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| 1 | Effect of alcohol consumption on liver stiffness measured by transient elastography显示文摘AIM:To determine the evolution of transient elastography(TE) in patients with alcoholic liver disease according to alcohol cessation or continuation.METHODS:We retrospectively selected in our local database all patients who had two TE between June 2005 and November 2010 with chronic alcohol excessive consumption and excluded those with associated cause of liver disease.TE was performed at least one week apart by senior operator.TE examinations with less than ten successful measures or with an interquartile range above 30% were excluded.We retrospectively reviewed file of all patients to include only patient followed up by trained addictologist and for which definite information on alcohol consumption was available.Concomitant biological parameters [aspartate amino transferase(AST),alanine amino transferase and gamma-glutamyl transpeptidase(GGT)] within 4 wk of initial and final TE were recorded.Putative fibrosis score according to initial and final TE were determined with available cut-off for alcoholic liver disease and hepatitis C.Initial and final putative fibrosis score were compared according to alcohol consumption during follow-up.RESULTS:During the study period 572 patients had TE examination for alcoholic liver disease and 79 of them had at least two examinations.Thirty-seven patients met our criteria with a median follow-up of 32.5 wk.At the end of the study,13(35%) were abstinent,and 24(65%) relapsers.Eight patients had liver biopsy during follow-up.TE decreased significantly during follow-up in 85% of abstinent patients [median(range):-4.9(-6.1,-1.9)],leading to a modification of the putative fibrosis stage in 28%-71% of patient according to different cut-off value.In relapsers TE increased in 45% and decreased in 54% of patient.There was no statistical difference between initial and final TE in relapsers.In the overall population,using 22.6 kPa as cut-off for cirrhosis,4 patients had cirrhosis at initial TE and 3 patients had cirrhosis at final TE.Using 19.5 kPa as cut-off for cirrhosis,7 patients had cirrhosis at initial TE and 5 patients had cirrhosis at final TE.Using 12.5 kPa as cut-off for cirrhosis,16 patients had cirrhosis at initial TE and 15 patients had cirrhosis at final TE.Evolution of biological data was in accordance with the relapse or abstinent status:abstinence ratio(duration of abstinence/duration follow-up) was correlated with AST ratio(r =-0.465,P = 0.007) and GGT ratio(r =-0.662,P<0.0001).GGT was correlated with initial(r = 0.488,P = 0.002) and final TE(r = 0.49,P<0.005).Final TE was correlated with AST(r = 0.362,P<0.05).Correlation between TE ratio and AST ratio(r = 0.44,P = 0.01) revealed that TE varied proportionally to AST for all patients irrespective of their alcohol status.The same relationship was observed between TE ratio and GGT ratio(r = 0.65,P<0.0001).Evolution of TE was significantly correlated with the ratio of time of abstinence to observation time(r =-0.387,P = 0.016) and the evolution of liver enzymes.CONCLUSION:TE significantly decreased with abstinence.Results of TE in alcoholic liver disease cannot be interpreted without taking into account alcohol consumption and liver enzymes. | Edouard Bardou-Jacquet Ludivine Legros Draman Soro Marianne Latournerie Anne Guillygomarc'h Caroline Le Lan Pierre Brissot Dominique Guyader Romain Moirand | 2013 | World Journal of Gastroenterology2013，19，4： | 20 |
| 2 | A retrospec- tive review of diabetic nephropathy patients during refer- ral to the suburban nephrology clinic显示文摘 | Menon R Mohd Noor FS Draman CR | 2012 | Sandi J Kidney Dis Transpl2012，23，5： | 1 |
| 3 | Impact of tailing dams on land and water environments Makeng underground iron mine 显示文摘 | Dramane Traore Chen Zhihua Julia Ellis Burnet | 2008 | Environmental Research Journal2008，2，5： | 1 |
| 4 | Cell signaling mechanisms of gustatory perception of lipids:can the taste cells be the target of anti-obesity agents显示文摘 | Dramane G Akpona S Simonin A M Besnard P Khan N A | | 0，，22： | 1 |
| 5 | A retrospective v:view of diabetic nephropathy patients during referral to the sub - urba: neph- relogy clinlc显示文摘 | Menon R Mohdnoor FS Draman CR | 2012 | Saudi J Kidney Dis Transpl2012，23，5： | 1 |
| 6 | Selective intra-arterial calcium stimulation with hepatic venous sampling in investigation of hyperinsulinemic hypoglycemia显示文摘 | Draman MS Ahern T Smith T | | 0，，2： | 1 |
| 7 | Associa-tion between Sleep Disruption and Levels of Lipids in Caucasians withType 2 Diabetes显示文摘 | Wan Mahmood WA Draman Yusoff MS Behan LA | 2013 | Int J Endocrinol2013，2013，34： | 1 |
| 8 | A retrospective review of diabetic nephropathy patients during referral to the suburban nephrology clinic显示文摘 | Menon R Mohd Noor FS Draman CR | 2012 | Saudi J Kidney Dis Transpl2012，23，5： | 1 |
| 9 | A retrospective review of diabetic nephropathy patients during referral to the suburban nephrology clinic 显示文摘 | Menon R Mohd Noor FS Draman CR | 2012 | Saudi J Kidney Dis Transpl2012，23，5： | 1 |
| 10 | EHD flow and collection efficiency of a DBD ESP in wire-to-plane and plane-to-plane configurations显示文摘 | ZOUZOU N DRAMANE B MOREAU E | 2011 | IEEE Transactions on Industry Application2011，47，1： | 1 |
| 11 | A clone-based graphical modeler and mathematical model generator for optimal production planning in process industries显示文摘 | Draman M Altinel I K Bajgoric N | 2002 | Euro J Operational Research2002，137，3： | 1 |
| 12 | EHD flow and collection efficiency of a DBD ESP in wire-to-plane and plane-to-plane configurations显示文摘 | Noureddine Z Dramane B Moreau E | 2011 | IEEE Transactions on Industry Application2011，47，1： | 1 |
| 13 | Clinical out- comes of acute kidney injury patients treated in a single-cen- ter, sub-urban satellite hospital 显示文摘 | Mohd Nor FS Draman CR Seman MR | 2015 | Saudi J Kidney Dis Transpl2015，26，4： | 1 |
| 14 | Immigration, Growth, and Unemployment: Panel VAR Evidence from OECD Countries显示文摘 | Ekrame Boubtane Dramane Coulibaly Christophe Rault | 2013 | Labour2013，，4： | 1 |
| 15 | EHD flow and collection efficiency of a DBD ESP in wire-to-plane and plane-to-plane configurations显示文摘 | Zouzou N Dramane B Moreau E | 2011 | IEEE Transaction on Industry Applications2011，47，1： | 1 |
| 16 | EHD flow and collection efficiency of a DBD ESP in wire-to-plane and plane-to-plane configurations显示文摘 | Zouzou N Dramane B Moreau E | 2011 | IEEE Transaction on Industry Applications2011，47，1： | 1 |
| 17 | Impact of tailing dams on land and water environments Makeng underground iron mine显示文摘 | Dramane Traore Chen Zhihua Julia Ellis Burnet | 2008 | EnvironmentalResearch Journa2008，2，5： | 1 |
| 18 | A retrospective review of diabetic nephropathy patients during referral to the suburban neph- rology clinic 显示文摘 | Menon R Mohd Noor FS Draman CR | 2012 | Saudi J Kidney Dis Transpl2012，23，5： | 1 |
| 19 | Secondary resistance to cabergoline therapy in a macroprolactinoma: a case report and literature review 显示文摘 | Behan LA Draman MS Moran C | 2011 | Pituitary2011，14，4： | 1 |
| 20 | The maximum likelihood identification method applied to insect morphometric data显示文摘To distinguish species or populations using morphometric data is generally processed through multivariate analyses,in particular the discriminant analysis.We explored another approach based on the maximum likelihood method.Simple statistics based on the assumption of normal distribution at a single variable allows to compute the chance of observing a particular data(or sample) in a given reference group.When data are described by more than one variable,the maximum likelihood(MLi) approach allows to combine these chances to find the best fit for the data.Such approach assumes independence between variables.The assumptions of normal distribution of variables and independence between them are frequently not met in morphometrics,but improvements may be obtained after some mathematical transformations.Provided there is strict anatomical correspondence of variables between unknown and reference data,the MLi classification produces consistent classification.We explored this approach using various input data,and compared validated classification scores with the ones obtained after the Mahalanobis distance-based classification.The simplicity of the method,its fast computation,performance and versatility,make it an interesting complement to other classification techniques. | Jean-Pierre Dujardin Sebastien Dujardin Dramane Kaba Soledad Santillan-Guayasamin Anita G.Villacis Sitha Piyaselakul Suchacla Sumruayphol Yudthana Samung Ronald Morales Vargas | 2017 | Zoological Systematics2017，42，1： | 1 |
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