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| 1 | Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models显示文摘表示为基于 radiopharmaceutical 的成像为生物体之发光成像或 HSV1 thymidine kinase (HSV1-TK ) 编码任何一个萤火虫酶(fLuc ) 的记者 transgene 的 lentiviral 向量的二种新类型被构造监视人的胚胎的干细胞(hESC ) 在在移植以后的活老鼠的嫁接和增长。任何一个 transgene 的组成的表示没在文化改变 hESCs 的性质。我们下次在 SCID 鼠标监视了 teratomas 的形成到测试(1 ) 是否修改基因的 hESCs 维持他们的发展 pluripotency,并且(2 ) 是否支撑了记者基因表示,允许 noninvasive,在一个活鼠标模型的 hESC 衍生物的整个身体的成像。我们在接种以后从修改基因的房间以及野类型的 hESCs 2-4 月的两种类型观察了 teratoma 形成。用一个光成像系统,从 fLuc-transduced hESCs 的生物体之发光容易在在摸得出的肿瘤能被检测以前,长忍受 teratomas 的老鼠被检测。开发一个 noninvasive 成像方法对诊所更容易地可译,我们也利用了 HSV1-TK 和它的特定的底层, 1-(2 鈥 ? deoxy-2 鈥 ?fluoro- 尾 - D-arabinofuranosyl )-5-[125I]iodouracil ([125I ] FIAU ) ,记者 / 探查对。在全身的管理以后,[125I ] FIAU 是仅仅由编码 transgene 的 HSV1-TK 酶的 phosphorylated 并且在 transduced 以内保留(并且移植) 房间,由单个光子的排放允许敏感、量的成像计算了断层摄影术。象这些那样的 Noninvasive 成像方法可以使我们能在实时接受者以内重复地监视移植人的干细胞的存在和分发在上一通过记者基因的表达式长期。 | Martin G Pomper Holly Hammond Xiaobing Yu Zhaohui Ye Catherine A Foss Doris D Lin James J Fox Linzhao Cheng | 2009 | Cell Research2009,19,3: | 9 |
| 2 | Aphis (Hemiptera: Aphididae) species groups found in the Midwestern United States and their contribution to the phylogenetic knowledge of the genus显示文摘类蚜虫属 Linnaeus 的发展史, 1 758 首先从在美国的中西部收集的标本被造。一个数据矩阵与有翼、无翅的胎生的女性的各自的字符国家与 68 种类和 41 个词法字符被构造。用 UPGMA (有算术平均数的未加权的对组方法) 执行的分析的 Dendrogram 拓扑学,最大的吝啬和细胞色素 Oxidase 的贝叶斯的分析我,延伸因素 1-α
并且主要 endosymbiont Buchnera aphidicola 16S 序列不适合。贝叶斯的分析强烈支持了种系发生的树的大多数终端节点。发展史被 COI 的 EF1-α 和 EF1-α 强烈支持分子的数据与词法人物结合了。它没被 COI 或 Buchnera aphidicola 16S 的单个分析支持。从贝叶斯的发展史的结果给 4 个主要种类组看:asclepiadis, fabae, gossypii,和 middletonii。结果地方蚜虫属和类 Protaphis Börner 的种类, 1952, Toxoptera Koch, 1856 并且 Xerobion Nevsky, 1928 在 monophyletic clade。词法人物也 monophyly 支持这。发展史证明北美的 middletonii 种类组的 monophyletic clade 属于类 Protaphis:P。debilicornis (吉勒特与帕尔默, 1929 ) ,梳子。nov, P。echinaceae (拉各斯和 Voegtlin, 2009 ) ,梳子。nov,和 P。middletonii (托马斯, 1879 ) 。类 Toxoptera 应该被认为蚜虫属的亚属(stat。nov ) 。分析也显示当前的类 Iowana Frison, 1954 应该被认为蚜虫属的亚属(stat。nov ) 。 | Doris M. Lagos David J. Voegtlin Armelle Coeur d'aciert Rosanna Giordano | 2014 | Insect Science2014,21,3: | 2 |
| 3 | Tucker,performance of wdm ring and bus networks in the present of homodyne crosstalk显示文摘 | Jonathan P R Lacey Rodney S | 1999 | Journal of Lightwave Technology1999,17,3: | 1 |
| 4 | Reusing semi-specified behavior models in systems analysis and design显示文摘 | Iris R B Dori D Shmuel K | 2009 | Software and Systems Modeling2009,8,2: | 1 |
| 5 | Effect of platelet-rich plasma on the healing of intra-bony defects treated with a natural bone mineral and a col agen membrane显示文摘 | Dori F Huszar T Nikolidakis D | | 0,,: | 1 |
| 6 | Object-Process Based Graphics Recogni- tion Class Library:Principles and Applications Software 显示文摘 | LIU Wen-yin D Dori | 1999 | Practice and Experience1999,29,15: | 1 |
| 7 | Modeling design patterns for semi-automatic reuse in system design显示文摘 | Galia S Iris R B Dori D | 2010 | J of Database Management2010,21,1: | 1 |
| 8 | Conceptual modeling in systems biology fosters empirical findings: The mRNA lifecycle显示文摘 | Dori D Choder M | 2007 | PLoS ONE2007,2,9: | 1 |
| 9 | Effect of platelet-rich plasma on the healing of intrabony defects treated with Beta tricalcium phosphate and expanded polytetrafluoroethylene membranes 显示文摘 | Dori F Huszar T Nikolidakis D | 2008 | J Periodontol2008,79,4: | 1 |
| 10 | Purification of a 41kDa cod-allergenic protein显示文摘 | Galland A V Dory D Pons L | | 0,,: | 1 |
| 11 | From raster to vectors: extracting visual information from line drawings显示文摘 | WENYIN L DORI D | 1999 | Pattern Analysis & Applications1999,2,1: | 1 |
| 12 | Myeloma renal disease: presentation and outcome 显示文摘 | Doris T Kathrine G Kieron D | 2006 | Nephron C|in Pract2006,10,1: | 1 |
| 13 | From Raster to Vectors: Extracting Visual Information from Line Drawings显示文摘 | W Y Liu D Dori | 1999 | Pattern Analysis and Application1999,2,1: | 1 |
| 14 | Full-spectrum cardiac surgery through a minimal incision:mini-sternotomy (lower half) technique显示文摘 | Doty D B Di Russo G B Dory J R | 1998 | Ann Thorac Surg1998,65,2: | 1 |
| 15 | Development of a quantitative Real -Time TaqMan PCR assay for determination of the minimal dose of Mycoplasma hyopneumoniae strain 116 required to induce pneumonia in SPF pigs 显示文摘 | Marois C Dory D Fablet C | 2010 | J Appl Microbiol2010,108,5: | 1 |
| 16 | Reproductive factorsand serum uric acid levels in females from the generalpopulation: the KORA F4 study 显示文摘 | Doris S Angela D Barbara T | 2012 | Plos One2012,7,3: | 1 |
| 17 | The TIR domain of TIR-NB-LRR resistance proteins is a signaling domain involved in cell death in-duction显示文摘 | Michal R Doris B Jonathan D | 2009 | Mol Plant-Microbe Interact2009,22,2: | 1 |
| 18 | Modes of Theorizing in Strategic Human Resource Management:Tests of Universalistic,Contingency,and Configurational Performance Predic-tions 显示文摘 | Delery J E Dory D H | 1996 | Academy of Management Journal1996,39,4: | 1 |
| 19 | Sparse pixel vectorization:an algorithm and its performance evaluation显示文摘 | Dori D Liu W | 1999 | IEEE Transaction on Pattern Analysis and Machine Intelligence1999,21,3: | 1 |
| 20 | Modes of theorizing in strategic human resource management : tests of universalistic, contingency, and configurational performance predictons显示文摘 | Delery J E Dory D H | 1996 | Academy of Management Journal1996,39,4: | 1 |