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| 1 | 冠状动脉血流缓慢的患者其血浆可溶性黏附分子ICAM-1、VCAM-1和E-选择素水平升高显示文摘Background: Inflammation has been reported to be a major contributing factor to many cardiovascular events. In the present study, we aimed to evaluate plasma soluble adhesion molecules; intercellular adhesion molecule-1(ICAM-1), vascular cell adhesion molecule-1(VCAM-1) and E-selectin as possible indicators of endothelial activation or inflammation in patients with slow coronary flow. Method: Study population included 17 patients with angiographically proven normal coronary arteries and slow coronary flow in all three coronary vessels(group I, 11 male, 6 female, mean age=48± 9 years), and 20 subjects with angiographically proven normal coronary arteries without associated slow coronary flow(group II, 11 male, 9 female, mean age=50± 8 years). Coronary flow rates of all patients and control subjects were documented by Thrombolysis In Myocardial Infarction frame count(TIMI frame count). All patients in group I had TIMI frame counts greater than two standard deviation above those of control subjects(group II) and, therefore, were accepted as exhibiting slow coronary flow. Serum levels of ICAM-1, VCAM-1, and E-selectin were measured in all patients and control subjects using commercially available ELISA kits. Results: Serum ICAM-1, VCAM-1, and E-selectin levels of patients with slow coronary flow were found to be significantly higher than those of control subjects with normal coronary flow(ICAM-1: 545± 198 ng/ml vs. 242± 113 ng/ml respectively, p< 0.001, VCAM-1: 2040± 634 ng/ml vs. 918± 336 ng/ml respectively, p< 0.001, E-selectin: 67± 9 ng/ml vs. 52± 8 ng/ml respectively, p< 0.001). Average TIMI frame count was detected to be significantly correlated with plasma soluble ICAM-1(r=0.550, p< 0.001), VCAM-1(r=0.569, p< 0.001) and E-selectin(r=0.443, p=0.006). Conclusion: Increased levels of soluble adhesion molecules in patients with slow coronary flow may be an indicator of endothelial activation and inflammation and are likely to be in the causal pathway leading to slow coronary flow. | Turhan H. Saydam G. S. Erbay A. R. 杜媛(译) 孙凯(校) | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006,2,8: | 6 |
| 2 | Precontoured buttress plate vs reconstruction plate for acetabulum posterior wall fractures: A biomechanical study显示文摘BACKGROUND The purpose of open reduction and internal fixation of acetabulum posterior wall fractures is to restore anatomical structure and stability of the hip joint, in order to start weight bearing as soon as possible and prevent hip arthrosis; restoration of the anatomy should preserve function of the joint as well. Although 'special shaped precontoured plates' have been developed in recent years for surgical treatment of this region, studies comparing the traditional plates with the newly designed precontoured plates are lacking.AIM To evaluate the biomechanical properties of precontoured anatomic buttress and conventional curved reconstruction plates(CCRPs) for posterior wall acetabulum fracture treatment.METHODS Twelve pelvis models were created for testing plate treatment of fracture in the posterior wall of the acetabulum. These 12 pelvis models were used to create 24 hemipelvis models(experimental) by cutting from the sagittal plane and passing over the center of gravity, after which the posterior wall acetabular fractures(of similar type and size) were created. In these experimental models, the right acetabulum was fixed with a 5-hole CCRP, while the left was fixed with a precontoured anatomic buttress plate(PABP). Samples were placed through thetest device and were subjected to static load testing, with a constant testing velocity of 2 mm/min until the load reached 2.3 kN or the acetabular fixation failed. Dynamic tests were also performed with sinusoidal wave load, with a maximal load of 2.3 kN and a load ratio of 0.1.RESULTS The average stiffness values were 460.83 ± 95.47 N/mm for the PABP and 291.99± 118.58 N/mm for the 5-hole CCRP. The precontoured anatomic acetabulum buttress plates had significantly higher rigidity than the CCRPs(P = 0.022). There was a statistically significant difference between the unloaded and 2.3 kN-loaded values of AL(posterosuperior fracture line vertical to the ground surface) and CL(posteroinferior fracture line vertical to the ground surface) parameters for both the PABPs and the 5-hole CCRPs(P = 0.036 and P = 0.045, respectively).According to the static tests, the amount of total displacement was significantly less in the PABPs than in the CCRPs. Comparative analysis of the displacement in the BL(posterior wall fracture line horizontal to the ground) parameter yielded no statistically significant differences between the PABP and the 5-hole CCRPs(P= 0.261).CONCLUSION PABP provides more stable fixation in acetabulum posterior wall fractures than5-hole CCRP, allowing for proximal or distal fracture line screw application without reshaping. | Güray Altun Gürsel Saka Teyfik Demir Fatma Kübra Erbay Elibol Mehmet Or?un Polat | 2019 | World Journal of Orthopedics2019,10,5: | 3 |
| 3 | Levels of soluble adhesion molecules in various clinical presentations of coronary atherosclerosis 显示文摘 | Guray U Erbay AR Guray Y | 2004 | Int J Cardiol2004,96,: | 1 |
| 4 | Meralgia paresthetica in diferential diagnosis of Low - back pain 显示文摘 | Erbay H | 2002 | The clinical journal of pain2002,18,2: | 1 |
| 5 | Risk factors for in-hospital mortality in infective endocarditis:five years′ experience at a tertiary care hospital in Turkey显示文摘 | Erbay AR Erbay A Canga A | | 0,,02: | 1 |
| 6 | Is There Any Relation Between Pseudoexfoliation Syndrome and Alzheimer’s Type Dementia?*显示文摘 | Tongabay Cumurcu Ferhat Dorak Birgul Elbozan Cumurcu Lale Gonenir Erbay Ercan Ozsoy | 2013 | Seminars in Ophthalmology2013,,4: | 1 |
| 7 | Living donor liver transplantation in adults: vascular variants important in surgical planning for donors and recipients显示文摘 | Erbay N Raptopoulos V Pomfret EA | 2003 | AJR Am J Roentgenol2003,181,1: | 1 |
| 8 | Nutrient sensing and inflamma-tion in metabolic diseases 显示文摘 | Hotamisligil GS Erbay E | 2008 | Nat Rev Immunol2008,8,12: | 1 |
| 9 | Nerve atrophy in severe trigeminal neuralgia: noninvasive confirmation at MR imaging--initial experience显示文摘 | Erbay SH Bhadelia RA O'Callaghan M | 2006 | Radiology2006,238,: | 1 |
| 10 | Meralgia paresthetica in differential diagnosis of Low - back pain显示文摘 | Erbay H | 2002 | The clinical journal of pain2002,18,2: | 1 |
| 11 | Decreased platelet activation and endothelial dysfunction after percutaneous mitral balloon valvuloplasty显示文摘 | Yetkin E Erbay AR Tuthan H | 2003 | International Journal of Cardiology2003,91,23: | 1 |
| 12 | Headache response to nitrate in patients with coronary artery disease and systolic heart failure显示文摘 | Sivri N Tekin G Erbay AR | 2012 | Int J Cardiol2012,158,3: | 1 |
| 13 | Levels of souble adhesion molecular in various clinical presentationation of coronary atherosclerosis 显示文摘 | Guray U Erbay AR Gury Y | 2004 | Int J Cardio12004,96,2: | 1 |
| 14 | Levels of circulating adhesion molecules in rheumatic mitral stenosis显示文摘 | Yetkin E Erbay AR Ileri M | 2001 | Am J Cardiol2001,88,10: | 1 |
| 15 | Knowledge Levels Regarding Crimean-Congo Hemorrhagic Fever Among Emergency Healthcare Workers in an Endemic Region显示文摘 | Sadiye Yolcu Cigdem Kader Afsin Emre Kayipmaz Sedat Ozbay Ayse Erbay | 2014 | Journal of Clinical Medicine Research2014,,3: | 1 |
| 16 | Evaluation of risk factors for mortality in intensive care units:A propective study from a referral hospital in Turkey显示文摘 | Colpan A Akinci E Erbay A | 2005 | Am J Infect Control2005,33,1: | 1 |
| 17 | A genetic variant at the fatty acid- binding protein aP2 locus reduces the risk for hypertr/glyceridemia, type 2 diabetes, and cardiovascular disease 显示文摘 | Tuneman G Erbay E Hom X | 2006 | Proc Natl Acad Sci USA2006,103,18: | 1 |
| 18 | Evaluation of antibiotic use in intensive care units of tertiary care hospital in Turkey显示文摘 | Erbay A Bodur H Akinici E | 2005 | J Hosp Infect2005,59,1: | 1 |
| 19 | Case report: hypo-glycemia and diffusion-weighted imaging 显示文摘 | Chan R Erbay S Oljeski S | 2003 | J ComputAssist Toraogr2003,27,3: | 1 |
| 20 | Association between neurovascular contact on MRI and response to gamma knife radiosurgery in trigeminal neuralgia显示文摘 | ERBAY S H BHADELIA R A RIESENBURGER R | 2006 | Neuroradiology2006,48,1: | 1 |