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1Unusual presentations of eosinophilic gastroenteritis:Case series and review of literature显示文摘Eosinophilic gastroenteritis (EG) is an uncommon disease characterized by focal or diffuse eosinophilic infiltration of the gastrointestinal tract, and is usually associated with dyspepsia, diarrhea and peripheral eosinophilia. Diffuse gastrointestinal tract and colonic involvement are uncommon. The endoscopic appearance may vary from normal to mucosal nodularity and ulceration. Gastrointestinal obstruction is unusual and is associated with predominantly muscular disease. We present five unusual cases of EG associated with gastric outlet and duodenal obstruction. Two cases presented with acute pancreatitis and one had a history of pancreatitis. Four cases responded well to medical therapy and one had recurrent gastric outlet obstruction that required surgery. Four out of the five cases had endoscopic and histological evidence of esophagitis and two had colitis. Two patients had ascites. These cases reaffirm that EG is a disorder with protean manifestations and may involve the entire gastrointestinal tract. Gastric outlet and/or small bowel obstruction is an important though uncommon presentation of EG. It may also present as esophagitis, gastritis with polypoid lesions, ulcers or erosions, colitis and pancreatitis and may mimic malignancy.Rafiq A Sheikh Thomas P Prindiville R Erick Pecha Boris H Ruebner 2009World Journal of Gastroenterology2009,15,17:43
2Endoscopic ultrasound elastography for evaluation of lymph nodes and pancreatic masses:A multicenter study显示文摘AIM:To evaluate the ability of endoscopic ultrasound(EUS) elastography to distinguish benign from malignant pancreatic masses and lymph nodes.METHODS:A multicenter study was conducted and included 222 patients who underwent EUS examination with assessment of a pancreatic mass(n=121) or lymph node(n=101).The classification as benign or malignant,based on the real time elastography pattern,was compared with the classif ication based on the B-mode EUS images and with the fi nal diagnosis obtained by EUS-guided fi ne needle aspiration(EUS-FNA) and/or by surgical pathology.An interobserver study was performed.RESULTS:The sensitivity and specificity of EUS elastography to differentiate benign from malignant pancreatic lesions are 92.3% and 80.0%,respectively,compared to 92.3% and 68.9%,respectively,for the conventional B-mode images.The sensitivity and specificity of EUS elastography to differentiate benign from malignant lymph nodes was 91.8% and 82.5%,respectively,compared to 78.6% and 50.0%,respectively,for the B-mode images.The kappa coefficient was 0.785 for the pancreatic masses and 0.657 for the lymph nodes.CONCLUSION:EUS elastography is superior compared to conventional B-mode imaging and appears to be able to distinguish benign from malignant pancreatic masses and lymph nodes with a high sensitivity,specificity and accuracy.It might be reserved as a second line examination to help characterise pancreatic masses after negative EUS-FNA and might increase the yield of EUS-FNA for lymph nodes.Marc Giovannini Botelberge Thomas Bories Erwan Pesenti Christian Caillol Fabrice Esterni Benjamin Monges Geneviève Arcidiacono Paolo Deprez Pierre Yeung Robert Schimdt Walter Schrader Hanz Szymanski Carl Dietrich Christoph Eisendrath Pierre Van Laethem Jean-Luc Devière Jacques Vilmann Peter Saftoiu Andrian 2009World Journal of Gastroenterology2009,15,13:48
3Role of transcatheter arterial embolization for massive bleeding from gastroduodenal ulcers显示文摘Intractable bleeding from gastric and duodenal ulcers is associated with significant morbidity and mortality. Aggressive treatment with early endoscopic hemostasis is essential for a favourable outcome. In as many as 12%-17% of patients,endoscopy is either not available or unsuccessful. Endovascular therapy with selective catheterization of the culprit vessel and injection of embolic material has emerged as an alternative to emergent operative intervention in high-risk patients. There has not been a systematic literature review to assess the role for embolotherapy in the treatment of acute upper gastrointestinal bleeding from gastroduo-denal ulcers after failed endoscopic hemostasis. Here,we present an overview of indications,techniques,and clinical outcomes after endovascular embolization of acute peptic-ulcer bleeding. Topics of particular relevance to technical and clinical success are also discussed. Our review shows that transcatheter arterial embolization is a safe alternative to surgery for massive gastroduodenal bleeding that is refractory to endoscopic treatment,can be performed with high technical and clinical success rates,and should be considered the salvage treatment of choice in patients at high surgical risk.Romaric Loffroy Boris Guiu 2009World Journal of Gastroenterology2009,15,47:27
4三电平和两电平逆变器效率分析与比较显示文摘在分析、计算二极管箝位型三电平逆变器和两电平逆变器的通态损耗、开关损耗以及输出滤波电感损耗的基础上,对这两种逆变器的损耗、效率进行了比较。Boris L Corral Martinez 马柯 李睿 徐德鸿 2009电力电子技术2009,43,7:25
5花青素抗氧化损伤及细胞凋亡的作用研究显示文摘目的:探索花青素对H2O2引起的Huh7细胞氧化应激、细胞凋亡的作用及其机制。方法:对H2O2和花青素干预培养的Huh7细胞,应用MTT法检测细胞活力,荧光探针DCFH-DA测定细胞内活性氧(ROS)生成量,免疫印迹测定Akt、磷酸化激活的c-Jun蛋白水平。结果:H2O20.8mmol/L孵育1小时可显著诱导Huh7细胞损伤,细胞活力下降到(49.27±3.2)%,ROS生成量是未处理细胞的3.56倍。细胞经花青素50μmol/L与H2O2共孵育后,细胞存活率提高到(81.2±2.34)%;花青素能显著抑制H2O2引起的Huh7细胞ROS生成,ROS生成下降74%(P<0.01)。花青素抑制H2O2引起Huh7细胞死亡和ROS生成的效应随剂量增加而加强。花青素抑制H2O2激发Huh7细胞磷酸化c-Jun表达,提高细胞Akt水平。结论:花青素抑制H2O2引起的Huh7细胞氧化应激损伤所导致的细胞死亡,其作用机制在于减少细胞内活性氧生成,抑制H2O2激活磷酸化c-Jun,提高细胞Akt水平。余晶 鲍中英 徐玉敏 Vladimir Khaoustov Boris Yoffe 2009中西医结合肝病杂志2009,19,1:21
6浅海中孤立子内波引起的声能量起伏显示文摘当孤立子内波的波阵面与声传播路径所成角度较大时,简正波耦合是导致声信号起伏的主要因素。研究了浅海中孤立子内波引起的声能量起伏规律,给出声场起伏的耦合简正波表达式,并使用抛物方程模型进行仿真。数值分析表明,接收点声强随时间变化呈准周期性。在频谱图中能够得到声强起伏的主导频率,主导频率与孤立子内波沿声传播路径的移动速度成正比,与无扰动波导中简正波在距离上的干涉周期(对应于射线理论中临界声线的跨度)成反比,与孤立子内波的形状无关。此外,对声强频谱的垂直结构进行了分析,该结构与对声场起伏起主要作用简正波的本征函数相关。秦继兴 KATSNELSON Boris 李整林 张仁和 骆文于 2016声学学报2016,41,2:21
7Helicobacter pylori and oral pathology:Relationship with the gastric infection显示文摘Helicobacter pylori(H.pylori)has been found in the oral cavity and stomach,and its infection is one of the most frequent worldwide.We reviewed the literature and conducted a Topic Highlight,which identified studies reporting an association between H.pylori-infection in the oral cavity and H.pylori-positive stomach bacterium.This work was designed to determine whether H.pylori is the etiologic agent in periodontal disease,recurrent aphthous stomatitis(RAS),squamous cell carcinoma,burning and halitosis.Record selection focused on the highest quality studies and meta-analyses.We selected 48 articles reporting on the association between saliva and plaque and H.pylori-infection.In order to assess periodontal disease data,we included 12 clinical trials and 1 meta-analysis.We evaluated 13 published articles that addressed the potential association with RAS,and 6 with squamous cell carcinoma.Fourteen publications focused on our questions on burning and halitosis.There is a close relation between H.pylori infection in the oral cavity and the stomach.The mouth is the first extra-gastric reservoir.Regarding the role of H.pylori in the etiology of squamous cell carcinoma,no evidence is still available.Isabel Adler Andrea Muio Silvia Aguas Laura Harada Mariana Diaz Adriana Lence Mario Labbrozzi Juan Manuel Muio Boris Elsner Alejandra Avagnina Valeria Denninghoff 2014World Journal of Gastroenterology2014,20,29:21
8Gold nanorods with a hematoporphyrin-loaded silica shell for dual-modality photodynamic and photothermal treatment of tumors in vivo显示文摘由一个金 nanorod 核心和与 hematoporphyrin (HP ) 做的 mesoporous 硅石壳组成的 Nanocomposites (NC ) 被制作了以便由在 vivo 联合 photothermal 和光力学的治疗(太平洋夏季时间 + PTT ) 改进癌症治疗的效率。除了 810830 nm 附近的长波长的电浆子回声,制作 NC 展出了相应的一座 400-nm 吸收度山峰围住 HP,在 632.5-nm Q 乐队附近在 633-nm 刺激下面产生了汗衫氧,并且生产了在 808-nm 下面的热在红外线附近(NIR ) 激光照耀。这些形式被用于联合太平洋夏季时间 + PTT 治疗大(大约 3 cm3 ) 在有一只 xenorafted 肿瘤老鼠的 vivo 的稳固的肿瘤当模特儿。NC 直接被注入肿瘤并且与 633-nm 和 808-nm 激光同时照耀刺激联合光力学并且 NC 的 photothermal 活动。联合治疗的效率被光连贯断层摄影术评估,组织学的分析,并且由肿瘤体积生长的大小在一个 21 天的时期期间。调停 NC 的太平洋夏季时间在组织组织学并且到导致了弱变化一中等在肿瘤体积的 20% 减少。相反,联合太平洋夏季时间 + PTT 处理导致了大区域的肿瘤坏死并且在肿瘤体积导致了戏剧的减少。Georgy Terentyuk Elizaveta Panfilova Vitaly Khanadeev Daniil Chumakov Elina Genina Alexey Bashkatov Valery Tuchin Alia Bucharskaya Galina Maslyakova Nikolai Khlebtsov Boris Khlebtsov 2014Nano Research2014,7,3:17
9On-the-fly active learning of interpretable Bayesian force fields for atomistic rare events显示文摘Machine learned force fields typically require manual construction of training sets consisting of thousands of first principles calculations,which can result in low training efficiency and unpredictable errors when applied to structures not represented in the training set of the model.This severely limits the practical application of these models in systems with dynamics governed by important rare events,such as chemical reactions and diffusion.We present an adaptive Bayesian inference method for automating the training of interpretable,low-dimensional,and multi-element interatomic force fields using structures drawn on the fly from molecular dynamics simulations.Within an active learning framework,the internal uncertainty of a Gaussian process regression model is used to decide whether to accept the model prediction or to perform a first principles calculation to augment the training set of the model.The method is applied to a range of single-and multi-element systems and shown to achieve a favorable balance of accuracy and computational efficiency,while requiring a minimal amount of ab initio training data.We provide a fully opensource implementation of our method,as well as a procedure to map trained models to computationally efficient tabulated force fields.Jonathan Vandermause Steven B.Torrisi Simon Batzner Yu Xie Lixin Sun Alexie M.Kolpak Boris Kozinsky 2020npj Computational Materials2020,,1:17
10国际化人才需求下中国高校毕业生就业能力发展研究——基于在华德企对中国高校毕业生的期望及实现情况调研显示文摘在世界经济全球化的大背景下,国际化人才需求成为高校人才培养的风向标之一。中国高校所培养的毕业生是否能够满足国际化人才需求?本研究以此问题为出发点,在5200家在华德企中随机抽取了218家在华德企为研究样本,对在这些企业入职1—5年的中国高校毕业生的就业基本情况、能力发展情况,特别是企业对他们的期望及实现情况差异进行调研。调研结果表明,中国高校毕业生普遍在学科知识或专业技能等硬实力方面受到较多肯定,但在社交能力、个人素养等软实力方面距企业的要求存在较大差距。根据这一结果,结合面向30名在德企工作的中国高校毕业生的访谈,提出改革中国高校的培养方式:加快提升我国职业教育的育人水准,加快课程改革的进程,构建有利于综合素养提升的校园生活,以及提升大学生就业指导的专业水准。祝智庭 Boris Wesemann 闫寒冰 王诗蓓 李笑樱 王巍 Robert A.Sedlák 2021华东师范大学学报(教育科学版)2021,39,11:13
11Microstructure and mechanical properties of Mg-5Li-1Al sheets prepared by accumulative roll bonding显示文摘Ultrafine-grain and high-strength Mg-5Li-1Al sheets were prepared by accumulative roll bonding(ARB)process. Evolution of microstructure and mechanical properties of ARB-processed Mg-5Li-1Al sheets was investigated.Results show that, during ARB process, the evolution of deformation mechanism of t Mg-5Li-1Al alloy is as follows: twinning deformation, shear deformation, forming macro shear zone, and finally dynamic recrystallization(DRX). The grain refining mechanism changes from twin DRX to rotation DRX. With the increase in ARB cycles, strength of the Mg-5Li-1Al sheets is enhanced, whilst elongation varies slightly.With the increase in rolling cycles, anisotropy of mechanical properties decreases. It is conclusive that strain hardening and grain refinement dominate the strengthening mechanism of Mg-5Li-1Al alloy.Legan Hou Tianzi Wang Ruizhi Wu Jinghuai Zhang Milin Zhang Anping Dong Baode Sun Sergey Betsofen Boris Krit 2018Journal of Materials Science & Technology2018,34,2:13
12The transformation of LPSO type in Mg-4Y-2Er-2Zn-0.6Zr and its response to the mechanical properties and damping capacities显示文摘The transformation of LPSO type in Mg-4Y-2Er-2Zn-0.6Zr during heat treatment and its influence on damping and mechanical properties are reported in this work.Prior to heat treatment,the alloy consisted of a-Mg matrix and lamellar 14H LPSO phases.After 510℃heat treatment,lamellae shortened,and their content decreased.Upon 8h heat treatment,block 18R LPSO phases formed at the grain boundaries while 14H LPSO lamellae disappeared.Presence of block 18R LPSO phases improved mechanical and damping properties of the alloy.The corresponding mechanisms of the influence of LPSO type and morphology on mechanical and damping capacities are discussed.Dan Wang Huajie Wu Ruizhi Wu Yang Wang Jinghuai Zhang Sergey Betsofen Boris Krit Legan Hou Turahodjayev Nodir 2020Journal of Magnesium and Alloys2020,8,3:13
13Controlled Nanocutting of Graphene显示文摘Rapid progress in graphene-based applications is calling for new processing techniques for creating graphene components with different shapes,sizes,and edge structures.Here we report a controlled cutting process for graphene sheets,using nickel nanoparticles as a knife that cuts with nanoscale precision.The cutting proceeds via catalytic hydrogenation of the graphene lattice,and can generate graphene pieces with specifi c zigzag or armchair edges.The size of the nanoparticle dictates the edge structure that is produced during the cutting.The cutting occurs along straight lines and along symmetry lines,defined by angles of 60ºor 120º,and is defl ected at free edges or defects,allowing practical control of graphene nano-engineering.Lijie Ci Zhiping Xu Lili Wang Wei Gao Feng Ding Kevin F.Kelly Boris I.Yakobson Pulickel M.Ajayan 2008Nano Research2008,1,2:11
14Biological mesh reconstruction of the pelvic floor following abdominoperineal excision for cancer:A review显示文摘Extralevator abdominoperineal excision and pelvic exenteration are mutilating operations that leave wide perineal wounds.Such large wounds are prone to infection and perineal herniation,and their closure is a major concern to most surgeons.Different approaches to the perineal repair exist,varying from primary or mesh closure to myocutaneous flaps.Each technique has its own associated advantages and potential complications and the ideal approach is still debated.In the present study,we reviewed the current literature and our own local data regarding the use of biological mesh for perineal wound closure.Current evidence suggests that the use of biological mesh carries an acceptable risk of wound complications compared to primary closure and is similar to flap reconstruction.In addition,the rate of perineal hernia is lower in early follow-up,while long-term hernia occurrence appears to be similar between the different techniques.Finally,it is an easy and quick reconstruction method.Although more expensive than primary closure,the cost associated with the use of a biological mesh is at least equal,if not less,than flap reconstruction.Boris Schiltz Nicolas Christian Buchs Marta Penna Cosimo Riccardo Scarpa Emilie Liot Philippe Morel Frederic Ris 2017World Journal of Clinical Oncology2017,8,3:10
15Liver venous deprivation versus portal vein embolization before major hepatectomy:future liver remnant volumetric and functional changes显示文摘Background:We previously showed that embolization of portal inflow and hepatic vein(HV)outflow(liver venous deprivation,LVD)promotes future liver remnant(FLR)volume(FLR-V)and function(FLR-F)gain.Here,we compared FLR-V and FLR-F changes after portal vein embolization(PVE)and LVD.Methods:This study included all patients referred for liver preparation before major hepatectomy over 26 months.Exclusion criteria were:unavailable baseline/follow-up imaging,cirrhosis,Klatskin tumor,two-stage hepatectomy.99mTc-mebrofenin SPECT-CT was performed at baseline and at day 7,14 and 21 after PVE or LVD.FLR-V and FLR-F variations were compared using multivariate generalized linear mixed models(joint modelling)with/without missing data imputation.Results:Baseline FLR-F was lower in the LVD(n=29)than PVE group(n=22)(P<0.001).Technical success was 100%in both groups without any major complication.Changes in FLR-V at day 14 and 21(+14.2%vs.+50%,P=0.002;and+18.6%vs.+52.6%,P=0.001),and in FLR-F at day 7,14 and 21(+23.1%vs.+54.3%,P=0.02;+17.6%vs.+56.1%,P=0.006;and+29.8%vs.+63.9%,P<0.001)differed between PVE and LVD group.LVD(P=0.009),age(P=0.027)and baseline FLR-V(P=0.001)independently predicted FLR-V variations,whereas only LVD(P=0.01)predicted FLR-F changes.After missing data handling,LVD remained an independent predictor of FLR-V and FLR-F variations.Conclusions:LVD is safe and provides greater FLR-V and FLR-F increase than PVE.These results are now evaluated in the HYPERLIV-01 multicenter randomized trial.Boris Guiu François Quenet Fabrizio Panaro Lauranne Piron Christophe Cassinotto Astrid Herrerro François-Régis Souche Margaux Hermida Marie-Ange Pierredon-Foulongne Ali Belgour Serge Aho-Glele Emmanuel Deshayes 2020Hepatobiliary Surgery and Nutrition2020,9,5:10
16一个基于XML的Agent通信框架显示文摘Agent通信是多Agent系统的核心活动之一 ,是Agent相互协调、合作、竞争和完成任务的基础。Agent通信语言为此提供了一种高层次、灵活、通用的通信模式。在KQML和FIPA ACL的基础上提出通用Agent通信语言的概念 ,阐述构建通用ACL的重要性和可行性 ,深入讨论一个基于XML的Agent通信框架 ,最后给出实例。魏晓斌 Rainer Unland Boris Bacmendo 2001计算机应用研究2001,18,10:10
17新型电磁式电压互感器显示文摘介绍了一种新型电磁式电压互感器,阐述了电磁式和电容式电压互感器技术特性的区别。刘玉凤 Boris Bojanic 2007变压器2007,44,1:9
18火山灰对富有机质页岩形成的影响——以西西伯利亚盆地中生界巴热诺夫组为例显示文摘西西伯利亚盆地上侏罗统-下白垩统巴热诺夫组硅质-钙质富有机质泥页岩总有机碳(TOC)含量高且有机质成熟度适中,是俄罗斯目前页岩油的勘探首选目的层系。近年研究表明,该套富有机质页岩层段发育数套厘米-毫米级的火山灰夹层,具黄色荧光,岩心薄片见大量沸石等火山灰蚀变矿物,使该区火山灰与富有机质形成的相互关系引起关注。以该盆地的巴热诺夫组为例,介绍了火山灰对该区富有机质页岩形成的影响。巴热诺夫组的地质-地球化学分析表明,在火山灰发育同期沉积的富有机质层段中不仅硅、磷等营养元素含量高,而且钡、锰、钼、铀等藻类繁殖催化元素含量也高,推测火山灰携带物质促进了巴热诺夫页岩沉积时期古生物的大量繁殖甚至爆发,为富有机质的形成奠定了物质基础;同时,在火山灰发育层段之上的富有机质泥页岩中大量发育草莓状黄铁矿,且呈层状分布,Co/Ni比值小于1,S/Fe比值偏高,指示火山灰喷发之后形成缺氧的强还原环境,有利于泥页岩中有机质的保存;火山灰发育井区TOC含量高(多>7%),有机质成熟度与邻近火山灰不发育区相比偏高(R o=0.7%~1.1%),生烃潜力高且已达到生油高峰,推测可能火山灰携带的钼、镍等元素促进了热催化生油阶段干酪根的成烃演化;火山灰发育的富有机质页岩层段常见藻类纹层与碳酸盐岩纹层互层,多见层间孔缝,利于页岩油气的运移。因此,火山灰与巴热诺夫组富有机质页岩的形成具有一定的内在联系,火山灰不仅能够提高沉积时期的古生产力和保存条件,促进有机质的成烃演化,而且利于形成富有机质交互纹层,易于后期压裂开发。梁新平 金之钧 刘全有 Shpilman Alexander 李鹏 Morozov Vladimir Uspensky Boris 2021石油与天然气地质2021,42,1:9
19Spontaneous Twist and Intrinsic Instabilities of Pristine Graphene Nanoribbons显示文摘In pristine graphene ribbons,disruption of the aromatic bond network results in depopulation of covalent orbitals and tends to elongate the edge,with an effective force of fe~2 eV/Å(larger for armchair edges than for zigzag edges,according to calculations).This force can have quite striking macroscopic manifestations in the case of narrow ribbons,as it favors their spontaneous twisting,resulting in the parallel edges forming a double helix,resembling DNA,with a pitchλt of about 1520 lattice parameters.Through atomistic simulations,we investigate how the torsionτ~1/λt decreases with the width of the ribbon,and observe its bifurcation:the twist of wider ribbons abruptly vanishes and instead the corrugation localizes near the edges.The length-scale(λe)of the emerging sinusoidal“frill”at the edge is fully determined by the intrinsic parameters of graphene,namely its bending stiffness D=1.5 eV and the edge force fe withλe~D/fe.Analysis reveals other warping configurations and suggests their sensitivity to the chemical passivation of the edges,leading to possible applications in sensors.Ksenia V.Bets Boris I.Yakobson 2009Nano Research2009,2,2:9
20水平管内水环输送模拟稠油减阻特性显示文摘基于自主设计加工并搭建的水环输送稠油减阻模拟管路系统,采用500#白油模拟稠油,试验研究了稠油在水环作用下的水平管流阻力特性,分析了油相表观流速(0.3~1.0m/s)、水相表观流速(0.11~0.72m/s)及入口含水率(0.13~0.49)对水润滑管流流型特征及减阻效果的影响。结果表明:环状水膜可有效隔离并润滑油壁界面,油-水两相流流型总体上呈稳定的偏心环状流结构;水环输送可大幅降低管道输送过程中的压降,其压降值仅为相同油流量下纯油输送压降的1/55~1/27;当入口含水率为0.13~0.27时,水环输送的效能显著,输油效率均高于40;油相表观流速和入口含水率的增加会增大单位管长压降,降低水环输送的减阻效果和输油效能。敬加强 尹晓云 MASTOBAEV Boris N VALEEV Anvar R 孙杰 王思汗 刘华平 庄乐泉 范峥嵘 2021化工进展2021,40,2:9
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