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| 1 | Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients显示文摘AIM: To investigate the effect of omega-3 fatty acid parenteral supplementation postoperatively on clinical outcomes and immunomodulation in colorectal cancer patients. METHODS: Forty-two patients undergoing radical colorectal cancer resection with an indication for total parenteral nutrition postoperatively were enrolled in this prospective, double-blind, randomized, controlled study. Patients received total parenteral nutrition supplemented with either soybean oil (LCT; Intralipid, Fresenius-Kabi, SO group, n = 21) or a combination of omega-3 fish oil and soybean oil (LCT:fish oil = 5:1, fish oil; Omegaven, Fresenius-Kabi, FO group, n = 21), up to a total of 1.2 g lipid/kg per day for 7 d postoperatively. A same volume calorie and nitrogen was administrated. Routine blood test, biochemistry, systemic levels of IL-6 and TNF-α, percentage of CD3+, CD4+, and CD8+ lymphocytes were evaluated preoperatively and on postoperative d 1 and 8. Patient outcome was evaluated considering mortality during the hospital stay, length of postoperative hospital stay, and occurrence of infectious complications. RESULTS: Both lipid regimens were well tolerated. No differences between the two groups were noticed in demographics, baseline blood test, biochemistry, serum levels of IL-6 and TNF-α, percentage of CD4+, CD8+ lymphocytes, and ratios of CD4+/CD8+. Compared with those on postoperative d 1, serum IL-6 levels onpostoperative d 8 were significantly depressed in the FO group than in the reference group (-44.43 ± 30.53 vs -8.39 ± 69.08, P = 0.039). Simultaneously, the ratios of CD4+/CD8+ were significantly increased in the FO group (0.92 ± 0.62 vs 0.25 ± 1.22, P = 0.035). In addition, depression of serum TNF-α levels (-0.82 ± 2.71 vs 0.27 ± 1.67, P = 0.125) and elevation of CD3+ and CD4+ lymphocyte percentage (12.85 ± 11.61 vs 3.84 ± 19.62, P = 0.081, 17.80 ± 10.86 vs 9.66 ± 17.55, P = 0.084, respectively) were higher in the FO group than in the reference group. Patients in the FO group trended to need a shorter postoperative hospital stay (17.45 ± 4.80 d vs 19.62 ± 5.59 d, P = 0.19). No statistically significant difference was found when stratified to mortality and occurrence of infectious complications. CONCLUSION: Postoperative supplementation of omega-3 fatty acids may have a favorable effect on the outcomes in colorectal cancer patients undergoing radical resection by lowering the magnitude of inflammatory responses and modulating the immune response. | Bin Liang, Shan Wang, Ying-Jiang Ye, Xiao-Dong Yang, You-Li Wang, Jun Qu, Qi-Wei Xie, Mu-Jun Yin, Division of Surgical Oncology and Division of Gastroenterological Surgery, Peking University People’s Hospital, Beijing 100044, China Author contributions: Liang B and Wang S contributed equally to this work Liang B and Wang S designed the research Liang B, Ye YJ, Yang XD, Wang YL, Qu J, Xie QW, Yin MJ performed the research and collected the data Wang S and Ye YJ supervised the research Liang B and Ye YJ analyzed the data Liang B wrote the paper and revised the manuscript. | 2008 | World Journal of Gastroenterology2008，14，15： | 31 |
| 2 | Motion behavior of particles in air-solid magnetically stabilized fluidized beds for separation显示文摘In order to study the settling mechanism of particles in an air-solid magnetically stabilized fluidized bed(MSFB) for separation,we carried out free settling and quasi-zero settling tests on the tracing particles.The results show that the main resistance forces as the tracing particles settled in an air-solid MSFB were motion resistance force and yield force.The motion resistance and yield forces greatly hindered the free settling of the particles by greatly decreasing the acceleration for settling process of the particles.The acceleration decreased from 3022.62 cm/s 2 to zero in 0.1 s,and in the end,the particles stopped in the air-solid MSFB.The yield force on particles increased with increasing the magnetic field intensity,resulting in decrease of the quasi-zero settling displacement.However,the yield force on particles decreased with increasing the fluidized air velocity,leading to increase of the quasi-zero settling displacement.When the structure and operating parameters of the air-solid MSFB were set up,the yield stress on particles stopped in an air-solid MSFB was a function of diameter and density of particles.The settling displacements of equal diameter particles increased with increasing their densities,and the settling displacements of equal density particles increased with increasing their diameters. | Song Shulei a,,Zhao Yuemin a,Luo Zhenfu a,Tang Ligang b a School of Chemical Engineering and Technology,China University of Mining & Technology,Xuzhou 221116,China b Coal Mining and Designing Department,Tiandi Science & Technology Company Co.Ltd.,Beijing 100013,China | 2012 | International Journal of Mining Science and Technology2012，22，5： | 13 |
| 3 | Coupled modeling of tumour angiogenesis, tumour growth,and blood perfusion显示文摘This paper proposes a more realistic mathematical simulation method to investigate the dynamic process of tumour angio-genesis by fully coupling the vessel growth,tumour growth and associated blood perfusion.The tumour growth and angiogenesis are coupled by the chemical microenvironment and the cell-matrix interaction.The haemodynamic calculation is carried out on the new vasculature,and an estimation of vessel collapse is made according to the wall shear stress criterion.The results are consistent with physiological observations,and further confirm the application of the coupled model feedback mechanism.The model is available to examine the interactions between angiogenesis and tumour growth,to study the change in the dynamic process of chemical environment and the vessel remodeling. | Y.Cai,1,2 S.X.Xu,1,a) J.Wu,3 and Q.Long 2,b) 1) Department of Mechanics and Engineering Science,Fudan University,Shanghai 200433,China 2) Brunel Institute for Bioengineering,School of Engineering and Design,Brunel University,Uxbridge,Middlesex,UK 3) School of Naval Architecture,Ocean and Civil Engineering,Shanghai Jiaotong University,Shanghai 200240,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，4： | 8 |
| 4 | Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility:A meta-analysis显示文摘AIM: To assess the association between Interleu-kin-10 (IL-10) gene IL-10-1082 (G/A), IL-10-592(C/A), IL-10-819 (T/C) polymorphisms and hepatocellular carcinoma (HCC) susceptibility.METHODS: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure, and Chinese Biomedicine Database. Summary odds ratios (ORs) and 95% conf idence intervals (95% CIs) for IL-10 polymorphisms and HCC were cal-culated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. RESULTS: This meta analysis included seven eligiblestudies, which included 1012 HCC cases and 2308 controls. Overall, IL-10-1082 G/A polymorphism was not associated with the risk of HCC (AA vs AG + GG, OR = 1.11, 95% CI = 0.90-1.37). When stratifying for ethnicity, the results were similar (Asian, OR = 1.12, 95% CI = 0.87-1.44; non-Asian, OR = 1.10, 95% CI = 0.75-1.60). In the overall analysis, the IL-10 polymorphism at position -592 (C/A) was identified as a genetic risk factor for HCC among Asians; patients carrying the IL-10-592*C allele had an increased risk of HCC (OR = 1.29, 95% CI = 1.12-1.49). No association was observed between the IL-10-819 T/C polymorphism and HCC susceptibility (TT vs TC + CC, OR = 1.02, 95% CI = 0.79-1.32).CONCLUSION: This meta-analysis suggests that IL-10-592 A/C polymorphism may be associated with HCC among Asians. IL-10-1082 G/A and IL-10-819 T/C polymorphisms were not detected to be related to the risk for HCC. | Yong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin YangYong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin Yang, Department of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Prov- ince, China Author contributions: Wei YG and Liu F designed the study, collected and analyzed the data and wrote the manuscript Li B collected and analyzed the data and wrote the manuscript Chen X and Ma Y collected and analyzed the data Yan LN analyzed the data and contributed to the discussion Wen TF and Xu MQ revised the manuscript Wang WT and Yang JY contributed to the discussion Wei YG and Liu F contributed equally to this work. | 2011 | World Journal of Gastroenterology2011，17，34： | 3 |
| 5 | Influence of precipitation on the Portevin-Le Chatelier effect in Al-Mg alloys显示文摘In the alloy with solute content higher than the limiting solubility,the solute atoms that have failed to dissolve will precipitate from the solid solution and form precipitations.In this study, the Portevin-Le Chatelier(PLC) effects in annealed 5456 and 5052 aluminum alloys with different precipitation contents have been investigated under different applied strain rates.The results suggest that precipitations have significant effect on the PLC effect and the more the precipitations are, the greater the ... | Qi Hu,~(a))Qingchuan Zhang,~(b)) Shihua Fu,Pengtao Cao,and Ming Gong CAS Key Laboratory of Mechanical Behavior and Design of Materials,University of Science and Technology of China,Hefei 230027,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，1： | 3 |
| 6 | The service experience intourism 显示文摘 | Herbert M Design Review Seductive objectswith a wly sting Ritchie B J | 1996 | Tourism Management1996，17，3： | 1 |
| 7 | Documenting the staff perceptions of open ward family room units显示文摘 | Domanico R Davis D K Coleman NICU design versus single 30 (5) : 34 dilemma: Parent and F Davis B O | 2010 | Journal of Perinatology2010，3351，： | 1 |
| 8 | Emitter and current handling capability of AIGaAs/GaAs power heterojunction bipolar transistors 显示文摘 | GAOG B UNLU M S MORKOC ballasting resistor design for H | 1991 | IEEE Transactions on Electron Devices1991，38，2： | 1 |
| 9 | Robust H2/Hoo global for nonlinear stochastic systems显示文摘 | Chen B S Chen W Wu linearization filter design H | 2009 | IEEE Trans on Circuits and Systems- I2009，56，7： | 1 |
| 10 | implementation of a new hyperchaotic system显示文摘 | Guang-Yi W B Xu-Lei and W Zhong-Lin Design and FPGA | 2008 | Chinese Physics B2008，17，10： | 1 |
| 11 | The benefits and costs of riparian analysis habitat preservation:A willingness to accept/willingness to pay using contingent valuation approach显示文摘 | Amigues J P Boulat off C Designes B | 2002 | Ecological Economics2002，43，： | 1 |
| 12 | -Part IT显示文摘 | Cox E Martin B van Staa T Good research practices forcomparative effectiveness research: approaches to mitigate biasand confounding in the design of non-randomized studies of treatment effects using secondary data sources | 2009 | Value Health2009，12，： | 1 |
| 13 | and differential expression analysis of small RNA sequencing experiments 显示文摘 | McCormick K P Willmann M R Meyers B C Experimental design preprocessing normalization | 2011 | Silence2011，，2： | 1 |
| 14 | Guaranteed cost fault-tolerant controller period sa 2009,8(4 f networked control systems under variable- mpling显示文摘 | Li X design Wu X B | 2009 | Information Technology Journal2009，，： | 1 |
| 15 | 栖居自然显示文摘德国诗人荷尔德林有一首诗名为《人,诗意地栖居》,意在呼唤人们回归自然,重拾心灵的自由。我想,“诗意地栖居”并非一定要真正生活在自然之中,诗人更多的是倡导一种朴素的追求,维守心灵的沉静吧。即使身处藩篱,也仍然要怀抱诗意的向往。而对生活在繁忙都市的我们来说,回到家,有那么一个宁静安稳的避风港停靠,就是对我们一天疲累最好的抚慰。栽一株花,逗一只鸟,当心灵完全卸下了负载,大概也算一种“诗意地栖居”了。 | Eva Solo Rebob Sidai Designs Studio Macura Batrice Bruneteau Daevas Design ALEXANDRA HAJEK Alan Wisniewski Eugnie DeLoynes Ryosuke Fukusada Ontwerpduo Nitin Barchha & Disney Davis Taeg Nishimoto Luca Nichetto Front Satyendra Pakhal Zara 彭佳 | 2016 | 现代装饰(家居)2016，0，10： | 0 |
| 16 | 父爱如山显示文摘罗中立最著名的油画《父亲》以浓厚的油彩和西方现代艺术中超写实的手法,巧妙地采用特写构图塑造了一幅感情真挚、纯朴憨厚的父亲画面。那饱经沧桑黑沉沉的脸庞、深邃忧郁藏着无言悲哀的眼睛、古松皮似宽大粗糙的双手感动了无数的欣赏者。 | Bttcher+Henssler Edmire Giulio Iacchetti j-me Knud Holscher Mukul Goyal Marcantonio Raimondi Malerba Norm Architects Sφren Refsgaard Simon Stevens Tom Stepp Troels Seidenfaden Tools Design Yu-Fen LO 伏平 | 2014 | 现代装饰(家居)2014，，6： | 0 |
| 17 | SYNTHESIS OF AZA-CROWN-ETHER CHOLESTERIC LIQUID CRYSTALS显示文摘Five aza-crown-ethers were synthesized and four of them shown to have cholesteric liquid crystalline properties. Their properties relevant to cholesteric liquid crystal were determined by DSC and the textures. The type of cholesteric mesomorphic azacrown ether have not been reported so far. | Ming Gui XIE~a,Shi Kui LIU~b, Gang LIU~c and Jiang Ling LI~d ~aDepartment of Chemistry, Sichuan University, Chengdu, 610064. ~bChengdu Institute of Organic Chemistry, Academia Sinica, 610015. ~cChengdu Institute of Chemical Engineering Research and Design, Chengdu, 610061 ~dEnviromental Monitoring Station of Wuhou District, Chengdu, 610041. | 1992 | Chinese Chemical Letters1992，3，10： | 0 |
| 18 | 慢生活显示文摘城市的迅速发展使得人们的生活节奏越来越快,但生活的最终目的还是为了寻求快乐,而“快乐”是否是“快”即能“乐”这么简单?大城市的生活总是忙忙碌碌的,似乎没有让人停下来的时间。突然忆起几年前的一部香港影片《月满轩尼诗》,导演岸西在访谈中曾说到,她要在这部影片中拍出勤奋拼搏之外的香港闲人、懒人,更要拍出相比大陆已经“慢下来了”的香港。 | BLOOMA B&B Italia DAMIEN URVOY Patricia Urquiola Pavel Vetrov Redo Design Studio Sara Elizagarate Nogales Dorja Benussi Maryia Virshych Yonoh Estudio Creativo Alegre Design Muka Design Lab 李薇 范嘉苑 | 2015 | 现代装饰(家居)2015，0，8： | 0 |
| 19 | 器物的温度显示文摘当生活中满足机器批量生产的完美器物时,我们似乎越发怀念匠人们手工制作的物件,虽然有时会有一些小瑕疵,但它们却更具有情感和温度。或许是陶器与瓷器与生俱来的质感,又或许是它们的制作过程需要经过高温的烧制,一直觉得隐患和瓷器是最具温度的两种器物类型。 | nendo GANDIABLASCO Something Like This Design FRG & BLANCHE Sebastian Herkner Ewelina Wisniowska Ragnhild Finsveen Liven Maren Sjaaholm Knudsen Cristian Heikoop BEKA SUOMU DESIGN Daniel Debiasi & Federico Sandri Jeanne Bonnefoy Mercuriali Dimitri Bhler 李薇 范嘉苑 | 2016 | 现代装饰(家居)2016，0，12： | 0 |
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