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| 1 | Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration显示文摘AIM: To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fi ne-needle aspiration (EUS-FNA) for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions. METHODS: From January/1997 to December/2006, 611 patients with pancreatic tumors were subjected to EUS-FNA. The fi nal diagnosis was obtained either by surgery (356 cases) or after a mean clinical follow-up of 11.8 mo in the remaining patients. RESULTS: There were 405 solid tumors, 189 cystic lesions and 17 mixed. Pancreatic specimens for cytological assessment were successfully obtained by EUS-FNA in 595 (97.4/) cases. There were 352 (57.6/) malignancies and 259 (42.4/) benign tumors. Among the malignancies, pancreatic adenocarcinomas accounted for 67/ of the lesions. Overall, the sensitivity, specifi city, positive and negative predictive values, and accuracy of EUS-FNA were, respectively, 78.4/, 99.2/, 99.3/, 77.2/ and 87.2/. Specif ically for solid tumors, the same parameters for neoplasms larger and smaller than 3 cm were, respectively, 78.8/ vs 82.4/, 100/ vs 98.4/, 100/ vs 99/, 54.8/ vs 74.1/ and 83.1/ vs 87.8/. For cystic lesions, the values were, respectively, 72.2/, 99.3/, 97.5/, 91/ and 92.2/. CONCLUSION: EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions canreveal the best negative predictive value and diagnostic accuracy, both higher than 90/. | José Celso Ardengh César Vivian Lopes Luiz Felipe Pereira de Lima Juliano Rodrigues de Oliveira Filadélfi o Venco Giulio Cesare Santo José Luiz Pimenta Módena | 2007 | World Journal of Gastroenterology2007，13，22： | 17 |
| 2 | 过瘤胃蛋氨酸、赖氨酸和组氨酸对泌乳奶牛生产性能的影响显示文摘试验旨在研究饲料中单独添加或综合添加过瘤胃(RP)蛋氨酸、赖氨酸和组氨酸及可代谢蛋白(MP)对泌乳后期奶牛生产性能的影响。试验选取72头荷斯坦奶牛,随机分为6组,试验期9周。奶牛随机分配到6个试验组中,2周作为1个变量周期:MPA组,根据美国国家科学研究委员会(2001)标准,在饲料中添加调节MP到243 g·d-1;MPD组,不添加MP,MP含量低于标准量54 g·d-1;MPDM组,在MPD组的基础上加入RP蛋氨酸;MPDL组,在MPD组的基础上加入RP赖氨酸;MPDH组,在MPD组的基础上加入组氨酸;MPDMLH组,在MPD组的基础上加入RP蛋氨酸、RP赖氨酸和RP组氨酸。试验结果表明,与MPA组对比,MPD组的干物质采食量(DMI)、产奶量、乳成分(乳脂肪、乳蛋白和乳糖)及能量校正的牛乳(ECM)、ECM饲料利用效率、牛奶和血浆中的N均降低。在MPD基础上补充RP赖氨酸可使乳蛋白率、血浆中葡萄糖浓度增加,且牛奶中N元素含量有增加的趋势;补充RP组氨酸可使DMI、牛奶浓缩蛋白增加,且乳脂肪、乳蛋白和ECM显著增加;补充3种RP氨基酸时,增加了乳蛋白率,使DMI和乳脂率有增加趋势,也提高了乳脂肪、乳蛋白含量和ECM及ECM饲料利用效率。与MPA相比,MPD组牛奶中N的含量有降低趋势,且血浆中必需氨基酸(除赖氨酸和蛋氨酸)浓度均降低。补充RP赖氨酸、RP蛋氨酸和RP组氨酸提高了血浆中蛋氨酸(除MPDM组)、赖氨酸和组氨酸浓度。饲喂MPD的奶牛血红蛋白浓度降低,血浆生长素含量高于MPA组。MPD组牛奶中总饱和脂肪酸浓度有高于MPA和MPDMLH组的趋势。MPD组的多元不饱和脂肪、牛奶中奇链与支链脂肪酸含量与MPA组相比,有降低趋势。试验结果表明,对于饲料中缺乏MP的奶牛,在饲料中添加组氨酸和添加3种RP氨基酸(赖氨酸、蛋氨酸和组氨酸)均有提高牛奶产量和牛奶组分含量的可能性。 | Giallongo F Harper M T Oh J Lopes J C Lapierre H Patton R A Parys C Shinzato I Hristov A N | 2016 | 饲料博览2016，0，7： | 4 |
| 3 | Schistosoma mansoni: In vitro schistosomicidal activity ofpiplartine 显示文摘 | de Moraes J Nascimento C Lopes P O M V | 2011 | Exp Parasitol2011，127，2： | 1 |
| 4 | 'Very early' intrahepatic cholangiocarcinoma in cirrhotic patients:should liver transplantation be reconsidered in these patients?显示文摘 | Sapisochin G Rodriguez de Lope C Gastaca M | 2014 | Am J transplant2014，14，3： | 1 |
| 5 | Linear and nonlinear dynamics of cantilevered cylinders in axial flow, Part 2 : the equation of motion 显示文摘 | J L Lopes M P Paidoussis C Semler | 2002 | Journal of Fluids and Structures2002，16，6： | 1 |
| 6 | PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain显示文摘 | Rohacs T Lopes C M Michailidis I Logothetis D E | 2005 | Nat Neurosci2005，8，： | 1 |
| 7 | Response of antioxidant enzymes in freshwater fish populations (Leuciscus alburnides complex)to inorginanic pollu- tants exposure显示文摘 | Lopes P A Pinheiro T Santos M C | 2001 | Sci Total Environ2001，280，13： | 1 |
| 8 | Lunar and solar triggering of earthquakes显示文摘 | Lopes R M C Malin S R C Mazzarella A | 1990 | Physics of the Earth and Planetary interiors1990，59，： | 1 |
| 9 | Anti-inflammatory effect of physical training in heartfailure:role of TNF-alpha and IL-10显示文摘 | BATISTA M L Jr LOPES R D SEELAENDER M C | 2010 | Cardiol2010，95，2： | 1 |
| 10 | Ad- sorption of H2, CO2, CH4, CO, N2 and H20 in activa- ted carbon and zeolite for hydrogen production显示文摘 | LOPES F V S GRANDE C A RIBEIRO A M | 2009 | Sep- aration Science and Technology2009，，5： | 1 |
| 11 | Influence of cover crop on water use and performance of vineyard in Mediterranean Portugal显示文摘 | Monteiro A Lopes C M | 2007 | Agriculture Ecosystems and Environment2007，121，： | 1 |
| 12 | Developments in the rat adjuvant arthritis model and its use in therapeutic evaluation of novelnoninvasive treatment by SOD in transfersomes 显示文摘 | Simoes S I Delgado T C Lopes R M | 2005 | J Controlled Release2005，103，2： | 1 |
| 13 | Mechanical behaviour and bio- compatibility of poly (1-vinyl-2-pyrrolidinone)gelatin IPN hydrogels显示文摘 | Lopes C M Felisberti M I | 2003 | Biomaterials2003，24，7： | 1 |
| 14 | An Ab initio Study of the C2H2-HF,C2 H (CH3)-HF and C2 (CH3) 2-HF Hydrogen-Bonded Complexes显示文摘 | Ramos M N Lopes K C Venture E et at | | 0，，： | 1 |
| 15 | Effect of cigarette smoking on serum alpha-tocopherol and the lipid profile in a Portuguese population显示文摘 | LOPES P A SANTOS M C VICENTE L VIEGAS-CRESPO A M | 2004 | Clin Chim Acta2004，348，12： | 1 |
| 16 | Electric load fore- casting using a fuzzy ART&ARTMAP neural network显示文摘 | LOPES M L M MINUSSI C R LOTUFO A D P | 2005 | Applied Soft Computing2005，5，2： | 1 |
| 17 | Effects of Deficit Irrigation Strategies on Cluster Microclimate for Improving Fruit Composition of Moscatel field-grown Grapevines显示文摘 | Dos Santos T P Lopes C M Rodrigues M L | 2007 | Scientia Horticuhurae2007，112，3： | 1 |
| 18 | Variability of cork from Portuguese Quercus suber studied by solidstate C-13-NMR and FTIR spectroscopies显示文摘 | Lopes M Barrow A Veto C | 2001 | Biopolymers2001，62，： | 1 |
| 19 | Retrogression and re-aging of 7075 aluminium alloy: Microstructural characterization显示文摘 | VIANA F PINTO A M P SANTO H M C LOPES A B | 1999 | Materials Processing Technology1999，9293，： | 1 |
| 20 | Biological activities of α-pinene and β-pinene enantiomers 显示文摘 | Rivas da Silva A C Lopes P M Barros de Azevedo MM | 2012 | Molecules2012，17，6： | 1 |
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