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| 1 | Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement显示文摘 | David Moher Deborah J Cook Susan Eastwood Ingram Olkin Drummond Rennie Donna F Stroup | 1999 | The Lancet1999,,9193: | 1 |
| 2 | Nosocomail pneumonia and the rate of gastric pH显示文摘 | DEBORAH J COOK MD LOREN A | 1991 | Chest1991,100,1: | 1 |
| 3 | Nosocomail pneumonia and the rad of gastric PH显示文摘 | DEBORAH J COOK MD LOREN A | 1991 | Chest1991,100,1: | 1 |
| 4 | Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?显示文摘 | David Moher Ba’ Pham Alison Jones Deborah J Cook Alejandro R Jadad Michael Moher Peter Tugwell Terry P Klassen | 1998 | The Lancet . 1998 (9128)1998,,9128: | 1 |
| 5 | Stress ulcer prophlaxls in the critically ill:a meta- analysis显示文摘 | Deborah J Cook MD Lana G | 1991 | Am J Med1991,91,5: | 1 |
| 6 | Local linear regression for estimating time series data显示文摘 | Quinton J Nottingham Deborah F Cook | 2001 | Computational Statistics & Data Analysis2001,37,: | 1 |
| 7 | Management of the critically ill patient with severe acute pancreatitis显示文摘 | Avery B. Nathens J Randall Curtis Richard J. Beale Deborah J. Cook Rui P. Moreno Jacques-Andre Romand Shawn J. Skerrett Renee D. Stapleton Lorraine B. Ware Carl S. Waldmann | 2004 | Critical Care Medicine2004,,12: | 1 |
| 8 | Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome 显示文摘 | Marshall JC Deborah J Cook | 1995 | Crit Care Med1995,23,: | 1 |
| 9 | Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients显示文摘 | Sangeeta Mehta Lisa Burry Sandra Fischer J Carlos Martinez-Motta David Hallett Dennis Bowman Cindy Wong Maureen O. Meade Thomas E. Stewart Deborah J. Cook | 2006 | Critical Care Medicine2006,,2: | 1 |
| 10 | Nosocomial pnenumonia and the role of gastric PH显示文摘 | Deborah J Cook MD Loren A | 1991 | Chest1991,100,1: | 1 |
| 11 | Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement显示文摘 | David Moher Deborah J Cook Susan Eastwood Ingram Olkin Drummond Rennie Donna F Stroup | 1999 | The Lancet . 1999 (9193)1999,,9193: | 1 |
| 12 | Nosocomial Pneumonia and therole of gastric pH显示文摘 | Deborah J Cook MD Loren A | 1991 | Chest1991,100,1: | 1 |
| 13 | Nosocomial pneumonia and the role of gastric pH显示文摘 | Deborah J Cook MD Loren A | 1991 | Chest1991,,1: | 1 |
| 14 | Benefit of heparin in peripheral venous and arterial catheters:Systematic review and meta-analysis of randomised controlled trials显示文摘 | Randolph Adrienne G Cook Deborah J Gonzales Calle A | 1998 | British Medical Journal1998,316,7136: | 1 |
| 15 | Pregnancy‐Associated Osteoporosis With a Heterozygous Deactivating LDL Receptor‐Related Protein 5 ( LRP5 ) Mutation and a Homozygous Methylenetetrahydrofolate Reductase ( MTHFR ) Polymorphism显示文摘 | Fiona J Cook Steven Mumm Michael P Whyte Deborah Wenkert | 2014 | J Bone Miner Res2014,,4: | 1 |
| 16 | Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?显示文摘 | David Moher Ba’ Pham Alison Jones Deborah J Cook Alejandro R Jadad Michael Moher Peter Tugwell Terry P Klassen | 1998 | The Lancet1998,,9128: | 1 |
| 17 | Nosocomial pneu- monia and the role of gastric pH显示文摘 | DEBORAH J COOK MD LOREN A | 1991 | Chest1991,100,1: | 1 |
| 18 | Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?显示文摘 | David Moher Ba’ Pham Alison Jones Deborah J Cook Alejandro R Jadad Michael Moher Peter Tugwell Terry P Klassen | 1998 | The Lancet1998,,9128: | 1 |
| 19 | Nosocomial pneumonia and the role of gastric Ph显示文摘 | Deborah J Cook MD Loren A | 1991 | Chest1991,100,1: | 1 |
| 20 | Health-related quality-of-life and health-utility reporting in critical care显示文摘Mortality is a well-established patient-important outcome in critical care studies.In contrast,morbidity is less uniformly reported(given the myriad of critical care illnesses and complications of each)but may have a common end-impact on a patient’s functional capacity and health-related quality-of-life(HRQoL).Survival with a poor quality-of-life may not be acceptable depending on individual patient values and preferences.Hence,as mortality decreases within critical care,it becomes increasingly important to measure intensive care unit(ICU)survivor HRQoL.HRQoL measurements with a preference-based scoring algorithm can be converted into health utilities on a scale anchored at 0(representing death)and 1(representing full health).They can be combined with survival to calculate quality-adjusted life-years(QALY),which are one of the most widely used methods of combining morbidity and mortality into a composite outcome.Although QALYs have been use for health-technology assessment decision-making,an emerging and novel role would be to inform clinical decision-making for patients,families and healthcare providers about what expected HRQoL may be during and after ICU care.Critical care randomized control trials(RCTs)have not routinely measured or reported HRQoL(until more recently),likely due to incapacity of some patients to participate in patient-reported outcome measures.Further differences in HRQoL measurement tools can lead to non-comparable values.To this end,we propose the validation of a gold-standard HRQoL tool in critical care,specifically the EQ-5D-5L.Both combined health-utility and mortality(disaggregated)and QALYs(aggregated)can be reported,with disaggregation allowing for determination of which components are the main drivers of the QALY outcome.Increased use of HRQoL,health-utility,and QALYs in critical care RCTs has the potential to:(1)Increase the likelihood of finding important effects if they exist;(2)improve research efficiency;and(3)help inform optimal management of critically ill patients allowing for decision-making about their HRQoL,in additional to traditional health-technology assessments. | Vincent Issac Lau Jeffrey A Johnson Sean M Bagshaw Oleksa G Rewa John Basmaji Kimberley A Lewis M Elizabeth Wilcox Kali Barrett Francois Lamontagne Francois Lauzier Niall D Ferguson Simon J W Oczkowski Kirsten M Fiest Daniel J Niven Henry T Stelfox Waleed Alhazzani Margaret Herridge Robert Fowler Deborah J Cook Bram Rochwerg Feng Xie | 2022 | World Journal of Critical Care Medicine2022,11,4: | 0 |