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| 1 | Quality of life, physical performance and nutritional status in older patients hospitalized in a cardiology department显示文摘Objectives Quality of life(QoL) is a priority outcome in older adults suffering from cardiovascular diseases. Frailty and poor nutritional status may affect the QoL through mobility disorders and exhaustion. The objective of this study was to determine if physical frailty and nutritional status were associated with QoL, in older cardiology patients. Methods Cross sectional, observational study conducted in a cardiology department from a university hospital. Participants(n = 100) were aged 70 and older. Collected data included age, sex, cardiac diseases, New York Heart Association(NYHA) classification, comorbidities(Charlson Index) and disability. A Short Physical Performance Battery(SPPB), including walking speed assessment was performed;handgrip strength were measured as well as Fried’s frailty phenotype. Nutritional status was assessed using the Mini Nutritional Assessment(MNA) and Body Mass Index(BMI), inflammation by C-reactive protein(CRP). QoL was assessed using the EORTC–QLQ questionnaire. Univariate and multivariate analyses were performed to study the associations between all recorded parameters and QoL. Results In participants(mean age: 79.3 ± 6.7 years;male: 59%), Charlson index, arrhythmia, heart failure, NYHA class III-IV, MNA, disability, walking speed, SPPB score, frailty and CRP were significantly associated with QoL in univariate analysis. Multivariate analysis showed that NYHA class III-IV(P < 0.001), lower MNA score(P = 0.03), frailty(P < 0.0001), and higher CRP(P < 0.001) were independently associated with decreased QoL. Conclusions Frailty, nutritional status and inflammation were independently associated with poor QoL. Further studies are needed to assess the efficacy of nutritional and physical interventions on QoL in this population. | Matthieu Lilamand Mariannick Saintout Marie Vigan Astrid Bichon Laure Tourame Aurélie Brembilla Diet Bernard Iung Dominique Himbert Cédric Laouenan Agathe Raynaud-Simon | 2020 | Journal of Geriatric Cardiology2020，17，7： | 3 |
| 2 | Analysis of differentially expressed genes in nitric oxide exposed human monocytic cells 显示文摘 | Turpaev K Bouton C Diet A | 2005 | Free Radic Biol Med2005，38，10： | 1 |
| 3 | ACE and angiotensinogen gene genotypes and left ventricular mass in athletes显示文摘 | DIET F GRAF C MAHNKE N | 2001 | Eur J Clini Invest2001，31，： | 1 |
| 4 | ASTUTE: detecting a diffe- rent class of 'traffic anomalies 显示文摘 | SILVEIRA F DIeT C TAFT N | 2010 | ACM SIGCOMM Computer Communication Review2010，40，4： | 1 |
| 5 | Percutancous laser disc decompression under CT,and fluoscopic guidance:indications,technique,and clinical experinence显示文摘 | Gangi A Diete mann JL Ide C | 1996 | Scientifoc Exhibit1996，16，： | 1 |
| 6 | Tumors of the papilla of vater inadequate diagnostic impact of endoscopic biopsies taken perior to and following sphineterotomy显示文摘 | Menzel J Poremba C Diet K H | 1999 | Ann Oncol1999，10，10： | 1 |
| 7 | Analysis of a quantitative trait locus allele from wild soybean that increases seed protein concentration in soybean 显示文摘 | Sebolt A M Shoemakerb R C Diets B W | 2000 | Crop Science2000，40，： | 1 |
| 8 | Evaluation of soybean cultivars for resistance to sclerotinia stem rot in field environments显示文摘 | Kim H S Sneller C H Diets B W | 1999 | Crop Science1999，39，： | 1 |
| 9 | The GU-MACH study:the efface of 1-week omeprazole triple therapy on Helicobacter pylori infection in patients with gastric ulcer显示文摘 | Malfertheiner P Bayerdorffer E Diete U Gil J Lind T Misiuna P O'morain C Sipponen P Spiller RC Stesiewicz J Treichel H Ujszaszy L Unge P Zanten ST Zeijlon L | 1999 | Aliment Pharmacol Ther1999，13，6： | 1 |
| 10 | Signal quality of biometry in silicone oil-filled eyes using partial coherence laser interferometry 显示文摘 | Diet]ein TS Roessler G Luke C Dinslage S Roters S Jacobi PC | 2005 | J Cataract Refract Surg2005，31，5： | 1 |
| 11 | Characterization of a DNA sequence encoding the peroxisome proliferators activated receptor a in the chicken显示文摘 | Diet C Douaire M | 1999 | Poultry Science1999，78，： | 1 |
| 12 | A critical review of the genotoxic potential of electric and magnetic fields 显示文摘 | Mccann J Diet R F Rafferty C | 1993 | Mutat Res1993，297，： | 1 |
| 13 | Tumors of the papilla of vater inadequate diagnostic impact of endoscopic biopsies taken pefior to and following sphincterotomy 显示文摘 | Menzel J Poremba C Diet KH | 1999 | Ann Oncol1999，10，10： | 1 |
| 14 | A comprehensive genetic map of the mouse genome显示文摘 | Diet rich W F Miller J C Steen R G | 1996 | Nature1996，，380： | 1 |
| 15 | Tumors of the papilla of Vater inadequate diagnostic impact of endoscopic biopsies taken prior to and following sphincterotomy 显示文摘 | Menzel J Doremba C Diet KH | 1999 | Ann Oncol1999，10，10： | 1 |
| 16 | Effects of cinacalcet in renal transplant patients with hyperparathyroidism显示文摘 | Courbebaisse M Diet C Timsit MO | 2012 | Am J Nephrol2012，35，： | 1 |
| 17 | New imaging method for assessing pelvic foor biomechanics显示文摘 | Thyer I Shek C Diet Z HP | | 0，，02： | 1 |
| 18 | Prognostic relevance of MAPK expression in glioblastoma multiforme 显示文摘 | MAWRIN C DIETE S TREUHEIT T | 2003 | Int J Oncol2003，23，3： | 1 |
| 19 | Genetic diversity of oilseed Brassica napus germplasm based on restriction fragment length polymorphlsrns 显示文摘 | Diets B W Osbom T C | 1994 | Theoretical and Applied Genetics1994，88，2： | 1 |
| 20 | Relationship between stress, eating behavior, and obesity显示文摘 | Torres S J Diet M N Nowson C A | 2007 | Nutrition2007，23，1112： | 1 |
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