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| 1 | Non-quadratic Kelvin modes based plasticity criteria for anisotropic materials显示文摘 | Rodrigue Desmorat Roxane Marull | 2010 | International Journal of Plasticity2010，，3： | 1 |
| 2 | Nonlocal anisotropic damage model and related computational aspects for quasi-brittle materials显示文摘 | DESMORAT R GATUINGT F RAGUENEAU F | 2007 | Engineering Fracture Mechanics2007，74，10： | 1 |
| 3 | Incidence of large oe-sophageal varices in patients with cirrhosis: Application to prophyhaxis of first bleeding显示文摘 | Cales P Desmorat H Vinel JP | 1999 | Gut1999，31，： | 1 |
| 4 | Anisotropic damage law of evolution显示文摘 | Jean Lemaitre Rodrigue Desmorat Maxime Sauzay | 2000 | European Journal of Mechanics / A Solids2000，，2： | 1 |
| 5 | A two scale damage concept applied to fatigue 显示文摘 | LEMAITRE J SERMAGE J P Desmorat R | 1999 | Int J Fract1999，97，： | 1 |
| 6 | A two scale damage concept applied to fatigue显示文摘 | Sermage J P Desmorat R | 1999 | Int J Fract1999，97，： | 1 |
| 7 | Nonlocal Anisotropic Damage Model and Related Computatio-nal Aspects for Quasi-brittle Materials显示文摘 | Desmorat R Gatuingt F Ragueneau F | 2007 | Engineering Fracture Mechanics2007，74，： | 1 |
| 8 | Anisotropic damage law of evolution显示文摘 | Desmorat R Sauzay M | 2000 | Eur J Mech A/Solids2000，19，： | 1 |
| 9 | A two scale damage concept applied to fatigue 显示文摘 | Lemaitre J Sermage J P Desmorat R | 1999 | International Journal of Fracture1999，97，： | 1 |
| 10 | Nonlocal anisotropie damage model and related computational aspects for quasi-brittle materials 显示文摘 | Desmorat R Catuingt F Ragueneau F | 2007 | Engineering Fracture Mechanics2007，74，10： | 1 |
| 11 | Telaprevir- and boceprevir-based tritherapies in real practice for F3-F4 pretreated hepatitis C virus patients显示文摘AIM:To assess,in a routine practice setting,the sus-tained virologic response(SVR) to telaprevir(TPV) or boceprevir(BOC) in hepatitis C virus(HCV) nullresponders or relapsers with severe liver fibrosis.METHODS:One hundred twenty-five patients were treated prospectively for 48 wk with TPV or BOC + pegylated-interferon(peg-INF) α2a + ribavirin(PR) according to standard treatment schedules without randomization.These patients were treated in routine practice settings in 10 public or private health care centers,and the data were prospectively collected.Only patients with severe liver fibrosis(Metavir scores of F3 or F4 upon liver biopsy or liver stiffness assessed by elastography),genotype 1 HCV and who were null-responders or relapsers to prior PR combination therapy were included in this study.RESULTS:The Metavir fibrosis scores were F3 in 35(28%) and F4 in 90(72%) of the patients.In total,62.9% of the patients were null-responders and 37.1% relapsers to the previous PR therapy.The overall SVR rate at 24 wk post-treatment withdrawal was 59.8%.The SVR was 65.9% in the TPV group and 44.1% in the BOC group.Independent predictive factors of an SVR included a response to previous treatment,relapsers vs null-responders [OR = 3.9;(1.4,10.6),P = 0.0084],a rapid virological response(RVR) [OR 6.9(2.6,18.2),P = 0.001] and liver stiffness lower than 21.3 kPa [OR = 8.2(2.3,29.5),P = 0.001].During treatment,63 patients(50.8%) had at least one severe adverse event(SAE) of grade 3 or 4.A multivariate analysis identified two factors associated with SAEs:female gender [OR = 2.4(1.1,5.6),P = 0.037] and a platelet count below 150 × 103/ mm3 [OR = 5.3(2.3,12.4),P ≤ 0.001].CONCLUSION:More than half of these difficult-to-treat patients achieved an SVR and had SAEs in an actual practice setting.The SVR rate was influenced by the response to previous PR treatment,the RVR and liver stiffness. | Delphine Bonnet Matthieu Guivarch Anais Palacin Laurent Alric Emilie Bérard Jean-Marc Combis Andre Jean Remy Andre Glibert Jean-Louis Payen Sophie Metivier Karl Barange Herve Desmorat Florence Nicot Florence Abravanel | 2014 | World Journal of Hepatology2014，6，9： | 1 |
| 12 | Fast estimation of localized plasticity and damage by energetic methods 显示文摘 | Desmorat R | 2002 | International Journal of Solids and Structures2002，39，： | 1 |
| 13 | Mullins Effect and Cyclic Stress Softening of Filled Elastomers by Internal Sliding and Friction Thermodynamics Model显示文摘 | Cantournet S Desmorat R Besson J | 2009 | International Journal of Solids and Structures2009，46，1112： | 1 |
| 14 | Incidence of large oesophageal varices in patients with cirrhosis: application to prophylaxis of first bleeding显示文摘 | Cales P Desmorat H Vinel JP | 1990 | Gut1990，31，11： | 1 |
| 15 | Nonlocal Anisotropic Damage Model and Related Computational Aspects for Quasi-brittle Materials显示文摘 | Desmorat R Gatuingt F Ragueneau F | 2007 | Engineering Fracture Mechanics2007，74，： | 1 |
| 16 | Anisotropic damage law of evolution显示文摘 | LEMAITRE J DESMORAT R SAUZAY M | | 0，，02： | 1 |
| 17 | Two scale damage model and related numerical issues for thermo-mechanical high cycle fatigue 显示文摘 | DESMORAT R KANE A SEYEDI M | 2007 | European Journal of Mechanics: A/Solids2007，26，6： | 1 |
| 18 | Nonlocal anisotropic damage model and related computational aspects for quasi-brittle materials显示文摘 | Desmorat R Gatuingt F Ragueneau F | 2007 | Engineering Fracture Mechanics2007，74，4： | 1 |
| 19 | A two scale damage concept applied to fatigue显示文摘 | LEMAITRE J SERMAGE J P DESMORAT R | 1999 | International Journal of Fracture1999，97，1： | 1 |
| 20 | A two scale damage concept applied to fatigue显示文摘 | J. Lemaitre J.P. Sermage R. Desmorat | 1999 | International Journal of Fracture1999，，1： | 1 |
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