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13篇 您的检索式:作者名="Cuix"
    题名 作者 年代 出处 被引量
1定量分析乳腺癌术后化疗前外周血多药耐药基因的检测及其临床意义的研究(英文)显示文摘Objective: To explore expressions of multidrug resistance gene (MDR) product P170 and peripheral blood MDR1 mRNA in breast cancer tissue and their clinical significances. Methods: Fluorescent quantitative RT-PCR and immunohis-tochemistry were used to detect peripheral blood MDR1 mRNA before chemotherapy in breast cancer tissue samples from 32 cases with P170 positive (trial group) and 11 cases with P170 negative (control group). Results: There were 14 cases (43.75%) peripheral blood MDR1 mRNA positive and 18 cases (56.25%) negative in 32 cases P170 positive breast cancer pa-tients, while there were 6 cases (54.55%) peripheral blood MDR1 mRNA positive and 5 cases (45.45%) negative in 11 cases P170 negative breast cancer patients; there wasn't a significance difference with peripheral blood MDR1 mRNA express rate in P170 positive (43.75%) group and P170 negative (54.55%) group (χ2 = 0.383, P > 0.05). There were 12 cases (37.50%) Her-2 positive and 20 cases (62.50%) negative in P170 positive group; there were 2 cases (18.18%) Her-2 positive and 9 cases (81.82%) negative in P170 negative group; there wasn't a significance difference with Her-2 positive rate in P170 posi-tive group (37.50%) and P170 negative (18.18%) group (χ2 = 1.391, P > 0.05). There were 13 cases (40.63%) ER positive and 19 cases (59.37%) negative in P170 positive group; there were 7 cases (63.64%) ER positive and 4 cases (36.36%) negative in P170 negative group; there wasn't a significance difference with ER positive rate in P170 positive group (40.63%) and P170 negative (63.64) group (χ2 = 1.742, P > 0.05). There were 20 cases (62.50%) PR positive and 12 cases (37.50%) negative in P170 positive group; there were 4 cases (36.36%) PR positive and 7 cases (63.64%) negative in P170 negative group; there wasn't a significance difference with PR positive rate in P170 positive group (62.50%) and P170 negative (36.36%) group (χ2 = 2.267, P > 0.05). There were 9 cases (28.12%) with lymphaden metastasis and 23 cases (71.88%) without lymphaden metastasis in P170 positive group; there were 5 cases (45.45%) with lymphaden metastasis and 6 cases (54.55%) without lymphaden metastasis in P170 negative group; there wasn't a significance difference with lymphaden metastasis rate in P170 positive group (28.12%) and P170 negative (45.45%) group (χ2 = 1.120, P > 0.05). Conclusion: 1) There were possibly MDR expressing infrequently in carcinoma tissue and peripheral blood before chemotherapy. 2) FQ-RT-PCR for detecting of periph-eral blood MDR1 mRNA is special, sensitive and reliable. It can be used as new molecular biology diagnostic maker dynamic detecting peripheral blood MDR1 mRNA for regulating chemotherapy proposal and elevating chemotherapy effect.Xinmei Wang Liang Li Qjng Cuix Muxin Wang Yu Ding Tongfu Jia Jianzhao Li Ningning Feng Anjing Zuo Yanchang Feng 2008The Chinese-German Journal of Clinical Oncology2008,7,11:2
2A Marek's disease virus vIL-8 deletion mutant has attenuated virulence and confers protection against challenge with a very virulent plus strain 显示文摘CUIX LEE L F HUNT H D 2005Avain Dis2005,49,9:1
3Oxidative stress in the placenta显示文摘Myatt L Cuix 2004Histochem Cell Biol2004,122,4:1
4Annealing control primer system identifies differentially expressed genes in blastocyst-stage porcine parthenotes显示文摘LEEHY CUIX S LEE K A 2006Zygote2006,14,1:1
5显示文摘申刚义(ShenGY) 于婷婷(YuWT) 刘美蓉(LiuMR) 崔勋(CuiX) 2013化学进展2013,25,:1
6Clinical analysis of 12 cases of HFMD with encephalitis an dmeningitis显示文摘Fang YH Cuix M 2009Chin Gen Med2009,9,3:1
7Rice MADS3 regulates ROS homeostasis during late anther development 显示文摘HuLF LiangWQ YinCS CuiX ZongJ WangX Hu J Zhang D 2011The Plant Cell2011,23,2:1
8Oxidative stress in the placenta显示文摘Myatt L Cuix 2004Histochem Cell Biol2004,122,4:1
9In vitro expansion of a multipotent population of human neural progenitor cells 显示文摘Carpenter MK CuiX Hu ZY 1999Exp Neurol1999,158,2:1
10In vitro expansion of a mul tipotent population of human neural progenitor cells显示文摘Carpenter MK CuiX Hu ZY etal 1999Exp Neuroi1999,158,2:1
11Actinstabilizationbyjasplakinolideaffectsthefunctionofbone marrow-de-rivedlateendothelialprogenitorcells显示文摘ZhangX CuiX ChengL etal 2012PLoS One2012,7,11:1
12Elevated expression of hepcidin post-renal ischemia reperfusion injury显示文摘Cuixing Zhou Xiaozhou He Dong Xue Nin Xu 2013Acta Biochimica et Biophysica Sinica2013,45,4:0
13Prognostic Role of nm23 and ras-P21 Expression in Gastric Carcinoma显示文摘Expression and prognostic impact of nm23 and ras-p21 were immunohistochemically studied in 60 resected gastric carcinomas. Tumor sections of the 60 gastric carcinomas were stained with monoclonal antibodies that were raised against the nm23-H1/NDP kinase A, and ras-p21. Expression of both nm23 and ras-p21 was positively correlated with macroscopic type and ras-p21 was correlated the histologic type. In contrast,ZhaoPeng CuiXing SakaguchiTakeo LiuLi-li ZhangQi-fan HatakeyamaKatsuyoshi 2000胃肠病学2000,5,B08:0
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