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| 1 | Acute alcoholic hepatitis, end stage alcoholic liver disease and liver transplantation: An Italian position statement显示文摘Alcoholic liver disease encompasses a broad spectrum of diseases ranging from steatosis steatohepatitis,fibrosis,and cirrhosis to hepatocellular carcinoma.Forty-four per cent of all deaths from cirrhosis are attributed to alcohol.Alcoholic liver disease is the second most common diagnosis among patients undergoing liver transplantation(LT).The vast majority of transplant programmes(85%)require 6 mo of abstinence prior to transplantation;commonly referred to as the'6-mo rule'.Both in the case of progressive end-stage liver disease(ESLD)and in the case of severe acute alcoholic hepatitis(AAH),not responding to medical therapy,there is a lack of evidence to support a 6-mo sobriety period.It is necessary to identify other risk factors that could be associated with the resumption of alcohol drinking.The'Group of Italian Regions'suggests that:in a case of ESLD with model for end-stage liver disease<19 a 6-mo abstinence period is required;in a case of ESLD,a 3-mo sober period before LT may be more ideal than a 6-mo period,in selected patients;and in a case of severe AAH,not respond-ing to medical therapies(up to 70%of patients die within 6 mo),LT is mandatory,even without achieving abstinence.The multidisciplinary transplant team must include an addiction specialist/hepato-alcohologist.Patients have to participate in self-help groups. | Gianni Testino Patrizia Burra Ferruccio Bonino Francesco Piani Alessandro Sumberaz Roberto Peressutti Andrea Giannelli Castiglione Valentino Patussi Tiziana Fanucchi Ornella Ancarani Giovanna De Cerce Anna Teresa Iannini Giovanni Greco Antonio Mosti Marilena Durante Paola Babocci Mariano Quartini Davide Mioni Sarino Aricò Aniello Baselice Silvia Leone Fabiola Lozer Emanuele Scafato Paolo Borro | 2014 | World Journal of Gastroenterology2014，20，40： | 5 |
| 2 | Urogenital schistosomiasis and soiltransmitted helminthiasis(STH)in Cameroon:An epidemiological update at Barombi Mbo and Barombi Kotto crater lakes assessing prospects for intensified control interventions显示文摘Background:The crater lakes of Barombi Mbo and Barombi Kotto are well-known transmission foci of schistosomiasis and soil-transmitted helminthiasis having had several important control initiatives previously.To collect contemporary epidemiological information,a cross-sectional survey was undertaken inclusive of:signs and symptoms of disease,individual treatment histories,local water,sanitation and hygiene(WASH)-related factors and malacological surveillance,with molecular characterisation of specimens.Methods:At each lake,a community cross-sectional survey was undertaken using a combination of stool and urine parasitological sampling,and interview with pro-forma questionnaires.A total of 338 children and adults participated.Material from snail and parasite species were characterised by DNA methods.Results:Egg-patent prevalence of urogenital schistosomiasis was 8.7%at Barombi Mbo(all light-intensity infections)and 40.1%at Barombi Kotto(21.2%heavy-intensity infections).Intestinal schistosomiasis was absent.At Barombi Kotto,significantly more women reported signs and symptoms associated with female genital schistosomiasis.While there had been extensive recent improvement in WASH-related infrastructure at Barombi Mbo,water contact risk scores were higher among schistosomiasis-infected participants(P<0.001)and at Barombi Kotto in general(P<0.001).Across both lakes,mean prevalence of STH was very low(6.3%)evidencing an impressive decrease of 79.0%over the last decade;neither Strongyloides stercoralis nor Ascaris lumbricoides were found.A total of 29 freshwater sampling sites were inspected for snails,13 in Barombi Mbo and 16 in Barombi Kotto;water chemistry differed significantly(P<0.0001)between lakes for both mean pH(7.9 v.9.6)and mean conductivity(64.3μS v.202.1μS)respectively.Only two Bulinus camerunensis found on the central island of Barombi Kotto were observed to shed schistosome cercariae,but schistosome DNA was later detected in Bulinus sampled from both lakes as well as in Indoplanorbis exustus,an invasive species from Asia.Conclusions:STH is currently at very low levels while urogenital schistosomiasis is of greatest concern at Barombi Kotto.This assessment highlights a unique opportunity for further study of the epidemiological dynamics at these crater lakes,to evaluate future intensified interventions both in terms of gaining and sustaining control at Barombi Kotto or in moving towards local interruption of transmission of both diseases at Barombi Mbo. | Suzy J.Campbell J.Russell Stothard Faye O’Halloran Deborah Sankey Timothy Durant Dieudonne Eloundou Ombede Gwladys Djomkam Chuinteu Bonnie LWebster Lucas Cunningham EJames LaCourse Louis-Albert Tchuem-Tchuente | 2017 | Infectious Diseases of Poverty2017，6，1： | 4 |
| 3 | 用FPGA实现安全处理显示文摘数据加密领域的形势看起来已与2001年初期大不相同,那时许多厂商都放弃了网络安全芯片市场。有许多新成立的公司以及著名厂商都在扩展其安全产品。2001年下半年连续发生的两个事件改变了网络安全的发展前景。在2001年夏天,红色代码和SirCam类的蠕虫和病毒不仅侵入了美国企业的网络,甚至还进入了原来被认为安全的政府服务器。突然之间。 | Amit Dhir Graeme Durant | 2003 | 世界产品与技术2003，，6： | 3 |
| 4 | State of the art biological therapies in pancreatic cancer显示文摘Pancreatic ductal adenocarcinoma(PDAC) is one of the most lethal malignancies with a five-year survival rate of approximately 5%. Several target agents have been tested in PDAC, but almost all have failed to demonstrate efficacy in late phase clinical trials, despite the better understanding of PDAC molecular biology generated by large cancer sequencing initiatives in the past decade. Eroltinib(a small-molecule tyrosine-kinase inhibitor of epidermal growth factor receptor) plus gemcitabine is the only schedule with a biological agent approved for advanced pancreatic cancer, but it has resulted in a very modest survival benefit in unselected patients. In our work, we report a summary of the main clinical trials(closed and ongoing) that refer to biological therapy evaluation in pancreatic cancer treatment. | mariacristina di marco elisa grassi sandra durante silvia vecchiarelli andrea palloni marina macchini riccardo casadei claudio ricci riccardo panzacchi donatella santini guido biasco | 2016 | World Journal of Gastrointestinal Oncology2016，8，1： | 3 |
| 5 | 彻底去除制革废水中难处理组分铬的研究显示文摘本文采用电化学法对意大利阿孜南诺制革中心净化厂4×104m3.d-1的废水进行Cr(III)去除的研究。我们主要考察Cr(III)去除率与减少有机碳总量(TOC)和减少化学需氧量(COD)之间的关系。在这里我们给出了去除Cr(III)的不同方法的研究结果。其中,包括适用于单独使用或耦合使用的高级氧化技术(AOPs)和电凝法。当单独应用这些方法进行处理时,所得到的结果都不能令人满意。尤其是,由于形成的Cr(VI)比Cr(III)更容易溶解,高级氧化技术(AOPs)完全低效。我们通过结合臭氧氧化和电凝法实现了Cr(III)的高效率去除,去除率高达99.7%。这个结果与通过形成NH4Fe(CrO4)2进行快速沉淀的方式去除铬(六价铬形式)的结果是一致的。 | Christian Durante Abdirisak Ahmed Isse Giancarlo Sandonà 王笃政 | 2012 | 西部皮革2012，，12： | 2 |
| 6 | Lessons from French national guidelines on the treatment of venous thrombosis and central venous catheter thrombosis in cancer patients显示文摘 | Dominique Farge Cecile Durant Stéphane Villiers Anne Long Alfred Mahr Michel Marty Philippe Debourdeau | 2010 | Thrombosis Research2010，，： | 2 |
| 7 | Towards interruption of schistosomiasis transmission in sub-Saharan Africa:developing an appropriate environmental surveillance framework to guide and to support‘end game’interventions显示文摘Schistosomiasis is a waterborne parasitic disease in sub-Saharan Africa,particularly common in rural populations living in impoverished conditions.With the scale-up of preventive chemotherapy,national campaigns will transition from morbidity-to transmission-focused interventions thus formal investigation of actual or expected declines in environmental transmission is needed as‘end game’scenarios arise.Surprisingly,there are no international or national guidelines to do so in sub-Saharan Africa.Our article therefore provides an introduction to key practicalities and pitfalls in the development of an appropriate environmental surveillance framework.In this context,we discuss how strategies need to be adapted and tailored to the local level to better guide and support future interventions through this transition.As detection of egg-patent infection in people becomes rare,careful sampling of schistosome larvae in freshwater and in aquatic snails with robust species-specific DNA assays will be required.Appropriate metrics,derived from observed prevalence(s)as compared with predetermined thresholds,could each provide a clearer insight into contamination-and exposure-related dynamics.Application could be twofold,first to certify areas currently free from schistosomiasis transmission or second to red-flag recalcitrant locations where extra effort or alternative interventions are needed. | J.Russell Stothard Suzy J.Campbell Mike Y.Osei-Atweneboana Timothy Durant Michelle C.Stanton Nana-Kwadwo Biritwum David Rollinson Dieudonne R.Eloundou Ombede Louis-Albert Tchuem-Tchuente | 2017 | Infectious Diseases of Poverty2017，6，1： | 2 |
| 8 | Pharmacokinetic parameters and killing rates in serum of volunteers receiving amoxicillin,cefadroxil or cefixime alone or associated with niflumic acid or paracetamol 显示文摘 | Carsenti-Etesse H Farinotti R Durant J | 1998 | Eur J Drug Metab Pharmacokinet1998，23，： | 2 |
| 9 | Natural orifice surgery: initial US experience utilizing the StomaphyXTM device to reduce gastric pouches after Roux-en-Y gastric bypass显示文摘 | Dean Mikami Bradley Needleman Vimal Narula Janice Durant W. Scott Melvin | 2010 | Surgical Endoscopy2010，，1： | 2 |
| 10 | The challenges on operating a zero net energy building facing global warming conditions显示文摘This study proposes a methodology to evaluate the energy performance of existing Zero Energy Buildings and to prospect retrofit strategies in a Savannah climate,concerning the A2 scenario of emissions from the Fourth Report of the Intergovernmental Panel on Climate Change.The selected building to study is recognized for its high energy performance,named Centro SEBRAE de Sustentabilidade(CSS).Two efficient measures were considered:(i)improvement in the air conditioning system coefficient of performance(COP)and(ii)in the energy efficiency of the photovoltaic plates of generation on-site.The methodology is grounded in the potential bioclimatic concept and the employed steps applied were:preparation of climate archives in the 2020,2050 and 2080 time-slices;calibration of the computational model;evaluation of the retrofit strategies on its energy consumption efficiency through computer simulation.Considering the CSS has already attended mostly the bioclimatic strategies for the local climate and has high efficiency measures in its systems,the retrofit focused the air conditioning and PV system.The isolated retrofit of the air conditioning system was unable to guarantees the NZEB condition despite providing an adequate level of energy efficiency until 2080.The retrofit of the PV system was the only one that provides the NZEB condition for climate change scenarios.The contribution of this paper is to provide a guide to be used in NZEBs,with measures of optimization that provide high potential bioclimatic face to the local where it is built,making it possible to maintain this condition in scenarios of global warming. | Alberto Hernandez Neto Luciane Cleonice Durante Ivan Julio Apolonio Callejas Emeli Lalesca Aparecida da Guarda JoséVinnicius Ranieri Moreira | 2022 | Building Simulation2022，15，3： | 2 |
| 11 | Heme oxygenase-1 attenuates vascular remodeling following balloon injury in rat carotid arteries显示文摘 | Tulis DA Durante W Peyton KJ | 2001 | Atherosclerosis2001，155，1： | 1 |
| 12 | Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation显示文摘 | Tulis DA Durante W Liu X | 2001 | Circulation2001，104，22： | 1 |
| 13 | Carbon monoxide and vascular cell function显示文摘 | Durante W Schafer AI | 1998 | Int J Mol Med1998，2，： | 1 |
| 14 | High-dose chemotherapy in small-cell lung cancer显示文摘 | Pasini F Durante E De Manzoni D er al | 2002 | Anticancer Res2002，22，6： | 1 |
| 15 | Effect of transcription factor GATA-2 on phagocytic activity of alveolar macrophages from Pneumocystis carinii-infected hosts显示文摘 | Lasbury ME Tang X Durant PJ Lee CH | 2003 | Infect Immun2003，71，9： | 1 |
| 16 | Suxamethonium显示文摘 | Durant NN Katz RL | 1982 | Br J Anaesth1982，54，： | 1 |
| 17 | Observations on Physical Activity in Physical Locations:Age,Gender,Ethnicity,and Month Effects显示文摘 | Baranowski Tom Thompson W O Durant R H | 1993 | Research Quarterly for Exercise and Sport1993，64，2： | 1 |
| 18 | Pioglitazone attenuates the detrimental effects of advanced glycation end-products in the pancreatic beta cell line HIT-T15显示文摘 | Puddu A Sanguineti R Durante A | 2012 | Regul Pept2012，177，13： | 1 |
| 19 | BRAF Mutations in papillary thyroid carcinomas inhibit genes involved in iodine metabolism 显示文摘 | Durante C Puxeddu E Feretti E | 2007 | J Clin Endocrinol Metab2007，92，7： | 1 |
| 20 | Identification of candidates for a subunit vaccine against extraintestinal pathogenic Escherichia coli 显示文摘 | Durant L Metais A Soulama-Mouze C | 2007 | Infect Immun2007，75，4： | 1 |
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