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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Treatment of inferior turbinate hypertrophy:a randomized clinical trial显示文摘 | Passali D Passali FM Damiani V | 2003 | Ann Otol Rhinol Laryngol2003，112，8： | 1 |
| 3 | P-glycoprotein,lung resistance-related protein and multidrugresistance-associated protein in de novo adult acute lymphoblastic leukemia显示文摘 | Damiani D Michelutti A Michieli M | 2002 | Br J Haematol2002，116，3： | 1 |
| 4 | Laser conditioning of KDP crystals using excimer and Nd:YAG lasers显示文摘 | Bertussi B Damiani D Pommies M | | 0，，： | 1 |
| 5 | Treatment of inferior turbinate hypertrophy:a randomized clinical trial显示文摘 | Passali D Passali FM Damiani V | 2003 | AnnOtol RhinolLaryngol2003，112，8： | 1 |
| 6 | Excimer laser conditioning of KDP:influence of the laser parameters and crystal orientation on the laser damage threshold显示文摘 | Damiani D Piombini H Plessis D | | 0，，： | 1 |
| 7 | Transversus abdominis plane block associated with locoregional anesthesia with a laparotenser for gynecologic surgery in an awake state显示文摘 | Pellegrino A Damiani GR Speciale D | 2013 | J Minim Invasive Gynecol2013，20，2： | 1 |
| 8 | Incidence of bacterial and fungal infections in newly diagnosed acute myeloid leukemia patients younger than 65 yr treated with induction regimens including fludarabine:retros-pective analysis of 224 cases显示文摘 | Damiani D | 2008 | Eur J Haematol2008，81，5： | 1 |
| 9 | Hyperglycemic acute crisis in type 1 diabetes mel- litus in youth 显示文摘 | DAMIANI D | 2008 | Arq Bras Endocrinol Metabol2008，52，2： | 1 |
| 10 | Adjuvant treatment with cyclosporin A increases the toxicity of chemotherapy for remission induction in acute non-lymphocytic leukemia 显示文摘 | Damiani D Michieli M Ermacora A | 1998 | Leukemia1998，12，8： | 1 |
| 11 | Biochemical and developmental evidence that oop- lasmic maturation of prepubertaI bovine oocytes is compromised显示文摘 | SALAMONE D F DAMIANI P FISSORE R A | 2001 | Biol Reprod2001，64，6： | 1 |
| 12 | Absolute and relative adrenal insufficiency in children with septic shock 显示文摘 | Pizarro CF Troster EJ Damiani D | 2005 | Crit Care Med2005，33，4： | 1 |
| 13 | Nitroxide radicals protect against DNA damage in rat epithelial cells induced by nitric oxide, nitroxyl anion and peroxynitrite显示文摘 | Fedeli D Damiani F Greci L | 2003 | Mutat Res2003，3，2： | 1 |
| 14 | P - glycoprotein(P - gp)and lung resistance - related protein(LRP) expression and function in leukaemic blast cells显示文摘 | Michieli M Damiani D Ermacora A | 1997 | Br J Haematol1997，96，2： | 1 |
| 15 | Caspofungin as first line therapy of pulmonary invasive fungal infections in32im-munocompromised patients with hematologic malignancies显示文摘 | Candoni A Mestroni R Damiani D | 2005 | Eur J Haematol2005，75，3： | 1 |
| 16 | CD56 and PGP expres- sion in acute myeloid leukemia: impact on clinical outcome显示文摘 | Raspadori D Damiani D Michiell M | 2012 | Haematologica2012，87，11： | 1 |
| 17 | Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina 显示文摘 | Damiani D Alexander J J O' ourke JR McManus M Jadhav AP Cepko CL | 2008 | J Neurosci2008，28，19： | 1 |
| 18 | Study of zirconocene and MAO interaction with SiO2 surfaces显示文摘 | Juan A Damiani D Pistonesi C | 2000 | Appl Suf Sei2000，161，3： | 1 |
| 19 | Molecular cytogenetic compa- rison of apocrine hyperplasia and apocrine carcinoma of the breast 显示文摘 | Jones C Damiani S Wells D | 2001 | Am J Pathol2001，158，1： | 1 |
| 20 | Incidence of bacterial and fungal infections in newly diagnosed acute myeloid leukemia patients younger than 65 yr treated with induction regimens including fludarabine:retrospective analysis of 224 cases显示文摘 | Malagola M Peli A Damiani D | | 0，，05： | 1 |
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