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| 1 | Pre-and postoperative systemic hemodynamic evaluation in patients subjected to esophagogastric devascularization plus splenectomy and distal splenorenal shunt:A comparative study in schistomomal portal hypertension显示文摘AIM: To investigate the systemic hemodynamic effects of two surgical procedures largely employed for treatment of schistosomal portal hypertension. METHODS: Thirty-six patients undergoing elective surgical treatment of portal hypertension due to hepatosplenic mansonic schistosomiasis were prospectively evaluated. All patients were subjected to preoperative pulmonary artery catheterization; 17 were submitted to esophagogastric devascularization and splenectomy (EGDS) and 19 to distal splenorenal shunt (DSRS). The systemic hemodynamic assessment was repeated 4 d after the surgical procedure. RESULTS: Preoperative evaluation revealed (mean ± SD) an increased cardiac index (4.78 ± 1.13 L/min per m2),associated with a reduction in systemic vascular resistance index (1457 ± 380.7 dynes.s/cm5.m2). The mean pulmonary artery pressure (18 ± 5.1 mmHg) as well as the right atrial pressure (7.9 ± 2.5 mmHg) were increased,while the pulmonary vascular resistance index (133 ± 62 dynes.s/cm5.m2) was decreased. Four days after EGDS,a significant reduction in cardiac index (3.80 ± 0.4 L/min per m2,P < 0.001) and increase in systemic vascular resistance index (1901.4 ± 330.2 dynes.s/cm5. m2,P < 0.001) toward normal levels were observed. There was also a significant reduction in pulmonary artery pressure (12.65 ± 4.7 mmHg,P < 0.001) and no significant changes in the pulmonary vascular resistance index (141.6 ± 102.9 dynes.s/cm5.m2). Four days after DSRS,a non-significant increase in cardiac index (5.2 ± 0.76 L/min per m2) and systemic vascular resistance index (1389 ± 311 dynes.s/cm5.m2) was observed. There was also a non-significant increase in pulmonary artery pressure (19.84 ± 5.2 mmHg),right cardiac work index (1.38 ± 0.4 kg.m/m2) and right ventricular systolic work index (16.3 ± 6.3 g.m/m2),without significant changes in the pulmonary vascular resistance index (139.7 ± 67.8 dynes.s/cm5.m2). CONCLUSION: The hyperdynamic circulatory state observed in mansonic schistosomiasis was corrected by EGDS,but was maintained in patients who underwent DSRS. Similarly,the elevated mean pulmonary artery pressure was corrected after EGDS and maintained after DSRS. EGDS seems to be the most physiologic surgery for patients with schistosomal portal hypertension. | Roberto de Cleva Paulo Herman Luis Augusto Carneiro D’albuquerque Vincenzo Pugliese Orlando Luis Santarem William Abro Saad | 2007 | World Journal of Gastroenterology2007,13,41: | 9 |
| 2 | Postoperative portal vein thrombosis in patients with hepatosplenic mansonic schistosomia- sis: relationship with intraoperative portal pressure and flow: a prospective study 显示文摘 | De Cleva R Herman P Saad WA | 2005 | Hepatogastroenterology2005,52,65: | 1 |
| 3 | Bacterial translocation:over view of mechanicsms and clinical impact显示文摘 | Balzan S de Almeida Quadros C de Cleva R | 2007 | J Gastroenterol Hepatol2007,22,4: | 1 |
| 4 | Bacterial translocation:overview of mechanisms and clinical impact显示文摘 | Balzan S de Almeida Quadros C de Cleva R etal | 2007 | J Gastroenterol Hepatol2007,22,4: | 1 |
| 5 | Postoperative portal vein thrombosis in patients with hepatosplenic mansonic schistosomiasis:relationship with intraoperative portal pressure and flow显示文摘 | Cleva RD Herman P Saad WA | 2005 | Hepatogastroenterology2005,52,65: | 1 |
| 6 | Glutamatergic targets for enhancing extinction learning in drug addiction显示文摘 | Cleva RM Gass JT Widholm JJ | 2010 | CurrNeuropharmacol2010,8,4: | 1 |
| 7 | Status and origin of Haemonchinae (Nematoda: Trichostrongylidae) in deer: a survey conducted in France from 1985 to 1998显示文摘 | Ferte H Cleva D Depaquit J | 2000 | Parasitol Res2000,86,: | 1 |
| 8 | Bacterial translocation: overview of mechanisms and clinical impact显示文摘 | Balzan S de Ahneida Quadros C de Cleva R | 2007 | J Gastroenterol Hepatol2007,22,4: | 1 |
| 9 | Alcohol-seeking behavior is associated with increased glutamate transmission in baso-lateral amygdala and nucleus accumbens as measured by gluta-mate-oxidase-coated biosensors显示文摘 | Gass JT Sinclair CM Cleva RM | 2011 | Addict Biol2011,16,2: | 1 |
| 10 | Optical absorption measurements in monocrystalline sapphire at lpm 显示文摘 | Blair D Frederick Cleva | 1997 | Optical Materials1997,8,3: | 1 |
| 11 | Bacterial translocation:overview of mechanisms and clinical impact显示文摘 | Balzan S de Almeida Quadros C de Cleva R | 2007 | J Gastroenterol Hepatol2007,22,4: | 1 |
| 12 | Bacterial translocation:overview of mechanisms and clinical impact显示文摘 | Balzan S de Almeida Quadros C de Cleva R | 2007 | J Gastroenterol Hepatol2007,22,4: | 1 |
| 13 | Bacterial trans- location:overview of mechanisms and clinical impact显示文摘 | Balzan S de Almeida Quadros C de Cleva R | 2007 | J Gastro- enterol Hepato12007,22,10: | 1 |
| 14 | Tunable,superhydrophobically stable polymeric surfaces by electrospinning显示文摘 | Kazim Acatay Eren Simsek Cleva Ow-Yang | 2004 | Angew Chem Int Ed2004,43,39: | 1 |
| 15 | Postoperative portal vein thrombosis in patients with hepatosplenic mansonic schistosomiasis : relationship with intraoperative portal pressure and flow:a prospective study 显示文摘 | DE CLEVA R HERMAN P SAAD W A | 2005 | Hepatogastroenterology2005,52,65: | 1 |
| 16 | Subcellular and cellular locations of nitric oxide synthase isoforms as determinants of health and disease显示文摘 | Cleva Villanueva Cecilia Giulivi | 2010 | Free Radical Biology and Medicine2010,,3: | 1 |
| 17 | mGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol -seeking behavior显示文摘 | Sinclair CM Cleva RM Hood LE | | 0,,03: | 1 |
| 18 | Pulmonary artery catheter complications: report on a case of a knot accident and literature review显示文摘 | Lopes M C de Cleva R Zilberstein B Gama-Rodrigues J J | 2004 | Rev Hosp Clin Fac Med Sao Paulo2004,59,: | 1 |
| 19 | Bacterial translocation :Overview of mechamisms and clinical impact显示文摘 | Balzan S de almeida Quadros C De Cleva R | 2007 | J Gastroenterol Hepatol2007,22,10: | 1 |
| 20 | Acute renal failure due to abdominal compartment syndrome: report on 4cases and literature review 显示文摘 | Cleva R Silva FP Zilberstein B | 2001 | Rev Hosp Clin Fac Med Sao Paulo2001,56,4: | 1 |