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| 1 | Endocrine radionuclide scintigraphy with fusion single photon emission computed tomography/computed tomography显示文摘AIM: To review the benefits of single photon emission computed tomography(SPECT)/computed tomography(CT) hybrid imaging for diagnosis of various endocrine disorders.METHODS: We performed MEDLINE and Pub Med searches using the terms: 'SPECT/CT'; 'functional anatomic mapping'; 'transmission emission tomography'; 'parathyroid adenoma'; 'thyroid cancer'; 'neuroendocrine tumor'; 'adrenal'; 'pheochromocytoma'; 'paraganglioma'; in order to identify relevant articles published in English during the years 2003 to 2015. Reference lists from the articles were reviewed to identify additional pertinent articles. Retrieved manuscripts(case reports, reviews, meta-analyses and abstracts) concerning the application of SPECT/CT to endocrine imaging were analyzed to provide a descriptive synthesis of the utility of this technology.RESULTS: The emergence of hybrid SPECT/CT camera technology now allows simultaneous acquisition of combined multi-modality imaging, with seamless fusion of three-dimensional volume datasets. The usefulness of combining functional information to depict the biodistribution of radiotracers that map cellular processes of the endocrine system and tumors of endocrine origin, with anatomy derived from CT, has improved the diagnostic capability of scintigraphy for a range of disorders of endocrine gland function. The literature describes benefits of SPECT/CT for ^(99m)Tc-sestamibi parathyroid scintigraphy and ^(99m)Tc-pertechnetate thyroid scintigraphy, ^(123)I- or ^(131)I-radioiodine for staging of differentiated thyroid carcinoma, ^(111)In- and ^(99m)Tclabeled somatostatin receptor analogues for detection of neuroendocrine tumors, ^(131)I-norcholesterol(NP-59) scans for assessment of adrenal cortical hyperfunction, and ^(123)I- or ^(131)I-metaiodobenzylguanidine imaging for evaluation of pheochromocytoma and paraganglioma.CONCLUSION: SPECT/CT exploits the synergism between the functional information from radiopharmaceutical imaging and anatomy from CT, translating to improved diagnostic accuracy and meaningful impact on patient care. | Ka-Kit Wong Arpit Gandhi Benjamin L Viglianti Lorraine M Fig Domenico Rubello Milton D Gross | 2016 | World Journal of Radiology2016，8，6： | 3 |
| 2 | Heme oxygenase-1 expression in the left atrial myocardium of patients with chronic atrial fibrillation related to mitral valve disease: its regional relationship with structural remodeling 显示文摘 | DOMENICO C M D SERGIO C M D ROBERTA M B | 2008 | Human Pathology2008，39，： | 1 |
| 3 | Towards gene therapy for deafness显示文摘 | Di Domenico M Ricciardi C Martone T Mazzarella N. Cassandro C. Chiarella G. D'Angelo L. Cassandro E | | 0，，： | 1 |
| 4 | Development and validation of fast real-time PCR assays for species identification in raw and cooked meat mixtures显示文摘 | CAMMA C DOMENICO M D MONACO F | 2012 | Food Control2012，23，： | 1 |
| 5 | The complete DNA sequence of the mitochondrial genome of Podospora anserina 显示文摘 | CUMMINGS D J MCNALLY K L DOMENICO J M | 1990 | Cun~nt genetics1990，17，5： | 1 |
| 6 | Fertility rate evaluation by laparoscopic approach in the experimental animal显示文摘 | Romano D Terzano M G Di Domenico M | 2002 | Clinical and experimental obstetrics & gynecology2002，29，2： | 1 |
| 7 | Molecular asymmetry in the 8-cell stage Xenopus tropicalis embryo described by single blastomere transcript sequencing显示文摘 | DE DOMENICO E OWENS N D GRANT I M | 2015 | Dev Biol2015，408，2： | 1 |
| 8 | Development andvalidation of fast Real-Time PCR assays for species identification inraw and cooked meat mixtures显示文摘 | CAMMA C DOMENICO M D MONACO F | 2012 | Food Control2012，23，2： | 1 |
| 9 | Water from low-permeability sediments and land subsidence显示文摘 | Domenico P A Mifflin M D | 1965 | Water Resources Research1965，1，4： | 1 |
| 10 | Social econ- omy involvemem in public service delivery:Community engag- ement and accountability显示文摘 | DOMENICO M D TRACEY P HUAUGH H | 2009 | Regional Studies2009，43，7： | 1 |
| 11 | A survey on MAC strategies for cognitive radio networks显示文摘 | DOMENICO A STRINATI E C BENEDETTO M G D | 2012 | IEEE Communica- tions Surveys & Tutorials2012，14，1： | 1 |
| 12 | Papillary cystic and solid tumors of the pancreas: A pancreatic embryonic tumor? Studies of three cases and cumulative review of the world's literature? 显示文摘 | Mao C Guvendi M Domenico D R | 1995 | Surgery1995，118，5： | 1 |
| 13 | Papillary cystic and solid tumors of the pancreas:a pancreatic embryonic tumor? Studies of three cases and cumulative review of the world's literature显示文摘 | MAO C GUVENDI M DOMENICO D R | 1995 | Surgery1995，118，： | 1 |
| 14 | Ferroelectric harmonic generator and the large-signal microwave characteristics of a ferroelectric ceramic显示文摘 | DOMENICO M D JOHNSON D A PANTELL R H | 1962 | J Appl Phys1962，33，： | 1 |
| 15 | Steroid receptor regulation of epidermal growth factor signaling through src in breast and prostate cancer cells:Steroid antagonist action显示文摘 | Migliccio A Domenico M D Castoria G | 2005 | Cancer Res2005，65，10： | 1 |
| 16 | A survey on MAC strategies for cognitive radio networks显示文摘 | Domenico A D Strinati E C and Benedetto M G D | 2012 | IEEE Journal on Communications Surveys and Tutorials2012，14，1： | 1 |
| 17 | Reproductive biology and pollinator limitation in a deceptive orchid,Serapias vomeracea(Orchidaceae)显示文摘 | Pellegrino G Domenico D Noce M E | 2005 | Plant Species Biology2005，20，： | 1 |
| 18 | Papillary cystic and solid tumors of the pancreas:apancreatic embryonic tumor?Studies of three cases and cumulative review of the worlds literature显示文摘 | Mao C Guvendi M Domenico D R | 1995 | Surgery1995，118，5： | 1 |
| 19 | Papillary cyst-ic and solid tumors of the pancreas : a pancreatic embryon-ic tumor? Studies of three cases and cumulative review ofthe worlds literature显示文摘 | Mao C Guvendi M Domenico D R ef al | 1995 | Surgery1995，118，5： | 1 |
| 20 | The molecular mechanism of hepcidin-mediated ferrportin down-regulation 显示文摘 | Domenico I D Ward D M Langelier C | 2007 | Mol Biol Cell2007，18，7： | 1 |
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