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3114篇 您的检索式:作者名="DONNELLY"
    题名 作者 年代 出处 被引量
1润滑油抗氧剂协同作用研究显示文摘对润滑油的氧化机理做了简要阐述,并根据不同的抗氧作用机理,将抗氧剂分为三类:自由基清除剂(如酚类和胺类抗氧剂)、氢过氧化物分解剂(如氨基甲酸酯)和抗氧协合剂(如不含硫磷的钼酸酯)。利用加压差示扫描量热法(PDSC)对不同类型抗氧剂以及它们之间的协同作用进行了考察。研究表明,作为氢过氧化物分解剂,改进的无灰氨基甲酸酯具有比胺类、酚类抗氧剂更好的性能,这显示了氢过氧化物分解型抗氧剂巨大的应用潜力。研究还表明,具有相同抗氧机理的不同抗氧剂,如酚类和胺类抗氧剂,具有协同作用;不同作用机理的两抗氧剂之间,如自由基清除剂和氢过氧化物分解剂,具有更好的抗氧化协同效果,其中,无灰氨基甲酸酯与烷基化二苯胺抗氧剂具有最佳的抗氧协同效能,可成为高温无灰抗氧剂应用的一个很好选择;不同抗氧机理的三种抗氧剂复合,如烷基化二苯胺,氨基甲酸锌和有机钼酸酯组成的三元复合抗氧剂,具有更为优秀的抗氧化性能。通过不同机理抗氧剂之间的协同,不仅可以获得优秀的抗氧化性能,还可获得附加的极压、抗磨和减摩性能,而且有的减摩、抗磨性能还非常突出,如烷基化二苯胺、氨基甲酸锌和有机钼酸酯组成的三元复合添加剂体系。姚俊兵 Gaston Aguilar Steven G. Donnelly 2009润滑油2009,24,4:19
2Role of inflammation and infection in the pathogenesis of human acute liver failure: clinical implications for monitoring and therapy显示文摘Acute liver failure is a rare and devastating clinical condition. At present, emergency liver transplantation is the only life-saving therapy in advanced cases, yet the feasibility of transplantation is affected by the presence of systemic inflammation, infection and resultant multiorgan failure. The importance of immune dysregulation and acquisition of infection in the pathogenesis of acute liver failure and its associated complications is now recognised. In this review we discuss current thinking regarding the role of infection and inflammation in the pathogenesis of and outcome in human acute liver failure, the implications for the management of such patients and suggest directions for future research.Mhairi C Donnelly Peter C Hayes Kenneth J Simpson 2016World Journal of Gastroenterology2016,22,26:13
3PRECEDE-PROCEED模式在护理评估中的应用显示文摘PRECEDE-PROCEED模式在指导健康促进的临床、教育及科研工作中起着至关重要的作用。以“提高社区老龄糖尿病人群的生活质量”为例,从该模式的产生、模式评估步骤分析及模式的应用方面,详细分析了PRECEDE-PROCEED模式的结构及其在护理评估中的应用,为护理同行了解PRECEDE-PROCEED模式提供帮助。孟宪梅 Tam Truong Donnelly 2007护理研究(上旬版)2007,21,7:9
4Effects of elevation on spring phenological sensitivity to temperature in Tibetan Plateau grasslands显示文摘Vegetation phenology is an important indicator of climate change impacts on the seasonal dynamics of the biosphere. However, little is known about the influence of elevation on spring phenological sensitivity to temperature in an alpine ecosystem. Based on remotely sensed land surface phenology and temperature data from 2001 to2010, this study investigated the rate of spring phenological change of the Tibetan Plateau(TP) grasslands in response to interannual temperature variations at different elevations. Results suggest that spring phenology in the TP grasslands exhibits a stronger response to changes in temperature at higher elevations than at lower ones. In particular, spring phenology advanced by 1–2 days in response to a 1 °C increase in May average temperature at elevations from 3,000 to 3,500 m, while the rate was up to8–9 days/°C at 5,000–5,500 m. Analysis using accumulated growing degree days(AGDD) from January 1through May 31 showed the same general trend with increased elevation associated with increased sensitivity(as measured by phenological change per unit of AGDDchange). Such temperature sensitivity gradients in the TP grasslands could be partly explained by the growth efficiency hypothesis which suggests that vegetation adapted to colder climates likely requires less heat energy for the onset of growing season and vice versa in warmer climates.Furthermore, accumulated growing degree days from January 1 to the greenup date were found to decrease with increasing elevations, which provided evidence to support the applicability of the growth efficiency hypothesis in an alpine grassland ecosystem.Lingling Liu Liangyun Liu Liang Liang Alison Donnelly Isaac Park Mark D.Schwartz 2014Chinese Science Bulletin2014,59,34:7
5Psychosocial factors and their association with reflux oesophagitis,Barrett's oesophagus and oesophageal adenocarcinoma显示文摘AIM:To investigate the role of psychological characteristics as risk factors for oesophageal adenocarcinoma(OAC),as well as the reflux-mediated precursor pathway.METHODS:An all-Ireland population-based case-control study recruited 230 reflux oesophagitis(RO),224 Barrett's oesophagus(BO) and 227 OAC patients and 260 controls.Each case/control group completed measures of stress,depression,self-efficacy,self-esteem,repression and social support.A comparative analysis was undertaken using polytomous logistic regression adjusted for potential confounders.RESULTS:Compared to controls,OAC patients were almost half as likely to report high stress levels over their lifetime(P = 0.010,OR 0.51;95%CI:0.29-0.90)and 36% less likely to report having experienced depression(OR 0.64;95%CI:0.42-0.98).RO patients reported significantly higher stress than controls particularly during middle-and senior-years(P for trends < 0.001).RO patients were 37% less likely to report having been highly emotionally repressed(OR 0.63;95%CI:0.41-0.95).All case groups(OAC,RO and BO) were more likely than controls to report having had substantial amounts of social support(OR 2.84;95%CI:1.63-4.97;OR 1.97;95%CI:1.13-3.44 and OR 1.83;95%CI:1.03-3.24,respectively).CONCLUSION:The improved psychological profile of OAC patients may be explained by response shift.The role of psychological factors in the development of OAC requires further investigation.Paul Denver Michael Donnelly Liam J Murray Lesley A Anderson 2013World Journal of Gastroenterology2013,19,11:5
6Automated bolting and meshing on a continuous miner for roadway development显示文摘Automated installation of primary roof support material can potentially increase productivity and operator safety in the roadway development process within underground coal mining. Although the broader manufacturing sector has benefited from automation, several challenges exist within the Australian underground coal industry which makes it difficult to fully exploit these technologies. At the University of Wollongong a series of reprogrammable electromechanical manipulators have been designed to overcome these challenges and automatically handle the installation of roof and rib containment consumables on a continuous miner. The automated manipulation removes personnel from hazards in the immediate face area, particularly those associated with working in a confined and unstable working environment in close proximity to rotating and moving equipment. In a series of above ground trials the automated system was successfully demonstrated without human intervention and proven to be capable of achieving cycle times at a rate of 10 m per operating hour, consistent with that required to support high capacity longwall mines. The trials also identified a number of refinements which could further improve both cycle times and system reliability when considering the technology for underground use. The results have concluded that conventional manual handling practices on a continuous miner can be eliminated, and that the prototypes have significantly reduced the technical risk in proceeding to a full underground trial.van Duin Stephen Meers Luke Donnelly Peter Oxley Ian 2013International Journal of Mining Science and Technology2013,23,1:4
7Viral hepatitis in 2021:The challenges remaining and how we should tackle them显示文摘Viral hepatitis results in 1.4 million deaths annually.The World Health Organization(WHO)set an ambitious target to eliminate viral hepatitis by 2030,but significant challenges remain.These include inequalities in access to healthcare,reaching at risk populations and providing access to screening and effective treatment.Stigma around viral hepatitis persists and must be addressed.The WHO goal of global elimination by 2030 is a worthy aim,but remains ambitious and the coronavirus 2019 pandemic undoubtedly has set back progress.This review article will focus on hepatitis A to E,highlighting problems that have been resolved in the field over the past decade,those that remain to be resolved and suggest directions for future problem solving and research.Rebecca Dunn Aaron Wetten Stuart McPherson Mhairi C Donnelly 2022World Journal of Gastroenterology2022,28,1:4
8人口健康促进模式在社区护理中的应用显示文摘分析人口健康促进模式的组成,介绍其在加拿大社区护理中的应用,并以'老龄高血压病社区护理干预'为例探讨该模式指导国内社区护理的可行性,以求为护理同行了解应用人口健康促进模式提供良好的基础。孟宪梅 TAM Truong Donnelly 2008护理学杂志(外科版)2008,23,5:3
9The influence of nanotopography on cell behaviour through interactions with the extracellular matrix-A review显示文摘Nanotopography presents an effective physical approach for biomaterial cell manipulation mediated through material-extracellular matrix interactions.The extracellular matrix that exists in the cellular microenvironment is crucial for guiding cell behaviours,such as determination of integrin ligation and interaction with growth factors.These interactions with the extracellular matrix regulate downstream mechanotransductive pathways,such as rearrangements in the cytoskeleton and activation of signal cascades.Protein adsorption onto nanotopography strongly influences the conformation and distribution density of extracellular matrix and,therefore,subsequent cell responses.In this review,we first discuss the interactive mechanisms of protein physical adsorption on nanotopography.Secondly,we summarise advances in creating nanotopographical features to instruct desired cell behaviours.Lastly,we focus on the cellular mechanotransductive pathways initiated by nanotopography.This review provides an overview of the current state-of-the-art designs of nanotopography aiming to provide better biomedical materials for the future.Jiajun Luo Matthew Walker Yinbo Xiao Hannah Donnelly Matthew J.Dalby Manuel Salmeron-Sanchez 2022Bioactive Materials2022,7,9:3
10Anaerobic treatment of a chemical synthesis-based pharmaceutical wastewater in a hybrid upflow anaerobic sludge blanket reactor显示文摘Yalcin Askin Oktem Orhan Ince Paul Sallis Tom Donnelly Bahar Kasapgil Ince 2007Bioresource Technology2007,,5:2
11Tuberous sclerosis complex: renal imaging findings 显示文摘Casper KA Donnelly LF Chen B 2002Radiology2002,225,:2
12Randomized Controlled Trial of an Early Discharge Rehabilitation Service: The Belfast Community Stroke Trial显示文摘Michael Donnelly Michael Power Mary Russell Ken Fullerton 2004Stroke: Journal of the American Heart Association2004,,1:2
13Gastrointestinal and liver disease in patients with schizophrenia:A narrative review显示文摘Schizophrenia is a severe mental illness which can have a devastating impact onan individual’s quality of life. Comorbidities are high amongst patients and lifeexpectancy is approximately 15 years less than the general population. Despite thewell-known increased mortality, little is known about the impact of gastrointestinaland liver disease on patients with schizophrenia. We aimed to reviewthe literature and to make recommendations regarding future care. Literaturesearches were performed on PubMed to identify studies related to gastrointestinaland liver disease in patients with schizophrenia. High rates of chronic liverdisease were reported, with Non-Alcoholic Fatty Liver Disease being of particularconcern;antipsychotics and metabolic syndrome were contributing factors. Ratesof acute liver failure were low but have been associated with antipsychotic useand paracetamol overdose. Coeliac disease has historically been linked to schizophrenia;however, recent research suggests that a causal link is yet to be proven.Evidence is emerging regarding the relationships between schizophrenia andpeptic ulcer disease, inflammatory bowel disease and irritable bowel syndrome;clinical vigilance regarding these conditions should be high. Patients with schizophreniapoorly engage with bowel cancer screening programmes, leading to latediagnosis and increased mortality. Clozapine induced constipation is a significantissue for many patients and requires close monitoring. There is a significantburden of gastrointestinal and liver disease amongst patients with schizophrenia.Better levels of support from all members of the medical team are essential toensure that appropriate, timely care is provided.Rebecca K Grant William M Brindle Mhairi C Donnelly Pauline M McConville Thomas G Stroud Lorenzo Bandieri John N Plevris 2022World Journal of Gastroenterology2022,28,38:2
14Heterologous protection against influenza by injection of DNA encod ing a viral protein显示文摘Ulmer J B Donnelly J J Parker S 1993Science1993,259,5102:2
15Minimally Invasive Approach Provides at Least Equivalent Results for Surgical Correction of Mitral Regurgitation: A Propensity Matched Comparison显示文摘Andrew B. Goldstone Pavan Atluri Wilson Y. Szeto Alen Trubelja Jessica L. Howard John W. MacArthur Craig Newcomb Joseph P. Donnelly Dale M. Kobrin Mary A. Sheridan Christiana Powers Robert C. Gorman Joseph H. Gorman Alberto Pochettino Joseph E. Bavaria Mi 2012The Journal of Thoracic and Cardiovascular Surgery2012,,:2
16New users of metformin are at low risk of incident cancer:a cohort study among people with type 2 diabetes显示文摘Libby G Donnelly LA Donnan PT Diabetes Care0,,:2
17Late syn-to post-collisional magmatism in Madagascar:The genesis of the Ambalavao and Maevarano Suites显示文摘The East African Orogen involves a collage of Proterozoic microcontinents and arc terranes that became wedged between older cratonic blocks during the assembly of Gondwana.The Ediacaran-Cambrian Ambalavao and Maevarano Suites in Madagascar were emplaced during the waning orogenic stages and consist of weakly deformed to undeformed plutonic rocks and dykes of mainly porphyritic granite but also gabbro,diorite and charnockite.U-Pb geochronological data date emplacement of the Ambalavao Suite to between ca.580 Ma and 540 Ma and the Maevarano Suite to between ca.537 Ma and522 Ma.Major and trace element concentrations are consistent with emplacement in a syn-to postcollisional tectonic setting as A-type(anorogenic) suites.Oxygen(δ^(18)O of 5.27‰-7.45‰) and hafnium(ε(Hf)(t) of-27.8 to-12.3) isotopic data from plutons in the Itremo and Antananarivo Domains are consistent with incorporation of an ancient crustal source.More primitive δ^(18)O(5.27‰-5.32‰) andε(Hf)(t)(+0.0 to+0.2) isotopic values recorded in samples collected from the Ikalamavony Domain demonstrate the isotopic variation of basement sources present in the Malagasy crust.The Hf isotopic composition of Malagasy zircon are unlike more juvenile Ediacaran-Cambrian zircon sou rces elsewhere in the East African Orogen and,as such,Madagascar represents a distinct and identifiable detrital zircon source region in Phanerozoic sedimentary provenance studies.Taken together,these data indicate that high-T crustal anatexis,crustal assimilation and interaction of crustal material with mantle-derived melts were the processes operating during magma emplacement.This magmatism was coeval with polyphase deformation throughout Madagascar during the amalgamation of Gondwana and magmatism is interpreted to reflect lithospheric delamination of an extensive orogenic plateau.Donnelly B.Archibald Alan S.Collins John D.Foden Justin L.Payne Peter Holden Théodore Razakamanana 2019Geoscience Frontiers2019,10,6:2
18Comparison of the micro- and macro-vascular effects of glimepiride and gliclazide in metformin-treated patients with Type 2 diabetes: a double-blind, crossover study显示文摘Dhindsa P Davis K R Donnelly R 2003Br J Clin Pharmacol2003,55,6:2
19Isoflavonoids of Mildbraedeodendron excelsa 显示文摘Meegan M J Donnelly D M X 1975P hytochemistry1975,14,10:2
20Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation.David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira 2012World Journal of Gastroenterology2012,18,12:2
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