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| 1 | 相变储能大体积混凝土的控温性能显示文摘提出相变控温储能材料机敏控制混凝土结构温度裂缝技术途径.在混凝土浇注过程中将相变材料掺入使之与混凝土结构一体化,利用相变材料在特定温度范围的热效应控制混凝土内部温度场,从而机敏控制温度应力防止温度裂缝.通过自行设计的温度测试系统,对相变控温混凝土控温性能进行实测研究,结果表明:相变材料不但可以降低大体积混凝土的最高绝热温升值,而且可以降低大体积混凝土升温速度和降温速度,从根本上防止了大体积混凝土温度裂缝的出现. | 史巍 张雄 Juergen Dreyer | 2010 | 同济大学学报(自然科学版)2010，38，4： | 32 |
| 2 | Calcium-dependent modulation and plasma membrane targeting of the AKT2 potassium channel by the CBL4/ ClPK6 calcium sensor/protein kinase complex显示文摘 | Katrin Held Franqois Pascaud Christian Eckert Pawel Gajdanowicz Kenji Hashimoto Claire Corratge-Faillie Jan Niklas Offenborn Benoit Lacombe Ingo Dreyer Jean-Baptiste Thibaud Jorg Kudla | 2011 | Cell Research2011，21，7： | 23 |
| 3 | China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design显示文摘 | Rachel P Dreyer Xi Li Xue Du Nicholas S Downing Li Li Hai-Bo Zhang Fang Feng Wen-Chi Guan Xiao Xu Shu-Xia Li Zhen-Qiu Lin Frederick A Masoudi John A Spertus Harlan M Krumholz Li-Xin Jiang | 2016 | Chinese Medical Journal2016，，1： | 13 |
| 4 | 相变控温大体积混凝土抗裂性能研究显示文摘混凝土结构温度裂缝,尤其是大体积混凝土工程中的温度裂缝,缺乏有效控制措施。提出了相变控温储能材料机敏控制混凝土结构温度裂缝新的技术途径。通过自行设计的温度裂缝圆环试验测温系统,对普通砂浆和相变控温砂浆抗裂性进行评价,结果表明,相变材料在大体积混凝土中具有较好的控温效果,从而可以提高混凝土抵抗温度裂缝的能力,为解决大体积混凝土温度裂缝提出了新方法。 | 史巍 张雄 Juergen Dreyer | 2008 | 新型建筑材料2008，35，5： | 12 |
| 5 | Successful endovascular treatment in patients with acute thromboembolic ischemia of the lower limb including the crural arteries显示文摘AIM To examine the efficacy and safety of the 6 French(6F) Rotarex~S catheter system in patients with acute limb ischemia(ALI) involving thromboembolic occlusion of the proximal and mid-crural vessels.METHODS The files of patients in our department with ALI between 2015 and 2017 were examined. In seven patients, the Rotarex~S catheter was used in the proximal segment of the crural arteries. Data related to the clinical examination, Doppler sonography, angiography and followup from these patients were further used for analysis.RESULTS Two patients(29%) had thrombotic occlusion of the common femoral artery, and the remaining five exhibited thrombosis of the superficial femoral artery and popliteal artery. Mechanical thrombectomy was performed in all cases using a 6F Rotarex~S catheter. Additional Rotarex~S catheter thrombectomy due to remaining thrombus formation with no reflow was performed in the anterior tibial artery in two of seven cases(29%), in the tibiofibular tract and posterior tibial artery in two of seven cases(29%) and in the tibiofibular tract and fibular artery in the remaining three of seven cases(43%). Ischemic symptoms resolved promptly in all, and none of the patients experienced a procedural complication, such as crural vessel dissection, perforation or thrombus embolization.CONCLUSION Mechanical debulking using the 6F Rotarex~S catheter system may be a safe and effective treatment option in case of thrombotic or thromboembolic occlusion of the proximal and mid-portion of crural arteries. | Sorin Giusca Dorothea Raupp Dirk Dreyer Christoph Eisenbach Grigorios Korosoglou | 2018 | World Journal of Cardiology2018，10，10： | 7 |
| 6 | The fungal UmSrt1 and maize ZmSUT1 sucrose transporters battle for plant sugar resources显示文摘The biotrophic fungus Ustilago maydis causes corn smut disease, inducing tumor formation in its host Zea mays. Upon infection, the fungal hyphae invaginate the plasma membrane of infected maize cells, establishing an interface where pathogen and host are separated only by their plasma membranes. At this interface the fungal and maize sucrose transporters, UmSrt1 and ZmSUT1, compete for extracellular sucrose in the corn smut/maize pathosystem. Here we biophysically characterized ZmSUT1 and UmSrt1 in Xenopus oocytes with respect to their voltage-,pH-and substrate-dependence and determined affinities toward protons and sucrose. In contrast to ZmSUT1,UmSrt1 has a high affinity for sucrose and is relatively pH-and voltage-independent. Using these quantitative parameters, we developed a mathematical model to simulate the competition for extracellular sucrose at the contact zone between the fungus and the host plant. This approach revealed that UmSrt1 exploits the apoplastic sucrose resource, which forces the plant transporter into a sucrose export mode providing the fungus with sugar from the phloem. Importantly, the high sucrose concentration in the phloem appeared disadvantageous for the ZmSUT1, preventing sucrose recovery from the apoplastic space in the fungus/plant interface. | Anke Wittek Ingo Dreyer Khaled A.S. Al-Rasheid Norbert Sauer Rainer Hedrich Dietmar Geiger | 2017 | Journal of Integrative Plant Biology2017，59，6： | 6 |
| 7 | Immunosuppression for in vivo research: state-of-the-at protocols and experimental approaches显示文摘几乎,用非自体同源的房间,织物或机关移植的每试验性的治疗策略在临床的翻译前在小、大的动物模型被测试。因为这些策略在大多数情况中要求免疫力的抑制,抑制免疫力的协议是在移植实验的一个关键元素。然而,没有详细知识,标准抑制免疫力的协议经常在特别试验性的背景以内并且在选择模型种类关于他们的功效被使用。如此的协议的优化对到人的病人的试验性的结果的翻译恰当,因此,保证推进调查。这评论与种类特定的药 metabolization 和副作用的考虑关于抑制免疫力的药类以及他们的剂量和应用程序政体总结当前的知识。它也总结新奇 immunomodulatory 策略的当代的知识,例如间充质的干细胞或抗体的使用。因此,这评论被打算用作一个最先进的概要让研究人员精制应用试验性的免疫力的抑制和 immunomodulation 策略提高现出症状之前的潜的移植研究的预兆的价值。 | Rita Diehl Fabienne Ferrara Claudia Müller Antje Y Dreyer Damian D McLeod Stephan Fricke Johannes Boltze | 2017 | Cellular & Molecular Immunology2017，14，2： | 5 |
| 8 | Disease control with sunitinib in advanced intrahepatic cholangiocarcinoma resistant to gemcitabine-oxaliplatin chemotherapy显示文摘Advanced cholangiocarcinoma is associated with poor prognostic survival and has limited therapeutic options available at present. The importance of angiogenesis and expression of pro-angiogenic factors in intrahepatic forms of cholangiocarcinoma suggest that therapies targeting angiogenesis might be useful for the treatment of this disease. Here we report three cases of patients with advanced intrahepatic cholangiocarcinoma progressive after standard chemotherapy and treated with sunitinib 50 mg/d in 6-wk cycles of 4 wk on treatment followed by 2 wk off treatment(Schedule 4/2). In all three patients, sunitinib treatment was associated with a sustained disease control superior to 4 mo, patients achieving either a partial response or stable disease. A reduction in tumor size and density was observed in all cases, suggesting tumor necrosis as a result of sunitinib treatment in these patients. In addition, sunitinib was generally well tolerated and the occurrence of side effects was managed with standard medical interventions, as required. Our results suggest that sunitinib therapy maybe associated with favorable outcomes and tolerability in patients with advanced cholangiocarcinoma. Those observations contributed to launch a prospective phase Ⅱ multicenter trial investigating sunitinib in advanced intrahepatic cholangiocarcinoma(SUN-CK study; NCT01718327). | Chantal Dreyer Marie-Paule Sablin Mohamed Bouattour Cindy Neuzillet Maxime Ronot Safi Dokmak Jacques Belghiti Nathalie Guedj Valérie Paradis Eric Raymond Sandrine Faivre | 2015 | World Journal of Hepatology2015，7，6： | 4 |
| 9 | 德国柏林亚洲艺术博物馆藏克孜尔石窟壁画显示文摘20世纪初,德国考察队从克孜尔石窟揭取了大量壁画,其中的大部分现藏于德国柏林亚洲艺术博物馆。然而,考察队对这些壁画所出洞窟的记录存在一定错漏。近年,新疆龟兹研究院与德国柏林亚洲艺术博物馆合作,对该馆所藏克孜尔石窟壁画进行了深入调查,并通过实地考察与逐一核对,确认了大部分德藏克孜尔壁画所属的洞窟及原来所在的位置,为相关研究提供了便利。 | 赵莉 Lilla Russell-Smith Caren Dreyer Ines Buschmann 祁梅香 | 2015 | 文物2015，，6： | 4 |
| 10 | Distributed Differences Structures Underlie Gating between the Kin Channel KAT1 and the Kout Channel SKOR显示文摘 | Janin Riedelsberger Tripti Sharma Wendy Gonzalez Pawel Gajdanowicz Samuel Elias Morales-Navarro Carlos Garcia-Mata Bernd Mueller-Roeber Fernando Danilo Gonzalez-Nilo Michael R. Blatt Ingo Dreyer | 2010 | Molecular Plant2010，3，1： | 2 |
| 11 | 利用补充真实世界数据研究获得更深层次的认识显示文摘随着患者、医护人员、药品注册人员和政策决定者对现实世界中各种诊疗手段的安全性和有效性相关证据的迫切需求,我们需要新的研究设计来高效有效地对此类问题进行评估。与此同时,越来越多的二手数据可以用来提供此种相关证据,常用的二手数据包括电子医疗档案和医疗保险数据等。补充真实世界数据研究同时利用了现有二手数据和通过医生/患者收集的一手数据,并将两者进行结合。在现有数据的基础上,补充真实世界数据研究可以集中精力收集缺失的重要信息来满足研究目的。本文将对补充真实世界数据研究进行介绍,包括研究设计要素,研究的优点和局限性,实施要点以及应用实例等。 | CD Mack L Parmenter E Brinkley L Liu NA Dreyer | 2016 | 药物流行病学杂志2016，25，1： | 2 |
| 12 | Submicron and ultrafine grained hardmetals for microdrills and metal cutting inserts显示文摘 | G Gille B Szesny K Dreyer H van den Berg J Schmidt T Gestrich G Leitner | 2002 | International Journal of Refractory Metals and Hard Materials2002，，1： | 2 |
| 13 | Nonverbal communication accuracy in married couples: Relationship with marital complaints显示文摘 | Sabatelli R M Buck R Dreyer A | 1982 | Journal of Personality and Social Psychology1982，43，5： | 1 |
| 14 | Confidence Interval Estimaters for Parameters Associated with Quantitative Structure Activity Relationship显示文摘 | DIETRICH W S DREYER N D HANSCH C | 1980 | Med Chem1980，23，11： | 1 |
| 15 | Near-net-shaping in the hardmetal industry 显示文摘 | K R?diger H van den Berg K Dreyer | 2002 | Refractory Metals & Hard Materials2002，18，23： | 1 |
| 16 | An open, randomized, parallel-group study to compare the efficacy and safety profile of inhaled human insulin ( Exubera) with mefformin as adjuctive therapy in patients with type 2 diabetes poorly controlled on a sulfonylurea显示文摘 | Barnett AH Dreyer M Lange P | 2006 | Diabetes Care2006，29，6： | 1 |
| 17 | Microwave sintering of hardmetals显示文摘 | RODIGER K DREYER K GERDES T | 1998 | International Journal of Refractory Metals and Hard Materials1998，16，： | 1 |
| 18 | Clinical characterization of left ventricular noncompaction in children : a relatively common form of cardiomyopathy显示文摘 | PIGNATELLI R H MCMAHON C J DREYER W J | 2003 | Circulation2003，108，26： | 1 |
| 19 | Stomatal regulation of photosynthesis in apple leaves: evidence for different water-use strategies between two euhivars显示文摘 | Massonnet C Costes E Rambal S Dreyer E Regnard J L | 2007 | Annals of Botany2007，100，6： | 1 |
| 20 | Address on the Desirability of Publishing a New Edition of Isaac Newton's Collected Works 显示文摘 | Dreyer J | 1924 | Monthly Notices of the Royal Astronomical Society1924，，4： | 1 |
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