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| 1 | Procalcitonin and intestinal ischemia:A review of the literature显示文摘Intestinal ischemia is common after emergency gastrointestinal or cardiovascular surgery.At present,there are no diagnostic tools for the early diagnosis of intestinal ischemia.In the last decade,procalcitonin(PCT)has been suggested as a marker of this condition.Here,we review the use of PCT as a diagnostic tool for intestinal ischemia.Two reviewers independently searched the Pub Med and EMBASE databases for articles on intestinal ischemia and PCT.They then considered(1)the criteria applicable to preclinical and clinicaldata;and(2)PCT’s predictive value in the diagnosis of intestinal ischemia.Article quality was rated according to the STAndards for Reporting of Diagnostic accuracy.Between 1993 and 2014,seven studies(including two preclinical studies and five clinical studies)dealt with the use of PCT to diagnose intestinal ischemia.Procalcitonin’s sensitivity,specificity,positive predictive value and negative predictive value ranged between 72%and 100%;68%and 91%;27%and 90%and 81%and 100%,respectively.The area under the receiver operating characteristic curve ranged from 0.77 to 0.92.In view of the preclinical and clinical data,we consider that PCT can be used in daily practice as a tool for diagnosing intestinal ischemia. | Cyril Cosse Charles Sabbagh Sad Kamel Antoine Galmiche Jean-Marc Regimbeau | 2014 | World Journal of Gastroenterology2014，20，47： | 9 |
| 2 | Response to endoscopic therapy for biliary anastomotic strictures in deceased versus living donor liver transplantation显示文摘BACKGROUND:Endoscopic therapy has been successful in the management of biliary complications after both deceased donor liver transplantation(DDLT) and living donor liver transplantation(LDLT).LDLT is thought to be associated with higher rates of biliary complications,but there are few studies comparing the success of endoscopic management of anastomotic strictures between the two groups.This study aims to compare our experience in the endoscopic management of anastomotic strictures in DDLT versus LDLT.METHODS:This is a retrospective database review of all liver transplant patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) after liver transplantation.The frequency of anastomotic stricture and the time to develop and to resolve anastomotic stricture were compared between DDLT and LDLT.The response of anastomotic stricture to endoscopic therapy was also analyzed.RESULTS:A total of 362 patients underwent liver transplantation between 2003 and 2011,with 125 requiring ERCP to manage biliary complications.Thirty-three(9.9%) cases of DDLT and 8(27.6%) of LDLT(P=0.01) were found to have anastomotic stricture.When comparing DDLT and LDLT,there was no difference in the mean time to the development of anastomotic strictures(98±17 vs 172±65 days,P=0.11),likelihood of response to ERCP [22(66.7%) vs 6(75.0%),P=0.69],mean time to the resolution of anastomotic strictures(268±77 vs 125±37 days,P=0.34),and the number of ERCPs required to achieve resolution(3.9±0.4 vs 4.7±0.9,P=0.38).CONCLUSIONS:Endoscopic therapy is effective in the majority of biliary complications relating to liver transplantation.Anastomotic strictures occur more frequently in LDLT compared with DDLT,with equivalent endoscopic treatment response and outcomes for both groups. | Calvin HY Chan Fergal Donnellan Michael F Byrne Alan Coss Mazhar Haque Holly Wiesenger Charles H Scudamore Urs P Steinbrecher Alan A Weiss Eric M Yoshida | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 7 |
| 3 | Frey procedure for the treatment of chronic pancreatitis associated with common bile duct stricture显示文摘BACKGROUND:The Frey procedure(FP)is the treatment of choice for symptomatic chronic pancreatitis(CP).In cases of biliary stricture,biliary derivation can be performed by choledochoduodenostomy,Roux-en-Y choledochojejunostomy or,more recently,reinsertion of the common bile duct(CBD)into the resection cavity.The objective of the present study was to evaluate the outcomes associated with each of these three types of biliary derivation.METHODS:We retrospectively analyzed demographic,CPrelated,surgical and follow-up data for patients having undergone FP for CP with biliary derivation between 2004and 2012 in our university medical center.The primary efficacy endpoint was the rate of CBD stricture recurrence.The secondary endpoints were surgical parameters,postoperative complications,postoperative follow-up and the presence of risk factors for secondary CBD stricture.RESULTS:Eighty patients underwent surgery for CP during the study period.Of these,15 patients received biliary derivation with the FP.Eight of the FPs(53.3%)were combined with choledochoduodenostomy,4(26.7%)with choledochojejunostomy and 3(20.0%)with reinsertion of the CBD into the resection cavity.The mean operating time was 390minutes.Eleven complications(73.3%)were recorded,including one major complication(6.7%)that necessitated radiologicallyguided drainage of an abdominal collection.The mean(range)length of stay was 17 days(8-28)and the median(range)follow-up time was 35.2 months(7.2-95.4).Two patients presented stricture after CBD reinsertion into the resection cavity;one was treated with radiologically-guided dilatation and the other underwent revisional Roux-en-Y choledochojejunostomy.Three patients presented alkaline reflux gastritis(37.5%),one(12.5%)cholangitis and one CBD stricture after FP with choledochoduodenostomy.No risk factors for secondary CBD stricture were identified.CONCLUSIONS:As part of a biliary derivation,the FP gave good results.We did not observe any complications specifically related to surgical treatment of the biliary tract.However,CBD reinsertion into the resection cavity appeared to be associated with a higher stricture recurrence rate.In our experience,choledochojejunostomy remains the'gold standard'for the surgical treatment for CBD strictures. | Lionel Rebibo Thierry Yzet Cyril Cosse Richard Delcenserie Eric Bartoli Jean-Marc Regimbeau | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，6： | 5 |
| 4 | 选择性雄激素受体调节剂治疗迟发性男性性腺功能低下症显示文摘几种睾酮制剂用于治疗老年男性性腺功能减退。这些疗法在其便利性、灵活性、区域供应和费用等方面有区别,但有共同的药代动力学基础,同时缺乏长期安全性数据。简洁和成本较低的基于药代动力学的注册临床试验使得开发改善性的治疗迟发性性腺功能减退的新疗法的商业动机减少了。在前列腺、头发、皮肤受雄激素缺乏影响的患者中,选择性雄激素受体调节剂已被证明可以提供合成代谢的好处。(目前,选择性雄激素受体调节剂的临床进展集中在有限定身体功能的临床终点的急性肌肉萎缩和低体重)。在具有有益的药理、理想的药代动力学的选择性雄激素受体调节剂应用于治疗迟发性男性性腺功能低下症前,其在男性性腺功能低下治疗中关于临床缺陷的更清晰的监管是必须的。 | Christopher C Coss Amanda Jones Michael L Hancock Mitchell S Steiner James T Dalton | 2014 | Asian Journal of Andrology2014，16，2： | 3 |
| 5 | Measurement of Schottky barrier height tuning using dielectric dipole insertion method at metal-semiconductor interfaces by photoelectron spectroscopy and electrical characterization techniques显示文摘 | COSS B E SIVASUBRAMANI P BRENNAN B | 2013 | J Vac Sci Technol B:Microelectron Nanometer Struct2013，31，02： | 1 |
| 6 | Near band edge Schottky barrier height modulation using high-κdielectric dipole tuning mechanism显示文摘 | COSS B E LOH W Y WALLACE R M | 2009 | Appl Phys Lett2009，95，22： | 1 |
| 7 | Increased topoisomerase llalpha expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis显示文摘 | Coss A Tosetto M Fox EJ | 2009 | Cancer Lett2009，276，： | 1 |
| 8 | Scavenging of hydrogen peroxide in the endosperm ofRicinus communis by ascor- bate peroxidase显示文摘 | Klapheck S Zimmer I Cosse H | 1990 | Plant Cell & Physiology1990，31，7： | 1 |
| 9 | Hypoxia-inducible factor-1-de-pendent overexpression of myeloid cell factor-1 protects hypoxiccelIs against tert-butyl hydroperoxide-induced apoptosis显示文摘 | Piret J P Minet E Cosse JP | 2005 | J Biolchem2005，280，10： | 1 |
| 10 | Willingness to pay or intention to pay: The attitude-behavior relationship in contingent valuation显示文摘 | Luzar E J Cosse K J | 1998 | The Journal of Socio- Economics1998，27，3： | 1 |
| 11 | Pancreatic Cancer and Drinking Water and Dietary Sources of Nitrate and Nitrite,CF Lynch,MH Ward显示文摘 | A Coss KP Cantor JS Reif | 2004 | American Journal of Epidemiology2004，159，7： | 1 |
| 12 | Heavy ion and proton induced single event transients in comparator 显示文摘 | NICHOLS D K COSS J R MIYAHIRA T F | 1996 | IEEE Trans Nucl Sci1996，43，6： | 1 |
| 13 | Electrophysiologically and Behaviorally Active Volatiles of Buffalo Gourd Root Powder for Corn Rootworm Beetles显示文摘 | Allard A. Cossé Thomas C. Baker | 1999 | Journal of Chemical Ecology1999，，1： | 1 |
| 14 | Alanine Aminotransferase Regulation by Androgens in Non-hepatic Tissues显示文摘 | Christopher Coss Matt Bauler Ramesh Narayanan Duane Miller James Dalton | 2012 | Pharmaceutical Research2012，，4： | 1 |
| 15 | Tumour hypoxia affects the responsiveness of cancer cells tochemotherapy and promotes cancer progression显示文摘 | COSSE J P MICHIELS C | 2008 | Anticancer Agents Med Chem2008，8，7： | 1 |
| 16 | Abduction stress and AP weightbearing radiography of purely ligamentous injury in the tarsometatarsal joint显示文摘 | Coss HS Manos RE Buoncristiani A | 1998 | Foot Ankle Int1998，19，： | 1 |
| 17 | BNIP3 protects HepG2 cells against etopo-side-induced cell death under hypoxia byan autophagy-independent pathway 显示文摘 | Cosse JP Rommelaere G Ninane N | 2010 | Biochem Pharmacol2010，80，8： | 1 |
| 18 | Lead - free at last 显示文摘 | COSS E | 2004 | Nature2004，432，： | 1 |
| 19 | Serum value of procalcitonin as a marker of intestinal damages:type,extension,and prognosis显示文摘 | Cosse C Sabbagh C Browet F | 2015 | Surg Endosc2015，29，11： | 1 |
| 20 | Microwave regeneration of activated carbon used for removal of solvents from vented air显示文摘 | COSS P M CHANG Y C | | 0，，04： | 1 |
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