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| 1 | Assessment of the plug flow and dead volume ratios in a sub-surface horizontal-flow packed-bed reactor as a representative model of a sub-surface horizontal constructed wetland显示文摘 | David Jafet Rodríguez Alcocer Germán Giácoman Vallejos Pascale Champagne | 2011 | Ecological Engineering2011，，： | 2 |
| 2 | Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA显示文摘AIM: To investigate the performance of Gadofluorine P-enhanced magnetic resonance imaging(MRI) on the diagnosis of diabetes in a streptozotocin(STZ)-induced diabetic rat model.METHODS: Fischer 344 rats were treated with STZ.Rats not treated with STZ served as controls. T1-weighted MRI was performed using a 3T scanner before and after the injection of Gd-DOTA or Gadofluorine P(6 diabetic rats, 5 controls). The normalized signal intensity(SI) and the enhancement ratio(ER) of the pancreas were measured at each time point, and the values were compared between the normal and diabetic rats using the Mann-Whitney test. In addition,the values were correlated with the mean islet number.Optimal cut-off values were calculated using a positive test based on receiver operating characteristics.Intrapancreatic Gd concentration after the injection of each contrast media was measured using laser ablation-inductively coupled plasma-mass spectrometry in a separate set of rats(4 diabetic rats, 4 controls for Gadofluorine P; 2, 2 for Gd-DOTA).RESULTS: The normalized SI and ER of the pancreas using Gd-DOTA were not significantly different between diabetic rats and controls. With Gadofluorine P, the values were significantly higher in the diabetic rats than in the control rats 30 min after injection(P < 0.05). The area under the receiver operating characteristic curve that differentiated diabetic rats from the control group was greater for Gadofluorine P than for Gd-DOTA(0.967 vs 0.667, P = 0.085). An increase in normalized SI 30 min after Gadofluorine P was correlated with a decrease in the mean number of islets(r 2 = 0.510, P = 0.014). Intra-pancreatic Gd was higher in rats with Gadofluorine P injection than Gd-DOTA injection(Gadofluorine P vs Gd-DOTA, 7.37 vs 0.00, P < 0.01). A significant difference in the concentration of intrapancreatic Gd was observed between the control and diabetic animals that were sacrificed 30 min after Gadofluorine P injection(control vs diabetic, 3.25 ng/g vs 10.55 ng/g, P < 0.05)CONCLUSION: In this STZ-induced diabetes rat model,Gadofluorine P-enhanced MRI of the pancreas showed high accuracy in the diagnosis of diabetes. | Hye Rim Cho Youkyung Lee Philip Doble David Bishop Dominic Hare Young-Jae Kim Kwang Gi Kim Hye Seung Jung Kyong Soo Park Seung Hong Choi Woo Kyung Moon | 2015 | World Journal of Gastroenterology2015，21，19： | 2 |
| 3 | Assessment of the plug flow and dead volume ratios in a sub-surface horizontal-flow packed-bed reactor as a representative model of a sub-surface horizontal constructed wetland显示文摘 | David Jafet Rodríguez Alcocer Germán Giácoman Vallejos Pascale Champagne | 2011 | Ecological Engineering2011，，： | 1 |
| 4 | Epidemiology of ANCA-associated vasculitis显示文摘 | Ntatsaki E Watts RA David GI | 2010 | Rheum Dis Clin N Am2010，36，3： | 1 |
| 5 | Production of α-1,3-galactosyltransferase knockout Pigs by nuclear transfer cloning显示文摘 | Donna K S Kwang W P Hee T C Julia L G Gi S I Melissa S Aaron B August R Billy N D Clifton N M David B C Robert J H Randall S P | 2002 | Science2002，295，5557： | 1 |
| 6 | Land Use Conflict in Kajiado District,Kenya显示文摘 | Campbell David J Helen Gichohi Albert Mwan- gi Lucy Chege | | 0，，17： | 1 |
| 7 | Plant anticancer agents isolation and structure elucidation of new cytototic quinones from TabebuiaCassinoides显示文摘 | Madhusudan RM David GI Kingsto | 1982 | JNatProd1982，45，5： | 1 |
| 8 | Historical inputs of PCDDs,PCDFs and PCBs to a British Columbia interior lake:the effect of environmental cantrols on pulp mill emissions显示文摘 | Robie WM Michael GI David WP | 1998 | Environ Sci & Technol1998，32，： | 1 |
| 9 | MALDI-TOF MS Study of Aromatic Polybenzoxazole Fibers显示文摘 | Gies Anthony P Hercules David M | 2006 | Macromolecules2006，39，7： | 1 |
| 10 | Sep- aration of C6 paraffins using zeolitic imidazolate frame- works= comparison with zeolite 5A显示文摘 | DAVID P GI~RALD C ANGI~LIQUE S M | 2012 | Industrial g> En gineering Chemistry Research2012，51，12： | 1 |
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