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| 1 | Home bias, foreign mutual fund holdings, and the voluntary adoption of international accounting standards显示文摘 | Covrig V M Defond M L Hung M | 2007 | Journal of Accounting Research2007，45，1： | 1 |
| 2 | Asymmetric information and price discovery in the FX Market: dose Tokyo know more about the yen? 显示文摘 | Vicentiu Covrig Michael Melvin | 2002 | Journal of Empirical Finance2002，，8： | 1 |
| 3 | The contribution of a satellite market to price discovery: Evidence from the Singapore exchange显示文摘 | Covrig V Ding D Low B S | 2004 | Journal of Futures Markets2004，24，10： | 1 |
| 4 | The Relevance of Analysts' Earnings Forecasts in Japan显示文摘 | Covrig V B.S.Low | | 0，，7： | 1 |
| 5 | Home bias,foreign mutual fund holdings,and the voluntary adoption of International Accounting Standards显示文摘 | Covrig V DeFond M Hung M | | 0，，01： | 1 |
| 6 | Home Bias,Foreign Mutual Fund Holdings,and the Voluntary Adoption of International Accounting Standards显示文摘 | Covrig V M.DeFond M.Hung | | 0，，： | 1 |
| 7 | Home Bias, Foreign Mutual Fund Holdings, and the Voluntary Adoption of International Accounting Standards 显示文摘 | Covrig V Defond M Hung M Y | 2007 | Journal of Accounting Research2007，45，1： | 1 |
| 8 | Home bias, foreign mutual fund holdings, and the voluntary adoption of in-ternational accounting standards显示文摘 | Covrig V DeFond M Hung M | | 0，，01： | 1 |
| 9 | The Contribution of a Satellite Market to Price Discovery : Evidence from the Singapore Ex- change显示文摘 | Covrig V Ding D Low B - S | 2004 | Journal of Futures Markets2004，，24： | 1 |
| 10 | The Contribution of a Satellite Market to Price Discovery:Evidence from the Singapore Exchange显示文摘 | Vicentiu Covrig David K.Ding Buen Sin Low | | 0，，10： | 1 |
| 11 | Efficiency increase for e lectrical fire detection and alarm systems through implementa tion of fuzzy expert systems显示文摘 | Homeag I Parlog-Cristian R Covrig M | 2013 | Electrical Engineering2013，75，1： | 1 |
| 12 | Numerical a- nalysis of a PM synchronous motor used in electrical vehicles 显示文摘 | Uncuta S Melcescu L Covrig M | 2011 | International Symposium on Advanced Topics in Electrical Engineering2011，，： | 1 |
| 13 | What determines the domestic bias and foreign bias? Evidence from mutual fund equity allocations worldwide显示文摘 | Kalok Chan Vicentiu Covrig Lilian NG | 2005 | The journal of finance2005，60，3： | 1 |
| 14 | The contribution of a satellite market to price discovery: Evidence from the Singapore exchange 显示文摘 | Covrig V Ding D Low B | 2004 | Journal of Futures Markets2004，24，10： | 1 |
| 15 | Home Bias, Foreign Mutual Fund Holdings, and the Voluntary Adoption of International Accounting Standards显示文摘 | Vicentium Covrig Markl Defond Ming Yi hung | 2007 | Journal of Accounting Research2007，45，： | 1 |
| 16 | Home Bias, Foreign Mutual Fund Holdings, and the Voluntray Adoption of International Accounting Standards 显示文摘 | Covrig V M Defond and M Hung | 2007 | Journal of Accounting Research2007，45，1： | 1 |
| 17 | Oxaliplatin-induced neuropathy and colo-rectal cancer patient's quality of life:Practical lessons from a prospective cross-sectional,real-world study显示文摘BACKGROUND Colon cancer is one the most common forms of cancer in both sexes.Due to important progress in the field of early detection and effective treatment,colon and rectal cancer survivors currently account for 10%of cancer survivors worldwide.However,the effects of anti-cancer treatments,especially oxaliplatinbased chemotherapy,on the quality of life(QoL)have been less evaluated.Although the incidence of severe chemotherapy-induced neuropathy(CIPN)in clinical studies is below 20%,data from real-world studies is scarce,and CIPN is probably under-reported due to patient selection and the patients’fear that reporting side-effects might lead to treatment cessation.AIM To determine the impact of CIPN on QoL in colorectal cancer patients with a recent history of oxaliplatin-based chemotherapy.METHODS We performed a prospective cross-sectional study in two major Romanian oncology tertiary hospitals—the Regional Institute of Oncology Ia?i(Iasi,Romania)and the Fundeni Clinical Oncology Institute(Bucharest,Romania).All consecutive patients with colon or rectal cancer,undergoing Oxaliplatin-based chemotherapy that consented to enroll in the study,were assessed by means of two questionnaires—the EORTC QQ-CR29(quality of life in colon and rectal cancer patients)and the QLQ-CIPN20(assessment of neuropathy).Several demographical,social,clinical and treatment data were also collected.Statistical analysis was performed by means of SPSS v20.The student t test was used to assess the relationship between the QLQ-CIPN20 and QLQ-CR29 results.Kaplan Meyer-curves were used to report 3-year progression-free survival(PFS)in patients that discontinued chemotherapy vs those that completed the recommended course.RESULTS Of the 267 patients that fulfilled the inclusion criteria in the pre-specified time frame,101(37.8%)agreed to participate in the clinical study.At the time of the enrolment in the study,over 50%of the patients had recently interrupted their oxaliplatin-based chemotherapy,most often due to neuropathy.Almost 85%of the responders reported having tingling or numbness in their fingers or hands,symptoms that were associated with pain in over 20%of the cases.When comparing the scores in the two questionnaires,a statistically significant relationship(P<0.001)was found between the presence of neuropathic symptoms and a decreased quality of life.This correlation was consistent when the patients were stratified by sex,disease stage,comorbidities and the presence of stoma or treatment type,suggesting that neuropathy in itself may be a reason for a decreased quality of life.At the 3 year final assessment,median recurrence-free survival in stageⅢpatients was 26.88 mo.When stratified by completion of chemotherapy,median recurrence freesurvival of stageⅢpatients that completed chemotherapy was 28.27 mo vs 24.33 mo in patients that discontinued chemotherapy due to toxicity,a difference that did not reach statistical significance.CONCLUSION CIPN significantly impacts QoL in colorectal cancer patients.CIPN is also the most frequent reason for treatment discontinuation.Physicians should actively assess for CIPN in order to prevent chronic neuropathy. | Iulian Prutianu Teodora Alexa-Stratulat Elena Octaviana Cristea Andrei Nicolau Diana Cornelia Moisuc Alina Alexandra Covrig Karina Ivanov Adina Emilia Croitoru Monica Ionela Miron Mihaela Ioana Dinu Anca Viorica Ivanov Mihai Vasile Marinca Iulian Radu Bogdan Gafton | 2022 | World Journal of Clinical Cases2022，10，10： | 0 |
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