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13篇 您的检索式:作者名="Duarte LE"
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1African origins and chronic kidney disease susceptibility in the human immunodeficiency virus era显示文摘Chronic kidney disease(CKD) is a major public health problem worldwide with the estimated incidence growing by approximately 6% annually. There are striking ethnic differences in the prevalence of CKD such that, in the United States, African Americans have the highest prevalence of CKD, four times the incidence of end stage renal disease when compared to Americans of European ancestry suggestive of genetic predisposition. Diabetes mel itus, hypertension and human immunodeficiency virus(HIV) infection are the major causes of CKD. HIV-associated nephropathy(HIVAN) is an irreversible form of CKD with considerable morbidity and mortality and is present predominantly in people of African ancestry. The APOL1 G1 and G2 alleles were more strongly associated with the risk for CKD than the previously examined MYH9 E1 risk haplotype in individuals of African ancestry. A strong association was reported in HIVAN, suggesting that 50% of African Americans with two APOL1 risk alleles, if untreated, would develop HIVAN. However these two variants are not enough to cause disease. The prevailing belief is that modifying factors or second hits(including genetic hits) underlie the pathogenesis of kidney disease. This work reviews the history of genetic susceptibility of CKD and outlines current theories regarding the role for APOL1 in CKD in the HIV era.Alex N Kasembeli Raquel Duarte Michèle Ramsay Saraladevi Naicker 2015World Journal of Nephrology2015,4,2:3
2Thoracolumbar imbal- ance analysis for osteotomy planification using a new method : FBI technique 显示文摘Le H Leijssen P Duarte M 2011Eur Spine J2011,20,5:1
3Thoracolumbar imbalanceanalysis for osteotomy planification using a new method:FBItechnique显示文摘Le H Leijssen P Duarte M 2011Eur Spine J2011,20,5:1
4Thoracolumbar imbalance analysis tbr osteoto- my planification using a new method:FBl technique显示文摘Le Huec JC Leijssen P Duarte M 2011Eur Spitle J2011,205,:1
5Incidence and clinical factors related with nosocomial infection in children with heart surgery 显示文摘Duarte Raya F Moreno-Ibarra LE de Anda-Gomez M 2010Rev Med Inst Mex Seguro Soc2010,48,6:1
6Thoracolumbar imbalance analysis for osteotomy planification using a new method:FBI technique显示文摘Le H Leijssen P Duarte M 2011Eur Spine J2011,20,5:1
7Thoracolumbar imbalance analysis for osteotomy planification using a new method:FBI technique显示文摘Le Huec JC Leijssen P Duarte M 2011Eur Spine J2011,20,:1
8Involvement of thromboxane A2 in the endothelium-dependent contractions induced by myricetin in rat isolated aorta显示文摘Jimenez R Andriambe LE Duarte J 1999Br J Pharmacol1999,127,7:1
9Thoracolum-bar imbalance analysis for osteotomy planification using anew method : FBI technique 显示文摘Le Huec J C Leijssen P Duarte M 2011Eur Spine J2011,20,5:1
10The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching 显示文摘Suchting S Freitas C Le Noble F Benedito R Breant C Duarte A 2007Proc Nail Acad Sci USA2007,104,9:1
11Thoracolumbar imbalanceanalysis for osteotomy planiiication using a new method:FBI tech-nique 显示文摘Le Huec JC Leijssen P Duarte M 2011Eur Spine J2011,205,:1
12Depth-sensing indentation modeling for determination of Elastic modulus of thin films显示文摘A. Tricoteaux G. Duarte D. Chicot E. Le Bourhis E. Bemporad J. Lesage 2009Mechanics of Materials2009,,:1
13Isolated symptomatic cervical spinous process fracture requiring surgery:Case report显示文摘Hirsh LF Duarte LE Wolfson EH 1991J Neurosurg1991,75,1:1
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