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129篇 您的检索式:作者名="Dee P"
    题名 作者 年代 出处 被引量
1Rho A signaling and blood pressure: The consequence of failing to “Tone it Down”显示文摘Uncontrolled high blood pressure is a major risk factor for heart attack, stroke, and kidney failure and contributes to an estimated 25% of deaths worldwide. Despite numerous treatment options, estimates project that reasonable blood pressure(BP) control is achieved in only about half of hypertensive patients. Improvements in the detection and management of hypertension will undoubtedly be accomplished through a better understanding of the complex etiology of this disease and a more comprehensive inventory of the genes and genetic variants that influence BP regulation. Recent studies(primarily in pre-clinical models) indicate that the small GTPase Rho A and its downstream target, Rho kinase, play an important role in regulating BP homeostasis. Herein, we summarize the underlying mechanisms and highlight signaling pathways and regulators that impart tight spatial-temporal control of Rho A activity. We also discuss known allelic variations in the Rho A pathway and consider how these polymorphisms may affect genetic risk for hypertension and its clinical manifestations. Finally, we summarize the current(albeit limited) clinical data on the efficacy of targeting the Rho A pathway in hypertensive patients.Xue Bai Rachel Dee Kevin D Mangum Christopher P Mack Joan M Taylor 2016World Journal of Hypertension2016,6,1:3
2Effect of vaccination with a modified-live porcine reproductive and respiratory syndrome virus vaccine on dynamics of homologous viral infection in pigs显示文摘Cano J P Dee S A Murtaugh M P 2007Am J Vet Res2007,68,:1
3Predictors of complications after endoscopic retrograde cholangiopancreatography: a prognostic model for early discharge显示文摘Jeurnink S M Siersema P D Steyerberg E W Dees J Poley J W Haringsma J 2011Surg Endosc2011,25,:1
4Mal-aligning humeral offset may not effect shoulder:a biomechanical study显示文摘McMahon P J Dee D T Yang B Y 2003Med Sci Monit2003,9,8:1
5Microbial diversit y in hot synthetic compost as revealed by PCR-Amplified rRNA sequences from cultivated isolates and extracted DNA显示文摘Peter M Dees P M Ghiorse W C 2001FEMS Microbiology Ecology2001,35,2:1
6The ERA - Interim reanalysis: configuration and performance of the data assimilation system显示文摘Dee D P Uppala S M Simmons A J 2011Q J R Meteorol Soc2011,137,:1
7Simplification of the Kalman filter for meteorologicald ata assimilation显示文摘Dee D P 1991Quarterly Journal of the Royal Meteorological Society1991,117,:1
8Microbial diversity in hot synthetic compost as revealed by PCR-amplified rRNA sequences from cultivated isolates and extracted DNA 显示文摘Dees P Ghiorse W 2001FEMS Microbiology Ecology2001,35,2:1
9Fluoroscopic and compu- ted tomographic features of the pharyngeal airway in obstructive sleep apnea显示文摘Suratt PM Dee P Atkinson RL 1983Am Rev Respir Dis1983,127,4:1
10Slope-dependent friction in a barotropic model显示文摘Dees K Nycander J Sigry P 2004J Geophys Res2004,109,01:1
11Mirobial diversity in hot synthetic compost as revealed by PCR-amplified rRNA sequences from cultivated isolates and extracted DNA显示文摘DEES P M GHIORSE W C 2001FEMS Microbiol Eco2001,35,:1
12Mela- nocyte autologous grafting for treatment of leukoderma 显示文摘Suvanprakom P Dee - Ananlap S Pongsom boon C 1985J Am Acad Dematol1985,13,6:1
13Data assimilation in the presence of forecast bias:The GEOS moisture analysis显示文摘Dee D P Todling R 2000Monthly Weather Review2000,128,9:1
14The ERA-Interim reanalysis: Configuration and performance of the data assimilation system 显示文摘DEE D P UPPALA S M SIMMONS A J 2011Q J R Meteo Soc2011,137,656:1
15Improved delay-range-dependent stability criteria for linear systems wiht time-varying delays 显示文摘Sun J Liu G P Chen J Dees D 2010Automatica2010,46,2:1
16Microbial diversity in hot synthetic compost as revealed by PCRamplified rRNA sequences from cultivated isolates and extracted DNA 显示文摘Dees P M Ghiorse W C 2001FEMS Microbiol Eco2001,35,:1
17Infection dynamics and clin- ical manifestations following experimental inoculation of gilts at 90 days of gestation with a low dose of porcine reproductive and respiratory syndrome virus显示文摘Cano J P Dee S A Murtaugh M P 2009Can J Vet Res2009,73,4:1
18Development of a high-power lithium-ion battery显示文摘JANSEN A N KAHAIAN A J KEPLER K D NELSON P A AMINE K DEES D W VISSERS D R THACKERAY M M 1999Journal of Power Sources1999,8182,:1
19The ERA-Interim reanalysis:configuration and performance of the data assimilation system显示文摘Dee D P Uppala S M Simmons A J 2011Quarterly Journal of the Royal Meteorological Society2011,137,656:1
20Association between thyroid function and metabolic syndrome in elderly subjects 显示文摘Wang JY Wang CY Dee P 2010JAGS2010,58,8:1
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