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| 1 | Gastroenterologist perceptions of faecal microbiota transplantation显示文摘AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation(FMT).METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed.RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT,8% more than once. Ninety percent would refer patients with Clostridium difficile infection(CDI) for FMT if easily available,37% for ulcerative colitis,13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication,including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic,17% nasoduodenal,13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence,12% infection risk,10% non infectious adverse effects/lack of safety data,10% aesthetic,10% lack of efficacy,4% disease exacerbation,and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution.CONCLUSION: Despite general enthusiasm,most gastroenterologists have limited experience with,or access to,FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required. | Sudarshan Paramsothy Alissa J Walsh Thomas Borody Douglas Samuel Johan van den Bogaerde Rupert WL Leong Susan Connor Watson Ng Hazel M Mitchell Nadeem O Kaakoush Michael A Kamm | 2015 | World Journal of Gastroenterology2015，21，38： | 5 |
| 2 | Label-retaining liver cancer cells are relatively resistant to sorafenib显示文摘 | Hong-Wu Xin Chenwi M Ambe Danielle M Hari Gordon W Wiegand Tyler C Miller Jin-Qiu Chen Andrew J Anderson Satyajit Ray John E Mullinax Tomotake Koizumi Russell C Langan Douglas Burka Michelle A Herrmann Paul K Goldsmith Alexander Stojadinovic Udo Rudloff S | 2013 | Gut2013，，12： | 2 |
| 3 | Diabetes mellitus 显示文摘 | Douglas E Bennie M McAnaw J | 1998 | Pharm J1998，261，： | 1 |
| 4 | Coordinated supply chain management显示文摘 | Douglas J Thomas Paul M Grinffin | 1996 | European Journal of Operational Research1996，94，： | 1 |
| 5 | Phytase effects on amino acid digestibility in molted laying hens显示文摘 | Snow J L M W Douglas | 2003 | Poult Sci2003，82，： | 1 |
| 6 | Effects of landscape corridors on seed dispersal by birds显示文摘 | DOUGLAS J L BENJAMIN M B JOSHUA J T | 2006 | Science2006，309，7： | 1 |
| 7 | Nanoparticle networks reduce the flammability of polymer nanocomposites 显示文摘 | Kashiwagi T Du F M Douglas J F | 2005 | Nature Materials2005，4，12： | 1 |
| 8 | Toward an Integrative Theory of Counterproductive Workplace Behavior:A Causal Reasoning Perspective显示文摘 | MARTINKO M J GUNDLACH M J DOUGLAS S C | 2002 | International Journal of Selection and Assessment2002，10，12： | 1 |
| 9 | Marini, Efficient rectangular mixed finite elements in two and three space variables显示文摘 | F Breezi J Douglas Jr M Fortin | 1987 | RAIRO Model Math Anal Numer1987，4，： | 1 |
| 10 | Process synthesis for waste minimization显示文摘 | Douglas J M | 1992 | Ind Eng Chem Res1992，31，1： | 1 |
| 11 | RhoA and cytoskeletal disruption mediate reduced osteoblastogenesis and enhanced adipogenesis of human mesenchymal stem cells in modeled microgravity显示文摘 | Meyers V E Zayzafoon M Douglas J T McDonald J M | 2005 | J Bone Miner Res2005，20，10： | 1 |
| 12 | Air-water gas transfer in uniform channel flow显示文摘 | Douglas B M Gerhard H J | 1999 | Journal of hydraulic engineering1999，125，1： | 1 |
| 13 | New venture survival: Ignorance,external shocks, and risk reduction strategies显示文摘 | Shepherd D A Douglas E J Shanley M | 2000 | Journal of Business Venturing2000，，： | 1 |
| 14 | Nanoparticle Networks Reduce the Flammability of Polymer Nanocom- posites显示文摘 | Kashiwagi T Du F M Douglas F J et aI | 2005 | Nature Materials2005，12，4： | 1 |
| 15 | Anti-microbial action of melanocortin peptides and identification of a novel X-Pro-D/L-Val sequence in Gram-positive and Gram-negative bacteria显示文摘 | CHARNLEY M MOIR A J DOUGLAS C W | 2008 | Peptides2008，29，6： | 1 |
| 16 | The peroxisome proliferator-activated receptor-γ2 Pro12Ala variant:association with type 2 diabetes and trait differences 显示文摘 | Douglas J A Erdos M R Waranabe R M | 2001 | Diabetes2001，50，： | 1 |
| 17 | The approximation of the pressure by a mixed method in the simulation of miscible displacement显示文摘 | J Douglas Jr R E Ewing M F Wheeler | 1983 | RAIRO Numer Anal1983，17，： | 1 |
| 18 | Clinical value of polysomnography显示文摘 | Douglas N J Thomas S Jan M A | 1992 | Lancet1992，339，8789： | 1 |
| 19 | Five unit bolus oxytocin at cesarean delivery in women at risk of atnny: a randomized, double-blind, controlled trial显示文摘 | King K J douglas M J Unger W | 2010 | Anesth Analg2010，111，6： | 1 |
| 20 | Synthesis of high molecular weight polycarbonate by solid-state polymerization显示文摘 | Stephen M Gross George W Roberts Douglas J Kiserow | 2001 | Macromolecules2001，34，： | 1 |
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