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| 1 | Inhibitory effect of Jeju endemic seaweeds on the production of pro-inflammatory mediators in mouse macrophage cell line RAW 264.7显示文摘Seaweed has been used in traditional cosmetics and as a herbal medicine in treatments for cough,boils,goiters,stomach ailments,and urinary diseases,and for reducing the incidence of tumors,ulcers,and headaches.Despite the fact that seaweeds are frequently used in the practice of human health,little is known about the role of seaweed in the context of inflammation.This study aimed to investigate the influence of Jeju endemic seaweed on a mouse macrophage cell line(RAW 264.7) under the stimulation of lipopolysaccharide(LPS).Ethyl acetate extracts obtained from 14 different kinds of Jeju seaweeds were screened for inhibitory effects on pro-inflammatory mediators.Our results revealed that extracts from five seaweeds,Laurencia okamurae,Grateloupia elliptica,Sargassum thun-bergii,Gloiopeltis furcata,and Hizikia fusiformis,were potent inhibitors of the production of pro-inflammatory mediators such as nitric oxide(NO),prostaglandin E2(PGE2),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α).Based on these results,the anti-inflammatory effects and low cell toxicity of these seaweed extracts suggest potential thera-peutic applications in the regulation of the inflammatory response. | Eun-Jin YANG Ji-Young MOON Min-Jin KIM Dong Sam KIM Chan-Shick KIM Wook Jae LEE Nam Ho LEE Chang-Gu HYUN | 2010 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2010，11，5： | 5 |
| 2 | Significant risk and associated factors of active tuberculosis infection in Korean patients with inflammatory bowel disease using anti-TNF agents显示文摘AIM:To evaluate the incidence and risk factors of Korean tuberculosis(TB) infection in patients with inflammatory bowel disease(IBD) undergoing anti-TNF treatment.METHODS:The data of IBD patients treated with anti-TNFs in 13 tertiary referral hospitals located in the southeastern region of Korea were collected retrospectively.They failed to show response or were intolerant to conventional treatments,including steroids or immunomodulators.Screening measures for latent TB infection(LTBI)and the incidence and risk factors ofactive TB infection after treatment with anti-TNFs were identified.RESULTS:Overall,376 IBD patients treated with antiTNF agents were recruited(male 255,mean age of anti-TNF therapy 32.5±13.0 years);277 had Crohn’s disease,99 had ulcerative colitis,294 used infliximab,and 82 used adalimumab.Before anti-TNF treatment,screening tests for LTBI including an interferon gamma release assay or a tuberculin skin test were performed in 82.2%of patients.Thirty patients(8%)had LTBI.Sixteen cases of active TB infection including one TB-related mortality occurred during 801 personyears(PY)follow-up(1997.4 cases per 100000 PY)after anti-TNF treatment.LTBI(OR=5.76,95%CI:1.57-21.20,P=0.008)and WBC count<5000 mm3(OR=4.5,95%CI:1.51-13.44,P=0.007)during follow-up were identified as independently associated risk factors.CONCLUSION:Anti-TNFs significantly increase the risk of TB infection in Korean patients with IBD.The considerable burden of TB and marked immunosuppression might be attributed to this risk. | Eun Soo Kim Geun Am Song Kwang Bum Cho Kyung Sik Park Kyeong Ok Kim Byung Ik Jang Eun Young Kim Seong Woo Jeon Hyun Seok Lee Chang Heon Yang Yong Kook Lee Dong Wook Lee Sung Kook Kim Tae Oh Kim Jonghun Lee Hyung Wook Kim Sam Ryong Jee Seun Ja Park Hyun Jin Kim | 2015 | World Journal of Gastroenterology2015，21，11： | 5 |
| 3 | Effect of alloying elements and austenite destabilization heat treatment on graphitization of high chromiumcast iron 显示文摘 | Chang Sam Kyu Kim Dong Gyu and Choi | 1992 | International1992，32，11： | 1 |
| 4 | Long‐term incidence, risk factors, and management of biliary complications after adult living donor liver transplantation显示文摘 | Shin Hwang Sung‐Gyu Lee Kyu‐Bo Sung Kwang‐Min Park Ki‐Hun Kim Chul‐Soo Ahn Young‐Joo Lee Sung‐Koo Lee Gyu‐Sam Hwang Deok‐Bog Moon Tae‐Yong Ha Dong‐Sik Kim Jae‐Pil Jung Gi‐Won Song | 2006 | Liver Transpl2006，，5： | 1 |
| 5 | CO2 sequestration in depleted oil and gas reservoirs-caprock characterization and storage capacity显示文摘 | Zhaowen Li Mingzhe Dong Shuliang Li Sam Huang | 2006 | Energy Conversion and Management2006，47，： | 1 |
| 6 | Self-healing polymeric materials: A review of recent developments显示文摘 | Dong Yang Wu Sam Meure David Solomon | 2008 | Prog Polym Sci2008，33，： | 1 |
| 7 | Non-lipid effects of rosuvastatin–fenofibrate combination therapy in high-risk Asian patients with mixed hyperlipidemia显示文摘 | Sang-Hak Lee Kyoung-Im Cho Jang-Young Kim Young Keun Ahn Seung-Woon Rha Yong-Jin Kim Yun-Seok Choi Si Wan Choi Dong Woon Jeon Pil-Ki Min Dong-Ju Choi Sang Hong Baek Kwon Sam Kim Young Sup Byun Yangsoo Jang | 2012 | Atherosclerosis2012，，： | 1 |
| 8 | Functionality of milk protein concentrate: Effect of spray drying temperature显示文摘 | Yuan Fang Sam Rogers Cordelia Selomulya Xiao Dong Chen | 2011 | Biochemical Engineering Journal2011，，： | 1 |
| 9 | Low power design of DCT and IDCT for Iow bit rate video codecs显示文摘 | August Nathaniel J Ha Dong Sam | 2004 | IEEE Transactions on Multimedia2004，6，3： | 1 |
| 10 | Lentivirus-mediated gene transfer induces long-term transgen ic expression of BMP-2 in vitro and new bone formation in vivo显示文摘 | OSAMU SUGIYAMA DONG SUNG AN SAM P K | 2005 | Molecular Therapy2005，11，3： | 1 |
| 11 | Lentivirus - mediated gene transfer induces long - term transgene expression of BMP - 2 in vitro and new bone formation in vivo 显示文摘 | Osamu S Dong SA Sam PKK | 2005 | Mol Ther2005，3，： | 1 |
| 12 | Reconstruction of inferior right hepatic veins in living donor liver transplantation using right liver grafts显示文摘 | Shin Hwang Tae‐Yong Ha Chul‐Soo Ahn Deok‐Bog Moon Ki‐Hun Kim Gi‐Won Song Dong‐Hwan Jung Gil‐Chun Park Jung‐Man Namgoong Sung‐Won Jung Sam‐Youl Yoon Kyu‐Bo Sung Gi‐Young Ko Byungchul Cho Kyoung Won Kim Sung‐Gyu Lee | 2012 | Liver Transpl2012，，2： | 1 |
| 13 | Low power design of DCT and IDCT for low bit rate video eodees显示文摘 | August N J Dong Sam Ha | 2004 | IEEE Transactions on Multimedia2004，6，3： | 1 |
| 14 | Hemodynamics‐compliant reconstruction of the right hepatic vein for adult living donor liver transplantation with a right liver graft显示文摘 | Shin Hwang Tae‐Yong Ha Chul‐Soo Ahn Deok‐Bog Moon Gi‐Won Song Ki‐Hun Kim Dong‐Hwan Jung Gil‐Chun Park Kyu‐Bo Sung Gi‐Young Ko Kyoung Won Kim Byungchul Cho Jung‐Man Namgoong Sung‐Won Jung Sam‐Youl Yoon Chun‐Soo Park Yo‐Han Park Hyeong‐Woo Park Hyo‐Jun Lee | 2012 | Liver Transpl2012，，7： | 1 |
| 15 | Effects of the impact angle variations on the erosion rate of glass in powder blasting process显示文摘 | Dong Sam Park Myeong-Woo Cho Honghee Lee | 2004 | Int J Adv Manuf Technol2004，23，： | 1 |
| 16 | The Child Play Behavior and Activity Questionnaire: A Parent-Report Measure of Childhood Gender-Related Behavior in China显示文摘 | Lu Yu Sam Winter Dong Xie | 2010 | Arch Sex Behav2010，39，3： | 1 |
| 17 | 显示文摘 | Won Ho Park Lim Jeong Dong Il Yoo Sam Hudson | 2004 | Polymer2004，45，： | 1 |
| 18 | Endoscopic histologic diagnosis of gastric GI submucosal tumors via the endoscopic submucosal dissection technique显示文摘 | Hang Lak Lee Oh Wan Kwon Kang Nyeong Lee Dae Won Jun Chang Soo Eun Oh Young Lee Yong Chul Jeon Dong Soo Han Byung Chul Yoon Ho Soon Choi Joon Soo Hahm Seung Sam Paik | 2011 | Gastrointestinal Endoscopy2011，，3： | 1 |
| 19 | Non-invasive electrical stimulation as a potential treatment for retinal degenerative diseases显示文摘More than 38.5 million people are estimated to be affected by blindness worldwide in 2020(Flaxman et al., 2017). Among the diseases that cause visual impairment, refractive errors are typically corrected with glasses and cataract with surgery. The leading causes of irreversible blindness nowadays are usually degenerative diseases related to the retina and its extending optic nerves. | Karen Chang Sam Enayati Kin-Sang Cho Tor P.Utheim Dong Feng Chen | 2021 | Neural Regeneration Research2021，16，8： | 1 |
| 20 | Assessment of Ground Subsidence Hazard Near an Abandoned Underground Coal Mine Using GIS显示文摘 | Ki - Dong Kim Sam LeeHyun - Joo Oh Jong - Kuk Choi | 2006 | Environ Geo12006，，50： | 1 |
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