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| 1 | 柑橘木虱对柑橘不同品种的趋性显示文摘用2种方法测定了柑橘木虱Diaphorina citri Kuw.成虫对13个柑橘品种离体嫩梢的选择性。结果表明,对不同品种进行两两组合的选择性试验,柑橘木虱停靠在处理组合早金和四季斑叶橘的虫量占总虫量的23%和1%,停靠在处理组合台湾玫瑰橙和纽荷尔脐橙上的虫量分别占总虫量的33%和20%,停靠在处理组合日辉和佩奇甜橙上虫量分别占总虫量的38%和15%,两两之间差异显著。将13个品种组合在一起进行选择性试验,结果表明柑橘木虱停靠在纽荷尔、福橘和佩奇甜橙上的成虫数量为每梢3.2-6.6只.d-1,显著高于木虱在其余10个品种枝梢上的停靠数量。福橘是柑橘黄龙病高发品种的原因是其对柑橘木虱的吸引力较强。 | 陈建利 阮传清 刘波 范国成 段永平 D.HALL | 2011 | 福建农业学报2011,26,2: | 6 |
| 2 | The Soft X-ray Imager(SXI)on the SMILE Mission显示文摘The Soft X-ray Imager(SXI)is part of the scientific payload of the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission.SMILE is a joint science mission between the European Space Agency(ESA)and the Chinese Academy of Sciences(CAS)and is due for launch in 2025.SXI is a compact X-ray telescope with a wide field-of-view(FOV)capable of encompassing large portions of Earth’s magnetosphere from the vantage point of the SMILE orbit.SXI is sensitive to the soft X-rays produced by the Solar Wind Charge eXchange(SWCX)process produced when heavy ions of solar wind origin interact with neutral particles in Earth’s exosphere.SWCX provides a mechanism for boundary detection within the magnetosphere,such as the position of Earth’s magnetopause,because the solar wind heavy ions have a very low density in regions of closed magnetic field lines.The sensitivity of the SXI is such that it can potentially track movements of the magnetopause on timescales of a few minutes and the orbit of SMILE will enable such movements to be tracked for segments lasting many hours.SXI is led by the University of Leicester in the United Kingdom(UK)with collaborating organisations on hardware,software and science support within the UK,Europe,China and the United States. | S.Sembay A.L.Alme D.Agnolon T.Arnold A.Beardmore A.Belén Balado Margeli C.Bicknell C.Bouldin G.Branduardi-Raymont T.Crawford J.P.Breuer T.Buggey G.Butcher R.Canchal J.A.Carter A.Cheney Y.Collado-Vega H.Connor T.Crawford N.Eaton C.Feldman C.Forsyth T.Frantzen G.Galgóczi J.Garcia G.Y.Genov C.Gordillo H-P.Gröbelbauer M.Guedel Y.Guo M.Hailey D.Hall R.Hampson J.Hasiba O.Hetherington A.Holland S-Y.Hsieh M.W.J.Hubbard H.Jeszenszky M.Jones T.Kennedy K.Koch-Mehrin S.Kögl S.Krucker K.D.Kuntz C.Lakin G.Laky O.Lylund A.Martindale J.Miguel Mas Hesse R.Nakamura K.Oksavik N.Østgaard H.Ottacher R.Ottensamer C.Pagani S.Parsons P.Patel J.Pearson G.Peikert F.S.Porter T.Pouliantis B.H.Qureshi W.Raab G.Randal A.M.Read N.M.M.Roque M.E.Rostad C.Runciman S.Sachdev A.Samsonov M.Soman D.Sibeck S.Smit J.Søndergaard R.Speight S.Stavland M.Steller TianRan Sun J.Thornhill W.Thomas K.Ullaland B.Walsh D.Walton C.Wang S.Yang | 2024 | Earth and Planetary Physics2024,8,1: | 4 |
| 3 | 洋地黄类与其他药物的相互作用显示文摘心力衰竭(心衰)患者在应用洋地黄制剂的同时,常需加用其他药物,以达到控制心衰或治疗伴随疾病的目的。此间存在药物的相互作用问题。由于洋地黄类药物的治疗安全范围甚小,即有效血浓与中毒血浓水平差别不大,加上心衰患者本身耐受性差,易于发生中毒,而中毒症象有时难以识别;且在药浓度变化不大,甚至药浓不变而存在电解质失常或其他附加因素时也可导致严重反应。因而要求医师时常保持警惕,并掌握有关洋地黄类药物与其它药物的相互作用的知识。 | D.Hall F.Kraus W.Rudolph 曾昭耆 | 1994 | 德国医学1994,11,1: | 3 |
| 4 | Clinical laboratory and imaging evidence for effectiveness of agarose-agarose macrobeads containing stem-like cells derived from a mouse renal adenocarcinoma cell population (RMBs) in treatment-resistant, advanced metastatic colorectal cancer:Evaluation of显示文摘Objective: The complexity, heterogeneity and capacity of malignant neoplastic cells and tumors for rapid change and evolution suggest that living-cell-based biological-systems approaches to cancer treatment are merited. Testing this hypothesis, the tumor marker, metabolic activity, and overall survival(OS) responses, to the use of one such system, implantable macrobeads [RENCA macrobeads(RMBs)], in phase I and IIa clinical trials in advanced,treatment-resistant metastatic colorectal cancer(m CRC) are described here.Methods: Forty-eight m CRC patients(30 females; 18 males), who had failed all available, approved treatments,underwent RMB implantation(8 RMB/kg body weight) up to 4 times in phase I and phase IIa open-label trials.Physicals, labs [tumor and inflammation markers, lactate dehydrogenase(LDH)] and positron emission tomography-computed tomography(PET-CT) imaging to measure number/volume and metabolic activity of the tumors were performed pre-and 3-month-post-implantation to evaluate safety and initial efficacy(as defined by biological responses). PET-CT maximum standard uptake value(SUVmax)(baseline and d 90; SUVmax ≥2.5), LDH,and carcinoembryonic antigen(CEA) and/or cancer antigen 19-9(CA 19-9) response(baseline, d 30 and/or d 60)were assessed and compared to OS.Results: Responses after implantation were characterized by an at least 20% decrease in CEA and/or CA 19-9 in75% of patients. Fluorodeoxyglucose(FDG)-positive lesions(phase I, 39; 2 a, 82) were detected in 37/48 evaluable patients, with 35% stable volume and stable or decreased SUV(10) plus four with necrosis; 10, increased tumor volume, SUV. LDH levels remained stable and low in Responders(R)(d 0–60, 290.4–333.9), but increased steadily in Non-responders(NR)(d 0–60, 382.8–1,278.5)(d 60, P=0.050). Responders to RMBs, indicated by the changes in the above markers, correlated with OS(R mean OS=10.76 months; NR mean OS=4.9 months; P=0.0006).Conclusions: The correlations of the tumor marker, tumor volume and SUV changes on PET-CT, and LDH levels themselves, and with OS, support the concept of a biological response to RMB implantation and the validity of the biological-systems approach to m CRC. A phase III clinical trial is planned. | Barry H.Smith Lawrence S.Gazda Thomas J.Fahey Angelica Nazarian Melissa A.Laramore Prithy Martis Zoe P.Andrada Joanne Thomas Tapan Parikh Sudipta Sureshbabu Nathaniel Berman Allyson J.Ocean Richard D.Hall David J.Wolf | 2018 | Chinese Journal of Cancer Research2018,30,1: | 2 |
| 5 | The double helium-white dwarf channel for the formation of AM CVn binaries显示文摘Most close double helium white dwarfs will merge within a Hubble time due to orbital decay by gravitational wave radiation.However,a significant fraction with low mass ratios will survive for a long time as a consequence of stable mass transfer.Such stable mass transfer between two helium white dwarfs(He WDs) provides one channel for the production of AM CVn binary stars.In previous calculations of double He WD progenitors,the accreting He WD was treated as a point mass.We have computed the evolution of 16 double He WD models in order to investigate the consequences of treating the evolution of both components in detail.We find that the boundary between binaries having stable and unstable mass transfer is slightly modified by this approach.By comparing with observed periods and mass ratios,we redetermine masses of eight known AM CVn stars by our double He WDs channel,i.e.HM Cnc,AM CVn,V406 Hya,J0926,J1240,GP Com,Gaia14 aae and V396 Hya.We propose that central spikes in the triple-peaked emission spectra of J1240,GP Com and V396 Hya and the surface abundance ratios of N/C/O in GP Com can be explained by the stable double He WD channel.The mass estimates derived from our calculations are used to discuss the predicted gravitational wave signal in the context of the Laser Interferometer Space Antenna(LISA) project. | Xian-Fei Zhang Jin-Zhong Liu C.Simon Jeffery Philip D.Hall Shao-Lan Bi | 2018 | Research in Astronomy and Astrophysics2018,18,1: | 2 |
| 6 | A Ca^(2+) cycling defect connects insulin resistance and heart failure显示文摘In a recent study published in Life Metabolism,Quan et al.reported that intracellular Ca^(2+)dysregulation in cardiomyocyte can be both a cause and an effect of cardiac insulin resistance that ultimately leads to diabetic cardiomyopathy.Numerous epidemiologic studies across several decades indicate that insulin-resistant states such as diabetes and obesity are risk factors for congestive heart failure independent of common cardiovascular disease factors such as hypertension and coronary artery diseases[1,2].On the other hand,there is evidence that heart failure itself causes the onset and development of insulin resistance[3].Restoring normal cardiac output in advanced heart failure patients with left ventricular assistance devices improves insulin sensitivity and cardiac metabolism[4]. | Qian Shi Duane D.Hall Long-Sheng Song | 2022 | Life Metabolism2022,1,1: | 0 |
| 7 | Chowing down:diet considerations in rodent models of metabolic disease显示文摘Diet plays a substantial role in the etiology, progression, and treatment of chronic disease and is best considered as a multifacetedset of modifiable input variables with pleiotropic effects on a variety of biological pathways spanning multiple organ systems. Thisbrief review discusses key issues related to the design and conduct of diet interventions in rodent models of metabolic disease andtheir implications for interpreting experiments. We also make specific recommendations to improve rodent diet studies to help betterunderstand the role of diet on metabolic physiology and thereby improve our understanding of metabolic disease. | Kevin C.Klatt Kevin Bass John R.Speakman Kevin D.Hall | 2023 | Life Metabolism2023,2,3: | 0 |