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| 1 | Effects of Traditional Chinese Medicine Shensong Yangxin Capsules on Heart Rhythm and Function in Congestive Heart Failure Patients with Frequent Ventricular Premature Complexes:A Randomized, Double-blind, Multicenter Clinical Trial显示文摘 | Xi Wang Dan HU Song Dang He Huang Cong-Xin Huang Ming-Jie Yuan Yan-Hong Tang Qing-Shan Zheng Fang Yin Shu Zhang Bo-Li Zhang Run-Lin Gao | 2017 | Chinese Medical Journal2017，，14： | 33 |
| 2 | A preliminary study of the effects of plastic film-mulched raised beds on soil temperature and crop performance of early-sown short-season spring maize(Zea mays L.) in the North China Plain显示文摘To identify a strategy for earlier sowing and harvesting of spring maize(Zea mays L.) in an alternative maize–maize double cropping system, a 2-year field experiment was performed at Quzhou experimental station of China Agricultural University in 2014 and 2015. A short-season cultivar, Demeiya number 1(KX7349), was used in the experiment. Soil temperature to 5 cm depth in the early crop growth stage, crop growth, crop yield, and water use of different treatments(plastic film-mulched raised bed(RF) and flat field without plastic film mulching(CK) in 2014; RF, plastic film-mulched flat field(FF), and CK in 2015)were measured or calculated and compared. Soil temperature in the film-mulched treatments was consistently higher than that in CK(1.6–3.5 °C in average) during the early growth stage. Crops in plastic film-mulched treatments used 214 fewer growing-degree days(GDDs) in 2014 and 262 fewer GDDs in 2015. In 2014, the RF treatment yielded 32.7%higher biomass than CK, although its 9.4% higher grain yield was not statistically significant. Also, RF used 17.9% less water and showed 33.1% higher water use efficiency(WUE) than CK. In 2015, RF and FF showed 56.2% and 49.5% higher yield, 15.0% and 4.5%lower water use(ET), and 63.4% and 75.7% higher WUE, respectively, than CK. RF markedly increased soil temperature in the early crop season, accelerated crop growth, reduced ET,and greatly increased crop yield and WUE. Compared with FF, RF had no obvious effect on crop growth rate, although soil temperature during the period between sowing and stem elongation was slightly increased. However, RF resulted in lower ET and higher WUE than FF. Effects of RF on soil water dynamics as well as its cost-effectiveness remain topics for further study. | Jing Dang Weili Liang Guiyan Wang Pengfei Shi Dan Wu | 2016 | The Crop Journal2016，4，4： | 10 |
| 3 | TIM-1 acts a dual-attachment receptor for Ebolavirus by interacting directly with viral GP and the PS on the viral envelope显示文摘Ebolavirus 能与 50%90% 的死亡率在人引起出血性的发烧。当前,没有同意的疫苗和抗病毒的治疗是可得到的。人的 TIM1 为 EBOV 被看作一个附件因素,提高通过和位于病毒的信封的 PS 的相互作用的病毒的感染。然而,推理由 filovirus 位于 hTIM-1,然而并非另外的 PS 有约束力的受体的更好的用法下面,未知的遗体。我们第一在 vitro 表明了在 hTIM-1 和 EBOV GP 之间的一个直接相互作用并且决定了 hTIM-1 和 hTIM-4 的 Ig V 领域的水晶结构。在到 EBOV GP 的 hTIM-1 的有约束力的区域被怪物和变化试金印射,它基于结构的分析被设计。象点异种一样用 hTIM-1 和它的相当或相同的事物执行的 Pseudovirion 感染试金在 EBOV 细胞的入口验证了 GP 有约束力的地点和 EBOV GP-hTIM-1 相互作用的重要性的地点。 | Shuai Yuan Lei Cao Hui Ling Minghao Dang Yao Sun Xuyuan Zhang Yutao Chen Liguo Zhang Dan Su Xiangxi Wang Zihe Rao | 2015 | Protein & Cell2015，6，11： | 6 |
| 4 | Isotherm Equation Study of F Adsorbed from Water Solution by Fe2(SO4)3-modified Granular Activated Alumina显示文摘The adsorption equilibrium of a fluoride solution on 1-2 mm granular activated alumina modified by Fe2(SO4)3 solution was investigated.The experiments were conducted using a wide range of initial fluoride concentrations(0.5 to 180 mg·L-1 at pH~7.0) and an adsorbent dose of 1.0 g·L-1.The application of Langmuir and Freundlich adsorption isotherm models(linear and nonlinear forms) generally showed that a single Langmuir or Freundlich equation cannot fit the entire concentration gap.Experimental data on low equilibrium concentrations(0.1 to 5.0 mg·L-1) was in line with both Langmuir and Freundlich isotherm models,whereas that of high equilibrium concentrations(5.0 to 150 mg·L-1) was more in line with the Freundlich isotherm model.A new LangmuirFreundlich function was used for the entire concentration gap,as well as for low and high concentrations. | DANG Dan DING Wenming CHENG Anguo LIU Shuming ZHANG Xu | 2011 | Chinese Journal of Chemical Engineering2011，19，4： | 5 |
| 5 | Effect of Berberine on Activation of TLR4-NFκB Signaling Pathway and NLRP3 Inflammasome in Patients with Gout显示文摘Objective:To determine the effects of berberine(BBR) on the activation of toll-like receptor 4(TLR4),nuclear factor(NF) κB(NF-κB) signaling and NLRP3 inflammasome in patients with gout.Methods:Peripheral blood mononuclear cells(PBMCs) were obtained from 24 acute(AP) and 41 non-acute(NAP) phases of primary gout patients,respectively,as well as 30 healthy controls(HC).TLR4,NF-κB(p65),NLRP3,apoptosis-associated specklike protein containing a CARD(PYCARD),cysteinyl aspartate specific proteinase-1(CASP1),and interleukin-1 β(IL-1 β) mRNA expression levels in PBMCs were measured by quantitative reverse transcriptase polymerase chain reaction.The protein levels of TLR4,myeloid differentiation factor 88(MyD88),NF-κB(p50/65),inhibitor of kappa B kinase α/β(IKKα/β),NF-κB inhibitor α(IKB α),phospho-IKKα/β(p-IKKα/β),NLRP3,PYCARD,and CASP1were monitored by Western blotting.Serum IL-1 β protein level was measured using enzyme-linked immunosorbent assay(ELISA).In addition,PBMCs from HC and macrophages derived from a spontaneously immortalized monocyte-like cell line(THP-1) were stimulated using monosodium urate(MSU,100 μ g/mL),0.1% dimethyl sulfoxide,25 μmol/L BBR,and 10,25,and 50 μmol/L BBR+100 μg/mL MSU for different time periods.The protein levels of IL-1β and IL-18 in cell culture supernatants was measured by ELISA,and the protein expressions of TLR4,MyD88,NF-κB(p50/p65),IKK α/β,IκBα,p-IKKα/β,NLRP3, PYCARD,and CASP1 in macrophages were analyzed by Western blotting.Results:(1) TLR4,NF-κB(p65),PYCARD,CASP1,and IL-1β mRNA levels in PBMCs were significantly higher in the AP group than in the HC group(P<0.05).The NLRP3 mRNA expression levels in PBMCs were found to be significantly lower in the AP and NAP groups than in the HC group(P<0.05,P<0.01).(2) The protein levels of TLR4,IKKβ,MyD88,NF-κB,p-IKKα/β,PYCARD,and CASP1 in PBMCs were significantly higher,and those of IκBα,IKKα,and NLRP3 were found to be significantly lower in the AP group than in the HC group(P<0.05 or P<0.01).(3) The serum IL-1β protein levels were significantly higher in the AP and NAP groups than in the HC group(P<0.01).(4)The IL-1β protein level was significantly lower in the culture supernatants of the PBMCs stimulated with MSU for 3 and 6 h in the 25 and 50 μmoL/L BBR groups compared with that in the MSU group(P<0.01).(5) The protein levels of IL-1β and IL-18 were also significantly lower in the culture supernatants of macrophages stimulated with MSU for 3 and 6 h in BBR groups compared with those in the MSU group(P<0.01).(6) The protein levels of TLR4, MyD88,NF-κB(p50,p65,p105),IKKα/β,p-IκBα,p-IKKα/β,PYCARD,and CASP1 were significantly differed between the macrophages stimulated with MSU for 0.5 and 6 h in BBR groups compared with those in the MSU group(P<0.05 or P<0.01).Conclusions:Activation of TLR4-NF κB signaling and NLRP3 inflammasome by MSU crystals drives the progression of gout inflammation.BBR ameliorates gouty inflammation,which is mechanistically associated with its regulation of TLR4-NF-κB signaling and NLRP3inflammasome expression. | DANG Wan-tai XU Dan ZHOU Jing-guo | 2023 | Chinese Journal of Integrative Medicine2023，29，1： | 3 |
| 6 | Integrated Building Envelope Design Process Combining Parametric Modelling and Multi-Objective Optimization显示文摘As an important element in sustainable building design, the building envelope has been witnessing a constant shift in the design approach. Integrating multi-objective optimization(MOO) into the building envelope design process is very promising, but not easy to realize in an actual project due to several factors, including the complexity of optimization model construction, lack of a dynamic-visualization capacity in the simulation tools and consideration of how to match the optimization with the actual design process. To overcome these difficulties, this study constructed an integrated building envelope design process(IBEDP) based on parametric modelling, which was implemented using Grasshopper platform and interfaces to control the simulation software and optimization algorithm. A railway station was selected as a case study for applying the proposed IBEDP, which also utilized a grid-based variable design approach to achieve flexible optimum fenestrations. To facilitate the stepwise design process, a novel strategy was proposed with a two-step optimization, which optimized various categories of variables separately. Compared with a one-step optimization,though the proposed strategy performed poorly in the diversity of solutions, the quantitative assessment of the qualities of Pareto-optimum solution sets illustrates that it is superior. | Dan Hou Gang Liu Qi Zhang Lixiong Wang Rui Dang | 2017 | Transactions of Tianjin University2017，23，2： | 3 |
| 7 | Effect of Reduction and Carburization Pretreatment on Iron Catalyst for Synthesis of Light Olefins from CO Hydrogenation显示文摘 | AN Tong DANG Dan CHENG Yi | 2017 | Chemical Research in Chinese Universities2017，33，4： | 2 |
| 8 | Supersensitive linear pi- ezoresistive property in carbon nanotubes/silicone rubber nanocom- posites 显示文摘 | Dang Zhimin Jiang Meijuan Xie Dan | 2008 | Applied Physics2008，104，02： | 1 |
| 9 | C,Dielectric behavior and dependence of percolation threshold on the conductivity of fillers in polymer-semiconductor composites显示文摘 | Dang Zhimin Nan Cewen Xie Dan Zhang Yihe Tjong S | 2004 | Applied Physics Letters2004，85，： | 1 |
| 10 | Study on dielectric behavior of the ferroelectric poly (vinylidene fluoride)/Li and Ti codoped NiO composites显示文摘 | DANG ZHI-MIN XU HAI-PING XIE DAN | 2007 | Materials Letters2007，61，2： | 1 |
| 11 | Design and implementation of web user interface automatic generation tool显示文摘 | HOU Yan'e DANG Lanxue WEl Dan | 2011 | Journal of Henan University(Natural Science)2011，41，6： | 1 |
| 12 | Real Time Relative and Absolute Dynamic Localization of Air–Ground Wireless Sensor Networks显示文摘 | Pritpal Dang Prasanna Ballal Frank L. Lewis Dan O. Popa | 2008 | Journal of Intelligent and Robotic Systems2008，，2： | 1 |
| 13 | Current overview of myasthenia gravis and experience in China显示文摘Myasthenia gravis(MG)is an acquired autoimmune disease affecting synaptic transmission via the neuromuscular junction mainly due to the presence of auto-antibodies targeting acetylcholine receptors.Ocular or generalized MG is clinically diagnosed when the extra-ocular muscles or other muscle groups beyond the extra-ocular muscles are involved.MG occurs in both sexes at any ages from all races but shows a wide variability in incidence and prevalence.Differences in clinical phenotypes of MG patients between West and East countries have been observed.Herein,we review the current concept on epidemiology,classification,and generalized progression in MG,mainly focusing on the differential features from China's Mainland. | Jun Guo Dan Dang Hong-Zeng Li Zhu-Yi Li | 2014 | Neuroimmunology and Neuroinflammation2014，1，1： | 1 |
| 14 | Overexpression of CaWRKY27 , a subgroup IIe WRKY transcription factor of Capsicum annuum , positively regulates tobacco resistance to Ralstonia solanacearum infection显示文摘 | Fengfeng Dang Yuna Wang Jianju She Yufen Lei Zhiqin Liu Thomas Eulgem Yan Lai Jing Lin Lu Yu Dan Lei Deyi Guan Xia Li Qian Yuan Shuilin He | 2014 | Physiol Plantarum2014，，3： | 1 |
| 15 | Three- dimensional imaging via wideband MIMO radar system 显示文摘 | Qing Ge Dang Dan Wang Wei | 2010 | IEEE Geoseiences and Remote Sensing Letters2010，7，3： | 1 |
| 16 | A novel electrochemical method for determination of cis-jasmone based on enhancement effect of cetyltrimethy-lammonium bromide显示文摘 | Xueping Dang Chengguo Hu Dan Shen | | 0，，： | 1 |
| 17 | Dielectric behavior and dependence of percolation threshold on the conductivity of fillers in polymer-semiconductor composites显示文摘 | Dang Zhiming Nan Cewen Xie Dan | 2004 | Applied Physics Letters2004，85，1： | 1 |
| 18 | Nanoscale imaging and mechanical analysis of viral infection on cells by atomic force microscopy显示文摘Investigating the mechanical cues involved in virus-cell interactions opens novel possibilities for understanding the underlying mechanisms guiding viral infection,which will have great impacts on virology and human health.The threat from viruses to human health is increasingly severe,and new deadly viruses are constantly discovered in the world,including severe acute respiratory syndromerelated coronavirus,severe acute respiratory syndrome coronavirus 2,Middle East respiratory syndrome-related coronavirus(MERSCoV),Zika virus(ZIKV),Ebola virus,avian influenza virus,and so on[1-3],which pose unprecedented burden to human society.Hence,investigating the detailed processes of viral infections and pathological changes is of considerable practical significance for developing antiviral therapeutics. | Bin Liu Dan Dang Yang Yang Peng Yu Mi Li | 2020 | Acta Biochimica et Biophysica Sinica2020，52，11： | 1 |
| 19 | Dielectric behavior and dependence of percolation threshold on the conductivity of fillers in polymer-semiconductor composites 显示文摘 | Dang Z M Nan C W Dan X | 2004 | Applied Physics Letters2004，85，1： | 1 |
| 20 | Numerical Simulation of a Coke Oven显示文摘 | Hao Dan Dan Liu Wen Sheng Dang Le Ping Wei Hong Yuan | 2012 | Advanced Materials Research . 2012 (479)2012，，479： | 1 |
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