|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Identification of a novel HMW glutenin subunit and comparison of its amino acid sequence with those of homologous subunits显示文摘Aegilops tauschii is the donor of the D genome of common wheat (Triticum aestivum). Genetic variation of HMW glutenin subunits encoded by the Glu-1Dt locus of Ae. tauschii has been found to be higher than that specified by the Glu-1D locus in common wheat. In the present note, we report the identification of a novel HMW glutenin subunit, Dy13t, from Ae. tauschii. The newly identified subunit pos-sessed an electrophoretic mobility that was faster than that of the Dy12 subunit of common wheat. The complete ORF of encoding the Dy13t subunit contained 624 codons (excluding the stop codons). The amino acid sequence deduced from the Dy13t gene ORF was the shortest among those of the previ-ously reported subunits derived by the D genome. A further comparison of Dy13t amino acid sequence with those of the subunits characterized from the A, B, D, R genomes of Triticeae showed that the smaller size of the Dy13t subunit was associated with a reduction in the size of its repetitive domain. | YAN Zehong WAN Yongfang LIU Kunfan ZHENG Youliang WANG Daowen | 2002 | Chinese Science Bulletin2002，47，3： | 60 |
| 2 | FIT interacts with AtbHLH38 and AtbHLH39 in regulating iron uptake gene expression for iron homeostasis in Arabidopsis显示文摘铁是为植物生长和开发的一个必要元素。在植物的铁动态平衡紧在 transcriptional 和 posttranscriptional 水平被调整。涉及铁动态平衡的几个 bHLH 抄写因素最近被识别了。然而,他们的规章的机制仍然保持未知。在这个工作,我们证明抄写因素适合与 AtbHLH38 和 AtbHLH39 交往了并且直接在 Arabidopsis 为铁动态平衡授与铁举起基因的表示规定。在 Arabidopsis 原物的酵母二混血儿的分析和短暂表示证明那 AtbHLH38 或 AtbHLH39 交往了与合适,在 Arabidopsis 涉及铁动态平衡的一个中央抄写因素。在酵母房间的 FIT/AtbHLH38 或 FIT/AtbHLH39 的表示激活铁的螯的 reductase (FRO2 ) 和铁的 transporter (IRT1 ) 驾驶的 GUS 表示倡导者。Overexpression 与在变换的工厂的 AtbHLH38 或 AtbHLH39 合适铁举起基因 FRO2 和 IRT1 从的表示导致了到组成。因为 IRT1 蛋白质累积和高铁的螯的 reductase 活动被检测在,进一步的分析表明 FRO2 和 IRT1 没在这些工厂在 posttranscriptional 水平被调整过去在铁缺乏和铁充足下面的表示工厂。在更积累的植物在表示任何一个 AtbHLH38 上比野生型或植物在他们的射击熨的表示上双, AtbHLH39 或合适。我们铁螯的 reductase FRO2 和铁运输的 IRT1 是三个抄写因素的目标和 FRO2 和 IRT1 的抄写的数据支持被 FIT/AtbHLH38 或 FIT/AtbHLH39 的建筑群直接调整。 | Youxi Yuan Huilan Wu Ning Wang Jie Li Weina Zhao Juan Du Daowen Wang Hong-QingLing | 2008 | Cell Research2008，18，3： | 57 |
| 3 | Transgenic expression of MYB15 confers enhanced sensitivity to abscisic acid and improved drought tolerance in Arabidopsis thaliana显示文摘Abiotic stresses cause serious crop losses. Knowledge on genes functioning in plant responses to adverse growth conditions is essential for developing stress tolerant crops. Here we report that transgenic expression of MYB15, encoding a R2R3 MYB transcription factor in Arabidopsis thaliana, conferred hypersensitivity to exogenous abscisic acid (ABA) and improved tolerance to drought and salt stresses. The promoter of MYB15 was active in not only vegetative and reproductive organs but also the guard cells of stomata. Its transcript level was substantially upregulated by ABA, drought or salt treatments. Compared with wild type (WT) control, MYB15 overexpression lines were hypersensitive to ABA in germination assays, more susceptible to ABA-elicited inhibition of root elongation, and more sensitive to ABA-induced stomatal closure. In line with the above findings, the transcript levels of ABA biosynthesis (ABA1, ABA2), signaling (ABI3), and responsive genes (AtADH1, RD22, RD29B, AtEM6) were generally higher in MYB15 overexpression seedlings than in WT controls after treatment with ABA. MYB15 overexpression lines displayed improved survival and reduced water loss rates than WT control under water deficiency conditions. These overexpression lines also displayed higher tolerance to NaCl stress. Collectively, our data suggest that overexpression of MYB15 improves drought and salt tolerance in Arabidopsis possibly by enhancing the expression levels of the genes involved in ABA biosynthesis and signaling, and those encoding the stress-protective proteins. | Zhenhua Ding Shiming Li Xueli An Xin Liu Huanju Qin Daowen Wang | 2009 | Journal of Genetics and Genomics2009，36，1： | 42 |
| 4 | A life support-based comprehensive treatment regimen dramatically lowers the in-hospital mortality of patients with fulminant myocarditis: a multiple center study显示文摘Fulminant myocarditis(FM) has unacceptable high mortality. This study aimed to evaluate the therapeutic efficacy of a life support-based comprehensive treatment regimen(LSBCTR), a completely novel treatment regimen, for FM. A total of 169 FM patients recruited from January 2008 to December 2018 were divided into two groups: patients receiving LSBCTR(81 cases),which includes(i) mechanical life support(positive pressure respiration, intra-aortic balloon pump with or without extracorporeal membrane oxygenation),(ii) immunomodulation therapy using sufficient doses of glucocorticoids and immunoglobulins, and(iii) application of neuraminidase inhibitors, and those receiving conventional treatment(88 cases). The endpoints were in-hospital death and heart-transplantation. Of all the population, 44 patients(26.0%) died in hospitals. Inhospital mortality was 3.7%(3/81) for LSBCTR group and 46.6%(41/88) for traditional treatment(P<0.001). Early application of LSBCTR, mechanical life support, neuraminidase inhibitors, and immunomodulation therapy significantly contributed to reduction in in-hospital mortality. This study describes a novel treatment regimen for FM patients that dramatically reduces inhospital mortality. Its generalization and clinical application will efficiently save lives although further optimization is needed.This study offers an insight that virus infection induced inflammatory waterfall results in cardiac injury and cardiogenic shock and is the therapeutic target. | Sheng Li Shengyong Xu Chenze Li Xiao Ran Guanglin Cui Mengying He Kun Miao Chunxia Zhao Jiangtao Yan Rutai Hui Ning Zhou Yan Wang Jiangang Jiang Jing Zhang Daowen Wang | 2019 | Science China(Life Sciences)2019，62，3： | 43 |
| 5 | Chinese expert consensus statement on the diagnosis and treatment of fulminant myocarditis显示文摘Fulminant myocarditis is primarily caused by infection with any number of a variety of viruses. It arises quickly, progresses rapidly, and may lead to severe heart failure or circulatory failure presenting as rapid-onset hypotension and cardiogenic shock,with mortality rates as high as 50%–70%. Most importantly, there are no treatment options, guidelines or an expert consensus statement. Here, we provide the first expert consensus, the Chinese Society of Cardiology Expert Consensus Statement on the Diagnosis and Treatment of Fulminant Myocarditis, based on data from our recent clinical trial(NCT03268642). In this statement, we describe the clinical features and diagnostic criteria of fulminant myocarditis, and importantly, for the first time,we describe a new treatment regimen termed life support-based comprehensive treatment regimen. The core content of this treatment regimen includes(i) mechanical life support(applications of mechanical respirators and circulatory support systems,including intraaortic balloon pump and extracorporeal membrane oxygenation),(ii) immunological modulation by using sufficient doses of glucocorticoid, immunoglobulin and(iii) antiviral reagents using neuraminidase inhibitor. The proper application of this treatment regimen may and has helped to save the lives of many patients with fulminant myocarditis. | Daowen Wang Sheng Li Jiangang Jiang Jiangtao Yan Chunxia Zhao Yan Wang Yexin Ma Hesong Zeng Xiaomei Guo Hong Wang Jiarong Tang Houjuan Zuo Li Lin Guanglin Cui Section of Precision Medicine Group of Chinese Society of Cardiology,Editorial Board of Chinese Journal of Cardiology &Working Group of Adult Fulminant Myocarditis | 2019 | Science China(Life Sciences)2019，62，2： | 18 |
| 6 | Circulating microRNAs in cardiovascular diseases: from biomarkers to therapeutic targets显示文摘microRNAs (miRNAs ) 是有的保存、短、非编码的 RNA 的一个班重要并且在 posttranscriptional 调整基因表示的有势力能力铺平。在过去的几年里,在心血管的系统的 miRNAs 的异常表达式广泛地被报导了,并且在心开发和各种各样的心血管的疾病的 pathophysiology 的某特殊 miRNAs 的关键角色逐渐地被认出了。最近, miRNAs 富有地并且稳定地在外部循环被介绍,这被发现。这提起了为疾病把传播 miRNAs 用作 biomarkers 的可能性。而且,一些研究证明那传播 miRNAs 可以用作房间房间通讯的新奇细胞外的通信员。这些发现不仅在心血管的系统揭示传播 miRNAs 的功能而且通知发展 miRNAs 治疗学的策略。在这评论,我们从 biomarkers 在许多心血管的疾病讨论传播 miRNAs 的潜在的角色到治疗学的目标清楚地在心血管的系统理解传播 miRNAs 的角色。 | FengWang Chen Chen Daowen Wang | 2014 | Frontiers of Medicine2014，8，4： | 13 |
| 7 | 2018 update of expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI显示文摘East Asians are the most populous race in the world and their health status is an important global issue.Compared with Caucasian populations, East Asian patients have a different benefit/risk ratio when using antithrombotic treatment. Despite this observation, treatment strategies in East Asian patients are mostly based on the American and European guidelines. Despite a lower platelet inhibitory response to clopidogrel, East Asian patients show a similar or even a lower rate of ischemic event occurrence and higher bleeding risk compared with Caucasian patients. For potent P2Y_(12) inhibitors(ticagrelor and prasugrel),East Asian patients have shown less favorable net clinical benefits compared with Caucasian patients,which may be related to differences in pharmacokinetic/pharmacodynamic profiles and therapeutic zone of antiplatelet effect. This updated consensus mainly focuses on state-of-the-art and current controversies in the East Asian population. In addition, when East Asian patients are administered potent P2Y_(12) receptor inhibitors, the strategies and ongoing trials to overcome the related hurdles are discussed. | Yong Huo Young-Hoon Jeong Yanjun Gong Daowen Wang Ben He Jiyan Chen Guosheng Fu Yundai Chen Jianping Li Yi Li Shinya Goto Udaya S.Tantry Paul A.Gurbel Jong-Hwa Ahn Hyo-Soo Kim Myung Ho Jeong Yaling Han Sidney C.Smith Jr. Junbo Ge | 2019 | Science Bulletin2019，64，3： | 12 |
| 8 | Three-step semiquantum secure direct communication protocol显示文摘Quantum secure direct communication is the direct communication of secret messages without need for establishing a shared secret key first.In the existing schemes,quantum secure direct communication is possible only when both parties are quantum.In this paper,we construct a three-step semiquantum secure direct communication(SQSDC)protocol based on single photon sources in which the sender Alice is classical.In a semiquantum protocol,a person is termed classical if he(she)can measure,prepare and send quantum states only with the fixed orthogonal quantum basis{|0,|1}.The security of the proposed SQSDC protocol is guaranteed by the complete robustness of semiquantum key distribution protocols and the unconditional security of classical one-time pad encryption.Therefore,the proposed SQSDC protocol is also completely robust.Complete robustness indicates that nonzero information acquired by an eavesdropper Eve on the secret message implies the nonzero probability that the legitimate participants can find errors on the bits tested by this protocol.In the proposed protocol,we suggest a method to check Eves disturbing in the doves returning phase such that Alice does not need to announce publicly any position or their coded bits value after the photons transmission is completed.Moreover,the proposed SQSDC protocol can be implemented with the existing techniques.Compared with many quantum secure direct communication protocols,the proposed SQSDC protocol has two merits:firstly the sender only needs classical capabilities;secondly to check Eves disturbing after the transmission of quantum states,no additional classical information is needed. | ZOU XiangFu QIU DaoWen | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，9： | 12 |
| 9 | Dissecting and Enhancing the Contributions of High-Molecular-Weight Glutenin Subunits to Dough Functionality and Bread Quality显示文摘Dear Editor, Seed storage proteins (SSPs) are frequently important determinants of crop quality traits (Shewry and Casey,1999).Dissecting and enhancing the genetic contributions of individual SSPs to their target traits are essential for effectively improving crop quality attributes.However,such a task is often difficult to accomplish,because SSPs are frequently expressed from multigene families and exhibit strong allelic variation.Consequently,detailed knowledge of the function of individual SSPs in crop quality trait is still limited.This scenario is well illustrated by high-molecular-weight glutenin subunits (HMWGSs),a complex family of SSPs that are involved in wheat enduse quality through affecting dough functionality (Békés,2012;Rasheed et al.,2014). | Yiwen Li Xuefi An Ran Yang Xiaomin Guo Guidong Yue Renchun Fan Bin Li Zhensheng Li Kunpu Zhang Zhenying Dong Luyan Zhang Jiankang Wang Xu Jia Hong-Qing Ling Aimin Zhang Xiangqi Zhang Daowen Wang | 2015 | Molecular Plant2015，8，2： | 9 |
| 10 | Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world. | Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong | 2022 | Science China(Life Sciences)2022，65，9： | 9 |
| 11 | Wide hybridization:engineering the next leap in wheat yield显示文摘Wide hybridization and chromosome engineering constitute an active and important area of plant biology research. The insights obtained in this field have contributed significantly to the understanding of the structure and function of plant chromosomes and genomes, and to the genetic improvement of many agricultural crops. Owing to well defined genomic relationships, clearly visible metaphase chromosomes, | Dr. Daowen Wang | 2009 | Journal of Genetics and Genomics2009，36，9： | 7 |
| 12 | CRISPR editing-mediated antiviral immunity: a versatile source of resistance to combat plant virus infections显示文摘Virus infection poses a constant threat on global crop productivity.It is estimated that virus diseases account for at least 10% of crop losses worldwide.Development of resistant crops using naturally evolved resistance genes has been a main measure for controlling plant virus epidemics.However,isolation of plant resistance genes is costly and time-consuming.Furthermore,most plant resistance genes are pathogen race-specific,with very few of them being broadly specific (Langner et al.,2018).Consequently,artificial immunity with engineered resistance to virus infections has received substantial research,which includes pathogenderived resistance,introducing single or stacked transgene into crops,and RNA interference (Shepherd et al.,2009).However,these strategies have so far achieved limited success due to narrow availability and/or fitness costs on host plants.Therefore,it is urgent to develop novel and more efficient strategies to combat plant virus infections.Recent breakthrough of CRISPR/Cas-based DNA and RNA editing tools provides a promising direction for engineering artificial immunity to plant viruses.There are now increasing reports demonstrating that CRISPR/Cas systems can be harnessed to develop antiviral immunity in plants with high efficiency and broad specificity (Table S1 in Supporting Information). | Xiang Ji Daowen Wang Caixia Gao | 2019 | Science China(Life Sciences)2019，62，9： | 6 |
| 13 | Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis through inhibi- tion of transforming growth factor 13-induced Smad signaling显示文摘 | Wei Gong* Mengwen Yan Junxiong Chen Sandip Chaugai Chen Chen Daowen Wang | 2014 | Frontiers of Medicine2014，8，4： | 6 |
| 14 | An experiment-library least-squares method on on-line coal element contents analysis显示文摘A new experiment-library least-squares(experiment-LLs) method used in the neutron inelastic-scattering and thermal-capture analysis(NITA) technique for on-line coal analysis was developed,which has significantly decreased the non-linear radiation effects.In this method,sixty samples with preset elemental contents were made,from whose experimental spectra twenty single-element spectrum libraries corresponding to twenty kinds of coal were built using the least-squares method.The spectrum of the unknown sample was analyzed based on these twenty libraries to estimate its element contents.With the initial estimated result,the procedure of developing library and analysis was iterated to build a new library with the closest element contents to the unknown sample.Hence the experiment-LLs method can reduce non-linear radiation effects.The experiment-LLs method was performed on an improved coal analysis system which was equipped with a long-life 14 MeV pulsed-neutron generator,a bulk BGO detector with a temperature controller,a moisture meter and coal-smoothing device.The precisions of this system for ash content,water content,volatile content and calorific value have reached 1.0wt%,0.5wt%,1.0wt%,350 kJ/kg,respectively. | WANG HuiDong LU JingBin LU YuPing YANG Dong MA KeYan YANG Kang LIU YuMin CHENG DaoWen | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，11： | 6 |
| 15 | HMW glutenin subunits in multiploid Aegilops species: composition analysis and molecular cloning of coding sequences显示文摘The Aegilops genus contains species closely related to wheat. In common with wheat, Aegilops species accumulate high molecular weight (HMW) glutenin subunits in their endospermic tissue. In this study, we investigated the composition of HMW glutenin subunits in four multiploid Aegilops species using SDS-PAGE analysis. Furthermore, by working with Ae. ventricosa, we established an efficient ge-nomic PCR condition for simultaneous amplification of DNA sequences coding for either x- or y-type HMW glutenin sub-units from polyploid Aegilops species. Using the genomic PCR condition, we amplified and subsequently cloned two DNA fragments that may code for HMW glutenin subunits in Ae. ventricosa. Based on an analysis of the deduced amino acid sequences, we concluded that the two cloned sequences encode one x- and one y-type of HMW glutenin subunit, respectively. | Ruili Xie Yongfang Wan Yan Zhang Daowen Wang | 2001 | Chinese Science Bulletin2001，46，4： | 6 |
| 16 | Aerosol observation in Fengtai area,Beijing显示文摘Measurements of aerosol number concentration and particulate matter with diameter less than 10 m(PM10) mass concentrations of urban background aerosols were performed in Fengtai area,Beijing in 2006.Black carbon(BC) was collected simultaneously from the ground and analyzed to determine the particulate matter components.To satisfy the interest in continuous monitoring of temporal and spatial distribution of aerosols,the relationship between extinction coefficient(visibility) measured by lidar remote sensing and the aerosol number concentration measured from the ground was derived by using statistical method.Vertical particle number concentration profile within the planetary boundary layer could be inversed through the lidar data as well as the statistical relation. | Zengdong Liu Jianguo Liu Bei Wang Fan Lu Shuhua Huang Dexia Wu Daowen Hart | 2008 | Particuology2008，6，3： | 6 |
| 17 | Assessment of the individual and combined effects of Rht8 and Ppd-D1a on plant height, time to heading and yield traits in common wheat显示文摘Grain yield in cereal crops is a complex trait controlled by multiple genes and influenced by developmental processes and environment. Here we report the effects of alleles Rht8 and Ppd-D1 a on plant height, time to heading, and grain yield and its component traits. Association analysis and quantitative trait locus mapping using phenotypic data from 15 environments led to the following conclusions. First, both Rht8 and Ppd-D1 a reduce plant height. However, Ppd-D1 a but not Rht8 causes earlier heading.Second, both Rht8 and Ppd-D1 a promote grain yield and affect component traits. Their combined effects are substantially larger than those conferred by either allele alone.Third, promotion of grain yield by Rht8 and Ppd-D1 a is through increasing fertile spikelet number. We speculate that Rht8 and Ppd-D1 a act independently and additively in control of plant height, grain yield and yield component. Combination of the two alleles is desirable for adjusting plant height and enhancing grain yield and abiotic stress tolerance. | Kunpu Zhang Junjun Wang Huanju Qin Zhiying Wei Libo Hang Pengwei Zhang Matthew Reynolds Daowen Wang | 2019 | The Crop Journal2019，7，6： | 5 |
| 18 | Pandemonium Breaks Out:Disruption of Salicylic Acid-Mediated Defense by Plant Pathogens显示文摘Salicylic acid (SA) or 2-hydroxybenoic acid is a phenolic plant hormone that plays an essential role in plant defense against biotrophic and semi-biotrophic pathogens. In Arabidopsis, SA is synthesized from chorismate in the chloroplast through the ICS1 (isochorismate synthase I) pathway during pathogen infectioru The transcription co-activator NPR1 (Non-Expresser of Pathogenesis-Related Gene 1), as the master regulator of SA signaling, interacts with transcription factors to induce the expression of anti-microbial PR (Pathogenesis-Related) genes. To establish successful in fections, plant bacterial, oomycete, fun gal, and viral pathogens have evolved at least three major strategies to disrupt SA-mediated defense? The first strategy is to reduce SA accumulation directly by converting SA into its inactive derivatives. The second strategy is to interrupt SA biosynthesis by targeting the ICS1 pathway. In the third major strategy, plant pathogens deploy different mechanisms to interfere with SA downstream signaling. The wide array of strategies deployed by plant pathogens highlights the crucial role of disruption of SA-mediated plant defense in plant pathogenesis. A deeper understanding of this topic will greatly expand our knowledge of how plant pathogens cause diseases and consequently pave the way for the development of more effective ways to corn trol these diseases. | Guang Qi Jian Chen Ming Chang Huan Chen Katherine Hall John Korin Fengquan Liu Daowen Wang Zheng Qing Fu | 2018 | Molecular Plant2018，11，12： | 5 |
| 19 | Nuclear miR-665 aggravates heart failure via suppressing phosphatase and tensin homolog transcription显示文摘Although numerous miRNAs have been discovered,their functions in the different subcellular organelles have remained obscure.In this study,we found that miR-665 was enriched in the nucleus of cardiomyocytes,and then investigated the underlying role of nuclear miR-665 in heart failure.RNA fluorescence in situ hybridization assays in human heart tissue sections and primary cardiomyocytes showed that miR-665 was localized in the nucleus of cardiomyocytes.Increased expression of nuclear miR-665 was observed not only in the cardiomyocytes isolated from the heart of mice treated in vivo by transverse aortic constriction(TAC),but also in phenylephrine(PE)-treated cultured cardiomyocytes in vitro.To further explore the role of miR-665 in heart failure,a type 9 recombinant adeno-associated virus(rAAV)system was employed to manipulate the expression of miR-665 in mice.Overexpression of miR-665 aggravated TAC-induced cardiac dysfunction,while down-expression of miR-665 showed opposite effects.Bioinformatic prediction and biological validation confirmed that the PTEN(phosphatase and tensin homolog)gene was one of the targets of miR-665 in the nucleus.Furthermore,restoring PTEN expression significantly eliminated the destructive effects of miR-665 over-expression in TAC-induced cardiac dysfunction.Our data showed that nuclear miR-665 aggravates heart failure via inhibiting PTEN expression,which provided a therapeutic approach for heart failure. | Jiahui Fan Xudong Zhang Xiang Nie Huaping Li Shuai Yuan Beibei Dai Jiabing Zhan Zheng Wen Jiangang Jiang Chen Chen Daowen Wang | 2020 | Science China(Life Sciences)2020，63，5： | 4 |
| 20 | Molecular genetic and genomic analysis of wheat milling and end-use traits in China:Progress and perspectives显示文摘Wheat is the most widely cultivated staple food crop, and multiple types of food derivatives are processed and consumed globally. Wheat grain quality(WGQ) is central to food processing and nutritional value, and is a decisive factor for consumer acceptance and commercial value of wheat cultivars. Hence, improvement in WGQ traits is top priority for both conventional and molecular wheat breeding. In this review we will focus on two important WGQ traits, grain milling and end-use, and will summarize recent progress in China. Chinese scientists have invested substantial effort in molecular genetic and genomic analysis of these traits and their effects on end-use properties. The insights and resources generated have contributed to the understanding and improvement of these traits. As high-quality genomics information and powerful genome engineering tools are becoming available for wheat, more fundamental breakthroughs in dissecting the molecular and genomic basis of WGQ are expected. China will strive to make further significant contributions to the study and improvement of WGQ in the genomics era. | Daowen Wang Kunpu Zhang Lingli Dong Zhenying Dong Yiwen Li Abrar Hussain Huijie Zhai | 2018 | The Crop Journal2018，6，1： | 4 |
您所在的机构暂未开通此部分的功能，请联系管理员