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| 1 | Liver transplantation for a giant mesenchymal hamartoma of the liver in an adult: Case report and review of the literature显示文摘Mesenchymal hamartomas of the liver(MHLs) in adults are rare and potentially premalignant lesions, which present as solid/cystic neoplasms. We report a rare case of orthotopic liver transplantation in a patient with a giant MHL. In 2013, a 34-year-old female sought medical advice after a 2-year history of progressive abdominal distention and respiratory distress. Physical examination revealed an extensive mass in the abdomen. Computed tomography(CT) of her abdomen revealed multiple liver cysts, with the diameter of largest cyst being 16 cm × 14 cm. The liver hilar structures were not clearly displayed. The adjacent organs were compressed and displaced. Initial laboratory tests, including biochemical investigations and coagulation profile, were unremarkable. Tumor markers, including levels of AFP, CEA and CA19-9, were within the normal ranges. The patient underwent orthotopic liver transplantation in November 2013, the liver being procured from a 40-year-old man after cardiac death following traumatic brain injury. Warm ischemic time was 7.5 min and cold ischemic time was 3 h. The recipient underwent classical orthotopic liver transplantation. The recipient operative procedure took 8.5 h, the anhepatic phase lasting for 1 h without the use of venovenous bypass. The immunosuppressive regimen includedintraoperative induction with basiliximab and high-dose methylprednisolone, and postoperative maintenance with tacrolimus, mycophenolate mofetil, and prednisone. The recipient's diseased liver weighed 21 kg(dry weight) and measured 41 cm × 32 cm × 31 cm. Histopathological examination confirmed the diagnosis of an MHL. The patient did not experience any acute rejection episode or other complication. All the laboratory tests returned to normal within one month after surgery. Three months after transplantation, the immunosuppressive therapy was reduced to tacrolimus monotherapy, and the T-tube was removed after cholangiography showed no abnormalities. Twelve months after transplantation, the patient remains well and is fulfilling all normal activities. Adult giant MHL is extremely rare. Symptoms, physical signs, laboratory results, and radiographic imaging are nonspecific and inconclusive. Surgical excision of the lesion is imperative to make a definite diagnosis and as a cure. Liver transplantation should be considered as an option in the treatment of a non-resectable MHL. | Jiang Li Jin-Zhen Cai Qing-Jun Guo Jun-Jie Li Xiao-Ye Sun Zhan-Dong Hu David KC Cooper Zhong-Yang Shen | 2015 | World Journal of Gastroenterology2015，21，20： | 3 |
| 2 | Treatment Options for the Infertile Male With Cancer显示文摘 | Lo KC Lipshultz LI | 2005 | Journal of the National Cancer Institute Monographs2005，34，： | 1 |
| 3 | C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation显示文摘 | Mina KC David OM Dennis S | 2001 | Circulation2001，104，： | 1 |
| 4 | Clinical xenotransplantation: the next medical revolution?显示文摘 | Burcin Ekser Mohamed Ezzelarab Hidetaka Hara Dirk J van der Windt Martin Wijkstrom Rita Bottino Massimo Trucco David KC Cooper | 2012 | 2012 (9816)2012，，9816： | 1 |
| 5 | Hormonal Therapy of the Brain-Dead Organ Donor: Experimental and Clinical Studies 显示文摘 | Novitzky D Cooper DP David KC | 2006 | Lippincott Williams & Wilkins2006，82，11： | 1 |
| 6 | Endothelial lipase is synthesized by hepatic and aorta endothelial cells and its expression is altered in apoE-deficient mice显示文摘 | Yu KC David C Kadambi S | 2002 | J Lipid Res2002，45，9： | 1 |
| 7 | C-reactive protein elevation in patients with atrial arrhythmias:inflammatory mechanisms and persistence of atrial fibrillation显示文摘 | Mina KC David OM Dennis S | 2001 | Circulation2001，104，： | 1 |
| 8 | Fibrous polyps of the ureter显示文摘 | Davides KC King LM | 1976 | J Urol1976，115，： | 1 |
| 9 | How many sides does a coin have? A phenomenology of Filipino nur- ses' motivation and attitudes towards geriatric care 显示文摘 | Guzman AB Dangoy R J David KC | 2009 | Educational Gerontology2009，35，3： | 1 |
| 10 | Endothelial lipase is synthesized by hepatic and aorta endothelial cells and its expression is altered in apoE-deficient mice 显示文摘 | Yu KC David C Kadambi S | 2004 | J Lipid Res2004，45，16： | 1 |
| 11 | The Detection of simulated retinoblastoma by using red-reflex testing显示文摘 | Jennifer L David KC | | 0，，01： | 1 |
| 12 | Treatment Options for the Infertile Male With Cancer显示文摘 | David Shin Lo KC Lipshultz LI | 2005 | Journal of the National Cancer Institute Monographs2005，34，： | 1 |
| 13 | Primary leiomyosacoma of the epididymis 显示文摘 | Davides KC King LM Paat F | 1975 | J Urol1975，114，4： | 1 |
| 14 | Acute abdominal pain in children显示文摘 | Alexander KC Leung MB David L | 2003 | Am Faro Phys2003，67，11： | 1 |
| 15 | Thyroid hormone and the stunned myocardium显示文摘 | Dimitri Novitzky David KC Cooper | 2014 | The Journal of Endocrinology2014，23，1： | 1 |
| 16 | C-reactive protein elevation in patients with atrial arrhythmias:inflammatory mechanisms and persistence of atrial fibrillation显示文摘 | Mina KC David OM Dennis S | 2001 | Circulation2001，104，： | 1 |
| 17 | Fibrous Polyps of the Ureter显示文摘 | Davides KC King LM | 1976 | J Urol1976，115，： | 1 |
| 18 | 转基因猪对异种移植的影响研究显示文摘对于器官衰竭的患者来说,器官移植是最好的治疗手段。尽管在过去的50年做了很大的努力,但这个问题仍未完全解决,事实上还有很多新的问题。纵观20世纪,有人尝试用动物器官作为临床移植器官的来源[1-2]。这些动物一般为非人类灵长动物(nonhuman primates,NHPs)。通过一些使用NHPs作为供者的实验发现, | 李涛 David Cooper KC 王毅 | 2016 | 现代医药卫生2016，32，4： | 0 |
| 19 | 德拉库拉:骇人听闻的真相显示文摘一直以来,以吸血鬼为主角的文学和影视作品长盛不衰。这些恐怖但有着迷人魅力、似人非人的'生物'吸引着无数的读者和观众。随着'暮光之城'(The Twilight Saga)系列首部曲《暮色》(Twilight)中文版的推出,这股吸血鬼热潮更是有增无减。那么,吸血鬼究竟是什么?历史上最广为人知的吸血鬼德拉库拉背后又藏着什么恐怖的真相?请看—— | David Johnson KC | 2008 | 疯狂英语(初中天地)2008，，10： | 0 |
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