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| 1 | Significance of antineutrophil cytoplasmic antibody in adult patients with Henoch-Schnlein purpura presenting mainly with gastrointestinal symptoms显示文摘AIM: To test the clinical significance of antineutrophil cytoplasmic antibody (ANCA) in evaluation of adult Henoch-Schnlein purpura (HSP) patients presenting mainly with abdominal symptoms. METHODS: Twenty-eight consecutive HSP patients who presented predominantly with abdominal symptoms were enrolled in this study. Control subjects included 27 age-and sex-matched patients with peptic ulcer disease,colon cancer,acute gastroenteritis,irritable bowel syndrome and colonic polyps. ANCA was measured by indirect immunofluorescence (ⅡF) in all patients,and follow-up ELISA was performed in patients with positive ⅡF tests. RESULTS: ANCA was detected in 9 HSP patients by ⅡF (2 were positive for c-ANCA and 7 were positive for p-ANCA). No ANCA was found in the control group. The sensitivity and specifi city of a positive ANCA test (either c-or p-ANCA) were 32.1% and 100% respectively. Only one out of the 9 patients with positive ANCA by ⅡF had positive ANCA by ELISA and the antigen was myeloperoxidase (MPO). The patients positive for ANCA had higher HSP clinical scores,and were more likely to have renal function impairment. Patients with late purpura development were also associated with more severe clinical manifestations. CONCLUSION: A positive ANCA test is associated with more severe symptoms in HSP. After inflammatory bowel disease is excluded,a positive ANCA test provides a clue to the diagnosis of HSP presenting predominantly with abdominal symptoms. | Yan Zhang Yong-Kang Wu Matthew A Ciorba Qin Ouyang | 2008 | World Journal of Gastroenterology2008，14，4： | 9 |
| 2 | Upper aerodigestive tract disorders and gastro-oesophageal reflux disease显示文摘A wide variety of symptoms and diseases of the upper aerodigestive tract are associated to gastro-oesophageal reflux disease(GORD). These disorders comprise a large variety of conditions such as asthma, chronic otitis media and sinusitis, chronic cough, and laryngeal disorders including paroxysmal laryngospasm. Laryngopharyngeal reflux disease is an extraoesophageal variant of GORD that can affect the larynx and pharynx. Despite numerous research efforts, the diagnosis of laryngopharyngeal reflux often remains elusive,unproven and controversial, and its treatment is then still empiric. Aim of this paper is to review the current literature on upper aerodigestive tract disorders in relation to pathologic gastro-oesophageal reflux, focusing in particular on the pathophysiology base and results of the surgical treatment of GORD. | Andrea Ciorba Chiara Bianchini Michele Zuolo Carlo Vittorio Feo | 2015 | World Journal of Clinical Cases2015，3，2： | 4 |
| 3 | Facial nerve paralysis in children显示文摘Facial nerve palsy is a condition with several implications, particularly when occurring in childhood. It represents a serious clinical problem as it causes significant concerns in doctors because of its etiology, its treatment options and its outcome, as well as in little patients and their parents, because of functional and aesthetic outcomes. There are several described causes of facial nerve paralysis in children, as it can be congenital(due to delivery traumas and genetic or malformative diseases) or acquired(due to infective,inflammatory, neoplastic, traumatic or iatrogenic causes). Nonetheless, in approximately 40%-75% of the cases, the cause of unilateral facial paralysis still remains idiopathic. A careful diagnostic workout and differential diagnosis are particularly recommended in case of pediatric facial nerve palsy, in order to establish the most appropriate treatment, as the therapeutic approach differs in relation to the etiology. | Andrea Ciorba Virginia Corazzi Veronica Conz Chiara Bianchini Claudia Aimoni | 2015 | World Journal of Clinical Cases2015，3，12： | 3 |
| 4 | Biomarkers in inflammatory bowel disease: current practices and recent advances显示文摘 | Heba N. Iskandar Matthew A. Ciorba | 2012 | Translational Research2012，，4： | 2 |
| 5 | Tinnitus and cochlear implants显示文摘 | Bovo R Ciorba A Martini A | 2011 | Auris Nasus Larynx2011，38，1： | 1 |
| 6 | Serum analysis of tryptophan catabolism pathway: Correlation with Crohn’s disease activity显示文摘 | Nitin K. Gupta Ameet I. Thaker Navya Kanuri Terrence E. Riehl Christopher W. Rowley William F. Stenson Matthew A. Ciorba | 2011 | Inflamm Bowel Dis2011，，7： | 1 |
| 7 | Pigmented villonod- ular synovitis of the temporomandibular joint 显示文摘 | Aimoni C Ciorba A Cappiello L | 2012 | J Craniofac Surg2012，23，2： | 1 |
| 8 | Five new OTOFgene mutations and auditory neuropathy显示文摘 | Zadro C Ciorba A Fabris A | 2010 | Int J Pedi-atr Otorhinolaryngol2010，74，5： | 1 |
| 9 | Head and neck cancer: The possible role of stem cells显示文摘 | Bianchini C Ciorba A Pelucchi S | 2008 | Eur Arch Otorhinolaryngol2008，265，1： | 1 |
| 10 | Auricular involvement of a multifocal non-AIDS Kaposi's sareoma:a case re port 显示文摘 | Busi M Altieri E Ciorba A | 2014 | Acta Otorhinolaryngol Ital2014，34，2： | 1 |
| 11 | Correlation Between Organic Component and Electrode Material: Consequences on Removal of Surfactants from Wastewater显示文摘 | George A Ciorba | 2000 | Electrochimica Acta2000，46，： | 1 |
| 12 | Postopera- tive complications in cochlear implants; a retrospec- tive analysis of 438 consecutive cases显示文摘 | CIORBA A BOVO R TREVISI P | 2012 | Eur Arch Otorhinolaryngol2012，269，： | 1 |
| 13 | Identifying congenital hearing impairment: preliminary results from a comparative study using objective and subjective audiometric protocols 显示文摘 | A Ciorba M Mazzoli A Pastore | 2013 | Acta otorhinolaryngologica Italica2013，33，1： | 1 |
| 14 | Vancomycin resistant enterococci healthcare associated infections显示文摘 | Orsi GB Ciorba V | 2013 | Ann Ig2013，25，48： | 1 |
| 15 | Tinnitus and cochlear implants 显示文摘 | Bovo R Ciorba A Martini A | 2011 | Auris Nasus Larynx2011，38，1： | 1 |
| 16 | The impact of hear-ing loss on the quality of life of elderly adults显示文摘 | Ciorba A Bianchini C Pelucchi S | 2012 | Clin IntervAging2012，7，： | 1 |
| 17 | Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/ cyclo-oxygenase-2-dependent manner显示文摘 | Ciorba MA Riehl TE Rao MS | 2012 | Gut2012，61，6： | 1 |
| 18 | Biloreral sudden profolud loss and ver- tigo as a unique manifestation of bilateral symmetric inferior pon- tine infurctions显示文摘 | Boror Orctore Ciorba A | 2007 | Ann Otol Rhionol Laryngol2007，116，60： | 1 |
| 19 | Microbial influences on the small intestinal response to radiation injury显示文摘 | Christopher D Packey Matthew A Ciorba | 2010 | Current Opinion in Gastroenterology2010，，2： | 1 |
| 20 | Probiotics as theraphy in gastroenterology:a study of physician opinions and recommendations显示文摘 | Williams MD Ha CY Ciorba MA | 2010 | J Clin Gastroentero12010，44，9： | 1 |
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