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1澳大利亚临床共识指南:儿童卒中的诊断和急性期处理显示文摘卒中是导致儿童死亡的十大原因之一,幸存的致残患儿将面临几十年的残疾生活,给患儿及其家庭带来了巨大负担。由于安全性和有效性的证据有限,以及诊断的延误,目前卒中患儿无法接受再灌注治疗。儿童卒中诊断和急性期处理的澳大利亚临床共识指南,旨在最大限度地减少临床诊疗中的不确定性,并记录与成人卒中不同的危险因素、病因和假性卒中情况的最佳证据。临床问题的阐述来自于对2007年至2017年数据库的系统检索,但仅限于英语和儿科研究。该指南应用SIGN方法和国家健康与医学研究委员会系统对证据进行筛选和分类,通过推荐、评估、发展和评价系统(GRADE系统)对推荐进行强弱分级。该指南提供了60多项基于证据的推荐,以帮助参与院前和急症处理的临床医师快速识别儿童卒中,选择最合适的初步检查方案来确定诊断、明确病因,并选择最恰当的干预措施以挽救脑组织、预防复发。同时,指南也提供了颅内压和先天性心脏病管理方面的推荐。该指南的实施需要将院前和急诊系统重组,包括建立区域性卒中网络,建立儿科卒中疾病编码,快速MRI,以及对能够提供再灌注治疗的初级儿科卒中中心进行认证。该指南能够审核治疗的基准时间线,获得急性期的干预措施及预后判断。它还将促进澳大利亚儿童卒中登记的发展,并与国际登记处建立数据联系,以便准确收集卒中发病率、治疗和结果相关的数据。Medley TL Miteff C Andrews I Ware T Cheung M Monagle P Mandelstam S Wray A Pridmore C Troedson C Dale RC Fahey M Sinclair A Walsh P Stojanovski S Macka MT 徐佳丽(译) 吴川杰(译) 肖潇(译) 吕俊萱(译) 张博维(译) 吉训明(译) 2019中国脑血管病杂志2019,16,4:9
2Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation.Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme 2013Journal of Animal Science and Biotechnology2013,4,4:3
3Acute surgical emergencies in inflammatory bowel disease显示文摘Dale F Berg Anil M Bahadursingh Donald L Kaminski Walter E Longo 2002The American Journal of Surgery2002,,:2
4Processing of low-density silica gel by critical point drying or ambient pressure drying显示文摘Valerie D Land Thomas M Harris Dale C Teeters 2001Journal of Non-Crystalline Solids2001,,1:2
5Evolution of endovascular mechanical thrombectomy for acute ischemic stroke显示文摘Acute ischemic stroke(AIS) is a common medical problem associated with significant morbidity and mortality worldwide. A small proportion of AIS patients meet eligibility criteria for intravenous thrombolysis(IVT) with recombinant tissue plasminogen activator, and its efficacy for large vessel occlusion is poor. Therefore, an increasing number of patients with AIS are being treated with endovascular mechanical thrombectomy when IVT is ineffective or contraindicated. Rapid advancement in catheter-based and endovascular device technology has led to significant improvements in rates of cerebral reperfusion with these devices. Stentrievers and modern aspiration catheters have now surpassed earlier generation devices in the degree and rapidity of revascularization. This progress has been achieved with no concurrent increase in risk of major complications or mortality, both when used alone or in combination with IVT. The initial randomized controlled trials comparing endovascular therapy to IVT for AIS failed to show superior outcomes with endovascular treatment, butkey limitations of each trial may limit the significance of these results to current practice. While endovascular devices and operator experience continue to evolve, we are optimistic that this will be accompanied by improvements in patient outcomes. This review highlights the major endovascular devices used in current practice and the trials which have investigated their efficacy.Colin J Przybylowski Dale Ding Robert M Starke Christopher R Durst R Webster Crowley Kenneth C Liu 2014World Journal of Clinical Cases2014,2,11:2
6Radiative Propertiesof Burning Alumin um Droplets 显示文摘Brewster M Q Dale MT 1988Combustion and Flame1988,72,:2
7Dynamic habitat selection by two wading bird species with divergent foraging strategies in a seasonally fluctuating wetland显示文摘Beerens James M Gawlik Dale E Herring Garth Cook Mark I 2011EN2011,,4:2
8In vivo tracing of major rat brain pathways using manganese-enhanced magnetic resonance imaging and three-dimensional digital atlasing显示文摘Leergaard T B Bjaalie J O Devor A Wald L L Dale A M 2003Neuroimage2003,20,:1
9Stabilizability and existence of system representations for discrete-time time-varying systems显示文摘DALE M S 1993SIAM Journal of Control and Optimi- zation1993,,:1
10Reversible in- hibitor of β-glucosidase 显示文摘DALE M P ENSLEY H E KERN K 1985Biochemistry1985,24,:1
11High-level expression of the rat whey acidic protein gene is mediated by elements in the promoter and 3' untranslated region显示文摘Dale T C Krnacik M J Schmidhouser C 1992Mol Cell Biol1992,12,3:1
12True metabolizable ener- gy of fats at low level dietary inclusion 显示文摘DALE N M FALLER H L 1982Poultry Science1982,61,12:1
13Ethanolic fermentation of hydroly- sates from ammonia fiber expansion ( AFEX) treated com stover and distillers grain without detoxification and external nutrient supplementation显示文摘Lau M W Dale B E Balan V 2008Biotechnology and bioengineering2008,99,3:1
14Cortical Surface -based analysis Ⅰ: segmentation and surface reconstruction 显示文摘A Dale B Fischl M Sereno Neuroimage0,9,:1
15Application of high energy ignition systems to engines 显示文摘DALE J D CHECKCL M D SMY P R 1997Progress in Energy and Combustion Science1997,23,5:1
16The genome organization of banana bunchy top virus analysis of six ss-DNA components 显示文摘Burns T M Harding R M Dale J L 1995J Gen Virol1995,76,:1
17Chronic ulcer of the leg: clinical history 显示文摘Callam M J Harper DR Dale JJ 1987Br Med J (Clin Res Ed)1987,294,:1
18Sleep deprivation in critical illness :its role in physical and psychological recovery 显示文摘Dale M Needham J 2012IntCare Med2012,7,2:1
19Bronchodilator activity of bitter tastants in human tissue 显示文摘Belvisi M G Dale N Birrell M A 2011Nat Med2011,17,7:1
20Oral cancer risk in relation to sexual history and evidence of human papillomavirus infection显示文摘Schwartz S M Daling J R Doody D R 0,,21:1
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