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| 1 | Fulminant myocarditis in adults: a narrative review显示文摘Fulminant myocarditis(FM)is an uncommon syndrome characterized by sudden and severe hemodynamic compromise secondary to acute myocardial inflammation,often presenting as profound cardiogenic shock,life-threatening ventricular arrhythmias and/or electrical storm.FM may be refractory to conventional therapies and require mechanical circulatory support(MCS).The immune system has been recognized as playing a pivotal role in the pathophysiology of myocarditis,leading to an increased focus on immunosuppressive treatment strategies.Recent data have highlighted not only the fact that FM has significantly worse outcomes than non-FM,but that prognosis and management strategies of FM are heavily dependent on histological subtype,placing greater emphasis on the role of endomyocardial biopsy in diagnosis.The impact of subtype on severity and prognosis will likewise influence how aggressively the myocarditis is managed,including whether MCS is warranted.Many patients with refractory cardiogenic shock secondary to FM end up requiring MCS,with venoarterial extracorporeal membrane oxygenation demonstrating favorable survival rates,particularly when initiated prior to the development of multiorgan failure.Among the challenges facing the field are the need to more precisely identify immunopathophysiological pathways in order to develop targeted therapies,and the need to better optimize the timing and management of MCS to minimize complications and maximize outcomes. | Santiago Montero Darryl Abrams Enrico Ammirati Florent Huang Dirk WDonker Guillaume Hekimian Cosme García-García Antoni Bayes-Genis Alain Combes Matthieu Schmidt | 2022 | Journal of Geriatric Cardiology2022，19，2： | 3 |
| 2 | Application of the modulated temperature differential scanning calorimetry technique for the determination of the specific heat of copper nanofluids显示文摘 | E De Robertis E H H Cosme A Yu Kuznetsov | 2012 | Applied Thermal Engineering2012，41，8： | 1 |
| 3 | Krukenberg tumor secondary to gastric carcinoma in a women in her eighth month of pregnancy显示文摘 | Cosme A Ojeda E Bujanda L | 2001 | Gastroenterol Hepatol2001，24，1： | 1 |
| 4 | Antimicrobial Susceptibility-Guided therapy versus empirical concomitant therapy for eradication of helicobacter pylori in a region with high rate of clarithromycin resistance显示文摘 | COSME A LIZASOAN J MONTES M | 2016 | Helicobacter2016，21，1： | 1 |
| 5 | Malignant eolorectal polyps 显示文摘 | Bujanda L Cosme A Gil I | 2010 | WorldJ Gastroenterol2010，，25： | 1 |
| 6 | Long-term follow-up of 1000 patients cured of Helicobacter pylori infection following an episode of peptic ulcer bleeding显示文摘 | Gisbert JP Calvet X Cosme A | 2012 | The American Journal of Gastroenterol-ogy2012，107，8： | 1 |
| 7 | Crystal structure of human cytochrome P450 2C9 with bound warfarin 显示文摘 | WILLIAMS P A COSME J WARD A | 2003 | Nature2003，424，6947： | 1 |
| 8 | Malignant colorectal polyps 显示文摘 | Bujanda L Cosme A Gil I | 2010 | World J Gastroenterol2010，16，25： | 1 |
| 9 | Novel serum and urine markers for pediatric appendicitis显示文摘 | KHARBANDA A B RAI A J COSME Y | 2012 | Acad Emerg Med2012，19，1： | 1 |
| 10 | Crystal struc- tures of human cytochrome P450 3A4 bound to metyrapone and progesterone 显示文摘 | Williams P A Cosme J Vinkovic D M | 2004 | Science2004，305，5684： | 1 |
| 11 | Toxoplasma gondii infection in workers occupationally exposed to raw meat显示文摘 | Cosme A Oliver L Sergio E | 2011 | Occup Med(Lond)2011，61，4： | 1 |
| 12 | Congenital intrahepatic venous shunt as a cause of hepatic eneephalopathy 显示文摘 | Cosme Jimenez A Bujanda Ferndndez de Pierola L Poch Zapirain M | 1995 | Gastroenteol Hepatol1995，28，9： | 1 |
| 13 | Mammalian micro- somal cytochrome P450 monooxygenase: Structural adapta- tions for membrane binding and functional diversity显示文摘 | Williams P A Cosme J Sridhar V | 2000 | Mol Cell2000，5，： | 1 |
| 14 | Toxicology and biodistribution study of CIGB-230, a DNA vaccine against hepatitis C virus 显示文摘 | Bacardi D Amador-Cafiizares Y Cosme K Urquiza D Sudrez J Marante J Vifia A V6zquez A Concepci6n J Pupo M Aldana L Soria Y Romero J Madrigal R Martinez L Herndndez L Gonzdlez I Duefias-Carrera S | 2009 | Hum Exp Toxicol2009，28，8： | 1 |
| 15 | Pyogenic liver abscesses of bacterial origin of 45 cases 显示文摘 | Barrio J Cosme A Ojeda E | 2000 | Rev Esp Enferm Dig2000，92，： | 1 |
| 16 | Malignant colorectal polyps显示文摘 | BujandaL Cosme A Gil I | 2010 | World J Gastroenterol2010，16，25： | 1 |
| 17 | Evaluation of alpha1 -antitrypsin and the levels of mRNA expression of matrix metallopro-teinase-7,urokinase type plasminogen activator receptor and COX-2for the diagnosis of colorectal cancer显示文摘 | Bujanda L Sarasqueta C Cosme A | 2013 | PLoS One2013，8，51： | 1 |
| 18 | A differential evolution approach for solving constrained rain-max optimization problems 显示文摘 | Gilberto A S Segundo A Renato A Krohling B Rodrigo C Cosme | 2012 | Expert Systems with Applications2012，39，13： | 1 |
| 19 | Malignant coloreetal polyps显示文摘 | Bujanda L Cosme A Gil I | 2010 | World J Gastroentero12010，16，25： | 1 |
| 20 | Application of Computer Aided Engineering in the Design of Heavy - Duty Truck Frames, International Truck & Bus Meeting & Exposition, Detroit, Michigan 显示文摘 | COSME C GHASEMI A GANDEVIA J | 1999 | November1999，，5： | 1 |
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