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9篇 您的检索式:作者名="Conglei"
    题名 作者 年代 出处 被引量
1Steering data quality with visual analytics:The complexity challenge显示文摘Data quality management,especially data cleansing,has been extensively studied for many years in the areas of data management and visual analytics.In the paper,we first review and explore the relevant work from the research areas of data management,visual analytics and human-computer interaction.Then for different types of data such as multimedia data,textual data,trajectory data,and graph data,we summarize the common methods for improving data quality by leveraging data cleansing techniques at different analysis stages.Based on a thorough analysis,we propose a general visual analytics framework for interactively cleansing data.Finally,the challenges and opportunities are analyzed and discussed in the context of data and humans.Shixia Liu Gennady Andrienko Yingcai Wu Nan Cao Liu Jiang Conglei Shi Yu-Shuen Wang Seokhee Hong 2018Visual Informatics2018,2,4:5
2Numerical investigation of bumps and oscillation in the cylindrical membrane inflation显示文摘WANG Conglei SUN Jianhong XU Changyue 2014Applied Mechanics and Materials2014,,:1
3TextFlow:Towards Beiter Understanding of Evolving Topics in Text显示文摘Weiwei Cui Shixia Liu Li Tan Conglei Shi Yangqiu Song Zekai Gao Huamin Qu Xin Tong 0,,12:1
4Levera- ging integrated information to extract query subtopics for search result diversification 显示文摘ZHENG Wei FANG Hui YAO Conglei 2014Information Retrieval2014,17,1:1
5Design and analysis of contracts for software outsourcing显示文摘Dey D Fan Ming Hang Conglei 2010Information Systems Re- search2010,21,1:1
6Design and Analysis of Contracts for Software Outsourcing显示文摘Debabrata Dey Ming Fan Conglei Zhang 2010Information Systems Research2010,,1:1
7Platelets and platelet alloantigens:Lessons from human patients and animal models of fetal and neonatal alloimmune thrombocytopenia显示文摘Platelets play critical roles in hemostasis and thrombosis.Emerging evidence indicates that they are versatile cells and also involved in many other physiological processes and disease states.Fetal and neonatal alloimmune thrombocytopenia(FNAIT)is a life threatening bleeding disorder caused by fetal platelet destruction by maternal alloantibodies developed during pregnancy.Gene polymorphisms cause platelet surface protein incompatibilities between mother and fetus,and ultimately lead to maternal alloimmunization.FNAIT is the most common cause of intracranial hemorrhage in full-term infants and can also lead to intrauterine growth retardation and miscarriage.Proper diagnosis,prevention and treatment of FNAIT is challenging due to insufficient knowledge of the disease and a lack of routine screening as well as its frequent occurrence in first pregnancies.Given the ethical difficulties in performing basic research on human fetuses and neonates,animal models are essential to improve our understanding of the pathogenesis and treatment of FNAIT.The aim of this review is to provide an overview on platelets,hemostasis and thrombocytopenia with a focus on the advancements made in FNAIT by utilizing animal models.Brian Vadasz Pingguo Chen Issaka Yougbare Darko Zdravic June Li Conglei Li Naadiya Carrim Heyu Ni 2015Genes & Diseases2015,2,2:1
8Paeoniflorin prevents hepatic fibrosis of Schistosomiasis japonica by inhibiting TGF-β1 production from macrophages in mice显示文摘In order to investigate the effect of paeoniflorin(PAE)on hepatic fibrosis of mice with Schistosomiasis japonica in vivo and in vitro,a model of hepatic fibrosis caused by schistosomiasis was established in mice infected with cercariae of Schistosoma japonicum.Then,PAE was orally administered before and after praziquantel treat-ment and both therapeutics were given simultaneously at different time points after the infection.The concentra-tion of serum hyaluronic acid(HA)was determined by radioimmunoassay(RIA).Hepatic granuloma and fib-rosis were evaluated via HE and Masson staining.The expression of α-smooth muscle actin(α-SMA),transform-ing growth factor β1(TGF-β1)and collagen I(Col I)protein was detected by immunohistochemistry.The effect of soluble egg antigen(SEA)and PAE on the pro-duction of TGF-β1 from mouse peritoneal macrophages(PMQs)was investigated by RT-PCR,Western blotting and ELISA.The effect of TGF-β1 in optimum macro-phage-conditioned medium(OPMCM)on the prolifera-tion of hepatic stellate cells(HSCs)and collagen secretion from HSCs with anti-TGF-β1 antibody was explored by MTT assay and ELISA.The results show that PAE could significantly reduce the concentration of serum HA,the size of egg granuloma,the severity of hepatic fibrosis and the expression of a-SMA,TGF-β1 and Col I protein in the pre-treatment group.However,in sim-or post-treatment group,PAE did not have any significant therapeutic effect.TGF-β1 could be secreted from PMQs stimulated by SEA.Meanwhile,the production of TGF-β1 from PMQs could be depressed significantly by PAE in a con-centration-dependent manner.TGF-β1 could promote the proliferation of HSCs and the secretion of collagens.In a word,PAE can prevent hepatic granuloma and fib-rosis caused by schistosomiasis japonica through the inhibition of the secretion of TGF-β1 from PMQs,the proliferation and activation of HSCs and the secretion of collagens from HSCs.Deyong CHU Conglei LI Qiang WU Jilong SHEN 2008Frontiers of Medicine2008,2,2:0
9Alternating Hemiplegia of Childhood Caused by ATP1A3 Mutations: A Report of Two Cases显示文摘Alternating hemiplegia of childhood is a rare neurodevelopmental disorder.Most cases are reported as sporadic disorder due to de novo variants,and few with family members involved.Two boys were hospitalized due to epileptic seizures occurred initially at age of six to seven months.During the course of the disease,there were repeated episodes of paroxysmal weakness or paralysis affecting one side of the body.Genetic testing showed that both patients carried heterozygous missense mutations in the ATP1A3 gene(OMIM:614820):c.3025(exon 22)A>G(p.K1009E)and c.2443(exon 18)G>A(p.E815K).Flunarizine can significantly improve the paroxysmal motor symptoms of pediatric patients with alternating hemiplegia.Guange Yang Zhongli Zhao Yang Yang Li Lin Conglei Song Xiaocui Wang Bin Yang 2021Chinese Medical Sciences Journal2021,36,2:0
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