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| 1 | Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt显示文摘AIM: To evaluate and validate the national trends and predictors of in-patient mortality of transjugular intrahepatic portosystemic shunt(TIPS) in 15 years.METHODS: Using the National Inpatient Sample which is a part of Health Cost and Utilization Project, we identified a discharge-weighted national estimate of 83884 TIPS procedures performed in the United States from 1998 to 2012 using international classification of diseases-9 procedural code 39.1. The demographic, hospital and co-morbility data were analyzed using a multivariant analysis. Using multi-nominal logistic regression analysis, we determined predictive factors related to increases in-hospital mortality. Comorbidity measures are in accordance to the Comorbidity Software designed by the Agency for Healthcare Research and Quality.RESULTS: Overall, 12.3% of patients died during hospitalization with downward trend in-hospitalmortality with the mean length of stay of 10.8 ± 13.1 d. Notable, African American patients(OR = 1.809 vs Caucasian patients, P < 0.001), transferred patients(OR = 1.347 vs non-transferred, P < 0.001), emergency admissions(OR = 3.032 vs elective cases, P < 0.001), patients in the Northeast region(OR = 1.449 vs West, P < 0.001) had significantly higher odds of inhospital mortality. Number of diagnoses and number of procedures showed positive correlations with in-hospital death(OR = 1.249 per one increase in number of procedures). Patients diagnosed with acute respiratory failure(OR = 8.246), acute kidney failure(OR = 4.359), hepatic encephalopathy(OR = 2.217) and esophageal variceal bleeding(OR = 2.187) were at considerably higher odds of in-hospital death compared with ascites(OR = 0.136, P < 0.001). Comorbidity measures with the highest odds of in-hospital death were fluid and electrolyte disorders(OR = 2.823), coagulopathy(OR = 2.016), and lymphoma(OR = 1.842).CONCLUSION: The overall mortality of the TIPS procedure is steadily decreasing, though the length of stay has remained relatively constant. Specific patient ethnicity, location, transfer status, primary diagnosis and comorbidities correlate with increased odds of TIPS in-hospital death. | Edward Wolfgang Lee Andrew Kuei Sammy Saab Ronald W Busuttil Francisco Durazo Steven-Huy Han Mohamed M El-Kabany Justin P Mc Williams Stephen T Kee | 2016 | World Journal of Gastroenterology2016，22，25： | 7 |
| 2 | p57, structurally distinct member is a candidate tumor suppressor gene 显示文摘 | Matsuoka M Edwards MC Bai C | 1995 | Genes Der1995，9，6： | 2 |
| 3 | Fractures of the distal clavi-cle:a case for fixation显示文摘 | Edwards DJ KavanaghTG Flannery MC | 1992 | Injury1992，23，1： | 1 |
| 4 | P57kz, A structurally distinct member of the P21tip1 cdk inhibitor family, Is a candidate tumor suppressor gene 显示文摘 | Matsuoka S Edwards MC Bai C | 1995 | Gene Dev1995，9，6： | 1 |
| 5 | P57kip2, a structurally distinct member of the P21^CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene显示文摘 | Matsuoka S Edwards MC Bai C | 1995 | Genes Dev1995，9，6： | 1 |
| 6 | p57^kip1, a structurally distinct member of the p21^CIP1 Cdk inhibitor family,is a candidate tumor suppressor gene显示文摘 | Matsuoka S Edwards MC Bai C | 1995 | Genes Dev1995，9，6： | 1 |
| 7 | p57KIP2,a structurally distinct member of the p21CIP1 cdk inhibitor family,is a candidate tumor suppressor gene显示文摘 | Matsuoka S Edwards MC Bai C | 1995 | Genes Dev1995，9，6： | 1 |
| 8 | Fractures of the distal clavicle: a case for fixation显示文摘 | Edwards D J Kavanagh TG Flannery MC | 1992 | Injury1992，23，1： | 1 |
| 9 | Treatment of carcinoma of the penis the case for primary lymphadenectomy显示文摘 | Mc Dougal W Kirschner F J EDwards R | 1986 | J Urol1986，136，： | 1 |
| 10 | Effect of high tonic levels of luteinising hormone on outcome of in-vitro fertilisation显示文摘 | Howles CM Macnamee MC Edwards RG | 1986 | Lancet1986，2，8505： | 1 |
| 11 | Surgicalpathology of the ascending aorta: a clinicopathologic study of 513 cases 显示文摘 | Homme JL Aubry MC Edwards WD | 2006 | Am J Surg Pathol2006，，30： | 1 |
| 12 | The role of central mu opioid receptors in opioid-induced itch in primates 显示文摘 | Ko MC Song MS Edwards T | 2004 | J Pharmacol Exp Ther2004，310，1： | 1 |
| 13 | Fractures of the distal clavicle:a case for fixation显示文摘 | Edwards DJ Kavanagh TG Flannery MC | | 0，，01： | 1 |
| 14 | p57kip2,a structurally distinct member of the p21kip1 CDK inhibitor family,is a candicate tumor suppressor gene显示文摘 | Mutsuoka S Edwards MC Bai C | 1995 | Genes Dev1995，9，6： | 1 |
| 15 | Validation of the Australian/English version of the Diabetement Manage- ment Selfefficacy Scale 显示文摘 | Mc Dowell J Counrtney M Edward H | 2005 | Int J Nurs Practise2005，11，： | 1 |
| 16 | p57^juo2 a structurally distinct member is a candidate tumor suppressor gene显示文摘 | Matsuoka S Edwards MC Bai C | 1995 | Genes Dev1995，9，： | 1 |
| 17 | Surgical pathology of the ascending aorta: a clinicopathologic study of 513 cases 显示文摘 | Homme JL Aubry MC Edwards WD | 2006 | Am J Surg Pathol2006，30，： | 1 |
| 18 | Electron spin resonance studies of intactmammalian skeletalmuscle显示文摘 | Jackson MJ Edwards RH Symons MC | | 0，，02： | 1 |
| 19 | Chronic artery calcification is increased in patients with COPD and associated with increased morbidity and mortality 显示文摘 | Williams MC Murchison JT Edwards LD | 2014 | Thorax2014，69，8： | 1 |
| 20 | Leptin receptor expression in fetal lung increases in late gestation in the baboon:a model for human pregnancy显示文摘 | Henson MC Swan KF Edwards DE | 2004 | Reproduction2004，127，1： | 1 |
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