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| 1 | PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix显示文摘Biofilms 是在细胞外的矩阵嵌入的微生物的联系表面的社区。Exopolysaccharide 是在维持 biofilm 建筑学并且保护居民 biofilm 细菌免受抗菌剂和主人免疫者攻击的伤害的细胞外的矩阵的一个批评部件。然而,指向矩阵 exopolysaccharides 的自我生产的因素,仍然糟糕被理解。这里,我们显示出那 PslG,在 Pseudomonas aeruginosa 涉及关键 biofilm 矩阵 exopolysaccharide Psl 的合成的蛋白质,阻止 biofilm 形成并且拆卸存在在外长地供应的在 nanomolar 集中的分钟以内的 biofilms。PslG 的水晶结构显示 endoglycosidase 的典型特征。PslG 主要破坏 Psl 矩阵从 biofilms 驱散细菌。PslG 处理显著地提高 biofilm 敏感到抗菌素和巨噬细胞房间,导致在一只老鼠的改进 biofilm 清理植入感染模型。而且, PslG 对大量 Pseudomonas 种类显示出 biofilm 抑制和拆卸活动,显示它在与 biofilm 相关的复杂并发症作斗争的大潜力。 | Shan Yu Tiantian Su Huijun Wu Shiheng Liu Di Wang Tianhu Zhao Zengjun Jin Wenbin Du Mei-Jun Zhu Song Lin Chua Liang Yang Deyu Zhu Lichuan Gu Luyan Z Ma | 2015 | Cell Research2015，25，12： | 13 |
| 2 | Plasminogen kringle 5-engineered glioma cells block migration of tumor- associated macrophages and suppress tumor vascularization and progres- sion.显示文摘 | Perri SR Nalbantoglu J Annabi B Koty Z Lejeune L Francois M Di Falco MR Beliveau R Galipeau J | 2005 | 中国神经肿瘤杂志2005，3，3： | 8 |
| 3 | Coronary physiology assessment in the catheterization laboratory显示文摘Physicians cannot rely solely on the angiographic appearance of epicardial coronary artery stenosis when evaluating patients with myocardial ischemia. Instead, sound knowledge of coronary vascular physiology and of the methods currently available for its characterization can improve the diagnostic and prognostic accuracy of invasive assessment of the coronary circulation, and help improve clinical decision-making. In this article we summarize the current methods available for a thorough assessment of coronary physiology. | Felipe Díez-delhoyo Enrique Gutiérrez-Ibanes Gerard Loughlin Ricardo Sanz-Ruiz María Eugenia Vázquez-álvarez Fernando Sarnago-Cebada Rocío Angulo-Llanos Ana Casado-Plasencia Jaime Elízaga Francisco Fernández Avilés Diáz | 2015 | World Journal of Cardiology2015，7，9： | 2 |
| 4 | Third genome size category of avian paramyxovirus serotype 1 (Newcastle disease virus) and evolutionary implications显示文摘 | Alíz Czeglédi Dorina Ujvári Eszter Somogyi Enik? Wehmann Ortrud Werner Béla Lomniczi | 2006 | Virus Research2006，，1： | 2 |
| 5 | Chromium adsorption by aligned carbon nanotubes supported ceria nanoparticles 显示文摘 | Di Z C Ding J Peng X J | 2006 | Chemosphere2006，62，5： | 1 |
| 6 | Phase 11显示文摘 | di LEO A GOMEZ HL AZIZ Z | 2008 | J Clin Oncol2008，26，34： | 1 |
| 7 | Fu- sarium oxysporum: exploring the molecular arsenal of a vascular wilt fungus 显示文摘 | DI PIETRO A MADRID M P CARACUEL Z | 2003 | Mol plant pathol2003，4，5： | 1 |
| 8 | Reassessing the joint roughness coefficient (JRC) estimation using Z2显示文摘 | YANG Z Y LO S C DI C C | 2011 | Rock Mechanics and Rock Engineering2011，34，3： | 1 |
| 9 | Pediatric RI- FLE for acute kidney injury diagnosis and prognosis for chil- dren undergoing cardiac surgery: a single-center prospective observational study显示文摘 | RICCI Z Di NARDO M IACOELLA C | 2013 | Pediatr Cardiol2013，34，6： | 1 |
| 10 | Quasi-monoenergetic electron beams generated from 7 TW laser pulses in N2 and He gas targets显示文摘 | CHEN Z L UNICK C VAFAEI-NAJAFABA- DI N | 2008 | Laser and Particle Beams2008，26，： | 1 |
| 11 | Impact of severe sepsis on serum and urinary biomarkers of acute kidney injury in critically ill children:an observational study显示文摘 | Di Nardo M Ficarella A Ricci Z | 2013 | Blood Purif2013，35，13： | 1 |
| 12 | Wood flour filled PP eomposites: eompatibilization and adhesion显示文摘 | Da'nya'di L Janecska T Szabo Z | 2007 | Composites Science and Technology2007，67，： | 1 |
| 13 | Calorimetric study on two biphenyl liquid crystals显示文摘 | Zou G L Tan Z C Di Y Y | | 0，，1： | 1 |
| 14 | Expression of delta-catenin isassociated with progression of human astrocytoma 显示文摘 | Minghao W Qianze D Di Z | 2011 | BMC Cancer2011，11，： | 1 |
| 15 | The effect of asperity order on the roughness of rock joints显示文摘 | YANG Z Y DI C C YEN K C | 2001 | International Journal of Rock Mechanics and Mining Sciences2001，38，5： | 1 |
| 16 | Recurrence of the world' s largest green-tide in 2009 in Yellow Sea, China: porphyra yezoensis aquaculture rafts confirmed as nusery for macoralgal blooms 显示文摘 | Liu D Y Keesign J K Dong Z J Zhen Y Di B P Shi Y J Fearns P Shi P | 2011 | Marine Pollution Bulletin2011，60，9： | 1 |
| 17 | Celastrol, a triterpene extracted from the chinese thunder of god vine is a potent proteasome inhibitor and suppres- ses human prostate cancer growth in nude mice显示文摘 | YANG Huan-jie CHEN Di CUI Q Z C | 2006 | Cancer Res2006，66，9： | 1 |
| 18 | Trichilin B, a novel limonoid with highly rearranged ring system from Trichilia connaroides显示文摘 | Geng Z L Fang X Di Y T et O1 | 2009 | Tetrahedron Letters2009，50，18： | 1 |
| 19 | Patent foramen ovale, sub- clinical cerebrovascular disease, and ischemic stroke in a population- based cohort显示文摘 | Di Tullio MR Jin Z Russo C | 2013 | J Am Coll Cardiol2013，62，1： | 1 |
| 20 | Preliminary Results of the Effect of Treatment of Hyperhomocysteinemia and Its Relationship With Inflammation, Coagulation Status, and Endothelial Function After Renal Transplantation显示文摘 | J. Manrique A. Diáz J.J. Gavira A. Hernández D. Pujante P. Errasti | 2005 | Transplantation Proceedings2005，，9： | 1 |
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