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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Exploiting the diversity of tomato:the development of a phenotypically and genetically detailed germplasm collection显示文摘A collection of 163 accessions,including Solanum pimpinellifolium,Solanum lycopersicum var.cerasiforme and Solanum lycopersicum var.lycopersicum,was selected to represent the genetic and morphological variability of tomato at its centers of origin and domestication:Andean regions of Peru and Ecuador and Mesoamerica.The collection is enriched with S.lycopersicum var.cerasiforme from the Amazonian region that has not been analyzed previously nor used extensively.The collection has been morphologically characterized showing diversity for fruit,flower and vegetative traits.Their genomes were sequenced in the Varitome project and are publicly available(solgenomics.net/projects/varitome).The identified SNPs have been annotated with respect to their impact and a total number of 37,974 out of 19,364,146 SNPs have been described as high impact by the SnpEeff analysis.GWAS has shown associations for different traits,demonstrating the potential of this collection for this kind of analysis.We have not only identified known QTLs and genes,but also new regions associated with traits such as fruit color,number of flowers per inflorescence or inflorescence architecture.To speed up and facilitate the use of this information,F2 populations were constructed by crossing the whole collection with three different parents.This F2 collection is useful for testing SNPs identified by GWAs,selection sweeps or any other candidate gene.All data is available on Solanaceae Genomics Network and the accession and F2 seeds are freely available at COMAV and at TGRC genebanks.All these resources together make this collection a good candidate for genetic studies. | Estefanía Mata-Nicolás Javier Montero-Pau Esther Gimeno-Paez Víctor Garcia-Carpintero Peio Ziarsolo Naama Menda Lukas A.Mueller JoséBlanca Joaquín Cañizares Esther van der Knaap María JoséDíez | 2020 | Horticulture Research2020，7，1： | 2 |
| 3 | Diagnostic value of N-terminal pro- brain natriuretic peptide in pleura] effusions of cardiac origin 显示文摘 | Luis V Esther SJ Antonio P | 2011 | Arch Bronconeumol2011，47，5： | 1 |
| 4 | TRAIL enhances efficacy of radiotherapyin a p53 mutant, Bcl-2 overexpressing lymphoid malignancy显示文摘 | Esther HJW Inge V Stefan R | 2006 | Radiotherapy and Oncology2006，80，2： | 1 |
| 5 | In Vitro Antioxidant and Anti-rhizopus Activities of Lamiaceae Herbal Extracts显示文摘 | Víctor López Silvia Akerreta Esther Casanova Jose María García-Mina Rita Yolanda Cavero María Isabel Calvo | 2007 | Plant Foods for Human Nutrition2007，，4： | 1 |
| 6 | Biliary complications after liver transplantation:diagnosis with MR cholangiopancreatography显示文摘 | Carlos V Esther A Magali C | 2005 | AJR2005，184，3： | 1 |
| 7 | A simple and rapid HPLC- MS method for the simultaneous determination of epinephrine, norepinephrine,dopamine and 5-hydroxytryptamine Application to the seeretion of bovine ehromaffin cell cultures显示文摘 | Victoria C Esther S Eugenio V | 2007 | Journal of Chromatography B2007，847，2： | 1 |
| 8 | Of saints and sinners:How ap- 'peals to collective pride and guilt affect outgroup helping显示文摘 | Esther V L Wilco V D Umit K | 2013 | Group Processes Intergroup Relations2013，16，6： | 1 |
| 9 | Biliary complications after liver transplantation: diagnosis with MR cholangiopancreatography显示文摘 | Carlos V Esther A Magali C | 2005 | AJR2005，184，3： | 1 |
| 10 | Potent inhibition of human phosphodiesterase-5 by icariin derivatives 显示文摘 | Dell 'Agli Mario Galli Germana V Dal Cero Esther | 2008 | J Nat Prod ( NP)2008，71，9： | 1 |
| 11 | Combined oral benzo pyrene and inhalatory ozone exposure have no effect on lung tumor development in DNA repair-deficient Xpa mice显示文摘 | ESTHER M H ANNEMIEKE D V RUDOLF B B | 2003 | Carcinogenesis2003，24，3： | 1 |
| 12 | Selective dehydrolinalool hydrogenation with poly(ethylene oxide)- block -poly-2-vinylpyridine micelles filled with Pd nanoparticles显示文摘 | Natalia V Semagina Alexei V Bykov Esther M Sulman Valentina G Matveeva Stanislav N Sidorov Lidia V Dubrovina Peter M Valetsky Olga I Kiselyova Alexei R Khokhlov Barry Stein Lyudmila M Bronstein | 2003 | Journal of Molecular Catalysis A Chemical2003，，1： | 1 |
| 13 | A subclass of tumor-inhibitory monoclonal antibody to HER-2/Neu/HER2 blocks crosstalk with growth factor receptors显示文摘 | Lean N K Nora V Esther H | 1997 | Oncogene1997，14，7： | 1 |
| 14 | Influence of clarithromycin on early atherosclerotic lesions after chlamydia pneumoniae infection in a rabbit model显示文摘 | Ignatius W Fong BC Esther V | 2002 | Antimicrobial Agents and Chemotherapy2002，46，8： | 1 |
| 15 | Posterior reversible encephalopathy syndrome: a truly treatable neurologic ill- ness显示文摘 | Esther V Hobson I Craven S | 2012 | Periton Dial Int2012，32，6： | 1 |
| 16 | An Adaptive Color-Based Particle Filter显示文摘 | Katja N Esther K M Lue V G | 2003 | Image Vision Computing2003，21，1： | 1 |
| 17 | An adaptive color - based particle filter 显示文摘 | KATJA N ESTHER K M LUC V G | 2003 | Image and Vision Computing2003，21，1： | 1 |
| 18 | Multidrug - resistant Acineto- baeter baumannii harboring OXA - 24 carbapenemase, Spain 显示文摘 | Joshi A Maria M Esther V | 2011 | Emerg Infect Dis2011，17，6： | 1 |
| 19 | Reactome:a knowledge base of biologic pathways and processes显示文摘 | Imre V Peter D Esther S | 2007 | Genome Biology2007，8，3： | 1 |
| 20 | Modelling of the acid hydrolysis of potato (Solanum tuberosum) for fermentative purposes显示文摘 | Esther G R Oscar M R Manuel V | 2012 | Biomass and Bioenergy2012，42，： | 1 |
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