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您的检索式：作者名="Deborah Fowler"
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| 1 | Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: Diagnosis and treatment显示文摘 | John Muscedere Peter Dodek Sean Keenan Rob Fowler Deborah Cook Daren Heyland | 2008 | Journal of Critical Care2008，，1： | 1 |
| 2 | Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: Prevention显示文摘 | John Muscedere Peter Dodek Sean Keenan Rob Fowler Deborah Cook Daren Heyland | 2008 | Journal of Critical Care2008，，1： | 1 |
| 3 | Modeling and Measurement of a Tunable Acoustoelastic System显示文摘Acoustoelastic coupling occurs when a hollow structure’s in-vacuo mode aligns with an acoustic mode of the internal cavity.The impact of this coupling on the total dynamic response of the structure can be quite severe depending on the similarity of the modal frequencies and shapes.Typically,acoustoelastic coupling is not a design feature,but rather an unintended result that must be remedied as modal tests of structures are often used to correlate or validate finite element models of the uncoupled structure.Here,however,a test structure is intentionally designed such that multiple structural and acoustic modes are well-aligned,resulting in a coupled system that allows for an experimental investigation.First,coupling in the system is identified using a measure termed the magnification factor.Next,the structural-acoustic interaction is measured.Modifications to the system demonstrate the dependency of the coupling on changes in the mode shape and frequency proximity.This includes an investigation of several practical techniques used to decouple the system by altering the internal acoustic cavity,as well as the structure itself.These results show that acoustic absorption material effectively decoupled the structure while structural modifications,in their current form,proved unsuccessful.Readily available acoustic absorptive material was effective in reducing the coupled effects while presumably adding negligible mass or stiffness to the structure. | Deborah Fowler Garrett Lopp Dhiraj Bansal Ryan Schultz Matthew Brake Micah Shepherd | 2018 | Sound & Vibration2018，52，3： | 0 |
| 4 | Health-related quality-of-life and health-utility reporting in critical care显示文摘Mortality is a well-established patient-important outcome in critical care studies.In contrast,morbidity is less uniformly reported(given the myriad of critical care illnesses and complications of each)but may have a common end-impact on a patient’s functional capacity and health-related quality-of-life(HRQoL).Survival with a poor quality-of-life may not be acceptable depending on individual patient values and preferences.Hence,as mortality decreases within critical care,it becomes increasingly important to measure intensive care unit(ICU)survivor HRQoL.HRQoL measurements with a preference-based scoring algorithm can be converted into health utilities on a scale anchored at 0(representing death)and 1(representing full health).They can be combined with survival to calculate quality-adjusted life-years(QALY),which are one of the most widely used methods of combining morbidity and mortality into a composite outcome.Although QALYs have been use for health-technology assessment decision-making,an emerging and novel role would be to inform clinical decision-making for patients,families and healthcare providers about what expected HRQoL may be during and after ICU care.Critical care randomized control trials(RCTs)have not routinely measured or reported HRQoL(until more recently),likely due to incapacity of some patients to participate in patient-reported outcome measures.Further differences in HRQoL measurement tools can lead to non-comparable values.To this end,we propose the validation of a gold-standard HRQoL tool in critical care,specifically the EQ-5D-5L.Both combined health-utility and mortality(disaggregated)and QALYs(aggregated)can be reported,with disaggregation allowing for determination of which components are the main drivers of the QALY outcome.Increased use of HRQoL,health-utility,and QALYs in critical care RCTs has the potential to:(1)Increase the likelihood of finding important effects if they exist;(2)improve research efficiency;and(3)help inform optimal management of critically ill patients allowing for decision-making about their HRQoL,in additional to traditional health-technology assessments. | Vincent Issac Lau Jeffrey A Johnson Sean M Bagshaw Oleksa G Rewa John Basmaji Kimberley A Lewis M Elizabeth Wilcox Kali Barrett Francois Lamontagne Francois Lauzier Niall D Ferguson Simon J W Oczkowski Kirsten M Fiest Daniel J Niven Henry T Stelfox Waleed Alhazzani Margaret Herridge Robert Fowler Deborah J Cook Bram Rochwerg Feng Xie | 2022 | World Journal of Critical Care Medicine2022，11，4： | 0 |
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