|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond. | Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg | 2018 | Horticulture Research2018，5，1： | 10 |
| 2 | Apple whole genome sequences:recent advances and new prospects显示文摘In 2010,a major scientific milestone was achieved for tree fruit crops:publication of the first draft whole genome sequence(WGS)for apple(Malus domestica).This WGS,v1.0,was valuable as the initial reference for sequence information,fine mapping,gene discovery,variant discovery,and tool development.A new,high quality apple WGS,GDDH13 v1.1,was released in 2017 and now serves as the reference genome for apple.Over the past decade,these apple WGSs have had an enormous impact on our understanding of apple biological functioning,trait physiology and inheritance,leading to practical applications for improving this highly valued crop.Causal gene identities for phenotypes of fundamental and practical interest can today be discovered much more rapidly.Genome-wide polymorphisms at high genetic resolution are screened efficiently over hundreds to thousands of individuals with new insights into genetic relationships and pedigrees.High-density genetic maps are constructed efficiently and quantitative trait loci for valuable traits are readily associated with positional candidate genes and/or converted into diagnostic tests for breeders.We understand the species,geographical,and genomic origins of domesticated apple more precisely,as well as its relationship to wild relatives.The WGS has turbo-charged application of these classical research steps to crop improvement and drives innovative methods to achieve more durable,environmentally sound,productive,and consumer-desirable apple production.This review includes examples of basic and practical breakthroughs and challenges in using the apple WGSs.Recommendations for“what’s next”focus on necessary upgrades to the genome sequence data pool,as well as for use of the data,to reach new frontiers in genomics-based scientific understanding of apple. | Cameron P.Peace Luca Bianco Michela Troggio Eric van de Weg Nicholas P.Howard Amandine Cornille Charles-Eric Durel Sean Myles ZoëMigicovsky Robert J.Schaffer Evelyne Costes Gennaro Fazio Hisayo Yamane Steve van Nocker Chris Gottschalk Fabrizio Costa David Chagné Xinzhong Zhang Andrea Patocchi Susan E.Gardiner Craig Hardner Satish Kumar Francois Laurens Etienne Bucher Dorrie Main Sook Jung Stijn Vanderzande | 2019 | Horticulture Research2019，6，1： | 3 |
| 3 | Mapping of qualitative and quantitative phenotypic traits in Rosa using AFIP markers显示文摘 | Crespel L Chirollet M Durel C E | 2002 | Theor Appl Genet2002，105，： | 1 |
| 4 | Experimental autoimmuneence phalitis and inflammation in the absence of interleukin-12显示文摘 | Bercher B Durell BG Noelle RJ | 2002 | J Clin Invest2002，110，4： | 1 |
| 5 | Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12显示文摘 | Becher B Durell BG Noelle RJ | 2002 | J Clin Invest2002，110，： | 1 |
| 6 | Genome mapping of three major resistance genes to woolly apple aphid (Eriosoma lanigerum Hausm.)显示文摘 | V. G. M. Bus D. Chagné H. C. M. Bassett D. Bowatte F. Calenge J.-M. Celton C.-E. Durel M. T. Malone A. Patocchi A. C. Ranatunga E. H. A. Rikkerink D. S. Tustin J. Zhou S. E. Gardiner | 2008 | Tree Genetics & Genomes2008，，2： | 1 |
| 7 | Congenital cystic lesions of the lung显示文摘 | Durell J Lakhoo K | 2014 | Early Hum Dev2014，90，： | 1 |
| 8 | Atomoxetine treatment of attention-deficit/hyperactivity disorder in young adults with as- sessment of functional outcomes: a randomized, double-blind, pla- cebo-controlled clinical trial 显示文摘 | Durell TM Adler LA Williams DW | 2013 | J Clin Psychophannacol2013，33，1： | 1 |
| 9 | Gamma delta T cell - deficient mice have a down- regulated CD8 + t cell immune response against Encephalitozoon cuniculi infection显示文摘 | Moretto M Durell B Schwartzman JD | 2001 | Junl52001，166，12： | 1 |
| 10 | Development of a substrate-based cyclic phosphopeptide inhibitor of protein phosphatase 2C delta, Wipl 显示文摘 | Yamaguchi H Durell SR Feng H | 2006 | Biochemistry2006，45，13： | 1 |
| 11 | Experimental autoimmune ence-phalitis and inflammation in the absence of interleukin-12显示文摘 | Becher B Durell BG Noelle RJ | 2002 | J Clin Invest2002，110，： | 1 |
| 12 | Minimally invasive video-assisted thyroidectomy for treatment of benign solitary thyroid nodules in pediatric patients显示文摘 | Durel J Kluka E Walvekar RR | | 0，，： | 1 |
| 13 | Plant responses to cellular dehydration during environment stress显示文摘 | Durel | 1993 | Plant Physiology1993，103，10： | 1 |
| 14 | Structural Models of the KtrB, TrkH,and Trk! ,2 Symporters Based on the Structure of the KcsA K + Channel显示文摘 | Durell S R Guy H R | 1999 | Biophysical Journal1999，77，2： | 1 |
| 15 | Hepcidin targets ferroportin for degradation in hepatocytes 显示文摘 | Ramey G Deschemin JC Durel B | 2010 | Haematologica2010，95，3： | 1 |
| 16 | Iron overload in Hepcl (-/-) mice is not impairing glucose homeostasis显示文摘 | Ramey G Faye A Durel B | 2007 | FEBS Lett2007，581，5： | 1 |
| 17 | Hepcidin targets ferroportin for degradation in hepatocytes显示文摘 | Ramey G Deschemin JC Durel B | 2010 | Haematologica2010，95，： | 1 |
| 18 | Genomic mapping in Pinus pinaster( matitime pine) using RAPD and protein markers 显示文摘 | Plomion C BahIman N Durel C E | 1995 | Heredity1995，74，： | 1 |
| 19 | Genome mapping of three major resistance genes to woolly apple aphid (Eriosoma lanigerum Hausm.)显示文摘 | V. G. M. Bus D. Chagné H. C. M. Bassett D. Bowatte F. Calenge J.-M. Celton C.-E. Durel M. T. Malone A. Patocchi A. C. Ranatunga E. H. A. Rikkerink D. S. Tustin J. Zhou S. E. Gardiner | 2008 | Tree Genetics & Genomes2008，，2： | 1 |
| 20 | Relating molecular flex-ibility to function:a case study of tubulin显示文摘 | Keskin 0 Durell S R Bahar I | 2002 | Biophys J2002，83，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员