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| 1 | 非小细胞肺癌术后三维适形放疗与常规放疗的疗效比较显示文摘背景与目的:非小细胞肺癌术后三维适形放疗与常规放疗的疗效比较目前尚缺乏长期随访结果.本研究回顾性分析非小细胞肺癌(NSCLC)术后分别采用三维适形放疗和常规放疗的疗效及放疗反应,比较不同放疗技术对疗效及放疗反应的影响。方法:收集1990年12月-2002年8月美国M.D.安德森癌症研究中心收治的167例Ⅲ.期NSCLC患者的术后放疗资料进行回顾性分析。其中常规放疗组(CV组)90例.三维适形放疗组(CF组)77例。CV组放疗中位剂量为54.3Gy/27次.CF组放疗中位刹龟为53.9Gy/26次.均在5~6周内完成。结果:两组患者病例特征具有可比性。CV组和CF组中位随访时间分别为36个月和24个月,两组无瘤生存率、局部控制率及无远处转移生存率差异无显著性,但两组总生存率差异有显著性(P=0.014)。CF组在肺部纤维化、心脏损伤和血液系统放疔反应发生率显著性上要低于CV组,其余放疗反应差异基本尤最著性。两组死亡原因差异有显著性,CV组有8例患者死于与心脏损伤有关的并发症,而CF组没有。结论:Ⅲ、期NSCLC术后采用改进的三维适形放疗技术不仅可以取得与常规放疗类似的疗效,还可提高总生存率,同时降低了肺部纤维化、心脏损伤和血液系统反应发生率,三维适形放疗的治疗优势值得关注. | 林原 Zhongxing Liao Pamela K.Allen James D.Cox Ritsuko Komaki | 2007 | 中国癌症杂志2007，17，4： | 4 |
| 2 | Institutional considerations in developing a faculty learning community program显示文摘 | Gary M.Shulman Milton D.Cox LaurieRichlin | 2004 | New Directions for Teaching and Learning2004，，97： | 1 |
| 3 | Persistent disparities in liver transplantation for patients with hepatocellular carcinoma in the United States, 1998 through 2007显示文摘 | Anthony S.Robbins Derrick D.Cox Lynt B.Johnson Elizabeth M.Ward | 2011 | Cancer2011，，19： | 1 |
| 4 | Treatment of unicentric and multicentric Castleman disease and the role of radiotherapy显示文摘 | Gregory M.Chronowski Chul S.Ha Richard B.Wilder FernandoCabanillas JohnManning James D.Cox | 2001 | Cancer2001，，3： | 1 |
| 5 | Treatment of unicentric and multicentric Castleman disease and the role of radiotherapy显示文摘 | Gregory M.Chronowski Chul S.Ha Richard B.Wilder FernandoCabanillas JohnManning James D.Cox | 2001 | Cancer2001，，3： | 1 |
| 6 | Mutation in the LPS outer core biosynthesis gene, galU, affects LPS interaction with the RTX toxins ApxI and ApxII and cytolytic activity of Actinobacillus pleuropneumoniae serotype 1显示文摘 | MahendrasinghRamjeet Andrew D.Cox Mark A.Hancock MichaelMourez JoséeLabrie MarceloGottschalk MarioJacques | 2008 | Molecular Microbiology2008，，1： | 1 |
| 7 | Coping in a Global Marketplace:Survival Strategies for a 75-Year-Old SEC显示文摘 | James D.Cox | | 0，，04： | 1 |
| 8 | Behavioral evidence for contextual olfactory-mediated avoidance of the ubiquitous phytopathogen Botrytis cinerea by Drosophila suzukii显示文摘Herbivorous insects may benefit from avoiding the smell produced by phytopathogens infecting plant host tissue if the infected tissue reduces insect fitness.However,in many cases the same species of phytopathogen can also infect host plant tissues that do not directly affect herbivore fitness.Thus,insects may benefit from differentiating between pathogen odors emanating from food and nonfood tissues.This is based on the hypothesis that unecessarily staying attentive to pathogen odor from nonfood tissue may incur opportunity costs associated with not responding to other important survival functions.In this study adults of Drosophila suzukii Matsumura,an invasive larval frugivore,showed reduced attraction to the odor of raspberry fruit,a food tissue,when infected with Botrytis cinerea Pers.,a ubiquitous phytopathogen,in favor of odors of uninfected raspberry fruit.Moreover,D.suzukii oviposited fewer eggs on infected raspberry fruit relative to uninfected raspberry fruit.Larval survival and adult size after eclosion were significantly reduced when reared on B.cinerea-infected raspberry relative to uninfected fruit.Interestingly,when the behavioral choice experiment was repeated using Botrytis-infected vsuninfected strawberry leaves,a nonfood tissue,in combination with fresh raspberry fruit,odor from B.cinerea-infected leaves did not reduce D.suzukii attraction to raspberries rel-ative to raspberries with uninfected leaves.These behavioral results illustrate the important role context can play in odor-mediated interactions between insects,plants and microbes.We discuss implications of our findings for developing a repellent that can be useful for the management of D.suzukii. | Dong H.Cha Stephen P.Hesler Gabrielle Brind'Amour Karen S.Wentworth Sara Villani Kerik D.Cox Matthew T.Boucher Anna Wallingford Shinyoung K.Park Jan Nyrop Gregory M.Loeb | 2020 | Insect Science2020，27，4： | 0 |
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