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| 1 | Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury显示文摘The outbreak of the 2019-nCoV infection began in December 2019 in Wuhan,Hubei province,and rapidly spread to many provinces in China as well as other countries.Here we report the epidemiological,clinical,laboratory,and radiological characteristics,as well as potential biomarkers for predicting disease severity in 2019-nCoV-infected patients in Shenzhen,China.All 12 cases of the 2019-nCoV-infected patients developed pneumonia and half of them developed acute respiratory distress syndrome (ARDS).The most common laboratory abnormalities were hypoalbuminemia,lymphopenia,decreased percentage of lymphocytes (LYM) and neutrophils (NEU),elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH),and decreased CD8 count.The viral load of 2019-nCoV detected from patient respiratory tracts was positively linked to lung disease severity.ALB,LYM,LYM (%),LDH,NEU (%),and CRP were highly correlated to the acute lung injury.Age,viral load,lung injury score,and blood biochemistry indexes,albumin (ALB),CRP,LDH,LYM (%),LYM,and NEU (%),may be predictors of disease severity.Moreover,the Angiotensin Ⅱlevel in the plasma sample from 2019-nCoV infected patients was markedly elevated and linearly associated to viral load and lung injury.Our results suggest a number of potential diagnosis biomarkers and angiotensin receptor blocker (ARB) drugs for potential repurposing treatment of 2019-nCoV infection. | Yingxia Liu Yang Yang Cong Zhang Fengming Huang Fuxiang Wang Jing Yuan Zhaoqin Wang Jinxiu Li Jianming Li Cheng Feng Zheng Zhang Lifei Wang Ling Peng Li Chen Yuhao Qin Dandan Zhao Shuguang Tan Lu Yin Jun Xu Congzhao Zhou Chengyu Jiang Lei Liu | 2020 | Science China(Life Sciences)2020，63，3： | 157 |
| 2 | Magma mixing of granites at Lianghe:In-situ zircon analysis for trace elements, U-Pb ages and Hf isotopes显示文摘In this paper, we report an integrated study of trace element, U-Pb age and Hf isotopic composition of zircons from alkali feldspar granites, granodiorites and diorite enclaves in a recently discovered ring complex at Lianghe in western Yunnan, Chi na. The granitoids showed identical U-Pb ages of 127, 115 and 122 Ma, from felsic to mafic, but had different zircon trace el ements and Hf isotopic compositions. Trace element content decreased with a gradual increase in εHf(t) values of ?9.1 to ?5.4, ?4.5 to 0, and 3.6 to 6.2, respectively. Results indicate that changes in zircon trace elements generally correlate with changes in Hf isotope signatures within single samples and among various granitoids. These relationships reflect the mixing of felsic and mafic magmas. Evidence indicates that depleted mantle-derived mafic magma underplating caused ancient crustal melting, and then formed large-scale granites in Lianghe during the Early Cretaceous. These granodiorites were formed mainly by the mix ing of mafic magma and granitic magma. | CONG Feng LIN ShiLiang ZOU GuangFu LI ZaiHui XIE Tao PENG ZhiMin LIANG Ting | 2011 | Science China Earth Sciences2011，54，9： | 26 |
| 3 | Pyroptosis: mechanisms and diseases显示文摘Currently,pyroptosis has received more and more attention because of its association with innate immunity and disease.The research scope of pyroptosis has expanded with the discovery of the gasdermin family.A great deal of evidence shows that pyroptosis can affect the development of tumors.The relationship between pyroptosis and tumors is diverse in different tissues and genetic backgrounds.In this review,we provide basic knowledge of pyroptosis,explain the relationship between pyroptosis and tumors,and focus on the significance of pyroptosis in tumor treatment.In addition,we further summarize the possibility of pyroptosis as a potential tumor treatment strategy and describe the side effects of radiotherapy and chemotherapy caused by pyroptosis.In brief,pyroptosis is a double-edged sword for tumors.The rational use of this dual effect will help us further explore the formation and development of tumors,and provide ideas for patients to develop new drugs based on pyroptosis. | Pian Yu Xu Zhang Nian Liu Ling Tang Cong Peng Xiang Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 26 |
| 4 | Research on in-situ condition preserved coring and testing systems显示文摘As shallow resources are increasingly depleted,the mechanics'theory and testing technology of deep insitu rock has become urgent.Traditional coring technologies obtain rock samples without retaining the in-situ environmental conditions,leading to distortion of the measured parameters.Herein,a coring and testing systems retaining in-situ geological conditions is presented:the coring system that obtains in-situ rock samples,and the transfer and testing system that stores and analyzes the rocks under a reconstructed environment.The ICP-Coring system mainly consists of the pressure controller,active insulated core reactor and insulation layer and sealing film.The ultimate bearing strength of 100 MPa for pressurepreservation,temperature control accuracy of 0.97%for temperature-retained are realized.CH_(4)and CO permeability of the optimized sealing film are as low as 3.85 and 0.33 ppm/min.The average tensile elongation of the film is 152.4%and the light transmittance is reduced to 0%.Additionally,the pressure and steady-state temperature accuracy for reconstructing the in-situ environment of transfer and storage system up to 1%and±0.2 is achieved.The error recorded of the noncontact sensor ring made of lowdensity polymer is less than 6%than that of the contact test.The system can provide technical support for the deep in-situ rock mechanics research,improving deep resource acquisition capabilities and further clarifying deep-earth processes. | He-Ping Xie Tao Liu Ming-Zhong Gao Ling Chen Hong-Wei Zhou Yang Ju Feng Gao Xiao-Bo Peng Xiong-Jun Li Rui-Dong Peng Ya-Nan Gao Cong Li Zhi-Qiang He Ming-Qing Yang Zhi-Yu Zhao | 2021 | Petroleum Science2021，18，6： | 19 |
| 5 | Geochronology and Petrogenesis for the Protolith of Biotite Plagioclase Gneiss at Lianghe,Western Yunnan显示文摘在这份报纸,我们在西方的云南在 Lianghe 从黑云母斜长石片麻岩报导 U-Pb 年龄的综合研究和锆石的 Hf 同位素作文。锆石保存了继承核心和边界质地。火的锆石谷物和边界产出 120.4 的加权的吝啬的 206Pb/238U 年龄 ????晈 吗?? | CONG Feng LIN Shiliang ZOU Guangfu XIE Tao LI Zaihui TANG Fawei PENG Zhimin | 2011 | Acta Geologica Sinica(English Edition)2011，85，4： | 16 |
| 6 | Efficacy Evaluation for the Treatment of Subcapital Femoral Neck Fracture in Young Adults by Capsulotomy Reduction and Closed Reduction显示文摘 | Cong Liu Meng-Ting Liu Peng Li Hong-Hai Xu | 2015 | Chinese Medical Journal2015，，4： | 16 |
| 7 | Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson’s disease by regulating gut microbiota显示文摘The phenylalanine-tyrosine-dopa-dopamine pathway provides dopamine to the brain.Iin this process,tyrosine hydroxylase(TH)isthe rate-limiting enzyme that hydroxylates tyrosine and generates levodopa(L-dopa)with tetranydrobiopterin(BH_(4))as a coenzyme.Here,we show that oral berberine(BBR)might supply H^(·) through dihydroberberine(reduced BBR produced by bacterial nitroreductase)and promote the production of BHl from dihydrobiopterin;the increased BH,enhances TH activity,which accelerates the production of L-dopa by the gut bacteria.Oral BBR acts in a way similar to vitamins.The L-dopa produced by theintestinal bacteria enters the brain through the circulation and is transformed to dopamine.To verify the gut-brain dialog activatedby BBR's effect,Enterococcus foecalis or Enterococcus faecium was transplanted into Parkinson's disease(PD)mice.The bacteriasignificantly increased brain dopamine and ameliorated PD manifestation in mice;additionally,combination of BBR with bacteriashowed better therapeutic effect than that with bacteria alone.Moreover,2,4,6-trimethy-pyranylium tetrafluoroborate(TMP-TFB)-derivatized matrix-assisted laser desorption mass spectrometry(MALDI-MS)imaging of dopamine identihed elevated striataldopamine levels in mouse brains with oral Enterococcus,and BBR strengthened the imaging intensity of brain dopamine.Theseresults demonstrated that BBR was an agonist of TH in Enterococcus and could lead to the production of L-dopa in the gut.Furthermore,a study of 28 patients with hyperlipidemia conhrmed that oral BBR increased bloodfecal L-dopa by the intestinalbacteria.Hence,BBR might improve the brain function by upregulating the biosynthesis of-dopa in the gut microbiota through avitamin-like effect. | Yan Wang Qian Tong Shu-Rong Ma Zhen-Xiong Zhao Li-Bin Pan Lin Cong Pei Han Ran Peng Hang Yu Yuan Lin Tian-Le Gao Jia-Wen Shou Xiao-Yang Li Xian-Feng Zhang Zheng-Wei Zhang Jie Fu Bao-Ying Wen Jin-Bo Yu Xuetao Cao Jian-Dong Jiang | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 16 |
| 8 | Effective components of Chinese herbs reduce central nervous system function decline induced by iron overload显示文摘Abnormally increased levels of iron in the brain trigger cascade amplification in Alzheimer's disease patients,resulting in neuronal death.This study investigated whether components extracted from the Chinese herbs epimedium herb,milkvetch root and kudzuvine root could relieve the abnormal expression of iron metabolism-related protein in Alzheimer's disease patients.An APPswe/PS1ΔE9 double transgenic mouse model of Alzheimer's disease was used.The intragastric administration of compounds from epimedium herb,milkvetch root and kudzuvine root improved pathological alterations such as neuronal edema,increased the number of neurons,downregulated divalent metal transporter 1 expression,upregulated ferroportin 1 expression,and inhibited iron overload in the cerebral cortex of mice with Alzheimer's disease.These compounds reduced iron overload-induced impairment of the central nervous system,indicating a new strategy for developing novel drugs for the treatment of Alzheimer's disease. | Xian-hui Dong Jiang-tao Bai Wei-na Kong Xiao-ping He Peng Yan Tie-mei Shao Wen-guo Yu Xi-qing Chai Yan-hua Wu Cong Liu | 2015 | Neural Regeneration Research2015，10，5： | 14 |
| 9 | Hot air treatment activates defense responses and induces resistance against Botrytis cinerea in strawberry fruit显示文摘The effect of hot air(HA, 45°C, 3.5 h) treatment on reducing gray mold caused by Botrytis cinerea in strawberry fruit and the possible mechanisms were investigated. The results showed that HA treatment significantly reduced lesion diameter and enhanced activities of chitinase(CHI), β-1,3-glucanase and phenylalanine ammonia-lyase(PAL) in strawberry fruit. Total phenolic contents were also increased by HA treatment. The activities of antioxidant enzymes including superoxide dismutase(SOD), catalase(CAT) and ascorbate peroxidase(APX) were higher in HA treated strawberry fruit than those in control. Expression of three defense related genes such as CAT, CCR-1 allele and PLA6 was greatly induced in HA treated strawberry fruit with or without inoculation by B. cinerea. In addition, the in vitro experiment showed that HA treatment inhibited spore germination and tube growth of B. cinerea. These results suggested that HA treatment directly activated disease resistance against B. cinerea in strawberry fruit without priming response and directly inhibiting growth of B. cinerea. | JIN Peng ZHENG Cong HUANG Yu-ping WANG Xiao-li LUO Zi-sheng ZHENG Yong-hua | 2016 | Journal of Integrative Agriculture2016，15，11： | 10 |
| 10 | Molecular and cellular bases of chronic myeloid leukemia显示文摘Chronic myeloid leukemia(CML)is a myeloproliferative disease characterized by the overproduction of granulocytes,which leads to high white blood cell counts and splenomegaly in patients.Based on clinical symptoms and laboratory findings,CML is classified into three clinical phases,often starting with a chronic phase,progressing to an accelerated phase and ultimately ending in a terminal phase called blast crisis.Blast crisis phase of CML is clinically similar to an acute leukemia;in particular,B-cell acute lymphoblastic leukemia(B-ALL)is a severe form of acute leukemia in blast crisis,and there is no effective therapy for it yet.CML is induced by the BCR-ABL oncogene,whose gene product is a BCR-ABL tyrosine kinase.Currently,inhibition of BCR-ABL kinase activity by its kinase inhibitor such as imatinib mesylate(Gleevec)is a major therapeutic strategy for CML.However,the inability of BCR-ABL kinase inhibitors to completely kill leukemia stem cells(LSCs)indicates that these kinase inhibitors are unlikely to cure CML.In addition,drug resistance due to the development of BCRABL mutations occurs before and during treatment of CML with kinase inhibitors.A critical issue to resolve this problem is to fully understand the biology of LSCs,and to identify key genes that play significant roles in survival and self-renewal of LSCs.In this review,we will focus on LSCs in CML by summarizing and discussing available experimental results,including the original studies from our own laboratory. | Yaoyu Chen Cong Peng Dongguang Li Shaoguang Li | 2010 | Protein & Cell2010，1，2： | 10 |
| 11 | Study of a Novel Brain Relatively Specific Gene LRRC4 Involved in Glioma Tumorigenesis Suppression Using the Tet-on System显示文摘LRRC4 是新奇相对特定的基因,它在主要大脑肿瘤活体检视显示 significantdown 规定并且有潜力压制大脑 tumorgrowth.In 这研究,我们调查了生长在在由一个四圜素可诱导的表达式系统的 vitro 的房间增长上的 vivoand 的 tumorigencity 上的 LRRC4 的禁止的效果。结果证明 thatLRRC4 显著地减少了生长和从 glioblastomaU251MG 房间产生的异种皮移植的恶意的等级。在 U251MG Tet-on-LRRC4 细胞正式就职 withdoxycycline.Flow cytometry 和蛋白质印迹分析证明 LRRC4 调停了以后,细胞增长显著地被禁止在迟了的 G_1 的细胞周期的延期,可能通过起来调整 p21Wafl/cipl andp27Kipl 的表情并且下面调整 cyclin 依赖的激酶的表情 2, retinoblastoma 蛋白质和表皮的生长因素受体。一起,这些调查结果作为细胞生长的一个否定管理者提供线索给 LRRC4 的功能并且强调在 above-mentionedcyclins,联系 cyclin 的分子和 tumorigenicity 之间的一个连接。 | Qiu-Hong ZHANG Li-Li WANG Li CAO Cong PENG Xiao-Ling LI Ke TANG Wei-Fang LI Ping LIAO Jie-Ru WANG Gui-Yuan LI | 2005 | Acta Biochimica et Biophysica Sinica2005，37，8： | 9 |
| 12 | Study on the mechanism of copper-ammonia complex decomposition in struvite formation process and enhanced ammonia and copper removal显示文摘Heavy metals and ammonia are difficult to remove from wastewater,as they easily combine into refractory complexes.The struvite formation method(SFM) was applied for the complex decomposition and simultaneous removal of heavy metal and ammonia.The results indicated that ammonia deprivation by SFM was the key factor leading to the decomposition of the copper-ammonia complex ion.Ammonia was separated from solution as crystalline struvite,and the copper mainly co-precipitated as copper hydroxide together with struvite.Hydrogen bonding and electrostatic attraction were considered to be the main surface interactions between struvite and copper hydroxide.Hydrogen bonding was concluded to be the key factor leading to the co-precipitation.In addition,incorporation of copper ions into the struvite crystal also occurred during the treatment process. | Cong Peng Liyuan Chai Chongjian Tang Xiaobo Min Yuxia Song Chengshan Duan Cheng Yu | 2017 | Journal of Environmental Sciences2017，29，1： | 9 |
| 13 | An Energy-Efficient Data Collection Scheme Using Denoising Autoencoder in Wireless Sensor Networks显示文摘As one of the key operations in Wireless Sensor Networks(WSNs), the energy-efficient data collection schemes have been actively explored in the literature. However, the transform basis for sparsifing the sensed data is usually chosen empirically, and the transformed results are not always the sparsest. In this paper, we propose a Data Collection scheme based on Denoising Autoencoder(DCDA) to solve the above problem. In the data training phase, a Denoising AutoEncoder(DAE) is trained to compute the data measurement matrix and the data reconstruction matrix using the historical sensed data. Then, in the data collection phase, the sensed data of whole network are collected along a data collection tree. The data measurement matrix is utilized to compress the sensed data in each sensor node, and the data reconstruction matrix is utilized to reconstruct the original data in the sink.Finally, the data communication performance and data reconstruction performance of the proposed scheme are evaluated and compared with those of existing schemes using real-world sensed data. The experimental results show that compared to its counterparts, the proposed scheme results in a higher data compression rate, lower energy consumption, more accurate data reconstruction, and faster data reconstruction speed. | Guorui Li Sancheng Peng Cong Wang Jianwei Niu Ying Yuan | 2019 | Tsinghua Science and Technology2019，24，1： | 9 |
| 14 | Analysis of crack propagation in concrete structures with structural information entropy显示文摘The propagation of cracks in concrete structures causes energy dissipation and release, and also causes energy redistribution in the structures. Entropy can characterize the energy redistribution. To investigate the relation between the propagation of cracks and the entropy in concrete structures, cracked concrete structures are treated as dissipative structures. Structural information entropy is defined for concrete structures. A compact tension test is conducted. Meanwhile, numerical simulations are also carried out. Both the test and numerical simulation results show that the structural information entropy in the structures can characterize the propagation of cracks in concrete structures. | BAO TengFei1’2, PENG Yan1’2, CONG PeiJiang1’2 & WANG JiaLin1’2 1 State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering, Hohai University, Nanjing 210024, China 2 National Engineering Research Center ofWater Resources Efficient Utilization and Engineering Safety, Hohai University, Nanjing 210024, China | 2010 | Science China(Technological Sciences)2010，53，7： | 9 |
| 15 | Deep Tectonic Processes and Superaccumulation of Metals Related to Granitoids in the Nanling MetaUogenic Province,China显示文摘The Nanling region is an important nonferrous and rare metal metallogenic province in South China, in which most of the deposits are related to granitoids in genesis. It covers southern Hunan, southern Jiangxi, Guangxi, Guangdong and Fujian provinces, with a total area of about 550,000 km2. This metallogenic province is well known in the world for its rich tungsten and tin resources. In the past 40-odd years, a vast amount of mineral exploration activities and studies of the geology of mineral deposits have been carried out and great achievements obtained in the province. This paper is focused on a discussion about the deep tectonic processes in the orogenic belt during the Mesozoic and their contribution to the superaccumulation of metals. Tectonically, this metallogenic province is composed of three units: (1) the marginal continental orogenic belt in the Southeastern Coast fold system in the Yanshanian; (2) the intercontinental orogenic belt in the collision suture belt between the Yangtze and | PEI Rongfu, WANG Ping’an, and PENG Cong Institute of Mineral Deposits, CAGS, 26 Baiwanzhuang Rd., Beijing 100037 Institute of Geomechanics, CAGS, Beijing 100081 | 1999 | Acta Geologica Sinica(English Edition)1999，73，2： | 8 |
| 16 | No association between low-dose reserpine use and depression in older hypertensive patient: result of a multicenter, cross-sectional study显示文摘Background Reserpine is currently used by millions of Chinese hypertensive patients, in spite of the continued concern of its depressogenic effect, even when used in low dose. This study aimed to investigate the association between low-dose reserpine use and depression in older Chinese hypertensive patient. Methods In this cross-sectional, case-control study, we recruited patient aged 60 years or over who had regularly taken one or two tables of “compound reserpine and triamterene tablets (CRTTs)” for more than one year (reserpine user) from 26 community health centers located in 10 provinces in China. For each patient who took CRTTs, we selected an age (within five years) and sex matched hypertensive patient who had never taken any drugs containing reserpine (non-reserpine user) as control. Depressive symptoms were evaluated using a Chinese depression scale adapted from the Zung Self-Rating Depression Scale. Demographic, clinical data and laboratory examination results within six months were collected. Results From August 2018 to December 2018, 787 reserpine user and 787 non-reserpine user were recruited. The mean age of all study subjects was 70.3 years, with about equal numbers of males and females. The mean depression score was 40.4 in reserpine users and 40.6 in non-reserpine users (P = 0.7). The majority of study subject had a depression score < 53 (87.6% in reserpine users and 88.2% in non-reserpine users, respectively). There were no significant differences in the prevalence of mild, moderate or severe depression in reserpine users and non-reserpine users. Conclusions There is no association between low-dose reserpine use and depression in older hypertensive patient. The role of reserpine in the treatment and control of hypertension should be reconsidered;and further studies, especially randomized, controlled clinical trials to compare efficacy and safety of reserpine and other widely recommended anti-hypertensive agents are needed. | Guo-Hua ZHU Xi-Peng SUN Jing LI Lin PI Hai-Qin TANG Hai-Qing GAO Hong-Liang CONG Peng QU Xin-Zheng LU Xin-Jun ZHANG Luo-Sha ZHAO Yi-Fang GUO Dong-Xia LIU Liang-Qing ZHANG Hua TANG Yi-Xin HU Li FAN Qi HUA | 2019 | Journal of Geriatric Cardiology2019，16，8： | 8 |
| 17 | Multimodel projections and uncertainties of net ecosystem production in China over the twenty-first century显示文摘Ecosystems in China have been absorbing anthropogenic CO2 over the last three decades. Here, we assess future carbon uptake in China using models from phase 5 of Coupled Model Intercomparison Project under four socio-economic scenarios. The average of China's carbon sink from 2006 to 2100 represented by multimodel mean net ecosystem production(NEP) is projected to increase(relative to averaged NEP from 1976 to 2005) in the range of 0.137 and 0.891 Pg C a-1across differentscenarios. Increases in NEP are driven by increases in net primary production exceeding increases in heterotrophic respiration, and future carbon sink is mainly attributed to areas located in eastern China. However, there exists a considerable model spread in the magnitude of carbon sink and model spread tends to be larger when future climate change becomes more intense. The model spread may result from intermodel discrepancy in the magnitude of CO2 fertilization effect on photosynthesis, soil carbon turnover time, presence of carbon-nitrogen cycle and interpretation of land-use changes. For better quantifying future carbon cycle, a research priority toward improving model representation of these processes is recommended. | Tao Wang Xin Lin Shushi Peng Nan Cong Shilong Piao | 2014 | Chinese Science Bulletin2014，59，34： | 7 |
| 18 | V-disparity Based UGV Obstacle Detection in Rough Outdoor Terrain显示文摘 | CONG Yang PENG Jun-Jian SUN Jing ZHU Lin-Lin TANG Yan-Dong | 2010 | 自动化学报2010，36，5： | 7 |
| 19 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 20 | A stable artificial protective layer for high capacity dendrite-free lithium metal anode显示文摘The metallic lithium(Li)is considered as the most promising anode material for high-e nergy batteries.Nevertheless,the uncon trollable growth of Li den drite and un stable electrolyte/electrode in terface still hin der the developme nt of Li-based battery.In this work,a no vel strategy has been proposed to stabilize Li anode by in-situ polymerizing polypyrrole(PPy)layer on Ni foam(PPy@Ni foam)as an artificial protective layer.The PPy protective layer can effectively decrease the contact between Li metal and electrolyte during cycling.In addition,the morphology characterization shows that the PPy layer can help the even Li deposition undemeath the layer,leading to a dendrite-free Li anode.As a result,when deposited 2 mAh-cm-2 Li metal,the PPy@Ni foam can keep stable Coulombic efficiency(99%)during nearly 250 cycles,much better than the pure Ni foam(100 cycles).Even in the case of the Li capacity of 10 mAh-cm-2,the stable cycling performance for 60 cycles can still be achieved.Furthermore,when assembled with LiFePO4 material as the cathode for a full cell,the PPy@Ni foam can keep high capacity retention of 85.5%at 500 cycles.In our work,we provide a simple and effective method to enhanee the electrochemical performances of Li metal-based batteries,and reveal a new avenue to design three-dimensional(3D)metallic curre nt collector for protecting the Li metal ano de. | Zhipeng Wen Yueying Peng Jianlong Cong Haiming Hua Yingxin Lin Jian Xiong Jing Zeng Jinbao Zhao | 2019 | Nano Research2019，12，10： | 6 |
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