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| 1 | 中文版急性冠脉综合征反应指数量表信度及效度研究显示文摘目的:评价中文版急性冠脉综合征反应指数量表(C-ACSRI)的信度及效度。方法:采用翻译并修订的C-ACSRI对224例冠心病患者进行调查,并对结果进行信度、效度分析。结果:以Cronbach’sα系数检验总量表及态度、信念分量表的信度,Kuder-Rechardson 20(K-R20)系数检验知识分量表的信度,结果分别为0.81(总量表)、0.79(知识)、0.87(态度)、0.71(信念)。总量表的内容效度指数为0.93;分量表与总量表得分之间的相关系数为0.58~0.82,P<0.01;主成分分析经方差最大正交旋转后,知识分量表抽取2个因子共解释总方差的31.6%,态度、信念分量表抽取3个因子共解释总方差的61.0%。结论:中文版急性冠脉综合征反应指数量表具有良好的信度及效度,可作为临床医务人员和研究人员进行筛查、测量的工具。 | 曹英娟 曹秀玲 娄凤兰 高晖 刘庆红 Patricia M Davidson | 2013 | 中国护理管理2013，13，5： | 4 |
| 2 | Haemoxygenase modulates cytokine induced neutrophil chemoattractant in hepatic ischemia reperfusion injury显示文摘AIM To investigate the hepatic microcirculatory changes due to Haemoxygenase(HO),effect of HO inhibition on remote ischemic preconditioning(RIPC) and modulation of CINC.METHODS Eight groups of animals were studied- Sham,ischemia reperfusion injury(IRI) the animals were subjected to 45 min of hepatic ischemia followed by three hours of reperfusion,RIPC(remote ischemic preconditioning) + IRI group,remote ischemic preconditioning in sham(RIPC + Sham),PDTC + IR(Pyridodithiocarbamate,HO donor),Zn PP + RIPC + IRI(Zinc protoporphyrin prior to preconditioning),IR-24(45 min of ischemia followed by 24 h of reperfusion),RIPC+IR-24(preconditioning prior to. After 3 and 24 h of reperfusion the animals were killed by exsanguination and samples were taken. RESULTS Velocity of flow(160.83 ± 12.24 μm/s),sinusoidal flow(8.42 ± 1.19) and sinusoidal perfusion index(42.12 ± 7.28) in hepatic IR were lower(P < 0.05) in comparison to RIPC and PDTC(HO inducer). RIPC increased velocity of flow(328.04 ± 19.13 μm/s),sinusoidal flow(17.75 ± 2.59) and the sinusoidal perfusion index(67.28 ± 1.82)(P < 0.05). PDTC(HO induction) reproduced the effects of RIPC in hepatic IR. PDTC restored RBC velocity(300.88 ± 22.109 μm/s),sinusoidal flow(17.66 ± 3.71) and sinusoidal perfusion(82.33 ± 3.5) to near sham levels. Zn PP(HO inhibition) reduced velocity of flow of RBC in the RIPC group(170.74 ± 13.43 μm/s and sinusoidal flow in the RIPC group(9.46 ± 1.34). Zn PP in RIPC(60.29 ± 1.82) showed a fall in perfusion only at 180 min of reperfusion. Neutrophil adhesion in IR injury is seen in both postsinusoidal venules(769.05 ± 87.48) and sinusoids(97.4 ± 7.49). Neutrophil adhesion in RIPC + IR injury is reduced in both postsinusoidal venules(219.66 ± 93.79) and sinusoids(25.69 ± 9.08)(P < 0.05). PDTC reduced neutrophil adhesion in both postsinusoidal venules(89.58 ± 58.32) and sinusoids(17.98 ± 11.01)(P < 0.05) reproducing the effects of RIPC. Zn PP(HO inhibition) increased venular(589.04 ± 144.36) and sinusoidal neutrophil adhesion in preconditioned animals(121.39 ± 30.65)(P < 0.05). IR after 24 h of reperfusion increased venular and sinusoidal neutrophil adhesion in comparison to the early phase and was significantly reduced by RIPC. Hepatocellular cell death in IRI(80.83 ± 13.03),RIPC + IR(17.35 ± 2.47),and PTDC+IR(11.66 ± 1.17) Zn PP + RIPC + IR(41.33 ± 3.07) reduced hepatocellular death. Zn PP significantly increased hepatocellular death(P < 0.05 PTDC/RIPC vs Zn PP and IR). The CINC cytokine levels in sham(101.32 ± 6.42). RIPC + sham(412.18 ± 65.24) as compared to sham(P < 0.05). Hepatic IR(644.08 ± 181.24)(P < 0.05). RIPC CINC-1 levels in the early phase(401.62 ± 78.56). And PDTC(HO inducer) CINC-1 levels in hepatic IR(413.36 ± 63.06) were significantly lower. HO inhibition in preconditioned animals with Zinc protoporphyrin increased serum CINC levels(521.81 ± 74.9)(P < 0.05). The serum CINC levels were high in the late phase of hepatic IR(15306 ± 1222.04). RIPC reduced CINC levels in the late phase of IR(467.46 ± 26.06),P < 0.05.CONCLUSION RIPC protects hepatic microcirculation by induction of HO and modulation of CINC in hepatic IR. | Niteen Tapuria Sameer Junnarkar Mahmoud Abu-amara Barry Fuller Alexander M Seifalian Brian R Davidson | 2016 | World Journal of Gastroenterology2016，22，33： | 3 |
| 3 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 4 | Posterior interosseous nerve localization within the proximal forearm-a patient normalized parameter显示文摘AIM To provide a 'patient-normalized' parameter in the proximal forearm. METHODS Sixty-three cadaveric upper extremities from thirty-five cadavers were studied. A muscle splitting approach was utilized to locate the posterior interosseous nerve(PIN) at the point where it emerges from beneath the supinator. The supinator was carefully incised to expose the midpoint length of the nerve as it passes into the forearm while preserving the associated fascial connections, thereby preserving the relationship of the nerve with the muscle. We measured the transepicondylar distance(TED), PIN distance in the forearm's neutral rotation position, pronation position, supination position, and the nerve width. Two individuals performed measurements using a digital caliper with inter-observer and intraobserver blinding. The results were analyzed with the Wilcoxon-Mann-Whitney test for paired samples. RESULTS In pronation, the PIN was within two confidence intervals of 1.0 TED in 95% of cases(range 0.7-1.3 TED); in neutral, within two confidence intervals of 0.84 TED in 95% of cases(range 0.5-1.1 TED); in supination,within two confidence intervals of 0.72 TED in 95% of cases(range 0.5-0.9 TED). The mean PIN distance from the lateral epicondyle was 100% of TED in a pronated forearm, 84% in neutral, and 72% in supination. Predictive accuracy was highest in supination; in all cases the majority of specimens(90.47%-95.23%) are within 2 cm of the forearm position-specific percentage of TED. When comparing right to left sides for TEDs with the signed Wilcoxon-Mann-Whitney test for paired samples as well as a significance test(with normal distribution), the P-value was 0.0357(significance-0.05) indicating a significant difference between the two sides.CONCLUSION This 'patient normalized' parameter localizes the PIN crossing a line drawn between the lateral epicondyle and the radial styloid. Accurate PIN localization will aid in diagnosis, injections, and surgical approaches. | Srinath Kamineni Crystal R Norgren Evan M Davidson Ellora P Kamineni Andrew S Deane | 2017 | World Journal of Orthopedics2017，8，4： | 2 |
| 5 | Protection of the liver by ischemic preconditioning: a review of mechanisms and clinical applications显示文摘 | Koti R S Seifalian A M Davidson B R | 2003 | Dig Surg2003，20，5： | 2 |
| 6 | Comparison of original and modified BCR sequential extraction procedures for the fractionation of copper, iron, lead, manganese and zinc in soils and sediments显示文摘 | Katherine F Mossop Christine M Davidson | 2002 | Analytica Chimica Acta2002，，1： | 2 |
| 7 | Severe Hand, Foot, and Mouth Disease Associated with Coxsackievirus A6 - Alabama, Connecticut, California, and Nevada, November 201 1 - February 2012显示文摘 | McIntyre Mary G Stevens Kelly M Davidson Sherri Pippin Tina Magill Dagny Kulhanjian Julie A Kelly Daniel Greenhow Tara L Salas Maria L Yagi Shigeo Padilla Tasha Berumen Ricardo Glaser Carol Landry Marie Louise Lott Jason Chen Lei Paulson | 2012 | EN2012，，12： | 2 |
| 8 | Impacts and challenges of United States medical students during the COVID-19 pandemic显示文摘The delivery of medical student education has changed rapidly during the coronavirus disease 2019(COVID-19)pandemic.Students in their pre-clinical years have transitioned to online courses and examinations.Students in their clinical years are not permitted on clinical rotations,and face uncertainties in career exploration and the residency application process.Medical students in all stages of training are volunteering and helping their communities.The future presence of COVID-19 throughout the United States is unknown,and medical students are eager to return to their training.This paper outlines current challenges in medical student education and the various responses that have been adopted.We also discuss possible future directions for students through involvement in telemedicine,outpatient clinic visits,and non-respiratory inpatient care tasks as adequate personal protective equipment,COVID-19 testing,and resources become more widely available. | Stacey Rolak Alexis M Keefe Emily L Davidson Prabesh Aryal Sandesh Parajuli | 2020 | World Journal of Clinical Cases2020，8，15： | 2 |
| 9 | Comparison of the efficacy and safety of rosuvastatin versus atorvastatin , simvastatin , and pravastatin across doses (STELLAR * * STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)显示文摘 | Peter H Jones Michael H Davidson Evan A Stein Harold E Bays James M McKenney Elinor Miller Valerie A Cain James W Blasetto | 2003 | The American Journal of Cardiology2003，，2： | 2 |
| 10 | A model for heap bioleaching of chalcocite with heat balance: mesophiles and moderate thermophiles显示文摘 | Leahy M J Davidson M R Schwarz M P | 2007 | Hyclrometallurgy2007，85，1： | 1 |
| 11 | Agency Costs,Ownership Structure and Corporate Governance Mechanisms显示文摘 | Davidson W N | 2003 | Journal of Banking & Finance2003，27，： | 1 |
| 12 | Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein显示文摘 | ERDJUMENT-BROMAGE H DAVIDSON M B | 1993 | Nature1993，362，6422： | 1 |
| 13 | Postprandial hyperglycaemia and cardiovascular complications of diabetes:an update显示文摘 | Davidson J Hanefeld M | 2006 | Nutr Metab Cardiovasc Dis2006，16，： | 1 |
| 14 | RNA polymerase Ⅲ transcribes human microRNAs显示文摘 | Lanier W Davidson B L | 2006 | Nat Struct Mol Biol2006，13，12： | 1 |
| 15 | Microbial biomass as a source of ni-trogen for cereal 显示文摘 | Lthbridge G Davidson M S | 1983 | Soil Biology and Biochemistry1983，15，： | 1 |
| 16 | Proteomics and ovarian cancer: implications for diagnosis and treatment: a critical review of the recent literature显示文摘 | Posadas Edwin M Davidson | 2004 | Curr Opin Oncol2004，16，5： | 1 |
| 17 | Evaluating evidence-based medicine skills during a performance-based examination显示文摘 | Davidson ra Duerson M Romrell L Pauly R Watson rt | 2004 | Acad Med2004，79，3： | 1 |
| 18 | Improved Artificial Feeding System for Rearing the Whitefly Bemisia argentifolii ( Homoptera: Aleyrodidae ) 显示文摘 | DAVIDSON E W FAY M L BLACKMER J | 2000 | Florida Entomologist2000，83，4： | 1 |
| 19 | Efficacy, safety and early response of paliperidone extended-release tablet s ( paliperidone ER ) : results of a 6-week randomized,placebo-controlled study 显示文摘 | DAVIDSON M EMSLEY R KRAMER M | 2007 | Schizophr Res2007，93，123： | 1 |
| 20 | Effects of atracurium on intraocuiar pressure, eye position, and blood pressure in eucapnic and phyocapnic isoflurane-anes- thetized dogs 显示文摘 | Mcmurphy R M Davidson H J Hodgson D S | 2004 | Am J Vet Res2004，65，5： | 1 |
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