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| 1 | FGF-2/FGFR信号转导途径与肿瘤的关系及在乳腺癌发生中的作用显示文摘碱性成纤维细胞生长因子(FGF-2)是一种能调节细胞分裂、增殖、迁移及分化的多效生长因子。研究表明,FGF-2在肿瘤生长和新血管生成中起重要的作用。FGF-2诱导的生物学效应很大程度上是依赖于TPK受体(酪氨酸激酶受体)和胞内二级信使分子(mitogen activted protein kinase)等蛋白分子组成的功能性信号转导网络来实现的,该网络中不同信号转导通路的活化状态对应着各种不同的生物学效应。本文将阐述在肿瘤及乳腺癌发生过程中FGF-2诱导的信号转导途径的作用机理方面的研究进展。 | 方剑武 黄思罗 Michel Crepin 刘会生 徐涛 刘剑峰 | 2003 | 科学通报2003，48，13： | 4 |
| 2 | Tumor growth inhibition, apoptosis, and Bel-2 down-regulation of MCF-7ras tumors by sodium phenylacetate and tamoxifen combination 显示文摘 | Adam L Crepin M Israel L | 1997 | Cancer Res1997，57，6： | 1 |
| 3 | Proteomic detection of changes in protein synthesis induced by fibroblast growth factor-2 in MCF-7 human breast cancer cells显示文摘 | VERCOUTTER-EDOUART A S CZESZAK X CREPIN M | 2001 | Exp Cell Res2001，262，1： | 1 |
| 4 | FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway 显示文摘 | Liu JF Crepin M Liu JM | 2002 | Biochem Biophys Res Commun2002，293，4： | 1 |
| 5 | Bel -2 -dependentmodulation of swelling -activated Cl' current and C1C -3expression in human prostate cancer epithelial cells 显示文摘 | Lemonnier L Shuba Y Crepin A | 2004 | Cancer Res2004，64，14： | 1 |
| 6 | Enteropathogenic and enterohemorrhagic Escherichia coli infections: translocation, tran- slocation, translocation显示文摘 | Garmendia J Frankel G Crepin VF | 2005 | Infect Irnmun2005，73，5： | 1 |
| 7 | Production and characterization of the Talaromyces stipitatus feruloyl esterase FAEC in Pichia pastoris:identification of the nucleophilic serine显示文摘 | Crepin V F Faulds C B Connerton I F | 2003 | Protein Expression and Purification2003，，29： | 1 |
| 8 | Structural and functional studies of the enteropathogenic Escherichia coli type Ⅲ needle complex protein EscJ显示文摘 | Crepin VF Prasannan S Shaw RK | 2005 | Mol Microbiol2005，55，： | 1 |
| 9 | On the Conversion of High-Frequency Soliton Solutions to a (1+1)-Dimensional Nonlinear Partial Differential Evolution Equation显示文摘从在压力不安下面放松媒介的 barotropic 的动态方程,并且用减少的 perturbative 分析,我们调查 soliton 结构一( 1+1 )维的非线性的部分微分进化( NLPDE )方程部分衍生物(y)(部分衍生物(希腊语字母的第七字)+ u 部分衍生物(y)+( u ( 2 ) /2 )部分衍生物(y)) u +高山哈 u (y)+ u = 0 ,描述不安的高周波的政体。借助于 Hirota 的 bilinearization 方法,因此,强烈取决于一个典型驱散参数的三个典型答案被发掘。 | Kuetche Kamgang Victor Bouetou Bouetou Thomas Timoleon Crepin Kofane | 2008 | Chinese Physics Letters2008，25，6： | 1 |
| 10 | The feasibility of vaginal hysterectomy显示文摘 | Michel Cosson Denis Querleu Damien Subtil Isabelle Switala Benedicte Buchet Gilles Crepin | 1996 | European Journal of Obstetrics and Gynecology1996，，1： | 1 |
| 11 | Proteomic detection of changes in protein synthesis induced by fibroblast growth factor- 2 in MCF- 7 human breast cancer cells显示文摘 | Vereoutter- Edouart AS Czeszak X Crepin M | 2001 | Exp Cell Res2001，262，1： | 1 |
| 12 | Enteropathogenic and Enterohemorrhagic Escherichia coli Infections: Translocation, Translocation, Translocation显示文摘 | Garmendia J Frankel G Crepin VF | 2005 | Infect Immun2005，73，5： | 1 |
| 13 | Bcl-2- dependent modulation of swelling-activated Cl-current and ClC-3 expression in human prostate cancer epithelial cells显示文摘 | Lemonnier L Shuba Y Crepin A | 2004 | Cancer Res2004，64，： | 1 |
| 14 | Functional classification of the microbial feruloyl esterases 显示文摘 | Crepin VF Faulds CB Connerton IF | 2004 | Applied Microbiology and Biotechnology2004，63，： | 1 |
| 15 | Herpes simplex virus type 1 latently infected neurons differentially express latency-associated and ICP0 transcripts显示文摘 | Maillet S Naas T Crepin S | | 0，，18： | 1 |
| 16 | The feasibility of vaginal hysterectomy显示文摘 | Michel Cosson Denis Querleu Damien Subtil Isabelle Switala Benedicte Buchet Gilles Crepin | 1996 | European Journal of Obstetrics and Gynecology1996，，1： | 1 |
| 17 | Intravitam diagnosis of human rabies by PCR using saliva and cerebrospinal fluid显示文摘 | Crepin P Audry L Rotivel Y | 1998 | J Clin Microbiol1998，36，： | 1 |
| 18 | Intravitam diagnosis of human rabies by PCR using saliva and eerebrospinal fluid 显示文摘 | Crepin P Audry L Rotivel Y | 1998 | J Clin Mierobiol1998，36，4： | 1 |
| 19 | Subversion of actin dynamics by EPEC and EHEC显示文摘 | Caron E Crepin V F Simpson N | 2006 | Curr Opin Microbiol2006，9，1： | 1 |
| 20 | Evidence for different hu-man tracheobronchial mucin peptides deduced from nucleotide cD-NA sequences显示文摘 | Aubert JP Porchet N Crepin M | 1991 | Am J Respir Cell Mol Biol1991，5，2： | 1 |
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