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531篇 您的检索式:作者名="DUTT"
    题名 作者 年代 出处 被引量
1A study on p53 gene alterations in esophageal squamous cell carcinoma and their correlation to common dietary risk factors among population of the Kashmir valley显示文摘瞄准:为了系统地检验风险因素的关联的程度,例如年龄,与原因的体的 Tp53 分子损害消费了饮食的习惯和家庭倾向在北印度的 Kashmiri 人口之中提高食道的有鳞的房间癌(ESCC ) 的致癌作用严厉。方法:所有情况(n = 51 ) 并且控制(n = 150 ) 是克什米尔山谷的永久居民。基因改变在 Tp53 肿瘤的前 ons 5-8 被决定压制或在 45 个 ESCC 盒子之中的基因组织学地由 PCR-SSCP 分析证实了。为单个癌症盒子的数据(n = 45 ) 并且住院病人控制(n = 150 ) 与非癌症,疾病在癌症的家庭历史上包括了信息,与病人的年龄组一起的三十个占优势的普通饮食的风险因素。在到从这些参数的万物有灵论的数据的 p53 前 ons 的基因损害的关联被 Chi 平方测试与健康控制一起产生到所有 45 个组织学地证实的 ESCC 盒子。结果:(77.8%) 45 中的 35 个组织学地描绘了与 45 正常样品中的 1 个对比的有的类似的体细胞突变从一样的耐心的显示出的细菌线变化从邻近的区域获得了的肿瘤样品。 SSCP 分析表明了改变在 6 上在前被发现的那很普通的 p53 基因(77.7%),那没与个人和 clinicopathological 参数的年龄相关,但是与癌症的家庭历史显示出重要词语索引( P<0.05 )( CD = 58 ),在消费的一个未知地点,和饮食的习惯建议细菌线倾向局部地种芥属蔬菜“ Hakh ”( CD = 19.5 ),红 chillies ( CD = 20.2 ),热咸苏打茶( CD = 2.37 )并且本地烤的面包( CD = 1.1 )。结论:我们的学习建议那体的染色体变化特别在 6 Tp53 基因上的前,在人种上的食道的癌症病人之中,克什米尔山谷的同质的人口是仔细与到各种各样的普通饮食的风险因素,特别热的咸茶,肉,烤的面包和“ Hakh ”的继续的暴露有关,那富于 nitrosoamines 和家庭癌症历史。Imtiyaz Murtaza Dhuha Mushtaq Mushtaq A Margoob Amit Dutt Nisar Ahmad Wani Ishfaq Ahmad Mohan Lal Bhat 2006World Journal of Gastroenterology2006,12,25:8
2Higher-order topological insulators in synthetic dimensions显示文摘Conventional topological insulators support boundary states with dimension one lower than that of the bulk system that hosts them,and these states are topologically protected due to quantized bulk dipole moments.Recently,higherorder topological insulators have been proposed as a way of realizing topological states with dimensions two or more lower than that of the bulk due to the quantization of bulk quadrupole or octupole moments.However,all these proposals as well as experimental realizations have been restricted to real-space dimensions.Here,we construct photonic higher-order topological insulators(PHOTIs)in synthetic dimensions.We show the emergence of a quadrupole PHOTI supporting topologically protected corner modes in an array of modulated photonic molecules with a synthetic frequency dimension,where each photonic molecule comprises two coupled rings.By changing the phase difference of the modulation between adjacent coupled photonic molecules,we predict a dynamical topological phase transition in the PHOTI.Furthermore,we show that the concept of synthetic dimensions can be exploited to realize even higher-order multipole moments such as a fourth-order hexadecapole(16-pole)insulator supporting 0D corner modes in a 4D hypercubic synthetic lattice that cannot be realized in real-space lattices.Avik Dutt Momchil Minkov Ian A.D.Williamson Shanhui Fan 2020Light(Science & Applications)2020,9,1:3
3Shifting dynamics of nature, society and agriculture in the Hindu Kush Himalayas: Perspectives for future mountain development显示文摘Current approaches for sustainable mountain development have several persisting warning signals. Economic globalization, profitoriented market development, and infrastructure development have significantly altered traditional nature-society interactions, increased environmental pressures, and challenged agricultural sustainability in the mountains. Some of the effects of globalization could also be beneficial. Social differentiation and disintegration of mountain communities' have weakened their collective stakes on natural resources resulting in decline in initiatives such as community forestry, collective water management, domestication of rapidly disappearing herbal species, and balancing of economic and ecological concerns. Population growth, food insecurity, unemployment, and increasing economic gaps between rich and poor have led to out-migration of youth. Sustained action promoting ownership of new initiatives for rehabilitating degraded mountain landscapes through macro-level global/national initiatives, mountain specific planning and development efforts is severely lacking in many areas on the Hindu Kush Himalayan region. Therefore, there is an urgent need for widening the scope of efforts directed to help mountain areas and communities, and a future thinking approach to enhance the sustainability of mountain areas as they are a valuable natural resource for humankind. This paper discusses the issues, opportunities, and provides suggestions for the future of mountain development.BHATTA Laxmi Dutt SHRESTHA Anil NEUPANE Nilhari JODHA Narpat Singh WU Ning 2019Journal of Mountain Science2019,16,5:2
4Protective effect of Sida cordata leaf extract against CCl_4 induced acute liver toxicity in rats显示文摘Objective:To investigate the hepatoprotective potential of Sida cordata(Malvaceae)(S.cordata) in experimental rats to validate its traditional claim.Methods:Wister albino rats were divided into 6 groups:Croup 1 served as control;CroupⅡserved as hepatotoxic(CCl4 treated) group; CroupⅢ,Ⅳand V served as(100,200 and 400 mg/kg b.w.) S.cordata leaf extract(SCLE) treated groups;CroupⅥserved as positive control(Silymarin) treated group.Liver marker enzymes serum glutamate oxyloacetic transaminase,serum glutamic pyruvic transaminase,pancreatic enzymatic antioxidants superoxide dismutase(SOD),lipid peroxidation,catalase(CAT),reduced glutathione(CSH) were measured and compared along with histopathological studies.Results: Obtained results show that the treatment with SCI.E significantly(P<0.05-<0.001) and dosedependently reduced CCl4 induced elevated serum level of hepatic enzymes.Furthermore, SCLE significantly(up to P<0.001) reduced the lipid peroxidation in the liver tissue and restored activities of defence antioxidant enzymes CSH,SOD and CAT towards normal levels,which was confirmed by the histopathological studies.Conclusions:The results of this study strongly indicate the protective effect of SCLE against CCl4 induced acute liver toxicity in rats and thereby scientifically support its traditional use.Sunil Mistry KR Dutt J Jena 2013Asian Pacific Journal of Tropical Medicine2013,6,4:2
5The basic and applied aspects of superoxide dismutase显示文摘Amit Bafana Som Dutt Arun Kumar Sanjay Kumar Paramvir S. Ahuja 2010B, Enzymatic2010,,2:2
6Saxena, characterization of 1,3-regiospecific lipases from new pseudomonas and bacillus isolates 显示文摘Gautam Kumar Meghwanshi Lata Agarwal Kakoli Dutt 2006Journal of Molecular Catalysis B: Enzymatic2006,40,:1
7Identification of a second begomovirus, Sri Lankan cassava mosaic virus, causing cassava mosaic disease in India显示文摘Dutt N Briddon R W Dasgupta I 2005Archives of Virology2005,150,10:1
8The a-chemokine, stromal cell-derived fac- tor-la, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduc- tion pathways显示文摘Ganju R K Brubaker S A Meyer J Dutt P Yang Y Qin S 1998J Biol Chem1998,273,23:1
9Therapeutic efficacy of poly (DL-lactid-Co-Glycolide)-encapsulated antitubercular drugs against Mycobacterium tuberculosis infection induced in mice显示文摘Dutt M Khuller GK 2001Antimicrob Agents Chemother2001,45,:1
10Chemotherapy of Mycobacterium tuberculo-sis infections in mice with a combination of isoniazid and rifampi-cin entrapped in Poly(DL-lactide-co-glycolide)microparticles显示文摘Dutt M KhulIer GK 2001J Antimicrob Chemother2001,47,6:1
11Growth of monosodium urate monohydrate crystals: effect of cartilage and synovial fluid components on in vitro growth rates显示文摘Burr HM Dutt YC 1986Ann Rheum Dis1986,45,:1
12Day to day use and service-related issues with the bone-anchored hearing aid: the Entific Medical Systems questionnaire显示文摘Dutt SN McDermott AL Jelbert A 2002Journal of Laryngology & Otology Supplement2002,28,:1
13The clinical and biological effects of thalidomide in patients with myelodysplastic syndromes显示文摘Zorat F Shetty V Dutt D 2001Br J Haematol2001,115,4:1
14Bionomics of the banana pseudostem weevil, Odoiporus longicollis显示文摘Dutt N Maiti B B 1973Journal of Entomology1973,34,1:1
15Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK显示文摘Ganju RK Dutt P Wu L 1998Blood1998,91,3:1
16Evaluation of parameters affectingAgrobacterium-mediated transformation of citrus显示文摘Dutt M Grosser J 2009Plant Cell Tissue and Organ Culture2009,98,3:1
17ultrasound echo envelope analysis using a homodyned K-distribution signal model 显示文摘Dutt V Greenleaf J F 1994Ultarasonic Imaging1994,16,4:1
18The aetiology of nasopharyngeal carcinoma 显示文摘McDermott AL Dutt SN Watkinson JC 2001Clin Otolarngol Allied Sci2001,26,2:1
19Thalidomide produces transfusion independence in long-standing refractory anemias of patients with myelodysplastic syndromes显示文摘Raza A Meyer P Dutt D 2001Blood2001,98,4:1
20Fast Fourier transforms for nonequispaced data,II 显示文摘Dutt A Rokhlin V 1995Applied and Computational Harmonic Analysis1995,2,1:1
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