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4篇 您的检索式:作者名="Cochonneau"
    题名 作者 年代 出处 被引量
1Contrasting iron isotopic compositions in river suspended matter: The Negro and the Amazon annual river cycles显示文摘Giana Márcia dos Santos Pinheiro Franck Poitrasson Francis Sondag Gérard Cochonneau Lucieth Cruz Vieira 2014Earth and Planetary Science Letters2014,,:1
2A monoclonal anti- body to O-Aeetyl-GD2 ganglioside and not to GD2 shows potent an- ti-tumor activity without peripheral nervous system cross-reactivity 显示文摘Alvarez-Rueda N Desselle A Cochonneau D 2011PLoS One2011,6,25:1
3The Development of Agroecology at Barani (Burkina Faso)显示文摘Jean Louis Yengue Maude Cochonneau 2013Journal of Agricultural Science and Technology(B)2013,3,8:1
4Biological evidence of cancer stem-like cells and recurrent disease in osteosarcoma显示文摘Sarcomas are a large family of cancers originating in the mesenchyme.Composed of more than 100 histological subtypes,soft tissue and bone sarcomas remain clinically challenging,particularly in children and adolescents in whom sarcomas are the second most common malignant entities.Osteosarcoma is the main primary bone tumor in adolescents and young adults and is characterized by a high propensity to induce distant metastatic foci and become multi-drug resistant.The innate and acquired resistance of osteosarcoma can be explained by high histological heterogeneity and genetic/molecular diversity.In the last decade,the notion of cancer stem-like cells(CSCs)has emerged.This subset of cancer cells has been linked to drug resistance properties,recurrence of the disease,and therapeutic failure.Although CSCs remain controversial,many elements are in favor of them playing a role in the development of the drug resistance profile.The present review gives a brief overview of the most recent biological evidence of the presence of CSCs in osteosarcomas and their role in the drug resistance profile of these rare oncological entities.Their use as promising therapeutic targets is discussed.Camille Jubelin Javier Munoz-Garcia Denis Cochonneau Emilie Moranton Marie-Francoise Heymann Dominique Heymann 2022Cancer Drug Resistance2022,5,1:0
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