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1003篇 您的检索式:作者名="DOBBS"
    题名 作者 年代 出处 被引量
1The low FODMAP diet improves gastrointestinal symptoms in patients with irritable bowel syndrome: a prospective study显示文摘R. H. Roest B. R. Dobbs B. A. Chapman B. Batman L. A. O’Brien J. A. Leeper C. R. Hebblethwaite R. B. Gearry 2013Int J Clin Pract2013,,9:7
2脊髓损伤后肠道功能障碍显示文摘回顾结肠、直肠动力和排便的基本生理学特征 ,阐述脊髓损伤对排便的影响 ,讨论目前临床上的治疗措施 ,并提出新的治疗和研究方向。AC Lynch AA ntony BR Dobbs FA Frizelle 王红星 2002中国康复理论与实践2002,8,3:7
3基于Medipix的谱微CT(英文)显示文摘自从几十年前豪斯菲尔德因其突破性工作而赢得诺贝尔奖以来,X线CT已经被广泛的应用到了临床前以及临床应用,并产生了海量的灰度断层图像。由于其固有的光子计数问题涉及到较高的辐射剂量,这些灰度断层图像的软组织对比度差,经常难以提供一些关键性的细节而满足诊断的需要。从物理的角度来看,X线的谱是多能的,获得多能CT(亦被称为谱CT,真彩色CT)图像是可行的。这种谱图像提供了强有力的新诊断信息。近年来,新兴的Medipix技术提供了一种准确而快速的高分辨率能量选择的X线检测技术。本文将以我们小组的研究结果为重点来综述基于Medipix的谱微CT的研究进展。主要内容包括:先进的MediPix检测器,商业化MARS谱微CT的系统与方法,以及混合谱微CT的设计以及彩色扩散现象。James Bennett Raja Amir Bruce Dobbs 牟轩沁 魏彪 Anthony Butler Phillip Butler 2012CT理论与应用研究(中英文)2012,21,4:4
4人参减少 γ射线照射的淋巴细胞微核量(英文)显示文摘目的 评价中国人参对减少辐射诱导的人周围血 G0 期淋巴细胞 (PBL)微核量的作用。方法 采用细胞因子阻滞的微核法检测健康志愿者的血标本。体外 1 37Cs照射之前 ,每份血标本的单个核细胞培养以不同浓度 (0~ 2 0 0 0μg· m l- 1 )的人参根水提取物孵育 2 4 h。结果 (1)在 0 Gy时 ,每 10 0 0个双核 (BN )细胞的微核量是 11.3± 2 .7,人参水提取物≥ 5 0 0μg· ml- 1 时微核量下降 ,但微核量和人参水提取物的浓度之间的差异是显著的。 (2 )单独射线照射显著增加微核量 ,当暴露于 1Gy的照射时 ,随着培养介质中人参水提取物浓度的增加 ,微核量呈显著的线性降低 (R2 =0 .0 5 ,P =0 .0 0 2 ) ;对暴露于 1Gy辐射诱导的微核量 ,人参水提取物浓度在 15 0 0μg· m l- 1 时减少 4 6 .6 % ,浓度在 2 0 0 0μg·m l- 1时减少 5 7.6 % ;对暴露于 2 Gy辐射诱导的微核量的减少呈更强的线性相关 (R2 =0 .7,P=0 .0 0 0 1) ;(3)微核数据分析的结果呈现出与 Poisson模型相关的过度离散趋势。结果表明 :(1)人参水提取物浓度达 2 0 0 0 μg· ml- 1时 ,对 PBL 细胞毒作用无明显影响 ;(2 )人参水提取物浓度在 5 0 0 μg· ml- 1和 2 0 0 0 μg· ml- 1之间时 ,对抗 1 37Cs照射诱导的 MN发挥保护作用。李同光 Ron R Allison Kevin F O'Brien Prabhaker G Khazanie Larry J Dobbs Jr. Peter J Kragel 2004新乡医学院学报2004,21,3:3
5Vacuum electronic high power terahertz sources显示文摘BOOSKE J DOBBS R JOYE C 0,,01:3
6G-Quadruplex(G4) Motifs in the Maize(Zea mays L.) Genome Are Enriched at Specific Locations in Thousands of Genes Coupled to Energy Status,Hypoxia,Low Sugar,and Nutrient Deprivation显示文摘The G-quadruplex(G4) elements comprise a class of nucleic acid structures formed by stacking of guanine base quartets in a quadruple helix.This G4 DNA can form within or across single-stranded DNA molecules and is mutually exclusive with duplex B-form DNA.The reversibility and structural diversity of G4 s make them highly versatile genetic structures,as demonstrated by their roles in various functions including telomere metabolism,genome maintenance,immunoglobulin gene diversification,transcription,and translation.Sequence motifs capable of forming G4 DNA are typically located in telomere repeat DNA and other non-telomeric genomic loci.To investigate their potential roles in a large-genome model plant species,we computationally identified 149,988 non-telomeric G4 motifs in maize(Zea mays L.,B73 AGPv2),29%of which were in non-repetitive genomic regions.G4 motif hotspots exhibited non-random enrichment in genes at two locations on the antisense strand,one in the 5'UTR and the other at the 5'end of the first intron.Several genic G4 motifs were shown to adopt sequence-specific and potassium-dependent G4 DNA structures in vitro.The G4 motifs were prevalent in key regulatory genes associated with hypoxia(group VII ERFs),oxidative stress(DJ-1/GATase1),and energy status(AMPK/SnRK) pathways.They also showed statistical enrichment for genes in metabolic pathways that function in glycolysis,sugar degradation,inositol metabolism,and base excision repair.Collectively,the maize G4 motifs may represent conditional regulatory elements that can aid in energy status gene responses.Such a network of elements could provide a mechanistic basis for linking energy status signals to gene regulation in maize,a model genetic system and major world crop species for feed,food,and fuel.Carson M.Andorf Mykhailo Kopylov Drena Dobbs Karen E.Koch M.Elizabeth Stroupe Carolyn J.Lawrence Hank W.Bass 2014Journal of Genetics and Genomics2014,41,12:2
7The past,present,and future of single-port urology?显示文摘In this manuscript,Ju et al.1 sought to compare short-term perioperative outcomes between extraperitoneal robotic single-port radical prostatectomy(epR-spRP)and extraperitoneal robotic multiport radical prostatectomy(epR-mpRP)utilizing a multi-channel laparoscopic port and the da Vinci Si robotic platform.In this comparison,several potential advantages of single-site surgery including median hospital stay,pain scores,and surgical scar cosmesis favored the spRP arm.While this study represents a relatively small sample size in both cohorts,the authors should be commended for a novel approach to executing a single-site robotic prostatectomy without the availability of the da Vinci Si platform.Luca A Morgantini Simone Crivellaro Ryan W Dobbs 2021Asian Journal of Andrology2021,23,6:2
8A widespread fungistasis in soils显示文摘Dobbs C G Hinson W H 1953Nature1953,172,:2
9Comparison of two kinds of Biolog microplates (GN and ECO) in their ability to distinguish among aquatic microbial communities显示文摘Keun-Hyung Choi Fred C Dobbs 1999Journal of Microbiological Methods1999,,3:2
10Measure- ment of functional microcirculatory geometry and velocity distributions using automated image analysis 显示文摘Dobbe J G G Streekstra G J Atasever B 2008Medical Biologic Engineer Computer2008,46,7:1
11Angiogeresis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia 显示文摘Dobbs SP Hewet PW Johnson IR 1997Br J Cancer1997,76,:1
12Quantitative detection of increasing HIV type 1 antibodies after seroconversion:a simple assay for detecting recent HIV infectiong and estimating incidence显示文摘Parekh BS Kennedy MS Dobbs T 2002AIDS Res Hum retroviruses2002,18,:1
13Quantitative detection of increasing HIV type 1 antibodies after seroconversion : a sim- ple assay for detecting recent HIV infection and estimating inci- dence显示文摘Parekh BS Kennedy MS Dobbs T 2002AIDS Res Hum Retroviruses2002,18,:1
14Hospice attitudes among assisted living and nursing home administrators,and the long-term care hospice attitudes scale显示文摘Dobbs DJ Hanson L Zimmerman S 2006J Palliat Med2006,9,6:1
15Low density lipoprotein-and high density lipoprotein-mediatedsignal transduction and exocytosis in alveolar type II cells显示文摘Voyno-Yasenetskaya TA Dobbs LG Erickson SK Hamilton RL 1993ProcNatl Acad Sci1993,90,9:1
16The ultraviolet sensitivity of Kevlar 149 and teehnora fibres 显示文摘DOBB M G ROBSON R M ROBERTYS A H 1993Journal of Materials Science1993,28,3:1
17Bowel dysfunction followingspinal cord injury 显示文摘Lynch AC Antony A Dobbs BR 2001Spinal Cord2001,39,4:1
18A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation 显示文摘Dobbs TA Tainer JA Lees-Miller SP 2010DNA Repair2010,9,12:1
19The utility of laparoscopy in the diagnosis of acute appendicitis in women of reproductive age显示文摘Van Dalem R Bagshaw PF Dobbs BR 2003Surg Endosc2003,17,8:1
20A two-stage classifier for identification of protein-protein interface residues 显示文摘Changhui Yan Drena Dobbs Vasant Hoavar 2004Bioinformatics2004,20,1:1
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