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| 1 | 婴儿和儿童睾丸卵黄囊瘤33例并临床病理特征分析显示文摘作者收集1918~2014年诊断的发生于5~71个月(平均20.7个月)的男孩睾丸纯卵黄囊瘤33例。除1例外所有患者均接受睾丸切除,18例同时行淋巴结清扫术(全部阴性);21例接受化疗,12例接受放疗。 | Cornejo K M Frazier L Lee R S 魏建国 许春伟 | 2015 | 临床与实验病理学杂志2015，31，9： | 11 |
| 2 | T_3-induced liver AMP-activated protein kinase signaling:Redox dependency and upregulation of downstream targets显示文摘AIM:To investigate the redox dependency and promotion of downstream targets in thyroid hormone(T3)-induced AMP-activated protein kinase(AMPK)signaling as cellular energy sensor to limit metabolic stresses in the liver.METHODS:Fed male Sprague-Dawley rats were given a single ip dose of 0.1 mg T3/kg or T3 vehicle(Na OH0.1 N;controls)and studied at 8 or 24 h after treatment.Separate groups of animals received 500 mg N-acetylcysteine(NAC)/kg or saline ip 30 min prior T3.Measurements included plasma and liver 8-isoprostane and serumβ-hydroxybutyrate levels(ELISA),hepaticlevels of m RNAs(q PCR),proteins(Western blot),and phosphorylated AMPK(ELISA).RESULTS:T3 upregulates AMPK signaling,including the upstream kinases Ca2+-calmodulin-dependent protein kinase kinase-βand transforming growth factor-β-activated kinase-1,with T3-induced reactive oxygen species having a causal role due to its suppression by pretreatment with the antioxidant NAC.Accordingly,AMPK targets acetyl-Co A carboxylase and cyclic AMP response element binding protein are phosphorylated,with the concomitant carnitine palmitoyltransferase-1α(CPT-1α)activation and higher expression of peroxisome proliferator-activated receptor-γco-activator-1αand that of the fatty acid oxidation(FAO)-related enzymes CPT-1α,acyl-Co A oxidase 1,and acylCo A thioesterase 2.Under these conditions,T3 induced a significant increase in the serum levels ofβ-hydroxybutyrate,a surrogate marker for hepatic FAO.CONCLUSION:T3 administration activates liver AMPK signaling in a redox-dependent manner,leading to FAO enhancement as evidenced by the consequent ketogenic response,which may constitute a key molecular mechanism regulating energy dynamics to support T3preconditioning against ischemia-reperfusion injury. | Luis A Videla Virginia Fernández Pamela Cornejo Romina Vargas Paula Morales Juan Ceballo Alvaro Fischer Nicolás Escudero Oscar Escobar | 2014 | World Journal of Gastroenterology2014，20，46： | 3 |
| 3 | Phytoremediation of Metal-Polluted Soils by Arbuscular Mycorrhizal Fungi显示文摘 | Sebastián Meier Fernando Borie Nanthi Bolan Pablo Cornejo | 2012 | Critical Reviews in Environmental Science and Technology2012，，7： | 2 |
| 4 | Enzymatic heme oxygenase activity in soluble extracts of the unicellular red alga,Cyanidium caldarium显示文摘 | BEALE S I CORNEJO J | 1984 | Arch Biochem Biophys1984，235，2： | 1 |
| 5 | Reactions of genistein with alkylperoxyl radicals显示文摘 | Arora A Valcic S Cornejo S | 2000 | Chem Res Toxicol2000，13，7： | 1 |
| 6 | A single episode of neonatal seizures permanently alters glutamatergic synapses显示文摘 | Cornejo BJ Mesches MH Coultrap S | 2007 | Ann Neurol2007，61，5： | 1 |
| 7 | Removing prometrone from water by clays and organic clays 显示文摘 | HERMOSIN M C CORNEJO J | 1998 | Chemosphere1998，37，2： | 1 |
| 8 | Studies on the decontamination of air by Chilean plants显示文摘 | Cornejo J J Munoz F G Ma C Y Stewart A J | 1999 | Ecotoxicology1999，8，： | 1 |
| 9 | Studies on the origin of microorganisms multiplying during manufacture of dry cured raw ham显示文摘 | CORNEJO I CARRASCOSA A V MARIN M E | 1992 | Fleischwirtschaft1992，72，10： | 1 |
| 10 | Use of modified montmorillonite to reduce herbicide leaching in sports turf surfaces: laboratory and field experiments 显示文摘 | CORNEJO L CELIS R DOMINGUEZ C | 2008 | Appl Clay Sci2008，42，： | 1 |
| 11 | The first immobilization of pyridine-bis(oxazoline) chiral ligands显示文摘 | CORNEJO A FRAILE J M GARCIA J I | | 0，，22： | 1 |
| 12 | Occurrence and distribution of microorganisms on the surface of dry cured Spanish ham 显示文摘 | CARRASCOSA A V CORNEJO I MARIN M E | 1992 | Fleischwirtschaft1992，72，7： | 1 |
| 13 | Effects of pronepositioning on lung protection in patients with acuterespiratory distress syndrome显示文摘 | Cornejo RA Diaz JC Tobar EA | 2013 | Am J Respir Crit Care Med2013，188，4： | 1 |
| 14 | El Salvador,Chile porohyry copper deposit revisited:Geological and geochronoligic framework显示文摘 | CORNEJO P TOSDAL R M MPODOZIS C | 1997 | International Geology Review1997，39，1： | 1 |
| 15 | Characterization of micrococcaceae strains selected as potential starter cultures to Spanish dry-cured ham processes显示文摘 | CARRASCOSA A V CORNEJO I | 1991 | Fleischwirtschaft1991，71，10： | 1 |
| 16 | Oncofetal protein IMP3 : a useful diagnostic biomarker for leiomyosarcoma显示文摘 | Cornejo K Shi M Jiang Z | 2012 | Hum Pathol2012，43，10： | 1 |
| 17 | Intestinal perforation associated with rituximab therapy for post-transplant lymphoproliferative disorder after liver transplantation显示文摘 | Agustin Cornejo Mary Bohnenblust Catherine Harris Gregory A. Abrahamian | 2009 | Cancer Chemotherapy and Pharmacology2009，，4： | 1 |
| 18 | Hydrotalcite as sorbent for trinitrophenol sorption capacity and mechanism显示文摘 | Hermosín M C Pavlovic I Ulibarri M A Cornejo J | 1996 | Water research1996，30，1： | 1 |
| 19 | Comparative study of D1 and D2 ganglionic dissection in advanced gastric cancer at Rebagliati Hospital显示文摘 | Cornejo C Portanova M | 2006 | Rev Gastroenterol Peru2006，26，4： | 1 |
| 20 | A single episode of neonatal seizures permanently alters glutamatergic synapses显示文摘 | Cornejo BJ Mesches MH Coultrap S | 2007 | Ann Neurol2007，61，5： | 1 |
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