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| 1 | The AGL6-like gene OsMADS6 regulates floral organ and meristem identities in rice显示文摘Although AGAMOUS-LIKE6 (AGL6) MADS-box genes are ancient with wide distributions in gymnosperms and angiosperms, their functions remain poorly understood. Here, we show the biological role of the AGL6-1ike gene, OsMADS6, in specifying floral organ and meristem identities in rice (Oryza sativa L.). OsMADS6 was strongly ex- pressed in the floral meristem at early stages. Subsequently, OsMADS6 transcripts were mainly detectable in paleas, lodicules, carpels and the integument of ovule, as well as in the receptacle. Compared to wild type plants, osmads6 mutants displayed altered palea identity, extra glume-like or mosaic organs, abnormal carpel development and loss of floral meristem determinacy. Strikingly, mutation of a SEPALLATA (SEP)-like gene, OsMADS1 (LHS1), enhanced the defect of osmads6 flowers, and no inner floral organs or glume-like structures were observed in whorls 2 and 3 of osmadsl-z osmads6-1 flowers. Furthermore, the osmadsl-z osmads6-1 double mutants developed severely indetermi- nate floral meristems. Our finding, therefore, suggests that the ancient OsMADS6 gene is able to specify 'floral state' by determining floral organ and meristem identities in monocot crop rice together with OsMADS1. | Haifeng Li Wanqi Liang Ruidong Jia Changsong Yin Jie Zong Hongzhi Kong Dabing Zhang | 2010 | Cell Research2010，20，3： | 33 |
| 2 | Development of japonica Photo-Sensitive Genic Male Sterile Rice Lines by Editing Carbon Starved Anther Using CRISPR/Cas9显示文摘Rice is one of the most important crops as it supports over25%of total caloric intake for humans(Kusano et al.,2015).The world population reached 7.3 billion in 2015 and is projected to reach 8.5 billion in 2030(Word Population Prospects:2015 Revision).To meet the food demands for the everincreasing population with limited arable land,scarce | Quanlin Li Dabing Zhang Mingjiao Chen Wanqi Liang Jiaojun Wei Yiping Qi Zheng Yuan | 2016 | Journal of Genetics and Genomics2016，43，6： | 26 |
| 3 | Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells显示文摘外长的 dopaminergic 神经原(DA 神经原) 的移植是为治疗 Parkinson 的疾病(PD ) 的一条有希望的途径。然而,主要跌倒块是施主 DA 神经原的可靠来源的缺乏。这里,我们证明五 transcriptional 因素 Mash1, Ngn2, Sox2, Nurr1,和 Pitx3 的联合直接并且有效地装改编人成纤维细胞进 DA 像神经原的房间。为为 DA 神经原的各种各样的标记积极的染色的 reprogrammed 房间。他们也显示出典型 DA 举起和生产性质。而且,他们展出了 DA 神经原特定的 electrophysiological 侧面。最后,他们在一个老鼠 PD 模型提供了征兆的地势。因此,我们的直接 reprogrammed DA 像神经原的房间是为 PD 的房间代替治疗的有希望的来源。 | Xinjian Liu Fang Li Elizabeth A Stubblefield Barbara Blanchard Toni L Richards Gaynor A Larson Yujun He Qian Huang Aik-Choon Tan Dabing Zhang Timothy A Benke John R Sladek Nancy R Zahniser Chuan-Yuan Li | 2012 | Cell Research2012，22，2： | 14 |
| 4 | Interactions of OsMADS1 with Floral Homeotic Genes in Rice Flower Development显示文摘在繁殖开发期间,米饭植物开发决定最后的谷物收益的唯一的花器官。OsMADS1,象 SEPALLATA 一样疯盒子的基因之一,被解开了玩关键角色 inrice 花的机关身份说明和花的分裂组织确定性。然而,在调整花开发与另外的花的 homeotic 基因位于 OsMADS1 的相互作用下面的分子的机制 remainslargely 逃犯。在这个工作,我们在他们的蛋白质之中与物理相互作用一起与 B- , C- ,和 D 班基因学习了 OsMADS1 的基因相互作用。我们证明在 OsMADS1 和 OsMADS3 之间的物理、基因的相互作用为花的分裂组织活动维护和机关身份说明是必要的;当 OsMADS1 身体上并且遗传上在调整花的分裂组织确定性和 suppressingspikelet 分裂组织回复与 OsMADS58 交往时。我们提供了重要基因证据在花开发期间支持二米饭 C 班基因(OsMADS3 和 OsMADS58 ) 的 neofunctionalization。基因表示介绍和量的 RT-PCR 分析进一步表明 OsMADS1 影响涉及发信号的花的身份和荷尔蒙的许多基因的表达式,并且染色质 immunoprecipitation (芯片)-PCR 试金进一步证明 OsMADS17 是 OsMADS1 的直接目标基因。一起拿,这些结果表明 OsMADS1 在指定米饭有多样化的规章的功能花的机关和分裂组织身份,可能通过它和不同花的 homeotic 管理者的基因、物理的相互作用。 | Yun Hu Wanqi Liang Changsong Yin Xuelian Yang Baozhe Ping Anxue Li Ru Jia Mingjiao Chen Zhijing Luo Qiang Cai Xiangxiang Zhao Dabing Zhang Zheng Yuan | 2015 | Molecular Plant2015，8，9： | 10 |
| 5 | Development of genome-wide insertion/deletion markers in rice based on graphic pipeline platform显示文摘DNA markers play important roles in plant breeding and genetics.The Insertion/Deletion(InDel) marker is one kind of co-dominant DNA markers widely used due to its low cost and high precision.However,the canonical way of searching for InDel markers is time-consuming and laborintensive.We developed an end-to-end computational solution(InDel Markers Development Platform,IMDP) to identify genome-wide InDel markers under a graphic pipeline environment.IMDP constitutes assembled genome sequences alignment pipeline(AGA-pipe) and next-generation resequencing data mapping pipeline(NGS-pipe).With AGA-pipe we are able to identify 12,944 markers between the genome of rice cultivars Nipponbare and 93-11.Using NGS-pipe,we reported 34,794 InDels from re-sequencing data of rice cultivars Wu-Yun-Geng7 and Guang-Lu-Ai4.Combining AGApipe and NGS-pipe,we developed 205,659 InDels in eight japonica and nine indica cultivars and 2,681 InDels showed a subgroup-specific pattern.Polymerase chain reaction(PCR)analysis of subgroup-specific markers indicated that the precision reached 90%(86 of 95).Finally,to make them available to the public,we have integrated the InDels/markers information into a website(Rice InDel Marker Database,RIMD,http://gffzz71b3756633b74a6ehff569qfpopq06pxk.ffgz.tsg.suse.edu.cn/).The application of IMDP in rice will facilitate efficiency for development of genome-wide InDel markers,in addition it can be used in other species with reference genome sequences and NGS data. | Yang L Xiao Cui Rui Li Piaopiao Huang Jie Zong Danqing Yao Gang Li Dabing Zhang Zheng Yuan | 2015 | Journal of Integrative Plant Biology2015，57，11： | 9 |
| 6 | Regulatory network and genetic interactions established by OsMADS34 in rice inflorescence and spikelet morphogenesis显示文摘Grasses display highly diversified inflorescence architectures that differ in the arrangement of spikelets and flowers and determine cereal yields. However, the molecular basis underlying grass inflorescence morphogenesis remains largely unknown. Here we investigate the role of a functionally diversified SEPALLATA MADS-box transcription factor, OsMADS34, in regulating rice(Oryza sativa L.)inflorescence and spikelet development. Microarray analysis showed that, at the very early stages of inflorescence formation, dysfunction of OsMADS34 caused altered expression of 379 genes that are associated with protein modification and degradation, transcriptional regulation,signaling and metabolism activity. Genetic analysis revealed that OsMADS34 controls different aspects of inflorescence structure, branching and meristem activity synergistically with LAX PANICLE1(LAX1) and FLORAL ORGAN NUMBER4(FON4), as evidenced by the enhanced phenotypes of osmads34 lax1 and osmads34 fon4 compared with the single mutants. Additionally, double mutant between osmads34 and the sterile lemma defective mutant elongated empty glume(ele) displayed an enhanced phenotype, that is,longer and wider sterile lemmas that were converted into lemma/palea-like organs, suggesting that ELE and OsMADS34 synergistically control the sterile lemma development. OsMADS34 may act together with OsMADS15 in controlling sterile lemma development. Collectively, these findings provide insights into the regulatory function of OsMADS34 in rice inflorescence and spikelet development. | Qingcai Meng Xiaofeng Li Wanwan Zhu Li Yang Wanqi Liang Ludovico Dreni Dabing Zhang | 2017 | Journal of Integrative Plant Biology2017，59，9： | 5 |
| 7 | Full-duplex light communication with a monolithic multicomponent system显示文摘A monolithic multicomponent system is proposed and implemented on a III-nitride-on-silicon platform,whereby two multiple-quantum-well diodes(MQW-diodes)are interconnected by a suspended waveguide.Both MQW-diodes have an identical low-In-content InGaN/Al0.10Ga0.90N MQW structure and are produced by the same fabrication process flow.When appropriately biased,both MQW-diodes operate under a simultaneous emission-detection mode and function as a transmitter and a receiver at the same time,forming an in-plane full-duplex light communication system.Real-time full-duplex audio communication is experimentally demonstrated using the monolithic multicomponent system in combination with an external circuit. | Yongjin Wang Xin Wang Bingcheng Zhu Zheng Shi Jialei Yuan Xumin Gao Yuhuai Liu Xiaojuan Sun Dabing Li Hiroshi Amano | 2018 | Light(Science & Applications)2018，7，1： | 5 |
| 8 | Room-temperature continuous-wave electrically pumped InGaN/GaN quantum well blue laser diode directly grown on Si显示文摘Current laser-based display and lighting applications are invariably using blue laser diodes(LDs)grown on freestanding GaN substrates,which are costly and smaller in size compared with other substrate materials.1–3 Utilizing less expensive and large-diameter Si substrates for hetero-epitaxial growth of indium gallium nitride/gallium nitride(InGaN/GaN)multiple quantum well(MQW)structure can substantially reduce the cost of blue LDs and boost their applications.To obtain a high crystalline quality crack-free GaN thin film on Si for the subsequent growth of a blue laser structure,a hand-shaking structure was formed by inserting Al-composition step down-graded AlN/AlxGa1−xN buffer layers between GaN and Si substrate.Thermal degradation in InGaN/GaN blue MQWs was successfully suppressed with indium-rich clusters eliminated by introducing hydrogen during the growth of GaN quantum barriers(QBs)and lowering the growth temperature for the p-type AlGaN/GaN superlattice optical cladding layer.A continuous-wave(CW)electrically pumped InGaN/GaN quantum well(QW)blue(450 nm)LD grown on Si was successfully demonstrated at room temperature(RT)with a threshold current density of 7.8 kA/cm^(2). | Yi Sun Kun Zhou Meixin Feng Zengcheng Li Yu Zhou Qian Sun Jianping Liu Liqun Zhang Deyao Li Xiaojuan Sun Dabing Li Shuming Zhang Masao Ikeda Hui Yang | 2018 | Light(Science & Applications)2018，7，1： | 5 |
| 9 | Monolithic integration of MoS2-based visible detectors and GaN-based UV detectors显示文摘With the increasing demand for high integration and multi-color photodetection for both military and civilian applications, the research of multi-wavelength detectors has become a new research hotspot. However, current research has been mainly in visible dual-or multi-wavelength detectors, while integration of both visible light and ultraviolet(UV) dual-wavelength detectors has rarely been studied. In this work, large-scale and high-quality monolayer MoS2 was grown by the chemical vapor deposition method on transparent free-standing GaN substrate. Monolithic integration of MoS2-based visible detectors and GaN-based UV detectors was demonstrated using common semiconductor fabrication technologies such as photolithography, argon plasma etching, and metal deposition. High performance of a 280 nm and 405 nm dual-wavelength photodetector was realized.The responsivity of the UV detector reached 172.12 A/W, while that of the visible detector reached 17.5 A/W.Meanwhile, both photodetectors achieved high photocurrent gain, high external quantum efficiency, high normalized detection rate, and low noise equivalent power. Our study extends the future application of dual-wavelength detectors for image sensing and optical communication. | YOU WU ZHIWEN LI KAH-WEE ANG YUPING JIA ZHIMING SHI ZHI HUANG WENJIE YU XIAOJUAN SUN XINKE LIU DABING LI | 2019 | Photonics Research2019，7，10： | 4 |
| 10 | Investigation of CRISPR/Cas9-induced SD1 rice mutants highlights the importance of molecular characterization in plant molecular breeding显示文摘Although Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR)/CRISPR-associated 9(Cas9)system has been widely used for basic research in model plants,its application for applied breeding in crops has faced strong regulatory obstacles,due mainly to a poor understanding of the authentic output of this system,particularly in higher generations.In this study,different from any previous studies,we investigated in detail the molecular characteristics and production performance of CRISPR/Cas9-generated SD1(semi-dwarf 1)mutants from T2 to T4 generations,of which the selection of T1 and T2 was done only by visual phenotyping for semidwarf plants.Our data revealed not only on-and off-target mutations with small or lager indels but also exogenous elements in T2 plants.All indel mutants passed stably to T3 or T4 without additional modifications independent on the presence of Cas9,while some lines displayed unexpected hereditary patterns of Cas9 or some exogenous elements.In addition,effects of various SD1 alleles on rice height and yield differed depending on genetic backgrounds.Taken together,our data showed that the CRISPR/Cas9 system is effective in producing homozygous mutants for functional analysis,but it may be not as precise as expected in rice,and that early and accurate molecular characterization and screening must be carried out for generations before transitioning of the CRISPR/Cas9 system from laboratory to field. | Sukumar Biswas Jiaqi Tian Rong Li Xiaofei Chen Zhijing Luo Mingjiao Chen Xiangxiang Zhao Dabing Zhang Staffan Persson Zheng Yuan Jianxin Shi | 2020 | Journal of Genetics and Genomics2020，47，5： | 4 |
| 11 | Construction of van der Waals substrates for largely mismatched heteroepitaxy systems using first principles显示文摘The high density of defects induced by large strains in largely mismatched heteroepitaxy systems, such as AlN and GaN, because of the large lattice and thermal mismatch between substrates and epilayers is the bottleneck problem. Graphene-assisted van der Waals(vdW) heteroepitaxy offers a new opportunity to resolve this problem. However, it suffers from the difficulty of nucleation. Here we theoretically assess the effects of five 2D materials for vdW heteroepitaxy of AlN and GaN, including graphene, hBN, MoS2, gC3N, and gC3N4, and provide physical insights using first-principle calculations. MoS2 and gC3N exhibit significant potential to overcome the shortcomings of graphene owing to their appropriate binding strengths and Al(or Ga)diffusion barriers. Moreover, the interface behavior between the epilayers and the substrates are carefully analyzed. Our findings are helpful not only for obtaining high-quality AlN and GaN films but also for developing new criterions to discover effective 2D materials for vdW heteroepitaxy. | ZhiMing Shi XiaoJuan Sun YuPing Jia XinKe Liu ShanLi Zhang ZhanBin Qi DaBing Li | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，12： | 3 |
| 12 | Quantum engineering of non-equilibrium efficient p-doping in ultra-wide band-gap nitrides显示文摘Ultra-wide band-gap nitrides have huge potential in micro-and optoelectronics due to their tunable wide band-gap,high breakdown field and energy density,excellent chemical and thermal stability.However,their application has been severely hindered by the low p-doping efficiency,which is ascribed to the ultrahigh acceptor activation energy originated from the low valance band maximum.Here,a valance band modulation mode is proposed and a quantum engineering doping method is conducted to achieve high-efficient p-type ultra-wide band-gap nitrides,in which GaN quantum-dots are buried in nitride matrix to produce a new band edge and thus to tune the dopant activation energy.By non-equilibrium doping techniques,quantum engineering doped AIGaN:Mg with Al content of 60%is successfully fabricated.The Mg activation energy has been reduced to about 21 meV,and the hole concentration reaches higher than 10^(18)cm^(-3)at room temperature.Also,similar activation energies are obtained in AIGaN with other Al contents such as 50%and 70%;indicating the universality of the quantum engineering doping method.Moreover,deep-ultraviolet light-emission diodes are fabricated and the improved performance further demonstrates the validity and merit of the method.With the quantum material growth techniques developing,this method would be prevalently available and tremendously stimulate the promotion of ultra-wide band-gap semiconductor-based devices. | Ke Jiang Xiaojuan Sun Zhiming Shi Hang Zang Jianwei Ben Hui-Xiong Deng Dabing Li | 2021 | Light(Science & Applications)2021，10，4： | 3 |
| 13 | Review on the Progress of AlGaN-based Ultraviolet Light-Emitting Diodes显示文摘AlGaN-based materials have exhibited considerable potential for fabricating ultraviolet(UV)light-emitting diodes(LEDs)owing to their direct,wide,and adjustable energy bandgap.AlGaN-based devices have extensive appli-cability owing to their stable physico-chemical properties.With decades of research effort,significant progress has been achieved in enhancing the working efficiency of AlGaN-based LEDs by optimizing the crystalline qual-ity,doping efficiency,and device design.In this review,methods to obtain high-quality AlGaN-based materials,achieve high doping efficiency,and design UV-LED structures are summarized and discussed.Finally,the issues that need to be addressed in AlGaN-based UV-LED devices are highlighted. | Yuxuan Chen Jianwei Ben Fujun Xu Jinchai Li Yang Chen Xiaojuan Sun Dabing Li | 2021 | Fundamental Research2021，1，6： | 3 |
| 14 | Polarization-enhanced AlGaN solar-blind ultraviolet detectors显示文摘AlGaN solar-blind ultraviolet detectors have great potential in many fields,although their performance has not fully meet the requirements until now.Here,we proposed an approach to utilize the inherent polarization effect of AlGaN to improve the detector performance.AlGaN heterostructures were designed to enhance the polarization field in the absorption layer,and a high built-in field and a high electron mobility conduction channel were formed.As a result,a high-performance solar-blind ultraviolet detector with a peak responsivity of 1.42 A/W at 10 V was achieved,being 50 times higher than that of the nonpolarization-enhanced one.Moreover,an electron reservoir structure was proposed to further improve the performance.A higher peak responsivity of 3.1 A/W at30 V was achieved because the electron reservoir structure could modulate the electron concentration in the conduction channel.The investigation presented here provided feasible approaches to improve the performance of the AlGaN detector by taking advantage of its inherent property. | Ke Jiang Xiaojuan Sun Zi-Hui Zhang Jianwei Ben Jiamang Che Zhiming Shi Yuping Jia Yang Chen Shanli Zhang Wei Lv Dabing Li | 2020 | Photonics Research2020，8，7： | 3 |
| 15 | Genome-wide analysis of the barley non-specific lipid transfer protein gene family显示文摘Non-specific lipid transfer proteins(nsLTPs) are small, basic proteins that are characterized by an eight-cysteine motif. The biological functions of these proteins have been reported to involve plant reproduction and biotic or abiotic stress response. With the completion of the barley genome sequence, a genome-wide analysis of nsLTPs in barley(Hordeum vulgare L.)(HvLTPs) will be helpful for understanding the function of nsLTPs in plants. We performed a genome-wide analysis of the nsLTP gene family in barley and identified 70 nsLTP genes,which can be divided into five types(1, 2, C, D, and G). Each type of nsLTPs shares similar exon and intron gene structures. Expression analysis showed that barley nsLTPs have diverse expression patterns, revealing their various roles. Our results shed light on the phylogenetic relationships and potential functions of barley nsLTPs and will be useful for future studies of barley development and molecular breeding. | Mengyue Zhang Yujin Kim Jie Zong Hong Lin Anne Dievart Huanjun Li Dabing Zhang Wanqi Liang | 2019 | The Crop Journal2019，7，1： | 2 |
| 16 | Boosting the kinetics of PF_(6)^(-) into graphitic layers for the optimal cathode of dual-ion batteries:The rehearsal of pre-intercalating Li^(+)显示文摘Large anions exhibit slow diffusion kinetics in graphite cathode of dual-ion batteries(DIBs);particularly at high current density,it suffers severely from the largely-reduced interlayer utilization of graphite cathode,which as a bottleneck limits the fast charge application of DIBs.To maximize interlayer utilization and achieve faster anion diffusion kinetics,a fast and uncrowded anion transport channel must be established.Herein,Li^(+)was pre-intercalated into the graphite paper(GP)cathode to increase the interlayer spacing,and then hosted for the PF_(6)^(-)anion storage.Combined with theoretical calculation,it shows that the local interlayer spacing enlargement and the residual Li^(+)reduce the anion intercalation energy and diffusion barrier,leading to better rate stability.The obtained GP with Li^(+)pre-intercalation(GP-Li)electrode exhibits a discharge capacity of 23.1 m Ah g^(-1) at a high current of 1300 m A g^(-1).This work provides a facile method to efficiently improve the interlayer utilization of graphite cathode at large currents. | He Yang Tingting Qin Xinyan Zhou Yu Feng Zizhun Wang Xin Ge Nailin Yue Dabing Li Wei Zhang Weitao Zheng | 2022 | Journal of Energy Chemistry2022，31，8： | 2 |
| 17 | Prevalence of HIV and Syphilis Infection among Men Who Have Sex with Men in China: A Meta-Analysis显示文摘 | Yunhua Zhou Dongliang Li Dabing Lu Yuhua Ruan Xiao Qi Ge Gao Muktar Aliyu | 2014 | BioMed Research International2014，，： | 2 |
| 18 | Switching Optimally Balanced Fe-N Interaction Enables Extremely Stable Energy Storage显示文摘The interaction between electrode materials and charge carriers is one of the central issues dominating underlying energy storage mechanisms.To address the notoriously significant volume changes accompanying intercalation or formation of alloy/compounds,we aim to introduce and utilize a weak,reversible Fe-N interaction during the(de)intercalation of ammonium ions(NH_(4)^(+))within iron(Ⅲ)hexacyanoferrate(FeHCF),inspired by manipulating the electrostatic adsorption between N and Fe in the early stages of ammonia synthesis(Bosch-Harber Process,Chemical Engineering)and steel nitriding processes(Metal Industry).Such strategy of switching well-balanced Fe-N interaction is confirmed in between the nitrogen of ammonium ions and highspin Fe in FeHCF,as observed by using X-ray absorption spectroscopy.The resulting material provided an extremely stable energy storage(58 mAh g^(-1) after 10000 cycles at current density of 1 A g^(-1))as well as high-rate performance(23.6 mAh g^(-1) at current density of 10 A g^(-1)). | Zhenzhen Zhao Wei Zhang Miao Liu Dong Wang Xiyang Wang Lirong Zheng Xu Zou Zizhun Wang Dabing Li Keke Huang Weitao Zheng | 2023 | Energy & Environmental Materials2023，6，2： | 1 |
| 19 | Development and evaluation of a VP3-ELISA for the detection of goose and Muscovy duck parvovirus antibodies显示文摘 | Yun Zhang Yongfeng Li Ming Liu Dabing Zhang Dongchun Guo Chunguo Liu Haidong Zhi Xiaomei Wang Gang Li Na Li Shiguo Liu Wenhua Xiang Guangzhi Tong | 2009 | Journal of Virological Methods2009，，2： | 1 |
| 20 | Effect of buffer layer annealing temperature on the crystalline quality of In 0.82 Ga 0.18 As layers grown by two-step growth method显示文摘 | Xia Liu Hang Song Guoqing Miao Hong Jiang Lianzhen Cao Dabing Li Xiaojuan Sun Yiren Chen Zhiming Li | 2011 | Journal of Alloys and Compounds2011，，24： | 1 |
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