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| 1 | Role of colonoscopy in the diagnostic work-up of bowel endometriosis显示文摘AIM:To evaluate the accuracy of colonoscopy for the prediction of intestinal involvement in deep pelvic endometriosis.METHODS:This prospective observational study was performed between September 2011 and July 2014.Only women with both a clinical and imaging diagnosis of deep pelvic endometriosis were included.The study was approved by the local ethics committee and written informed consent was obtained in all cases.Both colonoscopy and laparoscopy were performed by expert surgeons with a high level of expertise with these techniques.Laparoscopy was performed within4 wk of colonoscopic examination.All hypothetical colonoscopy findings(eccentric wall thickening with or without surface nodularities and polypoid lesions with or without surface nodularities of endometriosis)were compared with laparoscopic and histological findings.We calculated the sensitivity,specificity,positive predictive value and negative predictive value for the presence of colonoscopic findings of intestinal endometriosis.RESULTS:A total of 174 consecutive women aged between 21-42 years with a diagnosis of deep pelvic endometriosis who underwent colonoscopy andsurgical intervention were included in our analysis.In 76 of the women(43.6%),intestinal endometrial implants were found at surgery and histopathological examination.Specifically,38 of the 76 lesions(50%)were characterized by the presence of serosal bowel nodules;28 of the 76 lesions(36.8%)reached the muscularis layer;8 of the 76 lesions(10.5%)reached the submucosa;and 2 of the 76 lesions(2.6%)reached the mucosa.Colonoscopic findings suggestive of intestinal endometriosis were detected in 7 of the174(4%)examinations.Colonoscopy failed to diagnose intestinal endometriosis in 70 of the 76 women(92.1%).A colonoscopic diagnosis of endometriosis was obtained in all cases of mucosal involvement,in 3of 8 cases(37.5%)of submucosal involvement,in no cases of muscularis layer involvement and in 1 of 38cases(2.6%)of serosa involvement.The sensitivity,specificity,positive predictive and negative predictive values of colonoscopy for the diagnosis of intestinal endometriosis were 7%,98%,85%and 58%,respectively.CONCLUSION:Being an invasive procedure,colonoscopy should not be routinely performed in the diagnostic work-up of bowel endometriosis. | Marco Milone Antonio Mollo Mario Musella Paola Maietta Loredana Maria Sosa Fernandez Olena Shatalova Alessandro Conforti Gianni Barone Giuseppe De Placido Francesco Milone | 2015 | World Journal of Gastroenterology2015，21，16： | 5 |
| 2 | Management of patients with melanoma and non-melanoma skin cancers in the coronavirus disease 2019 era显示文摘The recent coronavirus disease 2019(COVID-19)pandemic has completely disrupted hospital and outpatient activities.[1,2]It has been reorganized to allow a lower inflow of patients,to reduce non-urgent out-patient visits and to concentrate public health forces in the fight against the COVID-19 outbreak.In this reorganization,dermatology departments have also adapted their activities suspending routine patient visits and providing only urgent surgical removal,urgent visits,consultations,and oncological examinations. | Claudio Conforti Nicola di Meo Roberta Giuffrida Iris Zalaudek | 2020 | Chinese Medical Journal2020，，17： | 2 |
| 3 | Breast cancer molecularsub- classification and estrogen receptor expression to predict efficacyof adju- vant anthracycllnes-based chemotherapy: abiomarker study from two ran- domized trials显示文摘 | Conforti R Boulet T Tomasic G | 2007 | Ann Oncol2007，18，9： | 1 |
| 4 | A Ufd2/D4Cole le chimeric protein and over ex-pression of RbP7 in the slow Wallerian degeneration (Wlds) mouse显示文摘 | CONFORTI L TARLTON A MACK T G A | 2000 | Proc Natl Acad Sci2000，97，11： | 1 |
| 5 | Nitric Oxide synthase in the frog cerebellum: response of Purkinje neurons to unilateral eighth nerve transaction显示文摘 | Pisu MB Conforti E Botta L | 2002 | Anat Rec2002，268，： | 1 |
| 6 | Evaluation of performance characteristics of the medicinal leech(hirudo medicinalis) for the treatment of venous congestion显示文摘 | CONNOR N P HEISEY D M | 2002 | Plast Reconstr Surg2002，109，1： | 1 |
| 7 | Protection against neurodegenerative diseases of iris pseudopumila extracts and their constituents fitoterapia显示文摘 | Conforti F Rigano D Menichini F | | 0，，： | 1 |
| 8 | What drives faculty ratings of residents' clinical skills The impact of faculty's own clinical skills 显示文摘 | Kogan JR Hess B J Conforti LN | 2010 | Acad Med2010，85，10： | 1 |
| 9 | Mature and developing visual system of Ceratitis capitata (Diptera , Tephritidae) : histochemical evidence of nitric oxide synthase in the wild type and the white eye mutant strains显示文摘 | Conforti E Torti C Malacrida A R | 1999 | Brain Research1999，843，12： | 1 |
| 10 | NAD( + ) and axon degeneration revisited: Nmnatl cannot substitute for WldS to delay Wallerian degeneration 显示文摘 | Conforti L Fang G Beirowski B | 2007 | Cell Death Differ2007，14，1： | 1 |
| 11 | MMPll: a novel target antigen for cancer immunotherapy显示文摘 | Peruzzi D Moil F Conforti A | 2009 | Clin Can- cer Res2009，15，12： | 1 |
| 12 | State of art of recurrent lum- bar disk herniation, interspinous and interlumbar fusions 显示文摘 | Neroni M Gazzeri R Conforti G | 2014 | J Neu- rosurg Sci2014，58，21： | 1 |
| 13 | A potential role of alkaloid extracts from Salsola species (Chenopodiaceae) in the treatment of Alzheimer’s disease显示文摘 | Rosa Tundis Federica Menichini Filomena Conforti Monica R. Loizzo Marco Bonesi Giancarlo Statti Francesco Menichini | 2009 | Journal of Enzyme Inhibition and Medicinal Chemistry2009，，3： | 1 |
| 14 | Wld S protein re- quires Nmnat activity and a short N-terminal sequence to protect axons in mice 显示文摘 | Conforti L Wilbrey A Morreale G | 2009 | J Cell Biol2009，184，4： | 1 |
| 15 | Phenolic compounds from plants as nitric oxide production inhibitors显示文摘 | Conforti F Menichini F | 2011 | Curr Med Chem2011，18，8： | 1 |
| 16 | The management of Asherman syndrome : a review of literature 显示文摘 | Conforti A1 Alviggi C Mollo A | 2013 | Reprod Biol Endocrinol2013，，11： | 1 |
| 17 | Efficacy ofadjuvant chemotherapy according to prion protein expressionin patients with estrogen receptor-negative breast cancer显示文摘 | MESLIN F CONFORTI R MAZOUNI C | 2007 | Ann Oncol2007，18，6： | 1 |
| 18 | Three component process for the synthesis of 2-amino-2-chromenes in aqueous media显示文摘 | BALLINI R BOSICA G CONFORTI M L | 2001 | Tetrahedron2001，57，7： | 1 |
| 19 | Spontaneous resolution of eosinophilic granuloma in a patient with a psychotic disorder 显示文摘 | Conforti R Porto A Cirillo M | 2010 | Neuroradiol J2010，23，4： | 1 |
| 20 | Fluvastatin and hepatic reactions:a signal from spontaneous reporting in Italy显示文摘 | Conforti A Magro L Moretti U | 2006 | Drug Saf2006，29，12： | 1 |
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