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| 1 | Long-term safety follow-up of children from a randomized-controlled phase Ⅱb proof-of-concept efficacy study of the live,attenuated,tetravalent dengue vaccine (CYD-TDV) in Thailand显示文摘Objective:To investigate the long-term safety of a tetravalent dengue vaccine(CYD-TDV)in children in a phase Ⅱ b follow-up study in Thailand.Methods:In the phase Ⅱb study,children aged 4-11 years were randomized(2:1)to receive three injections of CYD-TDV or serve as control at 6-month intervals,with 25 months’ active follow-up(active phase).This study was an additional four-year passive surveillance for hospitalized virologically-confirmed dengue(VCD;hospital phase).Cases of hospitalized VCD,severe hospitalized VCD,vaccine-related serious adverse events,and deaths were reported for the total population,with post-hoc analyses by enrollment age(<9 and≥9 years).Results:Of 3 997 participants receiving≥1 injection,80.1% were recruited to the hospital phase[2 131(CYD-TDV);1 072(control)].Eighty-five hospitalized VCD cases were reported in the CYD-TDV group and 46 in the control group during the four-year hospital phase[relative risk(RR):0.93,95% confidence interval(Cl):0.64-1.36].The RR over six years of follow-up was 0.77(95% CI:0.57-1.05).In those aged≥9 years,the cumulative RRs in the active phase,hospital phase,and entire six years were 0.28(95% CI:0.08-0.81),0.51(95% CI:0.25-1.05),and 0.42(95% CI:0.24-0.75),respectively.In the overall population,there were ten severe hospitalized VCD cases in the CYD-TDV group and five in the control group over six years(RR:1.00,95% CI:0.31-3.75).Conclusions:Over six years of follow-up,in children aged ≥9 years,CYD-TDV administration is associated with a reduced risk of hospitalized VCD. | Kriengsak Limkittikul Weerawan Hattasingh Danaya Chansinghakul Arunee Sabchareon Wut Dulyachai Carina Frago T Anh Wartel Edith Langevin Sophia Gailhardou Alain Bouckenooghe | 2019 | Asian Pacific Journal of Tropical Medicine2019，12，9： | 1 |
| 2 | Brand relationship quality and its value for personal contact 显示文摘 | Edith S Fred B and Maarten T | 2007 | Journal of Business Research2007，60，6： | 1 |
| 3 | Heat-shock response of Pinus and Picea seedlings显示文摘 | DAVID J G EDITH T | 1994 | Tree Physiology1994，14，1： | 1 |
| 4 | Renal rehabilitation:Obstacles,progress,and prospects for the future显示文摘 | Edith T John H | 2000 | America Journal of Kidney Diseases2000，35，4： | 1 |
| 5 | Incidental findings on integrated PET/CT that do not accumulate ^18F-FDG 显示文摘 | John F Mylene T Edith M | 2006 | AIR2006，187，： | 1 |
| 6 | Seed ferns from the late Paleozoic and Mesozoic:Any Angiosperm ancestors lurking there?显示文摘 | EDITH L T THOMAS N T | 2009 | American Journal of Botany2009，96，1： | 1 |
| 7 | Genetic analysis of the Interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease显示文摘 | Laurence T Tiphaine G Edith Lubos MD | 2005 | Circulation2005，112，： | 1 |
| 8 | Heat 2 shock response of Pinus and Picea seedling s 显示文摘 | David J Gifford Edith T | 1994 | Tree Physiology1994，，14： | 1 |
| 9 | Heat shock response of Pit,us and Picea seedlings 显示文摘 | David J Gifford Edith T | 1994 | Tree Physiology1994，，14： | 1 |
| 10 | Genetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease显示文摘 | Laurence T Tiphaine G Edith L | 2005 | Circulation2005，112，2： | 1 |
| 11 | In situ electrode modication for direct differectil a pulsc polaorgraphy of 2,6-diaminopurine and its metabolite 2, 6-diamino-8-purinol显示文摘 | Edith S Anna B T | 1983 | Anal Chim Acta1983，154，： | 1 |
| 12 | Renal rehabilitation: Obstacles, progress, and prospects for the future显示文摘 | Edith T John H | 2000 | America Journal of Kidney Diseases2000，35，1： | 1 |
| 13 | Renal rehabilitation: Obstacles, progress, and prospects for the future 显示文摘 | Edith T John H | 2000 | America Journal of Kidney Diseases2000，35，4： | 1 |
| 14 | Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction显示文摘 | Boekholdt SM Mieke T Ron JP Marc E Jolanda B Edith F | 2002 | Arterioscler Thromb Vasc Biol2002，22，12： | 1 |
| 15 | Gene therapy for restenosis 显示文摘 | Melina RK Timothy RB Edith T | 2000 | Circulation Research2000，86，： | 1 |
| 16 | Collaboration between the national tuberculosis programme and a non governmental organization in TB/HIV care at a district level:experience from Tanzania 显示文摘 | Eliud W Neema K Edith T | 2004 | African Health Sciences2004，4，2： | 1 |
| 17 | Biodegradable poly(D,L-lactic acid)-poly(ethylene glycol)-monomethyl ether diblock copolymers:structures and surface properties relevant to their use as biomaterials显示文摘 | Andrea L Jorg T Edith S | 2000 | Biomaterials2000，21，： | 1 |
| 18 | Heat-shock response of Pinus and Picea seedlings 显示文摘 | David J Gifford Edith T | 1994 | Tree Physiology1994，14，： | 1 |
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