevated.After commencing treatment,they were normalized in all patients at week 4 and were maintained normal in responders till the end of treatment,while they increased again significantly in non-responders(P=0.007 and 0.003 at week 24 and 72 respectively).The 5-d schedule did not affect the response rate(1/17 had SVR).Treatment duration(whether 48 wk or extended course to 72 wk)gave similar response rates(9/36 vs 2/8 respectively;P=0.49).Type of previous treatment(short acting IFN vs PEG-IFN)did not affect the response to retreatment.On the other hand,SVR was significantly higher in previous relapsers than in previous non-responders(P=0.039).Only mild reversible adverse effects were observed and children tolerated the treatment well.CONCLUSION:Reiferon Retard plus ribavirin combined therapy was safe.Our customized regimen did not influence SVR rates.Further trials on larger numbers of patients are warranted. | Suzan El Naghi Tawhida Y Abdel-Ghaffar Hanaa El-Karaksy Elham F Abdel-Aty Mona S El-Raziky Aleef A Allam Heba Helmy Hanaa A El-Araby Behairy E Behairy Mohamed A El-Guindi Hatem El-Sebaie Aisha Y Abdel-Ghaffar Nermin A Ehsan Ahmed M El-Hennawy Mostafa M Sira | 2014 | World Journal of Gastroenterology2014，20，16： | 2 |
| 3 | Effect of spraying magnesium,boron,ascorbic acid and vitamin B complex on yield and fruit quality of Canino apricot显示文摘 | SHAHIN M F M ELHAM Z A D | 2006 | Arab Universities Journal of Agricultural Sciences2006，14，1： | 1 |
| 4 | Synthesis of new microbial pesticide metal complexes derived from cou- marin-imine ligand 显示文摘 | Amel F E Elham S A Huda M A | 2014 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy2014，128，： | 1 |
| 5 | Random mutagenesis and use of 2-deoxy-D-glucose as an antimetabolite for selection of α-amylase-overproducing mutants of AspergiUus oryzae显示文摘 | METHRDAD A ELHAM N | 2001 | World Journal of Microbiology and Biotechnology2001，17，： | 1 |
| 6 | Effect of irrigation water on growth and fruiting of Sultani fig trees in arid areas显示文摘 | EZZAT A H ABDEL M M N ELHAM A E M | 1975 | The EgyptianJournal of Agricultural Research1975，53，3： | 1 |
| 7 | Weight indexing for airfoil multi-objective optimization显示文摘 | Elham A van Tooren M J L | 2013 | Journal of Aircraft2013，50，4： | 1 |
| 8 | Medicinal uses and chemistry of flavonoid contents of some common edible tropical plants显示文摘 | MOHAMMAD A ELHAM K | 2013 | Journal of Paramedical Science2013，4，3： | 1 |
| 9 | The role of the NO/NMDA pathways in the development of morphine withdrawal induced by naloxone in vitro显示文摘 | Bichoy H Elham A Tahia T | 2005 | Pharmacol Res2005，51，4： | 1 |
| 10 | Effect of spraying magnesium, boron, ascorbic acid and vitamin B complex on yield and fruit quality of Canino apricot显示文摘 | Shahin M F M Elham Z A D | 2006 | Arab Universities Journal of Agricultural Sciences2006，14，1： | 1 |
| 11 | The role of the NO/NMDA pathways in the developmen! of morphine withdrawal induced by naloxone in vitro 显示文摘 | Biehoy H Elham A Tahia T | 2005 | Phamlacol Res2005，51，： | 1 |
| 12 | The role of the NO/NMDA pathways in the development of morphine withdrawal induced by naloxonein vitro显示文摘 | Bichoy H Elham A Tahia T | 2005 | Pharmacol Res2005，51，： | 1 |
| 13 | The role of the NO/NMDA pathways in the development of morphine withdrawal induced by naloxone in vitro显示文摘 | Bichoy H Elham A Tahia T | 2005 | Pharmacol Res2005，51，： | 1 |
| 14 | Application of geo- chemical data as evidence of water-rock interacition in the Sarvak Formation, Izeh Zone, Zagros, Iran 显示文摘 | ELHAM A M MOHAMMAD H A | 2013 | Procedia Earth and Planetary Science2013，，7： | 1 |
| 15 | Nano-particle encapsulation of fish oil by spray dr- ying显示文摘 | Seid Mahdi Jafari a Elham Assadpoor Bhesh Bhandari | 2008 | Food Research International2008，41，： | 1 |
| 16 | Interleukin-6gene polymorphism in Iranian patients with systemic lupus erythematosus显示文摘 | ESMAEIL M G ESKANDAR K S ELHAM A | 2011 | Clin Rheuma-tol2011，30，： | 1 |
| 17 | Colorimetric DNA detection of transgenic plants using gold nanoparticles functionalized with L-shaped DNA probes显示文摘 | ELHAM N AMIR M AYYOOB A | 2016 | Physica E:Low-dimensional Systems and Nanostructures2016，75，： | 1 |
| 18 | A hybrid wavelet-Kalman filter method for load forecasting显示文摘 | Tongxin Zheng Adly A Girgis Elham B Makram | 2000 | Electric Power Systems Research2000，，1： | 1 |
| 19 | A Hybrid Wavelet-Kalman Filter Method for Load Forecasting显示文摘 | Tongxin Zheng Adly A Girgis Elham B Makram | 2000 | Electric Power Systems Research2000，54，1： | 1 |
| 20 | Dispersive liquid-liquid microextraction combined with graphite furnace atomic absorption spectrometry Ultra trace determination of cadmium in water samples显示文摘 | ELHAM ZJ ARAZ B YAGHOUB A | 2007 | Anal Chim Acta2007，585，2： | 1 |
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