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| 1 | Risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: a study of 1,587 patients显示文摘Objective: The purposes of this study were to identify risk factors for cervical lymph node metastasis and to examine the association between BRAF^(V600E) status and clinical features in papillary thyroid microcarcinoma(PTMC).Methods: A total of 1,587 patients with PTMC, treated in Tianjin Medical University Cancer Institute and Hospital from January2011 to March 2013, underwent retrospective analysis. We reviewed and analyzed factors including clinical results, pathology records, ultrasound results, and BRAF^(V600E) status.Results: Multivariate logistic regression analyses demonstrated that gender(male) [odds ratio(OR) = 1.845, P = 0.000], age(< 45 years)(OR = 1.606, P = 0.000), tumor size(> 6 mm)(OR = 2.137, P = 0.000), bilateralism(OR = 2.011, P = 0.000) and extrathyroidal extension(OR = 1.555, P = 0.001) served as independent predictors of central lymph node metastasis(CLNM).Moreover, CLNM(OR = 29.354, P = 0.000) served as an independent predictor of lateral lymph node metastasis(LLNM). Among patients with a solitary primary tumor, those with tumor location in the lower third of the thyroid lobe or the isthmus were more likely to experience CLNM(P < 0.05). Univariate analyses indicated that CLNM, LLNM, extrathyroidal extension, and multifocality were not significantly associated with BRAF^(V600E) mutation.Conclusions: The present study suggested that prophylactic neck dissection of the central compartment should be considered in patients with PTMC, particularly in men with tumor size greater than 6 mm, age less than 45 years, extrathyroidal extension, and tumor bilaterality. Among patients with PTMC, BRAF^(V600E) mutation is not significantly associated with prognostic factors. For a better understanding of surgical management of PTMC and the risk factors, we recommend multicenter research and long-term follow-up. | Xiangqian Zheng Chen Peng Ming Gao Jingtai Zhi Xiukun Hou Jingzhu Zhao Xi Wei Jiadong Chi Dapeng Li Biyun Qian | 2019 | Cancer Biology & Medicine2019，16，1： | 54 |
| 2 | Prediction of cervical lymph node metastases in papillary thyroid microcarcinoma by sonographic features of the primary site显示文摘Objective: To study the sonographic features of the primary site of papillary thyroid microcarcinoma(PTMC) for the prediction of cervical lymph node metastasis during preoperative diagnosis.Methods: A total of 710 PTMC patients between 2013 and 2016 with a diagnosis of cervical lymph node metastases were reviewed.We analyzed the sonographic features of the PTMC primary site to predict ipsilateral or central lymph node metastases in univariate and multivariate models.The ratio of abutment/perimeter of the PTMC primary site was utilized to evaluate cervical lymph node status.Results: Regarding clinical characteristics, multifocality and extrathyroidal extension were associated with cervical lymph node involvement.In the multivariate regression model, calcification and the abutment/perimeter ratio of lesions were evaluated as independent factors in level Ⅵ, ipsilateral or skip cervical lymph node metastases.The cut-off value of the ratio of abutment/perimeter of the PTMC primary site(25%) was significantly correlated with cervical lymph node metastases(P = 0.000).Conclusions: Independent sonographic features, including lesion size, lesion location, calcification, and the ratio of abutment/perimeter of the primary site, were associated with cervical lymph node metastases in PTMC patients. | Xi Wei Meng Wang Xiaoqing Wang Xiangqian Zheng Ying Li Yi Pan Yueguo Li Jiali Mu Yang Yu Dapeng Li Ming Gao Sheng Zhang | 2019 | Cancer Biology & Medicine2019，16，3： | 22 |
| 3 | Deep Structural Framework and Genetic Analysis of Gold Concentration Areas in the Northwestern Jiaodong Peninsula, China: A New Understanding based on High-Resolution Reflective Seismic Survey显示文摘The gold concentration areas in the northwestern Jiaodong Peninsula constituted an important gold metallogenetic region in Eastern China during the Mesozoic. The deep geological bodies' texture characteristic is important for exploring the resources thoroughly and understanding the metallogenic process. The detailed textures were revealed using high-resolution seismic profiles through the three major ore-controlling structures-Sanshandao fault zone, Jiaojia fault zone and Zhaoping fault zone. This study aims to establish a deep structural framework of this area. Based on their formation mechanism, the fault structures developed in the area can be divided into regional and local fault structures. The structural styles are characterised by superimposing their compressional, strike-slip and extensional multi-stage activities. The crust is cut by vertical structures corresponding to a left-lateral strike-slip fault system on the surface. Nearby these structures are the arc-shape structures formed by multi-stage magma intrusions into the upper crust. Bounded by the Tancheng–Lujiang and Muping–Jimo fault zones, the current Jiaodong block, developed a series of NE-trending strike-slip fault systems, was probably formed by the assemblage of several obliquely aligned blocks. The intensive magmatism and hydrothermal activity between the blocks induced large-scale mineralisation. It provides a new angle of view for understanding the cratonic destruction and large ore-concentration formed during the Mesozoic. | YU Xuefeng SHAN Wei XIONG Yuxin GENG Ke SUN Yuqin CHI Naijie GUO Baokui LI Dapeng LI Hongkui SONG Yingxin YANG Deping | 2018 | Acta Geologica Sinica(English Edition)2018，92，5： | 19 |
| 4 | Recognition on the forming-vanishing process and underlying mechanisms of the hypoxia off the Yangtze River estuary显示文摘On the basis of compiled multidisciplinary historical data in 2006–2007 and incorporation of relevant simulation results and remote sensing data, we performed an in-depth study of the generation and dissipation process of the hypoxic zone and its distribution morphology and structure off the Yangtze River estuary. Based on the hydrological circulation dynamics, reproduction of phytoplankton(leading to the decomposition of organic matter), and other factors, we comprehensively and systematically investigated the generation and dissipation of the hypoxic zone and underlying mechanisms for the seasonal variation in its position, explored the multi-factorial synergistic reactions during the generation and dissipation process of the hypoxic zone, and revealed the controlled mechanism for the morphology and structure of the hypoxic zone's distribution. Our studies indicate that in the winter and spring seasons, the hydrological environment off the Yangtze River estuary provides a water body with relatively low contents of dissolved oxygen(DO), which is the background for the formation of a hypoxic zone. After entering into the summer season, the hypoxic zone gradually develops towards the north and becomes mature. Because of the impact of the terrain, local decomposition of organic matter, and upwelling of the Kuroshio subsurface water in July–August, the hypoxic zone off the Yangtze River estuary exhibits the characteristics of discontinuous distribution in space and has a south and north 'dual-core' structure in the inner continental shelf. In addition, there is a hypoxic core in the eastern outer continental shelf. The degrees of hypoxia vary for different areas; they are strongest overall in the north, next strongest in the south; they are weakest on the outer continental shelf. In summer, the hypoxic zone in the north is related to the northward differentiation of the southern hypoxic zone and results from local development and intensification. In August, the hypoxic zone in the north reaches its peak, and after September, it rapidly retreats southward and disappears because of weakening stratification. In the fall, there is hypoxic zone along the coast of Zhejiang in the south, and there is also a low-DO area to the southwest of Jeju Island, with both zones disappearing rapidly. In addition, the change of dynamic environment also causes the low-DO area of the outer continental shelf to move outward in the fall. The variation in the intensity of the stratification and its cumulative effects as a barrier of vertical DO transportation over long periods of time have a significant impact on the degree of hypoxia in the hypoxic zone. In addition, the seasonal variations in the size of the stratified region, intensity of each current system/water mass, upwelling, front, and high-value area of phytoplankton biomass jointly restrict the extension of the hypoxic zone in the inner continental shelf and latitudinal(south-north direction) movement of its location off the Yangtze River estuary. The combined effect of dynamic factors, such as that of the Kuroshio subsurface water, causes a low-DO core in the outer continental shelf. The bottom cold water to the north of the East China Sea is the dynamic basis for the formation of the low-DO area to the southwest of Jeju Island during the fall season. The special seabed topography and mud area distribution off the Yangtze River estuary have a certain degree of influence on the development of the hypoxic zone. The generation and dissipation of the hypoxic zone and its distribution morphology off the Yangtze River estuary, and seasonal variation of its structure and position are a result of the synergistic effects of various factors. | WEI QinSheng WANG BaoDong CHEN JianFang XIA ChangShui QU DaPeng XIE LinPing | 2015 | Science China Earth Sciences2015，58，4： | 15 |
| 5 | Influence of Weave Structures on the Tribological Properties of Hybrid Kevlar/PTFE Fabric Composites显示文摘The existing research of the woven fabric self-lubricating liner mainly focus on the tribological performance improvements and the service life raised by changing different fiber type combinations, adding additive modification, and performing fiber surface modification. As fabric composites, the weave structures play an important role in the mechanical and tribological performances of the liners. However, hardly any literature is available on the friction and wear behavior of such composites with different weave structures. In this paper, three weave structures (plain, twill 1/3 and satin 8/5) of hybrid Kevlar/PTFE fabric composites are selected and pin-on-flat linear reciprocating wear studies are done on a CETR tester under different pressures and different frequencies. The relationship between the tensile strength and the wear performance are studied. The morphologies of the worn surfaces under the typical test conditions are analyzed by means of scanning electron microscopy (SEM). The analysis results show that at 10 MPa, satin 8/5 performs the best in friction-reduction and antiwear performance, and plain is the worst. At 30 MPa, however, the antiwear performance is reversed and satin 8/5 does not even complete the 2 h wear test at 16 Hz. There is no clear evidence proving that the tensile strength has an influence on the wear performance. So the different tribological performance of the three weave structures of fabric composites may be attributed to the different PTFE proportions in the fabric surface and the different wear mechanisms. The fabric composites are divided into three regions: the lubrication region, the reinforced region and the bonding region. The major mechanisms are fatigue wear and the shear effects of the friction force in the lubrication region. In the reinforced region fiber-matrix de-bonding and fiber breakage are involved. The proposed research proposes a regional wear model and further indicates the wear process and the wear mechanism of fabric composites. | GU Dapeng YANG Yulin QI Xiaowen DENG Wei SHI Lei | 2012 | Chinese Journal of Mechanical Engineering2012，25，5： | 12 |
| 6 | Examples of unusual ionospheric observations by the CSES prior to earthquakes显示文摘The CSES(China seismic electromagnetic satellite) was launched on February 2, 2018 in a circular polar orbit at an altitude of~507 km. One of the main objectives of CSES is to search for and characterize ionospheric perturbations that can be associated with seismic activities, to better understand the generation mechanism of such perturbations. Its scientific payload can measure a broad frequency range of electromagnetic waves and some important plasma parameters. This paper is a first-hand study of unusual observations recorded by the CSES over seismic regions prior to four earthquakes with M >7.0 since the satellite's launch. CSES detectors measured irregularities near the epicenter of these four earthquakes. It is already clear that data from instruments onboard the CSES will be of significant help in studies of characteristics of ionospheric perturbations related to earthquakes and their generation mechanisms. | Rui Yan XuHui Shen JianPing Huang Qiao Wang Wei Chu DaPeng Liu YanYan Yang HengXin Lu Song Xu | 2018 | Earth and Planetary Physics2018，2，6： | 7 |
| 7 | Embedding variable micro-capacitors polydimethylsiloxane for enhancing output of triboelectric nanogenerator in power显示文摘 | Xiaona Xia Jie Chen Hengyu Guo Guanlin Liu Dapeng Wei Yi Xi Xue Wang Chenguo Hu | 2017 | Nano Research2017，10，1： | 7 |
| 8 | Numerical investigation on freeze-drying of aqueous material frozen with pre-built pores显示文摘Freeze-drying of the initially porous frozen material with pre-built pores from liquid material was found experimentally to save drying time by over 30% with an initial saturation being 0.28 compared with the conventional operation with the initial saturation being 1, using mannitol as the solid material. In order to understand the mass and heat transfer phenomena of this novel process, a two-dimensional mathematical model of coupled mass and heat transfer was derived with reference to the cylindrical coordinate system. Three adsorption–desorption equilibrium relationships between the vapour pressure and saturation value namely, power-law, Redhead's style and Kelvin's style equation, were tested. Kelvin's style in exponential form of adsorption equilibrium relation gave an excellent agreement between the model prediction and experimental measurement when the equation parameter, γ, of 5000 was applied. Analyses of temperature and ice saturation profiles show that additional heat needs to be supplied to increase the sample temperature in order to promote the desorption process. Simulation also shows that there is a threshold initial porosity after which the drying time decreased with the increase in the initial porosity. Enhanced freeze-drying is expected to be achieved by simultaneously enhancing mass and heat transfer of the process. | Wei Wang Dapeng Hu Yanqiu Pan Guohua Chen | 2016 | Chinese Journal of Chemical Engineering2016，24，1： | 7 |
| 9 | Demonstration of orbital angular momentum channel healing using a Fabry‐Pérot cavity显示文摘 | Shibiao Wei Dapeng Wang Jiao Lin Xiaocong Yuan | 2018 | Opto-Electronic Advances2018，1，5： | 7 |
| 10 | Study about thermal runaway behavior of high specific energy density Li-ion batteries in a low state of charge显示文摘Lithium-ion batteries are widely used in electric vehicles and electronics, and their thermal safety receives widespread attention from consumers. In our study, thermal runaway testing was conducted on the thermal stability of commercial lithium-ion batteries, and the internal structure of the battery was analyzed with an in-depth focus on the key factors of the thermal runaway. Through the study of the structure and thermal stability of the cathode, anode, and separator, the results showed that the phase transition reaction of the separator was the key factor affecting the thermal runaway of the battery for the condition of a low state of charge. | Shiqiang Liu Tianyi Ma Zhen Wei Guangli Bai Huitian Liu Dapeng Xu Zhongqiang Shan Fang Wang | 2021 | Journal of Energy Chemistry2021，30，1： | 6 |
| 11 | Application system and data description of the China Seismo-Electromagnetic Satellite显示文摘The China Seismo-Electromagnetic Satellite, launched into orbit from Jiuquan Satellite Launch Centre on February 2 nd, 2018, is China's first space satellite dedicated to geophysical exporation. The satellite carries eight scientific payloads including high-precision magnetometers to detect electromagnetic changes in space, in particular changes associated with global earthquake disasters. In order to encourage and facilitate use by geophysical scientists of data from the satellite's payloads, this paper introduces the application systems developed for the China Seismo-Electromagnetic Satellite by the Institute of Crustal Dynamics, China Earthquake Administration;these include platform construction, data classification, data storage, data format, and data access and acquisition. | JianPing Huang XuHui Shen XueMin Zhang HengXin Lu Qiao Tan Qiao Wang Rui Yan Wei Chu YanYan Yang DaPeng Liu Song Xu | 2018 | Earth and Planetary Physics2018，2，6： | 5 |
| 12 | A Thin Cloud Removal Method from Remote Sensing Image for Water Body Identification显示文摘In this paper,a thin cloud removal method was put forward based on the linear relationships between the thin cloud reflectance in the channels from 0.4 μm to 1.0 μm and 1.38 μm.Channels of 0.66 μm,0.86 μm and 1.38 μm were chosen to extract the water body information under the thin cloud.Two study cases were selected to validate the thin cloud removal method.One case was applied with the Earth Observation System Moderate Resolution Imaging Spectroradiometer(EOS/MODIS) data,and the other with the Medium Resolution Spectral Imager(MERSI) and Visible and Infrared Radiometer(VIRR) data from Fengyun-3A(FY-3A).The test results showed that thin cloud removal method did not change the reflectivity of the ground surface under the clear sky.To the area contaminated by the thin cloud,the reflectance decreased to be closer to the reference reflectance under the clear sky after the thin cloud removal.The spatial distribution of the water body area could not be extracted before the thin cloud removal,while water information could be easily identified by using proper near infrared channel threshold after removing the thin cloud.The thin cloud removal method could improve the image quality and water body extraction precision effectively. | ZHENG Wei SHAO Jiali WANG Meng HUANG Dapeng | 2013 | Chinese Geographical Science2013，23，4： | 4 |
| 13 | Estimation of stature by using the dimensions of the right hand and right foot in Han Chinese adults显示文摘The Han Chinese people are the main ethnic group in China and the largest ethnic group in the world.The dimensions of the hands and feet have been successfully used for the estimation of stature.A total of 26,927 healthy adult subjects,comprising 13,221 men and 13,706 women,were recruited.The survey samples were chosen through random cluster sampling.The mean values were significantly higher in men than those in women for all measurements(P<0.001).All the measurements showed a statistically significant correlation with stature(P<0.01).The combination of the right hand length and the right foot length was the best predictor of stature because it had the lowest standard error of estimate.The use of multiple regression equations yielded better results than did the use of linear regression equations.The accuracy of stature prediction ranged from ±4.81 to ±6.39 cm.The present study was of great importance with regards to improving the physical anthropology database of ethnic groups in China. | Xinghua Zhangi Yu Wei Lianbin Zhengi Keli Yu Dapeng Zhao Jinping Bao Yonglan Li Shunhua Lu Huanjiu Xi Guochang Xu Youfeng Wen | 2017 | Science China(Life Sciences)2017，60，1： | 4 |
| 14 | Staged angioplasty versus regular carotid artery stenting in patients with carotid artery stenosis at high risk of hyperperfusion:a randomised clinical trial显示文摘Background and purpose Hyperperfusion(HP)is a devastating complication associated with carotid artery stenting(CAS)or endarterectomy.The efficacy and safety of staged angioplasty(SAP)in patients with CAS at high risk of HP remains unclear.We sought to determine whether SAP is superior to regular CAS in patients with high risk of HP.Methods A randomised,multicentre open-label clinical trial with blinded outcome assessment(STEP)was conducted.Patients with severe carotid stenosis at high risk of HP were randomly assigned(1:1)to the SAP or regular CAS group.The primary endpoint was hyperperfusion syndrome(HPS)and intracerebral haemorrhage(ICH)within 30 days after the procedure.Results From November 2014 to January 2017,a total of 64 patients were enrolled in 11 centres.33 patients were allocated to the SAP group and 31 to the regular CAS group.At 30 days,the rate of primary endpoint was 0.0%(0/33)in the SAP group and 9.7%(3/31)in the regular CAS group(absolute risk reduction(ARR),9.7%;95%CI−20.1% to 0.7%;p=0.11).As one of the secondary endpoints,the incidence of HP phenomenon(HPP)was lower in the SAP group than the regular CAS group(0.0%vs 22.6%,ARR,−22.6%;95% CI−36.8%to−10.2%;p=0.04).Conclusion The rate of HPS and ICH was not significantly lower in SAP group;the extended secondary endpoint of HPP,however,significantly reduced,which suggested that SAP may be a safe and effective carotid revascularisation procedure to prevent HP. | Dapeng Mo Baixue Jia Huaizhang Shi Yaxuan Sun Qingan Liu Chengzhe Fan Jianping Deng Jinglin Yuan Wei Wu Changchun Jiang Guilian Zhang Hanjun Du Ning Ma Feng Gao Xuan Sun Ligang Song Lian Liu Guangge Peng Yongjun Wang Yilong Wang Zhongrong Miao the STEP Study Group | 2021 | Stroke & Vascular Neurology2021，6，1： | 3 |
| 15 | Ultra-low V_(pp)and high-modulation-depth InP-based electro-optic microring modulator显示文摘A modulator is an essential building block in the integrated photonics,connecting the electrical with optical signals.The microring modulator gains much attention because of the small footprint,low drive voltage and high extinction ratio.An ultra-low V_(pp)and high-modulation-depth indium phosphide-based racetrack microring modulator is demonstrated in this paper.The proposed device mainly comprises one racetrack microring,incorporating a semiconductor amplifier,and coupling with a bus waveguide through a multimode interference coupler.Traveling wave electrodes are employed to supply bidirectional bias ports,terminating with a 50-Ω impedance.The on/off extinction ratio of the microring reaches 43.3 dB due to the delicately tuning of the gain.An 11 mV V_(pp),a maximum 42.5 dB modulation depth and a 6.6 GHz bandwidth are realized,respectively.This proposed microring modulator could enrich the functionalities and designability of the fundamental integrated devices. | Dapeng Liu Jian Tang Yao Meng Wei Li Ninghua Zhu Ming Li | 2021 | Journal of Semiconductors2021，42，8： | 3 |
| 16 | Dietary fats suppress the peritoneal seeding of colorectal cancer cells through the TLR4/Cxcl10 axis in adipose tissue macrophages显示文摘Peritoneal carcinomatosis(PC)of colorectal cancer(CRC)is a terminal phase of malignancy with no effective strategies for the prevention of this condition.Here we established PC models in mice by intraperitoneal engraftment of CRC cells and revealed an unexpected role for a high-fat diet(HFD)in preventing metastatic seeding in the visceral fat.Mechanistically,the HFD stimulated the activation of adipose tissue macrophages(ATMs)toward an M1-like phenotype and enhanced ATM tumor phagocytosis in a TLR4-dependent manner.Furthermore,the TLR4–Cxcl10 axis in ATMs promoted T cell recruitment,and M1-like macrophages stimulated T cell activation in tumor-seeded fats.The inhibitory effect of the HFD on tumor seeding was abolished with the ablation of macrophages,inactivation of T cells,or blockade of the TLR4–Cxcl10 axis in macrophages.Finally,we showed that a HFD and conventional chemotherapeutic agents(oxaliplatin or 5-fluorouracil)synergistically improved the survival of tumor-seeded mice.Collectively,our findings demonstrate that peritoneal seeding of CRC can be suppressed by short-term treatment with a HFD in the early phase,providing a novel concept for the management of these patients in the clinic. | Wei Xiang Rongchen Shi Dapeng Zhang Xia Kang Lili Zhang Jing Yuan Xuan Zhang Hongming Miao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 3 |
| 17 | The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages显示文摘Lipid metabolic reprogramming plays an essential role in regulating the progression of colorectal cancer(CRC).However,the effect of lysophosphatidic acid(LPA)metabolism on CRC development is incompletely characterized.Here,we compared the mRNA levels of human CRC tissues to those of paracarcinoma tissues and focused on the notably enriched LPA metabolic pathways.We identified and verified that 1-acylglycerol-3-phosphate O-acyltransferase 4(Agpat4)was aberrantly expressed in CRC tissues and predicted poor survival in CRC patients.Manipulating Agpat4 expression in CRC cells did not affect the growth or migration of CRC cells in vitro,whereas Agpat4 silencing suppressed CRC cell growth in subcutaneous and peritoneal xenograft models.Mechanistically,Agpat4 silencing-induced LPA release from CRC cells and polarized macrophages to an M1-like phenotype through LPA receptors 1 and 3.This M1 activation,characterized by elevated p38/p65 signaling and increased proinflammatory cytokines,promoted the infiltration and activation of CD4+and CD8+T cells in the tumor microenvironment.Modulation of the Agpat4/LPA/p38/p65 axis regulated macrophage polarization,T-cell activity and CRC progression.Notably,combined therapy with LPA and regular chemotherapy drugs synergistically suppressed CRC development.Taken together,our results showed that the Agpat4/LPA axis in CRC cells regulated p38/p65 signaling-dependent macrophage polarization,T-cell activation,and CRC progression.The Agpat4/LPA/p38/p65 axis might represent a potential target for therapy in the clinic. | Dapeng Zhang Rongchen Shi Wei Xiang Xia Kang Bo Tang Chuan Li Linfeng Gao Xuan Zhang Lili Zhang Rongyang Dai Hongming Miao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 3 |
| 18 | Hand preference during bimanual coordinated task in northern pig-tailed macaques Macaca leonina显示文摘 | Dapeng ZHAO Yuan WANG Xueyan WEI | 2016 | Current Zoology2016，62，4： | 3 |
| 19 | Double-induced-mode integrated triboelectric nanogenerator based on spring steel to maximize space utilization显示文摘综合 multilayered 摩擦电 nanogenerators (TENG ) 是一条有效途径解决单人赛分层的 TENG 为完成高产量力量密度引起的不够的精力问题。然而,很综合的 multilayered TENG 有相对大的体积。这里,综合摩擦电 nanogenerator (DI-TENG ) 基于春天钢盘子表现为的 double-induced-mode 为收获的周围的颤动精力的一台划算、简单、高效的设备。唯一的可堆迭的菱形结构,在弹簧,钢盘子骨骼充当并且作为电极,能提高输出性能并且最大化空格利用。有五的 DI-TENG 在 12 厘米物浥湥?景愠氠睯漠敶灲瑯湥楴污漠?的体积重复了单位??噭琠?捡楨癥??‰?敬畣慬?敤潳灲楴湯?硅数楲敭瑮污祬洠慥?敲?楤晦牥湥楴污眠牯?畦据楴湯愠??畦据楴湯漠?整灭牥瑡牵?桳睯?敤潳灲楴湯瀠慥獫愠??愠摮????桴楥?汥'虪罐嫖蹫u潲数瑲敩?桳睯朠敲瑡瀠瑯湥楴污映牯爠慥?楴敭?湩猠瑩?潭楮潴楲杮漠?潭敬畣慬?摡潳灲楴湯愠摮搠獥牯瑰潩??瑬潨杵?桴?潭敬畣慬?摡潳灲楴湯椭摮'讚涌畺{?湩琠敨攠敬瑣潲楮?潷歲映湵瑣潩?獩瘠牥?敳獮瑩癩?椠?潤獥渠瑯栠癡?湡?...?睯癥牥?桴?整灭牥瑡牵?敤数摮湥祣漠?桴? | Guanlin Liu Hengyu Guo Lin Chen Xue Wang Dapeng Wei Chenguo Hu | 2016 | Nano Research2016，9，11： | 2 |
| 20 | Identifying the Optimal Age for Herpes Zoster Vaccination—Yichang City,Hubei Province,China,2017–2019显示文摘Summary What is already known about this topic?Herpes zoster(shingles)is a common skin condition in older adults,which usually presents as a painful rash with blisters.Vaccination is the most effective method to prevent shingles.However,there is not sufficient population-based epidemiological data in China to optimize the timing of zoster vaccination.What is added by this report?Clustering analyses of population-wide epidemiological data from the Healthcare Big Data Platform in Yichang,China showed that the average annual zoster incidence is the highest among people 55 years or older,at 10 cases per thousand persons per year,making this age group the optimal target population for vaccination.Incidence was lower but increased with age among younger adults,28–54 years old.What are the implications for public health practice?With limited vaccination resources,zoster vaccinations should be targeted at adults 55 years or older who are at the greatest risk for shingles.Research should be conducted to understand the risk of shingles among young and middle-aged adults and identify triggers of shingles:potentially leading to preventive measures. | Meiying You Tianqi Wang Miaomiao Wang Wei Jiang Jing Jiang Xudong Li Yuehua Hu Dapeng Yin | 2022 | China CDC weekly2022，4，29： | 2 |
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